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Volumn 25, Issue 6, 2007, Pages 581-588

Resident skin cells in psoriasis: a special look at the pathogenetic functions of keratinocytes

Author keywords

[No Author keywords available]

Indexed keywords

GROWTH FACTOR;

EID: 36048944693     PISSN: 0738081X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.clindermatol.2007.08.013     Document Type: Review
Times cited : (162)

References (75)
  • 1
    • 21644455704 scopus 로고    scopus 로고
    • Psoriasis: dysregulation of innate immunity
    • Bos J.D., de Rie M.A., Teunissen M.B.M., et al. Psoriasis: dysregulation of innate immunity. Br J Dermatol 152 (2005) 1098-1107
    • (2005) Br J Dermatol , vol.152 , pp. 1098-1107
    • Bos, J.D.1    de Rie, M.A.2    Teunissen, M.B.M.3
  • 3
    • 0029861579 scopus 로고    scopus 로고
    • Dermal injection of immunocytes induces psoriasis
    • Wrone-Smith T., and Nickoloff B.J. Dermal injection of immunocytes induces psoriasis. J Clin Invest 98 (1996) 1878-1887
    • (1996) J Clin Invest , vol.98 , pp. 1878-1887
    • Wrone-Smith, T.1    Nickoloff, B.J.2
  • 4
    • 13444269249 scopus 로고    scopus 로고
    • Stat3 links activated keratinocytes and immunocytes required for development of psoriasis in a novel transgenic mouse model
    • Sano S., Chan K.S., Carbajal S., et al. Stat3 links activated keratinocytes and immunocytes required for development of psoriasis in a novel transgenic mouse model. Nat Med 11 (2005) 43-49
    • (2005) Nat Med , vol.11 , pp. 43-49
    • Sano, S.1    Chan, K.S.2    Carbajal, S.3
  • 5
    • 0037142027 scopus 로고    scopus 로고
    • TNF-mediated inflammatory skin disease in mice with epidermis-specific deletion of IKK2
    • Pasparakis M., Courtois G., Hafner M., et al. TNF-mediated inflammatory skin disease in mice with epidermis-specific deletion of IKK2. Nature 417 (2002) 861-866
    • (2002) Nature , vol.417 , pp. 861-866
    • Pasparakis, M.1    Courtois, G.2    Hafner, M.3
  • 6
    • 25144497098 scopus 로고    scopus 로고
    • Psoriasis-like skin disease and arthritis caused by inducible epidermal deletion of Jun proteins
    • Zenz R., Eferl R., Kenner L., et al. Psoriasis-like skin disease and arthritis caused by inducible epidermal deletion of Jun proteins. Nature 437 (2005) 369-375
    • (2005) Nature , vol.437 , pp. 369-375
    • Zenz, R.1    Eferl, R.2    Kenner, L.3
  • 7
    • 0032729645 scopus 로고    scopus 로고
    • The majority of epidermal T cells in psoriasis vulgaris lesions can produce type 1 cytokines, interferon-gamma, interleukin-2, and tumor necrosis factor-alpha, defining TC1 (cytotoxic T lymphocyte) and TH1 effector populations: a type 1 differentiation bias is also measured in circulating blood T cells in psoriatic patients
    • Austin L.M., Ozawa M., Kikuchi T., et al. The majority of epidermal T cells in psoriasis vulgaris lesions can produce type 1 cytokines, interferon-gamma, interleukin-2, and tumor necrosis factor-alpha, defining TC1 (cytotoxic T lymphocyte) and TH1 effector populations: a type 1 differentiation bias is also measured in circulating blood T cells in psoriatic patients. J Invest Dermatol 113 (1999) 752-759
    • (1999) J Invest Dermatol , vol.113 , pp. 752-759
    • Austin, L.M.1    Ozawa, M.2    Kikuchi, T.3
  • 8
    • 0347285359 scopus 로고    scopus 로고
    • Increased expression of interleukin 23 p19 and p40 in lesional skin of patients with psoriasis vulgaris
    • Lee E., Trepicchio W.L., Oestreicher J.L., et al. Increased expression of interleukin 23 p19 and p40 in lesional skin of patients with psoriasis vulgaris. J Exp Med 199 (2004) 125-130
    • (2004) J Exp Med , vol.199 , pp. 125-130
    • Lee, E.1    Trepicchio, W.L.2    Oestreicher, J.L.3
  • 9
    • 8244228677 scopus 로고    scopus 로고
    • Identification of a major susceptibility locus on chromosome 6p and evidence for further disease loci revealed by a two stage genome-wide search in psoriasis
    • Trembath R.C., Clough R.L., Rosbotham J.L., et al. Identification of a major susceptibility locus on chromosome 6p and evidence for further disease loci revealed by a two stage genome-wide search in psoriasis. Hum Mol Genet 6 (1997) 813-820
    • (1997) Hum Mol Genet , vol.6 , pp. 813-820
    • Trembath, R.C.1    Clough, R.L.2    Rosbotham, J.L.3
  • 10
    • 0032806844 scopus 로고    scopus 로고
    • Is an epitope on keratin 17 a major target for autoreactive T lymphocytes in psoriasis?
