메뉴 건너뛰기




Volumn 2, Issue 1, 2012, Pages 10-16

DNA microarray analysis as a tool to investigate the therapeutic mechanisms and drug development of Chinese medicinal herbs

Author keywords

DNA microarray; Gene expression profile; Traditional Chinese medicine

Indexed keywords

ANTHRAQUINONE; ARISTOLOCHIC ACID; COMPLEMENTARY DNA; CURCUMIN; GINKGO BILOBA EXTRACT; LIUWEIDIHUANG TANG; OLIGONUCLEOTIDE; PC SPES; PINELLIAE RHIZOMA EXTRACT; PLANT EXTRACT; PLANT MEDICINAL PRODUCT; SAN HUANG XIE XIN TANG; UNCLASSIFIED DRUG; VANILLIN;

EID: 84862784657     PISSN: 22118020     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biomed.2012.02.002     Document Type: Review
Times cited : (23)

References (52)
  • 1
    • 0028806048 scopus 로고
    • Quantitative monitoring of gene expression patterns with a complementary DNA microarray
    • Schena M., Shalon D., Davis R.W., Brown P.O. Quantitative monitoring of gene expression patterns with a complementary DNA microarray. Science 1995, 270:467-470.
    • (1995) Science , vol.270 , pp. 467-470
    • Schena, M.1    Shalon, D.2    Davis, R.W.3    Brown, P.O.4
  • 2
    • 70349372192 scopus 로고    scopus 로고
    • Introduction to microarray technology
    • Dufva M. Introduction to microarray technology. Methods Mol Biol 2009, 529:1-22.
    • (2009) Methods Mol Biol , vol.529 , pp. 1-22
    • Dufva, M.1
  • 3
    • 31444431754 scopus 로고    scopus 로고
    • Reliability and reproducibility issues in DNA microarray measurements
    • Draghici S., Khatri P., Eklund A.C., Szallasi Z. Reliability and reproducibility issues in DNA microarray measurements. Trends Genet 2006, 22:101-109.
    • (2006) Trends Genet , vol.22 , pp. 101-109
    • Draghici, S.1    Khatri, P.2    Eklund, A.C.3    Szallasi, Z.4
  • 4
    • 7444234286 scopus 로고    scopus 로고
    • Getting the noise out of gene arrays
    • Marshall E. Getting the noise out of gene arrays. Science 2004, 306:630-631.
    • (2004) Science , vol.306 , pp. 630-631
    • Marshall, E.1
  • 5
    • 77549088298 scopus 로고    scopus 로고
    • Microarray data quality control improves the detection of differentially expressed genes
    • Kauffmann A., Huber W. Microarray data quality control improves the detection of differentially expressed genes. Genomics 2010, 95:138-142.
    • (2010) Genomics , vol.95 , pp. 138-142
    • Kauffmann, A.1    Huber, W.2
  • 6
    • 18344396568 scopus 로고    scopus 로고
    • Minimum information about a microarray experiment (MIAME)-toward standards for microarray data
    • Brazma A., Hingamp P., Quackenbush J., Sherlock G., Spellman P., Stoeckert C., et al. Minimum information about a microarray experiment (MIAME)-toward standards for microarray data. Nat Genet 2001, 29:365-371.
    • (2001) Nat Genet , vol.29 , pp. 365-371
    • Brazma, A.1    Hingamp, P.2    Quackenbush, J.3    Sherlock, G.4    Spellman, P.5    Stoeckert, C.6
  • 7
    • 0034651570 scopus 로고    scopus 로고
    • PC-SPES: a unique inhibitor of proliferation of prostate cancer cells in vitro and in vivo
    • Kubota T., Hisatake J., Hisatake Y., Said J.W., Chen S.S., Holden S., et al. PC-SPES: a unique inhibitor of proliferation of prostate cancer cells in vitro and in vivo. Prostate 2000, 42:163-171.
