Genipin inhibits lipopolysaccharide-induced acute systemic inflammation in mice as evidenced by nuclear factor-κB bioluminescent imaging-guided transcriptomic analysis

Food and Chemical Toxicology

Volumn 50, Issue 9, 2012, Pages 2978-2986

  Li, Chia Cheng ^a   Hsiang, Chien Yun ^a   Lo, Hsin Yi ^a   Pai, Fu Tzu ^a   Wu, Shih Lu ^a   Ho, Tin Yun ^a,b  

^a CHINA MEDICAL UNIVERSITY   (Taiwan)

^b CHINA MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

Author keywords

Bioluminescent imaging; DNA microarray; Genipin; Nuclear factor B; Systemic inflammation

Indexed keywords

CHEMOKINE RECEPTOR; GENIPIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; LIPOPOLYSACCHARIDE; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; BIOLUMINESCENT IMAGING; CHEMOKINE LIGAND GENE; CHEMOKINE RECEPTOR GENE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DOSE RESPONSE; DOWN REGULATION; DRUG DOSE COMPARISON; DRUG EFFICACY; FEMALE; GENE; GENE EXPRESSION REGULATION; IMAGING; IN VITRO STUDY; IN VIVO STUDY; INFLAMMATION; INTERFERON INDUCED PROTEIN GENE; LUCIFERASE GENE; MICROARRAY ANALYSIS; MOUSE; NONHUMAN; PROTEIN BLOOD LEVEL; PROTEIN SYNTHESIS INHIBITION; REAL TIME POLYMERASE CHAIN REACTION; SYSTEMIC INFLAMMATION; TISSUE LEVEL; TRANSCRIPTOMICS; TRANSGENIC MOUSE;

ANIMALS; CELL LINE; ENZYME-LINKED IMMUNOSORBENT ASSAY; GENE EXPRESSION PROFILING; HUMANS; IMMUNOHISTOCHEMISTRY; INFLAMMATION; IRIDOIDS; LIPOPOLYSACCHARIDES; LUMINESCENCE; MICE; NF-KAPPA B; REAL-TIME POLYMERASE CHAIN REACTION; TRANSCRIPTOME;

MUS; MUS MUSCULUS;

EID: 84864067831     PISSN: 02786915     EISSN: 18736351     Source Type: Journal    
DOI: 10.1016/j.fct.2012.05.054     Document Type: Article

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