    • Gudmundsdottir A.S., Sigmundsdottir H., Sigurgeirsson B., et al. Is an epitope on keratin 17 a major target for autoreactive T lymphocytes in psoriasis?. Clin Exp Immunol 117 (1999) 580-586
    • (1999) Clin Exp Immunol , vol.117 , pp. 580-586
    • Gudmundsdottir, A.S.1    Sigmundsdottir, H.2    Sigurgeirsson, B.3
  • 11
    • 3042633817 scopus 로고    scopus 로고
    • Identification of autoantigens in psoriatic plaques using expression cloning
    • Jones D.A., Yawalkar N., Suh Ki.-Y., et al. Identification of autoantigens in psoriatic plaques using expression cloning. J Invest Dermatol 123 (2004) 93-100
    • (2004) J Invest Dermatol , vol.123 , pp. 93-100
    • Jones, D.A.1    Yawalkar, N.2    Suh, Ki.-Y.3
  • 12
    • 0346969831 scopus 로고    scopus 로고
    • Possible involvement of epidermodysplasia verruciformis human papillomaviruses in the immunopathogenesis of psoriasis: a proposed hypothesis
    • Majewski S., and Jablonska S. Possible involvement of epidermodysplasia verruciformis human papillomaviruses in the immunopathogenesis of psoriasis: a proposed hypothesis. Exp Dermatol 12 (2003) 721-728
    • (2003) Exp Dermatol , vol.12 , pp. 721-728
    • Majewski, S.1    Jablonska, S.2
  • 14
    • 30944461598 scopus 로고    scopus 로고
    • CD56brightCD16(-) NK cells accumulate in psoriatic skin in response to CXCL10 and CCL5 and exacerbate skin inflammation
    • Ottaviani C., Nasorri F., Bedini C., et al. CD56brightCD16(-) NK cells accumulate in psoriatic skin in response to CXCL10 and CCL5 and exacerbate skin inflammation. Eur J Immunol 36 (2006) 118-128
    • (2006) Eur J Immunol , vol.36 , pp. 118-128
    • Ottaviani, C.1    Nasorri, F.2    Bedini, C.3
  • 15
    • 0035723611 scopus 로고    scopus 로고
    • Psoriasis vulgaris-a sterile antibacterial skin reaction mediated by cross-reactive T cells? An immunological view of the pathophysiology of psoriasis
    • Prinz J.C. Psoriasis vulgaris-a sterile antibacterial skin reaction mediated by cross-reactive T cells? An immunological view of the pathophysiology of psoriasis. Clin Exp Dermatol 26 (2001) 326-332
    • (2001) Clin Exp Dermatol , vol.26 , pp. 326-332
    • Prinz, J.C.1
  • 16
    • 0027248633 scopus 로고
    • Flow cytometric identification of proliferative subpopulations within normal human epidermis and the localization of the primary hyperproliferative population in psoriasis
    • Bata-Csorgo Z., Hammerberg C., Voorhees J.J., et al. Flow cytometric identification of proliferative subpopulations within normal human epidermis and the localization of the primary hyperproliferative population in psoriasis. J Exp Med 178 (1993) 1271-1281
    • (1993) J Exp Med , vol.178 , pp. 1271-1281
    • Bata-Csorgo, Z.1    Hammerberg, C.2    Voorhees, J.J.3
  • 17
    • 0028927968 scopus 로고
    • Altered keratinocyte growth and differentiation in psoriasis
    • McKay I.A., and Leigh I.M. Altered keratinocyte growth and differentiation in psoriasis. Clin Dermatol 13 (1995) 105-114
    • (1995) Clin Dermatol , vol.13 , pp. 105-114
    • McKay, I.A.1    Leigh, I.M.2
  • 18
    • 2342461732 scopus 로고    scopus 로고
    • Unique keratinization process in psoriasis: late differentiation markers are abolished because of the premature cell death
    • Iizuka H., Takahashi H., Honma M., et al. Unique keratinization process in psoriasis: late differentiation markers are abolished because of the premature cell death. J Dermatol 31 (2004) 271-276
    • (2004) J Dermatol , vol.31 , pp. 271-276
    • Iizuka, H.1    Takahashi, H.2    Honma, M.3
  • 19
  • 20
    • 0031738758 scopus 로고    scopus 로고
