A comparison of the effect of temperature and moisture on the solid dispersions: Aging and crystallization

International Journal of Pharmaceutics

Volumn 475, Issue 1, 2014, Pages 385-392

  Tian, Bin ^a   Zhang, Ling ^a   Pan, Zhendong ^a   Gou, Jingxin ^a   Zhang, Yu ^a   Tang, Xing ^a  

^a SHENYANG PHARMACEUTICAL UNIVERSITY   (China)

Author keywords

Aging; Crystallization; Dissolution; Moisture; Solid dispersion; Temperature

Indexed keywords

CINNARIZINE; MACROGOL DERIVATIVE; POLYVINYL CAPROLACTAM-POLYVINYL ACETATE-POLYETHYLENE GLYCOL GRAFT COPOLYMER; POLYVINYL DERIVATIVE; POWDER;

ARTICLE; CHEMICAL PROCEDURES; CONTROLLED STUDY; CRYSTALLIZATION; DIFFERENTIAL SCANNING CALORIMETRY; DISPERSION; DISSOLUTION; DRUG RELEASE; GLASS TRANSITION TEMPERATURE; HOT MELT EXTRUSION; HUMIDITY; MECHANICAL STRESS; MOISTURE; SOLID; SOLID STATE; TEMPERATURE; WATER VAPOR; X RAY POWDER DIFFRACTION; CHEMISTRY; DRUG STABILITY; HEAT; POWDER; PROCEDURES; SOLUBILITY; TRANSITION TEMPERATURE; X RAY DIFFRACTION;

CINNARIZINE; CRYSTALLIZATION; DRUG STABILITY; HOT TEMPERATURE; HUMIDITY; POLYETHYLENE GLYCOLS; POLYVINYLS; POWDERS; SOLUBILITY; TRANSITION TEMPERATURE; X-RAY DIFFRACTION;

EID: 84907189629     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2014.09.010     Document Type: Article

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