메뉴 건너뛰기




Volumn 42, Issue 5, 2014, Pages 1378-1382

New insight into the intracellular roles of class II phosphoinositide 3-kinases

Author keywords

Angiogenesis; Cilium; Endothelial cell; Phosphatidylinositol 3 phosphate (PI3K); Phosphoinositide 3 kinase (PI3K); Trafficking

Indexed keywords

PHOSPHATIDYLINOSITOL 3 KINASE; ISOENZYME; PHOSPHATIDYLINOSITOL 4 PHOSPHATE 3 KINASE; PIK3C2B PROTEIN, HUMAN; PIK3C2B PROTEIN, MOUSE; POLYPHOSPHOINOSITIDE; PROTEIN SUBUNIT; TUMOR PROTEIN;

EID: 84907218028     PISSN: 03005127     EISSN: 14708752     Source Type: Journal    
DOI: 10.1042/BST20140140     Document Type: Review
Times cited : (19)

References (36)
  • 1
    • 34247141906 scopus 로고    scopus 로고
    • Role of class II phosphoinositide 3-kinase in cell signalling
    • CrossRef PubMed
    • Falasca, M. and Maffucci, T. (2007) Role of class II phosphoinositide 3-kinase in cell signalling. Biochem. Soc. Trans. 35, 211-214 CrossRef PubMed
    • (2007) Biochem. Soc. Trans. , vol.35 , pp. 211-214
    • Falasca, M.1    Maffucci, T.2
  • 3
    • 84870017064 scopus 로고    scopus 로고
    • An introduction to phosphoinositides
    • PubMed
    • Maffucci, T. (2012) An introduction to phosphoinositides. Curr. Top. Microbiol. Immunol. 362, 1-42 PubMed
    • (2012) Curr. Top. Microbiol. Immunol. , vol.362 , pp. 1-42
    • Maffucci, T.1
  • 4
    • 80053095056 scopus 로고    scopus 로고
    • Phosphoinositide 3-kinase pathway inhibitors: Pharmacology, metabolism and drug development
    • CrossRef PubMed
    • Falasca, M. (2011) Phosphoinositide 3-kinase pathway inhibitors: pharmacology, metabolism and drug development. Curr. Med. Chem. 18, 2673 CrossRef PubMed
    • (2011) Curr. Med. Chem. , vol.18 , pp. 2673
    • Falasca, M.1
  • 5
    • 75849118878 scopus 로고    scopus 로고
    • Targeting the PI3K signaling pathway in cancer
    • CrossRef PubMed
    • Wong, K.K., Engelman, J.A. and Cantley, L.C. (2010) Targeting the PI3K signaling pathway in cancer. Curr. Opin. Genet. Dev. 20, 87-90 CrossRef PubMed
    • (2010) Curr. Opin. Genet. Dev. , vol.20 , pp. 87-90
    • Wong, K.K.1    Engelman, J.A.2    Cantley, L.C.3
  • 7
    • 84860206692 scopus 로고    scopus 로고
    • Regulation and cellular functions of class II phosphoinositide 3-kinases
    • CrossRef PubMed
    • Falasca, M. and Maffucci, T. (2012) Regulation and cellular functions of class II phosphoinositide 3-kinases. Biochem. J. 443, 587-601 CrossRef PubMed
    • (2012) Biochem. J. , vol.443 , pp. 587-601
    • Falasca, M.1    Maffucci, T.2
  • 10
    • 84870299287 scopus 로고    scopus 로고
    • Endothelial PI3K-C2α, a class II PI3K, has an essential role in angiogenesis and vascular barrier function
    • CrossRef PubMed
    • Yoshioka, K., Yoshida, K., Cui, H., Wakayama, T., Takuwa, N., Okamoto, Y., Du, W., Qi, X., Asanuma, K., Sugihara, K. et al. (2012) Endothelial PI3K-C2α, a class II PI3K, has an essential role in angiogenesis and vascular barrier function. Nat. Med. 18, 1560-1569 CrossRef PubMed
    • (2012) Nat. Med. , vol.18 , pp. 1560-1569
    • Yoshioka, K.1    Yoshida, K.2    Cui, H.3    Wakayama, T.4    Takuwa, N.5    Okamoto, Y.6    Du, W.7    Qi, X.8    Asanuma, K.9    Sugihara, K.10
  • 11
    • 84873802942 scopus 로고    scopus 로고