    • Autocrine regulation of keratinocytes: the emerging role of heparin-binding, epidermal growth factor-related growth factors
    • Piepkorn M., Pittelkow M.R., and Cook P.W. Autocrine regulation of keratinocytes: the emerging role of heparin-binding, epidermal growth factor-related growth factors. J Invest Dermatol 111 (1998) 715-721
    • (1998) J Invest Dermatol , vol.111 , pp. 715-721
    • Piepkorn, M.1    Pittelkow, M.R.2    Cook, P.W.3
  • 21
    • 0027217314 scopus 로고
    • Loss of expression of transforming growth factor beta in skin and skin tumors is associated with hyperproliferation and a high risk for malignant conversion
    • Glick A.B., Kulkarni A.B., Tennenbaum T., et al. Loss of expression of transforming growth factor beta in skin and skin tumors is associated with hyperproliferation and a high risk for malignant conversion. Proc Natl Acad Sci U S A 90 (1993) 6076-6080
    • (1993) Proc Natl Acad Sci U S A , vol.90 , pp. 6076-6080
    • Glick, A.B.1    Kulkarni, A.B.2    Tennenbaum, T.3
  • 22
    • 0027468283 scopus 로고
    • Targeting expression of keratinocyte growth factor to keratinocytes elicits striking changes in epithelial differentiation in transgenic mice
    • Guo L., Yu Q.C., and Fuchs E. Targeting expression of keratinocyte growth factor to keratinocytes elicits striking changes in epithelial differentiation in transgenic mice. EMBO J 12 (1993) 973-986
    • (1993) EMBO J , vol.12 , pp. 973-986
    • Guo, L.1    Yu, Q.C.2    Fuchs, E.3
  • 23
    • 0025876488 scopus 로고
    • Transgenic mice provide new insights into the role of TGF-α during epidermal development and differentiation
    • Vassar R., and Fuchs E. Transgenic mice provide new insights into the role of TGF-α during epidermal development and differentiation. Genes Dev 5 (1991) 714-727
    • (1991) Genes Dev , vol.5 , pp. 714-727
    • Vassar, R.1    Fuchs, E.2
  • 24
    • 0030664602 scopus 로고    scopus 로고
    • Transgenic expression of the human amphiregulin gene induces a psoriasis-like phenotype
    • Cook P.W., Piepkorn M., Clegg C.H., et al. Transgenic expression of the human amphiregulin gene induces a psoriasis-like phenotype. J Clin Invest 100 (1997) 2286-2294
    • (1997) J Clin Invest , vol.100 , pp. 2286-2294
    • Cook, P.W.1    Piepkorn, M.2    Clegg, C.H.3
  • 25
    • 0029969370 scopus 로고    scopus 로고
    • Keratinocyte growth factor inhibits cross-linked envelope formation and nucleosomal fragmentation in cultured human keratinocytes
    • Hines M.D., and Allen-Hoffmann B.L. Keratinocyte growth factor inhibits cross-linked envelope formation and nucleosomal fragmentation in cultured human keratinocytes. J Biol Chem 271 (1996) 6245-6251
    • (1996) J Biol Chem , vol.271 , pp. 6245-6251
    • Hines, M.D.1    Allen-Hoffmann, B.L.2
  • 26
    • 20244382424 scopus 로고    scopus 로고
    • Amphiregulin is required to maintain the psoriatic phenotype of human skin grafts on severe combined immunodeficient mice
    • Bhagavathula N., Nerusu K.C., Fisher G.J., et al. Amphiregulin is required to maintain the psoriatic phenotype of human skin grafts on severe combined immunodeficient mice. Am J Pathol 166 (2005) 1009-1016
    • (2005) Am J Pathol , vol.166 , pp. 1009-1016
    • Bhagavathula, N.1    Nerusu, K.C.2    Fisher, G.J.3
  • 27
    • 0025328916 scopus 로고
    • Transforming growth factor-beta 1 localization in normal and psoriatic epidermal keratinocytes in situ
    • Kane C.J., Knapp A.M., Mansbridge J.N., et al. Transforming growth factor-beta 1 localization in normal and psoriatic epidermal keratinocytes in situ. J Cell Physiol 144 (1990) 144-150
    • (1990) J Cell Physiol , vol.144 , pp. 144-150
    • Kane, C.J.1    Knapp, A.M.2    Mansbridge, J.N.3