    • (2000) Prostate , vol.42 , pp. 163-171
    • Kubota, T.1    Hisatake, J.2    Hisatake, Y.3    Said, J.W.4    Chen, S.S.5    Holden, S.6
  • 8
    • 0034330147 scopus 로고    scopus 로고
    • Prospective trial of the herbal supplement PC-SPES in patients with progressive prostate cancer
    • Small E.J., Frohlich M.W., Bok R., Shinohara K., Grossfeld G., Rozenblat Z., et al. Prospective trial of the herbal supplement PC-SPES in patients with progressive prostate cancer. J Clin Oncol 2000, 18:3595-3603.
    • (2000) J Clin Oncol , vol.18 , pp. 3595-3603
    • Small, E.J.1    Frohlich, M.W.2    Bok, R.3    Shinohara, K.4    Grossfeld, G.5    Rozenblat, Z.6
  • 9
    • 79851510937 scopus 로고    scopus 로고
    • Herbal therapy use by cancer patients: a literature review on case reports
    • Olaku O., White J.D. Herbal therapy use by cancer patients: a literature review on case reports. Eur J Cancer 2011, 47(4):508-514.
    • (2011) Eur J Cancer , vol.47 , Issue.4 , pp. 508-514
    • Olaku, O.1    White, J.D.2
  • 10
    • 0037099609 scopus 로고    scopus 로고
    • Molecular effects of the herbal compound PC-SPES: identification of activity pathways in prostate carcinoma
    • Bonham M., Arnold H., Montgomery B., Nelson P.S. Molecular effects of the herbal compound PC-SPES: identification of activity pathways in prostate carcinoma. Cancer Res 2002, 62:3920-3924.
    • (2002) Cancer Res , vol.62 , pp. 3920-3924
    • Bonham, M.1    Arnold, H.2    Montgomery, B.3    Nelson, P.S.4
  • 11
    • 0043269370 scopus 로고    scopus 로고
    • The ameliorating effects of acute and chronic administration of LiuWei Dihuang Wang on learning performance in rodents
    • Hsieh M.T., Cheng S.J., Lin L.W., Wang W.H., Wu C.R. The ameliorating effects of acute and chronic administration of LiuWei Dihuang Wang on learning performance in rodents. Biol Pharm Bull 2003, 26:156-161.
    • (2003) Biol Pharm Bull , vol.26 , pp. 156-161
    • Hsieh, M.T.1    Cheng, S.J.2    Lin, L.W.3    Wang, W.H.4    Wu, C.R.5
  • 12
    • 21044443584 scopus 로고    scopus 로고
    • Effects of Yukmijihwang-tang derivatives (YMJd), a memory enhancing herbal extract, on the gene-expression profile in the rat hippocampus
    • Rho S., Kang M., Choi B., Sim D., Lee J., Lee E., et al. Effects of Yukmijihwang-tang derivatives (YMJd), a memory enhancing herbal extract, on the gene-expression profile in the rat hippocampus. Biol Pharm Bull 2005, 28:87-93.
    • (2005) Biol Pharm Bull , vol.28 , pp. 87-93
    • Rho, S.1    Kang, M.2    Choi, B.3    Sim, D.4    Lee, J.5    Lee, E.6
  • 13
    • 77349121166 scopus 로고    scopus 로고
    • Genome wide expression analysis of the effect of Pinelliae Rhizoma extract on psychological stress
    • Kim B.Y., Cho S.J., Kim H.W., Kim S.Y., Lim S.H., Kim K.O., et al. Genome wide expression analysis of the effect of Pinelliae Rhizoma extract on psychological stress. Phytother Res 2010, 24:384-392.