    • Essential role of class II phosphatidylinositol-3-kinase-C2 α in sphingosine 1-phosphate receptor-1-mediated signaling and migration in endothelial cells
    • CrossRef PubMed
    • Biswas, K., Yoshioka, K., Asanuma, K., Okamoto, Y., Takuwa, N., Sasaki, T. and Takuwa, Y. (2013) Essential role of class II phosphatidylinositol-3-kinase-C2 α in sphingosine 1-phosphate receptor-1-mediated signaling and migration in endothelial cells. J. Biol. Chem. 288, 2325-2339 CrossRef PubMed
    • (2013) J. Biol. Chem. , vol.288 , pp. 2325-2339
    • Biswas, K.1    Yoshioka, K.2    Asanuma, K.3    Okamoto, Y.4    Takuwa, N.5    Sasaki, T.6    Takuwa, Y.7
  • 12
    • 84897065629 scopus 로고    scopus 로고
    • PI3K class II α controls spatially restricted endosomal PtdIns3P and Rab11 activation to promote primary cilium function
    • CrossRef PubMed
    • Franco, I., Gulluni, F., Campa, C.C., Costa, C., Margaria, J.P., Ciraolo, E., Martini, M., Monteyne, D., De Luca, E., Germena, G. et al. (2014) PI3K class II α controls spatially restricted endosomal PtdIns3P and Rab11 activation to promote primary cilium function. Dev. Cell 28, 647-658 CrossRef PubMed
    • (2014) Dev. Cell , vol.28 , pp. 647-658
    • Franco, I.1    Gulluni, F.2    Campa, C.C.3    Costa, C.4    Margaria, J.P.5    Ciraolo, E.6    Martini, M.7    Monteyne, D.8    De Luca, E.9    Germena, G.10
  • 14
    • 0346095301 scopus 로고    scopus 로고
    • Targeted expression of the class II phosphoinositide 3-kinase in Drosophila melanogaster reveals lipid kinase-dependent effects on patterning and interactions with receptor signaling pathways
    • CrossRef PubMed
    • MacDougall, L.K., Gagou, M.E., Leevers, S.J., Hafen, E. and Waterfield, M.D. (2004) Targeted expression of the class II phosphoinositide 3-kinase in Drosophila melanogaster reveals lipid kinase-dependent effects on patterning and interactions with receptor signaling pathways. Mol. Cell Biol. 24, 796-808 CrossRef PubMed
    • (2004) Mol. Cell Biol. , vol.24 , pp. 796-808
    • MacDougall, L.K.1    Gagou, M.E.2    Leevers, S.J.3    Hafen, E.4    Waterfield, M.D.5
  • 15
    • 0029830237 scopus 로고    scopus 로고
    • The Drosophila phosphoinositide 3-kinase Dp110 promotes cell growth
    • PubMed
    • Leevers, S.J., Weinkove, D., MacDougall, L.K., Hafen, E. and Waterfield, M.D. (1996) The Drosophila phosphoinositide 3-kinase Dp110 promotes cell growth. EMBO J. 15, 6584-6594 PubMed
    • (1996) EMBO J , vol.15 , pp. 6584-6594
    • Leevers, S.J.1    Weinkove, D.2    MacDougall, L.K.3    Hafen, E.4    Waterfield, M.D.5
  • 16
    • 0029612196 scopus 로고
    • A family of phosphoinositide 3 kinases in Drosophila identifies a new mediator of signal transduction
    • CrossRef PubMed
    • MacDougall, L.K., Domin, J. and Waterfield, M.D. (1995) A family of phosphoinositide 3 kinases in Drosophila identifies a new mediator of signal transduction. Curr. Biol. 5, 1404-1415 CrossRef PubMed
    • (1995) Curr. Biol. , vol.5 , pp. 1404-1415
    • MacDougall, L.K.1    Domin, J.2    Waterfield, M.D.3
  • 18
    • 0029884657 scopus 로고    scopus 로고
    • Mouse p170 is a novel phosphatidylinositol 3-kinase containing a C2 domain
    • CrossRef PubMed