  • 28
    • 0141758371 scopus 로고    scopus 로고
    • Downregulation of TGFbeta isoforms and their receptors contributes to keratinocyte hyperproliferation in psoriasis vulgaris
    • Doi H., Shibata M.A., Kiyokane K., et al. Downregulation of TGFbeta isoforms and their receptors contributes to keratinocyte hyperproliferation in psoriasis vulgaris. J Dermatol Sci 33 (2003) 7-16
    • (2003) J Dermatol Sci , vol.33 , pp. 7-16
    • Doi, H.1    Shibata, M.A.2    Kiyokane, K.3
  • 29
    • 2442548490 scopus 로고    scopus 로고
    • Latent TGFbeta1 overexpression in keratinocytes results in a severe psoriasis-like skin disorder
    • Li A.G., Wang D., Feng X.H., et al. Latent TGFbeta1 overexpression in keratinocytes results in a severe psoriasis-like skin disorder. EMBO J 23 (2004) 1770-1781
    • (2004) EMBO J , vol.23 , pp. 1770-1781
    • Li, A.G.1    Wang, D.2    Feng, X.H.3
  • 30
    • 0343019918 scopus 로고
    • Interleukin 6 is expressed in high levels in psoriatic skin and stimulates proliferation of cultured human keratinocytes
    • Grossman R.M., Krueger J., Yourish D., et al. Interleukin 6 is expressed in high levels in psoriatic skin and stimulates proliferation of cultured human keratinocytes. Proc Natl Acad Sci 86 (1989) 6367-6371
    • (1989) Proc Natl Acad Sci , vol.86 , pp. 6367-6371
    • Grossman, R.M.1    Krueger, J.2    Yourish, D.3
  • 31
    • 27544481752 scopus 로고    scopus 로고
    • The dynamics of gene expression of interleukin-19 and interleukin-20 and their receptors in psoriasis
    • Otkjaer K., Kragballe K., Funding A.T., et al. The dynamics of gene expression of interleukin-19 and interleukin-20 and their receptors in psoriasis. Br J Dermatol 153 (2005) 911-918
    • (2005) Br J Dermatol , vol.153 , pp. 911-918
    • Otkjaer, K.1    Kragballe, K.2    Funding, A.T.3
  • 32
    • 11044228418 scopus 로고    scopus 로고
    • Combined haplotype analysis of the interleukin-19 and -20 genes: relationship to plaque-type psoriasis
    • Koks S., Kingo K., Ratsep R., et al. Combined haplotype analysis of the interleukin-19 and -20 genes: relationship to plaque-type psoriasis. Genes Immun 5 (2004) 662-667
    • (2004) Genes Immun , vol.5 , pp. 662-667
    • Koks, S.1    Kingo, K.2    Ratsep, R.3
  • 33
    • 0028842377 scopus 로고
    • Kinetics and regulation of human keratinocyte stem cell growth in short-term primary ex vivo culture. Cooperative growth factors from psoriatic lesional T lymphocytes stimulate proliferation among psoriatic uninvolved, but not normal, stem keratinocytes
    • Bata-Csorgo Z., Hammerberg C., Voorhees J.J., et al. Kinetics and regulation of human keratinocyte stem cell growth in short-term primary ex vivo culture. Cooperative growth factors from psoriatic lesional T lymphocytes stimulate proliferation among psoriatic uninvolved, but not normal, stem keratinocytes. J Clin Invest 95 (1995) 317-327
    • (1995) J Clin Invest , vol.95 , pp. 317-327
    • Bata-Csorgo, Z.1    Hammerberg, C.2    Voorhees, J.J.3
  • 34
    • 0025261752 scopus 로고
    • Psoriasis induced at the injection site of recombinant interferon gamma. Results of immunohistologic investigations
    • Fierlbeck G., Rassner G., and Müller C. Psoriasis induced at the injection site of recombinant interferon gamma. Results of immunohistologic investigations. Arch Dermatol 126 (1990) 351-355
    • (1990) Arch Dermatol , vol.126 , pp. 351-355
    • Fierlbeck, G.1    Rassner, G.2    Müller, C.3
  • 35
    • 0033043804 scopus 로고    scopus 로고
    • Psoriatic keratinocytes show reduced IRF-1 and STAT-1α activation in response to gamma-IFN
