Toxoplasma gondii calcium-dependent protein kinase 1 is a target for selective kinase inhibitors

Nature Structural and Molecular Biology

Volumn 17, Issue 5, 2010, Pages 602-607

  Ojo, Kayode K ^a   Larson, Eric T ^a,b   Keyloun, Katelyn R ^a   Castaneda, Lisa J ^a,b   Derocher, Amy E ^c   Inampudi, Krishna K ^a,c   Kim, Jessica E ^a,b   Arakaki, Tracy L ^a,b   Murphy, Ryan C ^d   Zhang, Li ^a,b   Napuli, Alberto J ^a,b   Maly, Dustin J ^d   Verlinde, Christophe L M J ^a,b   Buckner, Frederick S ^a,b   Parsons, Marilyn ^c,d   Hol, Wim G J ^a,b   Merritt, Ethan A ^a,b   Van Voorhis, Wesley C ^a,b,d  

^a UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^b Medical Structural Genomics of Pathogenic Protozoa Consortium ^*  (United States)

^c SEATTLE BIOMEDICAL RESEARCH INSTITUTE   (United States)

^d UNIVERSITY OF WASHINGTON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; CALCIUM DEPENDENT PROTEIN KINASE 1; CYSTEINE PROTEINASE; GLYCINE; METHIONINE; PHOSPHOTRANSFERASE INHIBITOR; UNCLASSIFIED DRUG;

ARTICLE; BINDING SITE; CELL INVASION; CRYSTAL STRUCTURE; DRUG TARGETING; HOST CELL; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; MAMMAL; NONHUMAN; PRIORITY JOURNAL; SENSITIVITY ANALYSIS; TOXOPLASMA GONDII; TOXOPLASMOSIS;

AMINO ACID SEQUENCE; ANIMALS; ANTIPARASITIC AGENTS; CRYSTALLOGRAPHY, X-RAY; FIBROBLASTS; HOST-PARASITE INTERACTIONS; HUMANS; MOLECULAR SEQUENCE DATA; PROTEIN CONFORMATION; PROTEIN KINASE INHIBITORS; PROTEIN KINASES; TOXOPLASMA; TOXOPLASMOSIS;

MAMMALIA; PYRONIA TITHONUS; TOXOPLASMA GONDII;

EID: 77951969562     PISSN: 15459993     EISSN: 15459985     Source Type: Journal    
DOI: 10.1038/nsmb.1818     Document Type: Article

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