Inhibition of inflammatory and proliferative responses of human keratinocytes exposed to the sesquiterpene lactones dehydrocostuslactone and costunolide

PLoS ONE

Volumn 9, Issue 9, 2014, Pages

  Scarponi, Claudia ^a   Butturini, Elena ^b   Sestito, Rosanna ^a,c   Madonna, Stefania ^a   Cavani, Andrea ^a   Mariotto, Sofia ^b   Albanesi, Cristina ^a  

^a LABORATORIO DI PATOLOGIA VASCOLARE   (Italy)

^b UNIVERSITY OF VERONA   (Italy)

^c REGINA ELENA NATIONAL CANCER INSTITUTE   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

COSTUNOLIDE; DEHYDROCOSTUSLACTONE; EPIDERMAL GROWTH FACTOR RECEPTOR; GAMMA INTERFERON; GAMMA INTERFERON INDUCIBLE PROTEIN 10; GLUTATHIONE; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 22; JANUS KINASE 1; JANUS KINASE 2; LACTONE DERIVATIVE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MONOCYTE CHEMOTACTIC PROTEIN 1; SESQUITERPENE DERIVATIVE; STAT1 PROTEIN; STAT3 PROTEIN; SUPPRESSOR OF CYTOKINE SIGNALING 3; UNCLASSIFIED DRUG; ANTIINFLAMMATORY AGENT; DEHYDROCOSTUS LACTONE; INTERLEUKIN DERIVATIVE; INTERLEUKIN-22; LACTONE; SESQUITERPENE;

ANTIINFLAMMATORY ACTIVITY; ANTIPROLIFERATIVE ACTIVITY; APOPTOSIS; ARTICLE; CELL CYCLE ARREST; CELL CYCLE PROGRESSION; CONTROLLED STUDY; DRUG EXPOSURE; GENE EXPRESSION; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; HUMAN TISSUE; IN VITRO STUDY; KERATINOCYTE; PROTEIN PHOSPHORYLATION; REAL TIME POLYMERASE CHAIN REACTION; REGULATOR GENE; RNA ISOLATION; SKIN BIOPSY; WESTERN BLOTTING; WOUND HEALING; ANTAGONISTS AND INHIBITORS; CELL CULTURE; CELL CYCLE CHECKPOINT; CELL MOTION; CELL PROLIFERATION; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; INTRACELLULAR SPACE; METABOLISM; PHOSPHORYLATION;

ANTI-INFLAMMATORY AGENTS; APOPTOSIS; CELL CYCLE CHECKPOINTS; CELL MOVEMENT; CELL PROLIFERATION; CELLS, CULTURED; GENE EXPRESSION REGULATION; GLUTATHIONE; HUMANS; INTERFERON-GAMMA; INTERLEUKINS; INTRACELLULAR SPACE; KERATINOCYTES; LACTONES; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; PHOSPHORYLATION; RECEPTOR, EPIDERMAL GROWTH FACTOR; SESQUITERPENES; STAT1 TRANSCRIPTION FACTOR; STAT3 TRANSCRIPTION FACTOR;

EID: 84907153990     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0107904     Document Type: Article

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