    • Jackson M., Howie S.E., Weller R., et al. Psoriatic keratinocytes show reduced IRF-1 and STAT-1α activation in response to gamma-IFN. FASEB J 13 (1999) 495-502
    • (1999) FASEB J , vol.13 , pp. 495-502
    • Jackson, M.1    Howie, S.E.2    Weller, R.3
  • 36
    • 0034052290 scopus 로고    scopus 로고
    • Response of keratinocytes from normal and psoriatic epidermis to interferon-gamma differs in the expression of zinc-alpha (2)-glycoprotein and cathepsin D
    • Chen S.H., Arany I., Apisarnthanarax N., et al. Response of keratinocytes from normal and psoriatic epidermis to interferon-gamma differs in the expression of zinc-alpha (2)-glycoprotein and cathepsin D. FASEB J 14 (2000) 565-571
    • (2000) FASEB J , vol.14 , pp. 565-571
    • Chen, S.H.1    Arany, I.2    Apisarnthanarax, N.3
  • 37
    • 0026556699 scopus 로고
    • Expression of interferon-gamma receptors in normal and psoriatic skin
    • Scheynius A., Fransson J., Johansson C., et al. Expression of interferon-gamma receptors in normal and psoriatic skin. J Invest Dermatol 98 (1992) 255-258
    • (1992) J Invest Dermatol , vol.98 , pp. 255-258
    • Scheynius, A.1    Fransson, J.2    Johansson, C.3
  • 38
    • 0347624709 scopus 로고    scopus 로고
    • HCR, a candidate gene for psoriasis, is expressed differently in psoriasis and other hyperproliferative skin disorders and is downregulated by interferon-gamma in keratinocytes
    • Suomela S., Elomaa O., Asumalahti K., et al. HCR, a candidate gene for psoriasis, is expressed differently in psoriasis and other hyperproliferative skin disorders and is downregulated by interferon-gamma in keratinocytes. J Invest Dermatol 121 (2003) 1360-1364
    • (2003) J Invest Dermatol , vol.121 , pp. 1360-1364
    • Suomela, S.1    Elomaa, O.2    Asumalahti, K.3
  • 39
    • 0032939560 scopus 로고    scopus 로고
    • IL-17 is produced by nickel-specific T lymphocytes and regulates ICAM-1 expression and chemokine production in human keratinocytes: synergistic or antagonist effects with IFN-gamma and TNF-alpha
    • Albanesi C., Cavani A., and Girolomoni G. IL-17 is produced by nickel-specific T lymphocytes and regulates ICAM-1 expression and chemokine production in human keratinocytes: synergistic or antagonist effects with IFN-gamma and TNF-alpha. J Immunol 162 (1999) 494-502
    • (1999) J Immunol , vol.162 , pp. 494-502
    • Albanesi, C.1    Cavani, A.2    Girolomoni, G.3
  • 40
    • 18044399978 scopus 로고    scopus 로고
    • Psoriasis: the plot thickens...
    • Schön M.P., and Ruzicka T. Psoriasis: the plot thickens.... Nat Immunol 2 (2001) 91
    • (2001) Nat Immunol , vol.2 , pp. 91
    • Schön, M.P.1    Ruzicka, T.2
  • 41
    • 43949158868 scopus 로고
    • Immunological functions of non-professional antigen-presenting cells: new insights from studies of T-cell interactions with keratinocytes
    • Nickoloff B.J., and Turka L.A. Immunological functions of non-professional antigen-presenting cells: new insights from studies of T-cell interactions with keratinocytes. Immuno Today 15 (1994) 464-469
    • (1994) Immuno Today , vol.15 , pp. 464-469
    • Nickoloff, B.J.1    Turka, L.A.2
  • 42
    • 0027305254 scopus 로고
    • MCP-1 mRNA expression in basal keratinocytes of psoriatic lesions
    • Gillitzer R., Wolff K., Tong D., et al. MCP-1 mRNA expression in basal keratinocytes of psoriatic lesions. J Invest Dermatol 101 (1993) 127-131
    • (1993) J Invest Dermatol , vol.101 , pp. 127-131
    • Gillitzer, R.1    Wolff, K.2    Tong, D.3
  • 43
    • 0023792898 scopus 로고    scopus 로고
    • Detection of a gamma interferon-induced protein IP-10 in psoriatic plaques