    • (2010) Phytother Res , vol.24 , pp. 384-392
    • Kim, B.Y.1    Cho, S.J.2    Kim, H.W.3    Kim, S.Y.4    Lim, S.H.5    Kim, K.O.6
  • 14
    • 0018816767 scopus 로고
    • Turmeric: chemistry, technology and quality
    • Govindarajan V.S. Turmeric: chemistry, technology and quality. Crit Rev Food Sci Nutr 1980, 12:199-301.
    • (1980) Crit Rev Food Sci Nutr , vol.12 , pp. 199-301
    • Govindarajan, V.S.1
  • 15
    • 0023790908 scopus 로고
    • Inhibitory effect of curcumin, chlorogenic acid and ferulic acid on tumor promotion in mouse skin by 12-O-tetradecanoylphorbol-13-acetate
    • Huang M.T., Smart R.C., Wong C.Q., Conney A.H. Inhibitory effect of curcumin, chlorogenic acid and ferulic acid on tumor promotion in mouse skin by 12-O-tetradecanoylphorbol-13-acetate. Cancer Res 1988, 48:5941-5946.
    • (1988) Cancer Res , vol.48 , pp. 5941-5946
    • Huang, M.T.1    Smart, R.C.2    Wong, C.Q.3    Conney, A.H.4
  • 16
    • 84856858059 scopus 로고    scopus 로고
    • Anti-carcinogenic action of curcumin by activation of antioxidant defence system and inhibition of NF-κB signalling in lymphoma-bearing mice
    • Das L., Vinayak M. Anti-carcinogenic action of curcumin by activation of antioxidant defence system and inhibition of NF-κB signalling in lymphoma-bearing mice. Biosci Rep 2012, 32:161-170.
    • (2012) Biosci Rep , vol.32 , pp. 161-170
    • Das, L.1    Vinayak, M.2
  • 17
    • 9144231812 scopus 로고    scopus 로고
    • Anti-invasive gene expression profile of curcumin in lung adenocarcinoma based on a high throughput microarray analysis
    • Chen H.W., Yu S.L., Chen J.J.W., Li H.N., Lin Y.C., Yao P.L., et al. Anti-invasive gene expression profile of curcumin in lung adenocarcinoma based on a high throughput microarray analysis. Mol Pharmacol 2004, 65:99-110.
    • (2004) Mol Pharmacol , vol.65 , pp. 99-110
    • Chen, H.W.1    Yu, S.L.2    Chen, J.J.W.3    Li, H.N.4    Lin, Y.C.5    Yao, P.L.6
  • 18
    • 64049117979 scopus 로고    scopus 로고
    • Increased risks of chronic kidney disease associated with prescribed Chinese herbal products suspected to contain aristolochic acid
    • Lai M.N., Lai J.N., Chen P.C., Tseng W.L., Chen Y.Y., Hwang J.S., et al. Increased risks of chronic kidney disease associated with prescribed Chinese herbal products suspected to contain aristolochic acid. Nephrology 2009, 14:227-234.
    • (2009) Nephrology , vol.14 , pp. 227-234
    • Lai, M.N.1    Lai, J.N.2    Chen, P.C.3    Tseng, W.L.4    Chen, Y.Y.5    Hwang, J.S.6
  • 19
    • 77951702257 scopus 로고    scopus 로고
    • Chronic kidney disease and cancer: a troubling connection
    • Stengel B. Chronic kidney disease and cancer: a troubling connection. J Nephrol 2010, 23(3):253-262.
    • (2010) J Nephrol , vol.23 , Issue.3 , pp. 253-262
    • Stengel, B.1
  • 20
    • 75449084985 scopus 로고    scopus 로고
    • Ochratoxin A and aristolochic acid involvement in nephropathies and associated urothelial tract tumours
    • Pfohl-Leszkowicz A. Ochratoxin A and aristolochic acid involvement in nephropathies and associated urothelial tract tumours. Arh Hig Rada Toksikol 2009, 60(4):465-483.
