Expression of the essential kinase PFCDPK1 from plasmodium falciparum in toxoplasma gondii facilitates the discovery of novel antimalarial drugs

Antimicrobial Agents and Chemotherapy

Volumn 58, Issue 5, 2014, Pages 2598-2607

  Gaji, Rajshekhar Y ^a   Checkley, Lisa ^b   Reese, Michael L ^c   Ferdig, Michael T ^b   Arrizabalaga, Gustavo ^a  

^a INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF NOTRE DAME   (United States)

^c UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIMALARIAL AGENT; DASATINIB; ENZYME; LESTAURTINIB; N [3 (5 CHLORO 1H PYRROLO[2,3 B]PYRIDINE 3 CARBONYL) 2,4 DIFLUOROPHENYL]PROPANESULFONAMIDE; NILOTINIB; PAZOPANIB; PLASMODIUM FALCIPARUM CALCIUM DEPENDENT PROTEIN KINASE1; PROTEIN KINASE; SORAFENIB; STAUROSPORINE; SUNITINIB; TOXOPLASMA GONDII CALCIUM DEPENDENT PROTEIN KINASE 3; UNCLASSIFIED DRUG; CALCIUM-DEPENDENT PROTEIN KINASE-1, PLASMODIUM FALCIPARUM; INDOLE DERIVATIVE; PROTOZOAL PROTEIN; PYRIMIDINE DERIVATIVE; SULFONAMIDE; THIAZOLE DERIVATIVE;

ARTICLE; CELL MEMBRANE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME LOCALIZATION; HUMAN; HUMAN CELL; MEROZOITE; NONHUMAN; PARASITE DEVELOPMENT; PLASMODIUM FALCIPARUM; PRIORITY JOURNAL; PROTEIN EXPRESSION; SECRETION (PROCESS); TOXOPLASMA GONDII; DRUG EFFECTS; FLUORESCENCE MICROSCOPY; IMMUNOBLOTTING; METABOLISM; TOXOPLASMA;

ANTIMALARIALS; CELL MEMBRANE; IMMUNOBLOTTING; INDOLES; MICROSCOPY, FLUORESCENCE; PLASMODIUM FALCIPARUM; PROTEIN KINASES; PROTOZOAN PROTEINS; PYRIMIDINES; SULFONAMIDES; THIAZOLES; TOXOPLASMA;

EID: 84898669963     PISSN: 00664804     EISSN: 10986596     Source Type: Journal    
DOI: 10.1128/AAC.02261-13     Document Type: Article

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