Ligands for FKBP12 increase Ca2+influx and protein synthesis to improve skeletal muscle function

Journal of Biological Chemistry

Volumn 289, Issue 37, 2014, Pages 25556-25570

  Lee, Chang Seok ^a   Georgiou, Dimitra K ^a   Dagnino Acosta, Adan ^a   Xu, Jianjun ^a,e   Ismailov, Iskander I ^a,f   Knoblauch, Mark ^a   Monroe, Tanner O ^a   Ji, Rui Rui ^a   Hanna, Amy D ^a   Joshi, Aditya D ^a   Long, Cheng ^a,g   Oakes, Joshua ^a   Tran, Ted ^a   Corona, Benjamin T ^b   Lorca, Sabina ^c   Ingalls, Christopher P ^b   Narkar, Vihang A ^c   Lanner, Johanna T ^a,h   Bayle, J Henri ^a   Durham, William J ^d   Hamilton, Susan L ^a   more..

^a BAYLOR COLLEGE OF MEDICINE   (United States)

^b GEORGIA STATE UNIVERSITY   (United States)

^c UNIVERSITY OF TEXAS   (United States)

^d University of Texas Medical Branch School of Medicine   (United States)

^e KAGOSHIMA UNIVERSITY   (Japan)

^f VIRGINIA TECH CARILION SCHOOL OF MEDICINE   (United States)

^g SOUTH CHINA NORMAL UNIVERSITY   (China)

^h KAROLINSKA INSTITUTE   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM; CHELATION; LIGANDS; MAMMALS; MUSCLE; PROTEINS;

CARDIAC FUNCTIONS; MAMMALIAN TARGET; MUSCLE FATIGUES; MUSCLE FUNCTION; PROTEIN SYNTHESIS; SARCOPLASMIC RETICULUM; SKELETAL MUSCLE; SYNTHETIC LIGANDS;

BIOSYNTHESIS;

CALCIUM ION; PROTEIN INHIBITOR; RAPAMYCIN; RYANODINE RECEPTOR 1; SYNTHETIC LIGAND FOR FKBP12; UNCLASSIFIED DRUG; FK 506 BINDING PROTEIN; LIGAND; MECHANISTIC TARGET OF RAPAMYCIN COMPLEX 1; MULTIPROTEIN COMPLEX; PROTEIN BINDING; TARGET OF RAPAMYCIN KINASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; DOSE RESPONSE; DRUG ACTIVITY; DRUG MEGADOSE; GRIP STRENGTH; HEART FUNCTION; LIGAND BINDING; LOW DRUG DOSE; MOUSE; MUSCLE EXERCISE; MUSCLE FATIGUE; MUSCLE FUNCTION; NONHUMAN; PATHOGENESIS; PROTEIN DEPLETION; PROTEIN PROTEIN INTERACTION; PROTEIN SYNTHESIS; SARCOPLASMIC RETICULUM; SIGNAL TRANSDUCTION; SKELETAL MUSCLE; TREATMENT DURATION; ANIMAL; CALCIUM SIGNALING; CHEMISTRY; DRUG EFFECTS; GENETICS; GROWTH, DEVELOPMENT AND AGING; METABOLISM; MUSCLE CONTRACTION;

ANIMALS; CALCIUM SIGNALING; DOSE-RESPONSE RELATIONSHIP, DRUG; LIGANDS; MICE; MULTIPROTEIN COMPLEXES; MUSCLE CONTRACTION; MUSCLE, SKELETAL; PROTEIN BINDING; PROTEIN BIOSYNTHESIS; SARCOPLASMIC RETICULUM; SIROLIMUS; TACROLIMUS BINDING PROTEIN 1A; TOR SERINE-THREONINE KINASES;

EID: 84907168732     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M114.586289     Document Type: Article

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