    • (2009) Arh Hig Rada Toksikol , vol.60 , Issue.4 , pp. 465-483
    • Pfohl-Leszkowicz, A.1
  • 21
    • 76949108679 scopus 로고    scopus 로고
    • Microarray analysis reveals the inhibition of nuclear factor-κB signaling by aristolochic acid in normal human kidney (HK-2) cells
    • Chen Y.Y., Chiang S.Y., Wu H.C., Kao S.T., Hsiang C.Y., Ho T.Y., et al. Microarray analysis reveals the inhibition of nuclear factor-κB signaling by aristolochic acid in normal human kidney (HK-2) cells. Acta Pharmacol Sin 2010, 31:227-236.
    • (2010) Acta Pharmacol Sin , vol.31 , pp. 227-236
    • Chen, Y.Y.1    Chiang, S.Y.2    Wu, H.C.3    Kao, S.T.4    Hsiang, C.Y.5    Ho, T.Y.6
  • 22
    • 52049086698 scopus 로고    scopus 로고
    • Relationship between San-Huang-Xie-Xin-Tang and its herbal components on the gene expression profiles in HepG2 cells
    • Cheng W.Y., Wu S.L., Hsiang C.Y., Li C.C., Lai T.Y., Lo H.Y., et al. Relationship between San-Huang-Xie-Xin-Tang and its herbal components on the gene expression profiles in HepG2 cells. Am J Chin Med 2008, 36:783-797.
    • (2008) Am J Chin Med , vol.36 , pp. 783-797
    • Cheng, W.Y.1    Wu, S.L.2    Hsiang, C.Y.3    Li, C.C.4    Lai, T.Y.5    Lo, H.Y.6
  • 23
    • 33646028804 scopus 로고    scopus 로고
    • Molecular targets of dietary agents for prevention and therapy of cancer
    • Aggarwal B.B., Shishodia S. Molecular targets of dietary agents for prevention and therapy of cancer. Biochem Pharmacol 2006, 71:1397-1421.
    • (2006) Biochem Pharmacol , vol.71 , pp. 1397-1421
    • Aggarwal, B.B.1    Shishodia, S.2
  • 25
    • 70350139869 scopus 로고    scopus 로고
    • Comprehensive evaluation of a novel nuclear factor-κB inhibitor, quinoclamine, by transcriptomic analysis
    • Cheng W.Y., Lien J.C., Hsiang C.Y., Wu S.L., Li C.C., Lo H.Y., et al. Comprehensive evaluation of a novel nuclear factor-κB inhibitor, quinoclamine, by transcriptomic analysis. Br J Pharmacol 2009, 157:746-756.
    • (2009) Br J Pharmacol , vol.157 , pp. 746-756
    • Cheng, W.Y.1    Lien, J.C.2    Hsiang, C.Y.3    Wu, S.L.4    Li, C.C.5    Lo, H.Y.6
  • 27
    • 36248964175 scopus 로고    scopus 로고
    • Microarray analysis of vanillin-regulated gene expression profile in human hepatocarcinoma cells
    • Cheng W.Y., Hsiang C.Y., Bau D.T., Chen J.C., Shen W.S., Li C.C., et al. Microarray analysis of vanillin-regulated gene expression profile in human hepatocarcinoma cells. Pharmacol Res 2007, 56:474-482.
    • (2007) Pharmacol Res , vol.56 , pp. 474-482
    • Cheng, W.Y.1    Hsiang, C.Y.2    Bau, D.T.3    Chen, J.C.4    Shen, W.S.5    Li, C.C.6
  • 28
    • 58849158423 scopus 로고    scopus 로고
    • Vanillin inhibits matrix metalloproteinase-9 expression through down-regulation of nuclear factor-κB signaling pathway in human hepatocellular carcinoma cells
    • Liang J.A., Wu S.L., Lo H.Y., Hsiang C.Y., Ho T.Y. Vanillin inhibits matrix metalloproteinase-9 expression through down-regulation of nuclear factor-κB signaling pathway in human hepatocellular carcinoma cells. Mol Pharmacol 2009, 75:151-157.
