The identification of perillyl alcohol glycosides with improved antiproliferative activity

Journal of Medicinal Chemistry

Volumn 57, Issue 17, 2014, Pages 7478-7484

  Nandurkar, Nitin S ^a   Zhang, Jianjun ^a   Ye, Qing ^b   Ponomareva, Larissa V ^a   She, Qing Bai ^b   Thorson, Jon S ^a  

^a University of Kentucky   (United States)

^b UNIVERSITY OF KENTUCKY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 (PROP 1 EN 2 YL)CYCLOHEX 1 EN 1 YL]METHANOL; ANTINEOPLASTIC AGENT; METHOXY[[[4 (PROP 1 EN 2 YL)CYCLOHEX 1 EN 1 YL]METHYLIDENE]]AMINE; METHOXY[[[4 (PROP 1 EN 2 YL)CYCLOHEX 1 EN 1 YL]METHYL]]AMINE; PERILLYL ALCOHOL; UNCLASSIFIED DRUG; EIF4EBP1 PROTEIN, HUMAN; GLYCOSIDE; PHOSPHOPROTEIN; SIGNAL TRANSDUCING ADAPTOR PROTEIN; TERPENE;

ANTINEOPLASTIC ACTIVITY; ANTIPROLIFERATIVE ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG SYNTHESIS; GLYCOSYLATION; HUMAN; HUMAN CELL; IC50; IMMUNOBLOTTING; IN VITRO STUDY; MALE; PROTEIN PHOSPHORYLATION; PROTON NUCLEAR MAGNETIC RESONANCE; CELL PROLIFERATION; CELL SURVIVAL; CHEMICAL MODEL; CHEMICAL STRUCTURE; CHEMISTRY; DOSE RESPONSE; DRUG EFFECTS; METABOLISM; PHOSPHORYLATION; SYNTHESIS; TUMOR CELL LINE; WESTERN BLOTTING;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANTINEOPLASTIC AGENTS; BLOTTING, WESTERN; CELL LINE, TUMOR; CELL PROLIFERATION; CELL SURVIVAL; DOSE-RESPONSE RELATIONSHIP, DRUG; GLYCOSIDES; HUMANS; INHIBITORY CONCENTRATION 50; MODELS, CHEMICAL; MOLECULAR STRUCTURE; MONOTERPENES; PHOSPHOPROTEINS; PHOSPHORYLATION;

EID: 84907168866     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm500870u     Document Type: Article

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