    • Virbasius, J.V., Guilherme, A. and Czech, M.P. (1996) Mouse p170 is a novel phosphatidylinositol 3-kinase containing a C2 domain. J. Biol. Chem. 271, 13304-13307 CrossRef PubMed
    • (1996) J. Biol. Chem. , vol.271 , pp. 13304-13307
    • Virbasius, J.V.1    Guilherme, A.2    Czech, M.P.3
  • 21
    • 26244461921 scopus 로고    scopus 로고
    • Phosphatidylinositol 3-kinase C2α is essential for ATP-dependent priming of neurosecretory granule exocytosis
    • CrossRef PubMed
    • Meunier, F.A., Osborne, S.L., Hammond, G.R., Cooke, F.T., Parker, P.J., Domin, J. and Schiavo, G. (2005) Phosphatidylinositol 3-kinase C2α is essential for ATP-dependent priming of neurosecretory granule exocytosis. Mol. Biol. Cell 16, 4841-4851 CrossRef PubMed
    • (2005) Mol. Biol. Cell , vol.16 , pp. 4841-4851
    • Meunier, F.A.1    Osborne, S.L.2    Hammond, G.R.3    Cooke, F.T.4    Parker, P.J.5    Domin, J.6    Schiavo, G.7
  • 22
    • 22344452002 scopus 로고    scopus 로고
    • Class II phosphoinositide 3-kinase defines a novel signaling pathway in cell migration
    • CrossRef PubMed
    • Maffucci, T., Cooke, F.T., Foster, F.M., Traer, C.J., Fry, M.J. and Falasca, M. (2005) Class II phosphoinositide 3-kinase defines a novel signaling pathway in cell migration. J. Cell Biol. 169, 789-799 CrossRef PubMed
    • (2005) J. Cell Biol. , vol.169 , pp. 789-799
    • Maffucci, T.1    Cooke, F.T.2    Foster, F.M.3    Traer, C.J.4    Fry, M.J.5    Falasca, M.6
  • 23
    • 77953516805 scopus 로고    scopus 로고
    • Insulin-feedback via PI3K-C2α activated PKBα/Akt1 is required for glucose-stimulated insulin secretion
    • CrossRef PubMed
    • Leibiger, B., Moede, T., Uhles, S., Barker, C.J., Creveaux, M., Domin, J., Berggren, P.O. and Leibiger, I.B. (2010) Insulin-feedback via PI3K-C2α activated PKBα/Akt1 is required for glucose-stimulated insulin secretion. FASEB J. 24, 1824-1837 CrossRef PubMed
    • (2010) FASEB J. , vol.24 , pp. 1824-1837
    • Leibiger, B.1    Moede, T.2    Uhles, S.3    Barker, C.J.4    Creveaux, M.5    Domin, J.6    Berggren, P.O.7    Leibiger, I.B.8
  • 26
    • 33644991658 scopus 로고    scopus 로고
    • Class II phosphoinositide 3-kinase α-isoform regulates Rho, myosin phosphatase and contraction in vascular smooth muscle
    • CrossRef PubMed
    • Wang, Y., Yoshioka, K., Azam, M.A., Takuwa, N., Sakurada, S., Kayaba, Y., Sugimoto, N., Inoki, I., Kimura, T., Kuwaki, T. and Takuwa, Y. (2006) Class II phosphoinositide 3-kinase α-isoform regulates Rho, myosin phosphatase and contraction in vascular smooth muscle. Biochem. J. 394, 581-592 CrossRef PubMed
    • (2006) Biochem. J. , vol.394 , pp. 581-592
    • Wang, Y.1    Yoshioka, K.2    Azam, M.A.3    Takuwa, N.4    Sakurada, S.5    Kayaba, Y.6    Sugimoto, N.7    Inoki, I.8    Kimura, T.9    Kuwaki, T.10    Takuwa, Y.11
  • 27
    • 33847174231 scopus 로고    scopus 로고
    • 2+-induced, Rho- and Rho kinase-dependent regulation of myosin phosphatase and contraction in isolated vascular smooth muscle cells
    • CrossRef PubMed
    • 2+-induced, Rho- and Rho kinase-dependent regulation of myosin phosphatase and contraction in isolated vascular smooth muscle cells. Mol. Pharmacol. 71, 912-920 CrossRef PubMed
    • (2007) Mol. Pharmacol. , vol.71 , pp. 912-920
    • Yoshioka, K.1    Sugimoto, N.2    Takuwa, N.3    Takuwa, Y.4