    • (2009) Mol Pharmacol , vol.75 , pp. 151-157
    • Liang, J.A.1    Wu, S.L.2    Lo, H.Y.3    Hsiang, C.Y.4    Ho, T.Y.5
  • 29
    • 33947317378 scopus 로고    scopus 로고
    • Gene expression profiles distinguish the carcinogenic effects of aristolochic acid in target (kidney) and non-target (liver) tissues in rats
    • S20
    • Chen T., Guo L., Zhang L., Shi L., Fang H., Sun Y., et al. Gene expression profiles distinguish the carcinogenic effects of aristolochic acid in target (kidney) and non-target (liver) tissues in rats. BMC Bioinformatics 2006, 7. S20.
    • (2006) BMC Bioinformatics , vol.7
    • Chen, T.1    Guo, L.2    Zhang, L.3    Shi, L.4    Fang, H.5    Sun, Y.6
  • 31
    • 84856609251 scopus 로고    scopus 로고
    • Experimental evidence of Ginkgo biloba extract EGB as a neuroprotective agent in ischemia stroke rats
    • Zhang Z., Peng D., Zhu H., Wang X. Experimental evidence of Ginkgo biloba extract EGB as a neuroprotective agent in ischemia stroke rats. Brain Res Bull 2012, 87:193-198.
    • (2012) Brain Res Bull , vol.87 , pp. 193-198
    • Zhang, Z.1    Peng, D.2    Zhu, H.3    Wang, X.4
  • 32
    • 64249131014 scopus 로고    scopus 로고
    • Transcriptomic analysis of EGb 761-regulated neuroactive receptor pathway in vivo
    • Su S.Y., Hsieh C.L., Wu S.L., Cheng W.Y., Li C.C., Lo H.Y., et al. Transcriptomic analysis of EGb 761-regulated neuroactive receptor pathway in vivo. J Ethnopharmacol 2009, 123:68-73.
    • (2009) J Ethnopharmacol , vol.123 , pp. 68-73
    • Su, S.Y.1    Hsieh, C.L.2    Wu, S.L.3    Cheng, W.Y.4    Li, C.C.5    Lo, H.Y.6
  • 33
    • 0035892305 scopus 로고    scopus 로고
    • Gene expression microarray analysis in cancer biology, pharmacology, and drug development: progress and potential
    • Clarke P.A., te Poele R., Wooster R., Workman P. Gene expression microarray analysis in cancer biology, pharmacology, and drug development: progress and potential. Biochem Pharmacol 2001, 62:1311-1336.
    • (2001) Biochem Pharmacol , vol.62 , pp. 1311-1336
    • Clarke, P.A.1    te Poele, R.2    Wooster, R.3    Workman, P.4
  • 34
    • 21744436757 scopus 로고    scopus 로고
    • New approaches to mechanism analysis for drug discovery using DNA microarray data combined with KeyMolnet
    • Sato H., Ishida S., Toda K., Matsuda R., Hayashi Y., Shigetaka M., et al. New approaches to mechanism analysis for drug discovery using DNA microarray data combined with KeyMolnet. Curr Drug Discov Technol 2005, 2:89-98.
    • (2005) Curr Drug Discov Technol , vol.2 , pp. 89-98
    • Sato, H.1    Ishida, S.2    Toda, K.3    Matsuda, R.4    Hayashi, Y.5    Shigetaka, M.6
  • 35
    • 33744513688 scopus 로고    scopus 로고
    • Microarray analysis in drug discovery and clinical applications
    • Wang S., Cheng Q. Microarray analysis in drug discovery and clinical applications. Methods Mol Biol 2006, 316:49-65.
