Insulin sensitization via partial agonism of PPARγ and glucose uptake through translocation and activation of GLUT4 in PI3K/p-Akt signaling pathway by embelin in type 2 diabetic rats

Biochimica et Biophysica Acta - General Subjects

Volumn 1830, Issue 1, 2013, Pages 2243-2255

  Gandhi, Gopalsamy Rajiv ^a   Stalin, Antony ^a   Balakrishna, Kedike ^a   Ignacimuthu, Savarimuthu ^a   Paulraj, Michael Gabriel ^a   Vishal, Rajagopal ^b  

^a LOYOLA COLLEGE   (India)

^b UNIVERSITY OF MADRAS   (India)

Author keywords

Embelin; GLUT4; Molecular docking; PI3K p Akt; PPAR ; Type 2 diabetes mellitus

Indexed keywords

EMBELIA RIBES EXTRACT; EMBELIN; GLUCOSE; GLUCOSE TRANSPORTER 4; INSULIN SENSITIZING AGENT; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA AGONIST; PHOSPHATIDYLINOSITOL 3 KINASE; PLANT EXTRACT; PROTEIN KINASE B; ROSIGLITAZONE; STREPTOZOCIN; UNCLASSIFIED DRUG;

ADIPOSE TISSUE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIDIABETIC ACTIVITY; ANTIOXIDANT ACTIVITY; ARTICLE; BINDING AFFINITY; CELL PROTECTION; CHOLESTEROL LIVER LEVEL; CONTROLLED STUDY; DISEASE ASSOCIATION; DRUG ISOLATION; DRUG PROTEIN BINDING; DRUG SCREENING; EMBELIA RIBES; EPIDIDYMIS; EXPERIMENTAL RAT; FRUIT; GLUCOSE BLOOD LEVEL; GLUCOSE HOMEOSTASIS; GLUCOSE TRANSPORT; GLYCEMIC CONTROL; INSULIN BLOOD LEVEL; INSULIN SENSITIVITY; LIPID ANALYSIS; MALE; MOLECULAR DOCKING; MUSCLE LEVEL; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; OBESITY; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; PROTEIN LOCALIZATION; RAT; SENSITIZATION; SIGNAL TRANSDUCTION; STREPTOZOCIN DIABETES; WEIGHT REDUCTION;

ADIPOSE TISSUE; ANIMALS; BENZOQUINONES; DIABETES MELLITUS, EXPERIMENTAL; DIABETES MELLITUS, TYPE 2; EMBELIA; FRUIT; GENE EXPRESSION REGULATION; GLUCOSE; GLUCOSE TRANSPORTER TYPE 4; HOMEOSTASIS; HYPOGLYCEMIC AGENTS; INSULIN RESISTANCE; INSULIN-SECRETING CELLS; MALE; OBESITY; PHOSPHATIDYLINOSITOL 3-KINASES; PPAR GAMMA; PROTEIN TRANSPORT; PROTO-ONCOGENE PROTEINS C-AKT; RATS; RATS, WISTAR; SIGNAL TRANSDUCTION;

EMBELIA RIBES; MYRSINACEAE; RATTUS;

EID: 84868708334     PISSN: 03044165     EISSN: 18728006     Source Type: Journal    
DOI: 10.1016/j.bbagen.2012.10.016     Document Type: Article

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