  • 30
    • 79958047958 scopus 로고    scopus 로고
    • Class II phosphoinositide 3-kinase C2α: What we learned so far
    • PubMed
    • Mazza, S. and Maffucci, T. (2011) Class II phosphoinositide 3-kinase C2α: what we learned so far. Int. J. Biochem. Mol. Biol. 2, 168-182 PubMed
    • (2011) Int. J. Biochem. Mol. Biol. , vol.2 , pp. 168-182
    • Mazza, S.1    Maffucci, T.2
  • 31
    • 0036325425 scopus 로고    scopus 로고
    • GLUT4 retention in adipocytes requires two intracellular insulin-regulated transport steps
    • CrossRef PubMed
    • Zeigerer, A., Lampson, M.A., Karylowski, O., Sabatini, D.D., Adesnik, M., Ren, M. and McGraw, T.E. (2002) GLUT4 retention in adipocytes requires two intracellular insulin-regulated transport steps. Mol. Biol. Cell 13, 2421-3245 CrossRef PubMed
    • (2002) Mol. Biol. Cell , vol.13 , pp. 2421-3245
    • Zeigerer, A.1    Lampson, M.A.2    Karylowski, O.3    Sabatini, D.D.4    Adesnik, M.5    Ren, M.6    McGraw, T.E.7
  • 32
    • 63349087876 scopus 로고    scopus 로고
    • Rab11 and its effector Rip11 participate in regulation of insulin granule exocytosis
    • CrossRef PubMed
    • Sugawara, K., Shibasaki, T., Mizoguchi, A., Saito, T. and Seino, S. (2009) Rab11 and its effector Rip11 participate in regulation of insulin granule exocytosis. Genes Cells 14, 445-456 CrossRef PubMed
    • (2009) Genes Cells , vol.14 , pp. 445-456
    • Sugawara, K.1    Shibasaki, T.2    Mizoguchi, A.3    Saito, T.4    Seino, S.5
  • 33
    • 84867044035 scopus 로고    scopus 로고
    • Regulation of endothelial cell morphogenesis by the protein kinase D (PKD)/glycogen synthase kinase 3 (GSK3)β pathway
    • CrossRef PubMed
    • Shin, S., Wolgamott, L. and Yoon, S.O. (2012) Regulation of endothelial cell morphogenesis by the protein kinase D (PKD)/glycogen synthase kinase 3 (GSK3)β pathway. Am. J. Physiol. Cell Physiol. 303, C743-C756 CrossRef PubMed
    • (2012) Am. J. Physiol. Cell Physiol. , vol.303 , pp. C743-C756
    • Shin, S.1    Wolgamott, L.2    Yoon, S.O.3
  • 34
    • 84865168855 scopus 로고    scopus 로고
    • Identification of somatic mutations in non-small cell lung carcinomas using whole-exome sequencing
    • CrossRef PubMed
    • Liu, P., Morrison, C., Wang, L., Xiong, D., Vedell, P., Cui, P., Hua, X., Ding, F., Lu, Y., James, M. et al. (2012) Identification of somatic mutations in non-small cell lung carcinomas using whole-exome sequencing. Carcinogenesis 33, 1270-1276 CrossRef PubMed
    • (2012) Carcinogenesis , vol.33 , pp. 1270-1276
    • Liu, P.1    Morrison, C.2    Wang, L.3    Xiong, D.4    Vedell, P.5    Cui, P.6    Hua, X.7    Ding, F.8    Lu, Y.9    James, M.10
  • 36
    • 84885385773 scopus 로고    scopus 로고
    • A class II phosphoinositide 3-kinase plays an indispensable role in hepatitis C virus replication
    • CrossRef PubMed
    • Maehama, T., Fukasawa, M., Date, T., Wakita, T. and Hanada, K. (2013) A class II phosphoinositide 3-kinase plays an indispensable role in hepatitis C virus replication. Biochem. Biophys. Res. Commun. 440, 150-156 CrossRef PubMed
    • (2013) Biochem. Biophys. Res. Commun. , vol.440 , pp. 150-156
    • Maehama, T.1    Fukasawa, M.2    Date, T.3    Wakita, T.4    Hanada, K.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.