A novel insulin receptor-binding protein from Momordica charantia enhances glucose uptake and glucose clearance in vitro and in vivo through triggering insulin receptor signaling pathway

Journal of Agricultural and Food Chemistry

Volumn 62, Issue 36, 2014, Pages 8952-8961

  Lo, Hsin Yi ^a   Ho, Tin Yun ^a   Li, Chia Cheng ^a   Chen, Jaw Chyun ^b   Liu, Jau Jin ^a   Hsiang, Chien Yun ^a  

^a CHINA MEDICAL UNIVERSITY   (Taiwan)

^b DA YEH UNIVERSITY   (Taiwan)

Author keywords

diabetes; glucose homeostasis; insulin receptor binding protein; Momordica charantia

Indexed keywords

GLUCOSE HOMEOSTASIS; GLUCOSE UPTAKE; IN-VITRO; INSULIN RECEPTORS; MOMORDICA CHARANTIA; RECEPTOR-BINDING PROTEINS;

MEDICAL PROBLEMS;

ANTIDIABETIC AGENT; CARRIER PROTEIN; GLUCOSE; INSULIN RECEPTOR; MOMORDICA CHARANTIA TRYPSIN INHIBITOR II'; PROTEIN BINDING; TRYPSIN INHIBITOR; VEGETABLE PROTEIN;

3T3 CELL LINE; ANIMAL; BAGG ALBINO MOUSE; BINDING SITE; CHEMICAL STRUCTURE; CHEMISTRY; DRUG EFFECTS; EXPERIMENTAL DIABETES MELLITUS; ISOLATION AND PURIFICATION; MALE; METABOLISM; MOMORDICA CHARANTIA; MOUSE; PHYSIOLOGY; SIGNAL TRANSDUCTION;

3T3-L1 CELLS; ANIMALS; BINDING SITES; CARRIER PROTEINS; DIABETES MELLITUS, EXPERIMENTAL; GLUCOSE; HYPOGLYCEMIC AGENTS; MALE; MICE; MICE, INBRED BALB C; MODELS, MOLECULAR; MOLECULAR STRUCTURE; MOMORDICA CHARANTIA; PLANT PROTEINS; PROTEIN BINDING; RECEPTOR, INSULIN; SIGNAL TRANSDUCTION; TRYPSIN INHIBITORS;

EID: 84907164545     PISSN: 00218561     EISSN: 15205118     Source Type: Journal    
DOI: 10.1021/jf5002099     Document Type: Article

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