Amphimedosides A-C: Synthesis, chemoselective glycosylation, and biological evaluation

Journal of Organic Chemistry

Volumn 78, Issue 4, 2013, Pages 1670-1676

  Langenhan, Joseph M ^a   Mullarky, Edouard ^a   Rogalsky, Derek K ^a   Rohlfing, James R ^a   Tjaden, Anja E ^a   Werner, Halina M ^a   Rozal, Leonardo M ^a   Loskot, Steven A ^a  

^a SEATTLE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALKOXYAMINES; BIOLOGICAL EVALUATION; CHEMOSELECTIVE; GLYCOSYLATED; HUMAN CANCER CELLS; NATURALLY OCCURRING; OXYAMINE; STEREO-SELECTIVE;

CHEMISTRY; ORGANIC COMPOUNDS;

CELL CULTURE;

14 (PYRIDIN 3 YL)TETRADEC 11 YN 1 AL; 14 (PYRIDIN 3 YL)TETRADEC 11 YN 1 AL O METHYL OXIME; 14 (PYRIDIN 3 YL)TETRADEC 11 YN 1 OL; 14 (PYRIDIN 3 YL)TETRADEC 9 YN 1 AL; 14 (PYRIDIN 3 YL)TETRADEC 9 YN 1 AL O METHYL OXIME; 14 (PYRIDIN 3 YL)TETRADEC 9 YNE 1 OL; 14 (PYRIDINE 3 YL) 1 (TERT BUTYLDIPHENYLSILYLOXY)TETRADEC 11 YNE; 14 (PYRIDINE 3 YL) 1 (TERT BUTYLDIPHENYLSILYLOXY)TETRADEC 9 YNE; 16 (PYRIDIN 3 YL) 1 (TERT BUTYLDIPHENYLSILYLOXY)HEXADEC 11 YNE; 16 (PYRIDIN 3 YL) HEXADEC 11 YN 1 OL; 16 (PYRIDIN 3 YL)HEXADEC 11 YN 1 AL; 16(PYRIDIN 3 YL)HEXADEC 11 YN 1 AL O METHYL OXIME; 3 (PYRIDIN 3 YL)BUT 1 YNE; 3 (PYRIDIN 3 YL)PROPANAL; AMPHIMEDOSIDE A; AMPHIMEDOSIDE B; AMPHIMEDOSIDE C; ANTINEOPLASTIC AGENT; O METHYL N[14 (PYRIDIN 3 YL)TETRADEC 11 YNYL]HYDROXYLAMINE; O METHYL N[14 (PYRIDIN 3 YL)TETRADEC 11 YNYL]HYDROXYLAMINE BETA GLUCOPYRANOSIDE; O METHYL N[14 (PYRIDIN 3 YL)TETRADEC 9 YNYL]HYDROXYLAMIN; O METHYL N[14 (PYRIDIN 3 YL)TETRADEC 9 YNYL]HYDROXYLAMIN BETA GLUCOPYRANOSIDE; O METHYL N[16 (PYRIDIN 3 YL)HEXADEC 11 YNYL]HYDROXYAMINE BETA GLUCOPYRANOSIDE; O METHYL N[16 (PYRIDIN 3 YL)HEXADEC 11 YNYL]HYDROXYLAMINE; PYRIDINE DERIVATIVE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; BREAST ADENOCARCINOMA; CANCER CELL CULTURE; COLORECTAL CARCINOMA; CYTOTOXICITY TEST; DRUG STRUCTURE; DRUG SYNTHESIS; EVALUATION; GLYCOSYLATION; HUMAN; HUMAN CELL; IC 50; LIVER CELL CARCINOMA; LUNG ADENOCARCINOMA; MELANOMA; PROSTATE CARCINOMA; STEREOCHEMISTRY;

ALKALOIDS; AMINO SUGARS; ANTINEOPLASTIC AGENTS; CELL LINE; CELL LINE, TUMOR; DRUG SCREENING ASSAYS, ANTITUMOR; GLYCOSYLATION; HUMANS; INHIBITORY CONCENTRATION 50; STEREOISOMERISM;

EID: 84873965100     PISSN: 00223263     EISSN: 15206904     Source Type: Journal    
DOI: 10.1021/jo302640y     Document Type: Article

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