    • (2006) Methods Mol Biol , vol.316 , pp. 49-65
    • Wang, S.1    Cheng, Q.2
  • 36
    • 42449143096 scopus 로고    scopus 로고
    • Microarray: an approach for current drug targets
    • Gomase V.S., Tagore S., Kale K.V. Microarray: an approach for current drug targets. Curr Drug Metab 2008, 9:221-231.
    • (2008) Curr Drug Metab , vol.9 , pp. 221-231
    • Gomase, V.S.1    Tagore, S.2    Kale, K.V.3
  • 37
    • 0035213686 scopus 로고    scopus 로고
    • Identification of toxicologically predictive gene sets using cDNA microarrays
    • Thomas R.S., Rank D.R., Penn S.G., Zastrow G.M., Hayes K.R., Pande K., et al. Identification of toxicologically predictive gene sets using cDNA microarrays. Mol Pharmacol 2001, 60:1189-1194.
    • (2001) Mol Pharmacol , vol.60 , pp. 1189-1194
    • Thomas, R.S.1    Rank, D.R.2    Penn, S.G.3    Zastrow, G.M.4    Hayes, K.R.5    Pande, K.6
  • 38
    • 20944433525 scopus 로고    scopus 로고
    • Development of a large-scale chemogenomics database to improve drug candidate selection and to understand mechanisms of chemical toxicity and action
    • Ganter B., Tugendreich S., Pearson C.I., Ayanoglu E., Baumhueter S., Bostian K.A., et al. Development of a large-scale chemogenomics database to improve drug candidate selection and to understand mechanisms of chemical toxicity and action. J Biotechnol 2005, 119:219-244.
    • (2005) J Biotechnol , vol.119 , pp. 219-244
    • Ganter, B.1    Tugendreich, S.2    Pearson, C.I.3    Ayanoglu, E.4    Baumhueter, S.5    Bostian, K.A.6
  • 39
    • 11244334169 scopus 로고    scopus 로고
    • Microarray analysis in human hepatocytes suggests a mechanism for hepatotoxicity induced by trovafloxacin
    • Liguori M.J., Anderson M.G., Bukofzer S., McKim J., Pregenzer J.F., Retief J., et al. Microarray analysis in human hepatocytes suggests a mechanism for hepatotoxicity induced by trovafloxacin. Hepatology 2005, 41:177-186.
    • (2005) Hepatology , vol.41 , pp. 177-186
    • Liguori, M.J.1    Anderson, M.G.2    Bukofzer, S.3    McKim, J.4    Pregenzer, J.F.5    Retief, J.6
  • 40
    • 0033214657 scopus 로고    scopus 로고
    • Application of complementary DNA microarray technology to carcinogen identification, toxicology, and drug safety evaluation
    • Afshari C.A., Nuwaysir E.F., Barrett J.C. Application of complementary DNA microarray technology to carcinogen identification, toxicology, and drug safety evaluation. Cancer Res 1999, 59:4759-4760.
    • (1999) Cancer Res , vol.59 , pp. 4759-4760
    • Afshari, C.A.1    Nuwaysir, E.F.2    Barrett, J.C.3
  • 41
    • 18144399225 scopus 로고    scopus 로고
    • Systems biology in drug safety and metabolism: integration of microarray, real-time PCR and enzyme approaches
    • Yengi L.G. Systems biology in drug safety and metabolism: integration of microarray, real-time PCR and enzyme approaches. Pharmacogenomics 2005, 6:185-192.
    • (2005) Pharmacogenomics , vol.6 , pp. 185-192
    • Yengi, L.G.1
  • 43
    • 0034088857 scopus 로고    scopus 로고
    • A gene expression database for the molecular pharmacology of cancer
    • Scherf U., Ross D.T., Waltham M., Smith L.H., Lee J.K., Tanabe L., et al. A gene expression database for the molecular pharmacology of cancer. Nat Genet 2000, 24:236-244.
