High content analysis provides mechanistic insights on the pathways of toxicity induced by amine-modified polystyrene nanoparticles

PLoS ONE

Volumn 9, Issue 9, 2014, Pages

  Anguissola, Sergio ^a   Garry, David ^a   Salvati, Anna ^a   O'Brien, Peter J ^a   Dawson, Kenneth A ^a  

^a UNIVERSITY COLLEGE DUBLIN   (Ireland)

Author keywords

[No Author keywords available]

Indexed keywords

AMINE; NANOPARTICLE; PHOSPHOLIPID; POLYSTYRENE; POLYSTYRENE DERIVATIVE;

ACIDIFICATION; ACUTE TOXICITY; APOPTOSIS; ARTICLE; BIOACCUMULATION; CELL ASSAY; CELL LOSS; CELL VIABILITY; CHEMICAL ANALYSIS; CONCENTRATION (PARAMETERS); CONTENT ANALYSIS; CONTROLLED STUDY; CYTOTOXICITY; EMBRYO; ENDOTHELIUM CELL; GLIA CELL; HIGH CONTENT ANALYSIS; HUMAN; HUMAN CELL; IC50; KIDNEY CELL; LIVER CELL; LUNG ALVEOLUS CELL; LYSOSOME; MACROPHAGE; MITOCHONDRIAL MEMBRANE POTENTIAL; MOLECULAR DYNAMICS; MOLECULAR SIZE; NANOBIOTECHNOLOGY; PROCESS DEVELOPMENT; SENSITIVITY ANALYSIS; SIGNAL TRANSDUCTION; STEATOSIS; CELL LINE; CELL MEMBRANE; CHEMICALLY INDUCED; CHEMISTRY; DRUG EFFECTS; EVALUATION STUDY; FLOW CYTOMETRY; NANOTECHNOLOGY; NECROSIS; PROCEDURES; TOXICITY TESTING; ULTRASTRUCTURE;

APOPTOSIS; CELL LINE; CELL MEMBRANE; FLOW CYTOMETRY; HUMANS; LYSOSOMES; MEMBRANE POTENTIAL, MITOCHONDRIAL; NANOPARTICLES; NANOTECHNOLOGY; NECROSIS; POLYSTYRENES; TOXICITY TESTS;

EID: 84907216713     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0108025     Document Type: Article

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