Class II phosphoinositide 3-kinase regulates exocytosis of insulin granules in pancreatic β cells

Journal of Biological Chemistry

Volumn 286, Issue 6, 2011, Pages 4216-4225

  Dominguez, Veronica ^a   Raimondi, Claudio ^a   Somanath, Sangeeta ^a   Bugliani, Marco ^b   Loder, Merewyn K ^c   Edling, Charlotte E ^a   Divecha, Nullin ^d   Silva Xavier, Gabriela Da ^c   Marselli, Lorella ^b   Persaud, Shanta J ^e   Turner, Mark D ^a   Rutter, Guy A ^c   Marchetti, Piero ^b   Falasca, Marco ^a   Maffucci, Tania ^a  

^a QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

^b UNIVERSITY OF PISA   (Italy)

^c IMPERIAL COLLEGE LONDON   (United Kingdom)

^d UNIVERSITY OF MANCHESTER   (United Kingdom)

^e KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CELL MASS; CLASS II; DOWN-REGULATION; EXPRESSION LEVELS; IN-CELL; INSULIN GRANULES; INSULIN SECRETION; INSULINOMA CELLS; ISLETS OF LANGERHANS; ISOFORMS; PHOSPHOINOSITIDE 3-KINASE; PHOSPHOINOSITIDES; PLASMA MEMBRANES; TYPE-2 DIABETES;

CELL MEMBRANES; ENZYMES; GRANULATION; PHYSIOLOGY;

INSULIN;

PHOSPHATIDYLINOSITOL 3 KINASE; SYNAPTOSOMAL ASSOCIATED PROTEIN 25; INSULIN; ISOENZYME; MESSENGER RNA; PIK3C2A PROTEIN, HUMAN;

ANIMAL CELL; ARTICLE; CELL GROWTH; CELL MEMBRANE; CONTROLLED STUDY; DOWN REGULATION; ENZYME REGULATION; EXOCYTOSIS; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; INSULIN RELEASE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; NUCLEOTIDE SEQUENCE; PANCREAS ISLET; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; PROTEIN DEGRADATION; RAT; SIGNAL TRANSDUCTION; ANIMAL; BIOSYNTHESIS; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; SECRETION; SECRETORY VESICLE; TUMOR CELL LINE;

RATTUS;

ANIMALS; CELL LINE, TUMOR; DIABETES MELLITUS, TYPE 2; DOWN-REGULATION; EXOCYTOSIS; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMANS; INSULIN; INSULIN-SECRETING CELLS; ISOENZYMES; PHOSPHATIDYLINOSITOL 3-KINASES; RATS; RNA, MESSENGER; SECRETORY VESICLES; SYNAPTOSOMAL-ASSOCIATED PROTEIN 25;

EID: 79952997159     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M110.200295     Document Type: Article

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