    • (2000) Nat Genet , vol.24 , pp. 236-244
    • Scherf, U.1    Ross, D.T.2    Waltham, M.3    Smith, L.H.4    Lee, J.K.5    Tanabe, L.6
  • 44
    • 0041421151 scopus 로고    scopus 로고
    • Prediction of clinical drug efficacy by classification of drug-induced genomic expression profiles in vitro
    • Gunther E.C., Stone D.J., Gerwien R.W., Bento P., Heyes M.P. Prediction of clinical drug efficacy by classification of drug-induced genomic expression profiles in vitro. Proc Natl Acad Sci U S A 2003, 100:9608-9613.
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 9608-9613
    • Gunther, E.C.1    Stone, D.J.2    Gerwien, R.W.3    Bento, P.4    Heyes, M.P.5
  • 46
    • 33749335282 scopus 로고    scopus 로고
    • The Connectivity Map: using gene-expression signatures to connect small molecules, genes, and disease
    • Lamb J., Crawford E.D., Peck D., Modell J.W., Blat I.C., Wrobel M.J., et al. The Connectivity Map: using gene-expression signatures to connect small molecules, genes, and disease. Science 2006, 313:1929-1935.
    • (2006) Science , vol.313 , pp. 1929-1935
    • Lamb, J.1    Crawford, E.D.2    Peck, D.3    Modell, J.W.4    Blat, I.C.5    Wrobel, M.J.6
  • 47
    • 77956997886 scopus 로고    scopus 로고
    • Microarrays for personalized genomic medicine
    • Lam C.W., Lau K.C., Tong S.F. Microarrays for personalized genomic medicine. Adv Clin Chem 2010, 52:1-18.
    • (2010) Adv Clin Chem , vol.52 , pp. 1-18
    • Lam, C.W.1    Lau, K.C.2    Tong, S.F.3
  • 48
    • 76749123852 scopus 로고    scopus 로고
    • Application of connectivity mapping in predictive toxicology based on gene-expression similarity
    • Smalley J.L., Gant T.W., Zhang S.D. Application of connectivity mapping in predictive toxicology based on gene-expression similarity. Toxicology 2010, 268:143-146.
    • (2010) Toxicology , vol.268 , pp. 143-146
    • Smalley, J.L.1    Gant, T.W.2    Zhang, S.D.3
  • 49
    • 78049381533 scopus 로고    scopus 로고
    • Application of bioactivity database of Chinese herbal medicine on the therapeutic prediction, drug development, and safety evaluation
    • Cheng H.M., Li C.C., Chen C.Y., Lo H.Y., Cheng W.Y., Lee C.H., et al. Application of bioactivity database of Chinese herbal medicine on the therapeutic prediction, drug development, and safety evaluation. J Ethnopharmacol 2010, 132:429-437.
    • (2010) J Ethnopharmacol , vol.132 , pp. 429-437
    • Cheng, H.M.1    Li, C.C.2    Chen, C.Y.3    Lo, H.Y.4    Cheng, W.Y.5    Lee, C.H.6
  • 50
    • 0242333835 scopus 로고    scopus 로고
    • Normalization of cDNA microarray data
    • Smyth G.K., Speed T. Normalization of cDNA microarray data. Methods 2003, 31:265-273.
    • (2003) Methods , vol.31 , pp. 265-273
    • Smyth, G.K.1    Speed, T.2
  • 52
    • 2942550697 scopus 로고    scopus 로고
    • GOTree Machine (GOTM): a web-based platform for interpreting sets of interesting genes using Gene Ontology hierarchies
    • Zhang B., Schmoyer D., Kirov S., Snoddy J. GOTree Machine (GOTM): a web-based platform for interpreting sets of interesting genes using Gene Ontology hierarchies. BMC Bioinformatics 2004, 5:16-23.
    • (2004) BMC Bioinformatics , vol.5 , pp. 16-23
    • Zhang, B.1    Schmoyer, D.2    Kirov, S.3    Snoddy, J.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.