Biochemical and antiparasitic properties of inhibitors of the Plasmodium falciparum calcium-dependent protein kinase PfCDPK1

Antimicrobial Agents and Chemotherapy

Volumn 58, Issue 10, 2014, Pages 6032-6043

  Anseil, Keith H ^a   Jones, Hayley M ^a   Whalley, David ^a   Hearn, Alisdair ^a   Taylor, Debra L ^a   Patin, Emmanuel C ^a,c   Chapman, Timothy M ^a   Osborne, Simon A ^a   Wallace, Claire ^a   Birchall, Kristian ^a   Large, Jonathan ^a   Bouloc, Nathalie ^a   Smiljanic Hurley, Ela ^a   Clough, Barbara ^b   Moon, Robert W ^b   Green, Judith L ^b   Holder, Anthony A ^b  

^a MEDICAL RESEARCH COUNCIL   (United Kingdom)

^b NATIONAL INSTITUTE FOR MEDICAL RESEARCH   (United Kingdom)

^c CARDIFF UNIVERSITY SCHOOL OF MEDICINE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; AMINO ACID; PLASMODIUM FALCIPARUM CALCIUM DEPENDENT PROTEIN KINASE 1; PROTEIN KINASE; PROTEIN KINASE INHIBITOR; UNCLASSIFIED DRUG;

AMINO ACID SUBSTITUTION; ARTICLE; BINDING SITE; CHEMICAL ANALYSIS; CONTROLLED STUDY; DRUG ABSORPTION; DRUG DISTRIBUTION; DRUG EXCRETION; DRUG MECHANISM; DRUG METABOLISM; EC50; ENZYME INHIBITION; GROWTH INHIBITION; HIGH THROUGHPUT SCREENING; IC50; IN VITRO STUDY; MOLECULAR LIBRARY; NONHUMAN; PLASMODIUM BERGHEI; PLASMODIUM FALCIPARUM; PLASMODIUM VIVAX;

EID: 84907266459     PISSN: 00664804     EISSN: 10986596     Source Type: Journal    
DOI: 10.1128/AAC02959-14     Document Type: Article

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