    • Gottlieb A.B., Luster A.D., Posnett D.N., et al. Detection of a gamma interferon-induced protein IP-10 in psoriatic plaques. J Exp Med 168 (1998) 941-948
    • (1998) J Exp Med , vol.168 , pp. 941-948
    • Gottlieb, A.B.1    Luster, A.D.2    Posnett, D.N.3
  • 44
    • 0034605067 scopus 로고    scopus 로고
    • Macrophage inflammatory protein 3alpha is expressed at inflamed epithelial surfaces and is the most potent chemokine known in attracting Langerhans cell precursors
    • Dieu-Nosjan M.C., Massacrier C., Homey B., et al. Macrophage inflammatory protein 3alpha is expressed at inflamed epithelial surfaces and is the most potent chemokine known in attracting Langerhans cell precursors. J Exp Med 192 (2000) 705-718
    • (2000) J Exp Med , vol.192 , pp. 705-718
    • Dieu-Nosjan, M.C.1    Massacrier, C.2    Homey, B.3
  • 45
    • 0034176108 scopus 로고    scopus 로고
    • Cutting edge: the orphan chemokine receptor G protein-coupled receptor-2 (GPR-2, CCR10) binds the skin-associated chemokine CCL27 (CTACK/ALP/ILC)
    • Homey B., Wang W., Soto H., et al. Cutting edge: the orphan chemokine receptor G protein-coupled receptor-2 (GPR-2, CCR10) binds the skin-associated chemokine CCL27 (CTACK/ALP/ILC). J Immunol 164 (2000) 3465-3470
    • (2000) J Immunol , vol.164 , pp. 3465-3470
    • Homey, B.1    Wang, W.2    Soto, H.3
  • 46
    • 0036150006 scopus 로고    scopus 로고
    • Sequential involvement of CCR2 and CCR6 ligands for immature dendritic cell recruitment: possible role at inflamed epithelial surfaces
    • Vanbervliet B., Homey B., Durand I., et al. Sequential involvement of CCR2 and CCR6 ligands for immature dendritic cell recruitment: possible role at inflamed epithelial surfaces. Eur J Immunol 32 (2002) 231-242
    • (2002) Eur J Immunol , vol.32 , pp. 231-242
    • Vanbervliet, B.1    Homey, B.2    Durand, I.3
  • 47
    • 0036170945 scopus 로고    scopus 로고
    • CCL27-CCR10 interactions regulate T cell-mediated skin inflammation
    • Homey B., Alenius H., Müller A., et al. CCL27-CCR10 interactions regulate T cell-mediated skin inflammation. Nat Med 8 (2002) 157-165
    • (2002) Nat Med , vol.8 , pp. 157-165
    • Homey, B.1    Alenius, H.2    Müller, A.3
  • 48
    • 0036681542 scopus 로고    scopus 로고
    • Immune surveillance and effector functions of CCR10(+) skin homing T cells
    • Hudak S., Hagen M., Liu Y., et al. Immune surveillance and effector functions of CCR10(+) skin homing T cells. J Immunol 169 (2002) 1189-1196
    • (2002) J Immunol , vol.169 , pp. 1189-1196
    • Hudak, S.1    Hagen, M.2    Liu, Y.3
  • 49
    • 0346995201 scopus 로고    scopus 로고
    • Distinct patterns of gene expression in the skin lesions of atopic dermatitis and psoriasis: a gene microarray analysis
    • Nomura I., Gao B., Boguniewicz, et al. Distinct patterns of gene expression in the skin lesions of atopic dermatitis and psoriasis: a gene microarray analysis. J Allergy Clin Immunol 112 (2003) 1195-1202
    • (2003) J Allergy Clin Immunol , vol.112 , pp. 1195-1202
    • Nomura, I.1    Gao, B.2    Boguniewicz3
  • 50
    • 0036792569 scopus 로고    scopus 로고
    • Nitric oxide donors suppress chemokine production by keratinocytes in vitro and in vivo
    • Giustizieri M.L., Albanesi C., Scarponi C., et al. Nitric oxide donors suppress chemokine production by keratinocytes in vitro and in vivo. Am J Pathol 161 (2002) 1409-1418
    • (2002) Am J Pathol , vol.161 , pp. 1409-1418
    • Giustizieri, M.L.1    Albanesi, C.2    Scarponi, C.3
  • 51
    • 0037223634 scopus 로고    scopus 로고
    • Arginase 1 overexpression in psoriasis: limitation of inducible nitric oxide synthase activity as a molecular mechanism for keratinocyte hyperproliferation
    • Bruch-Gerharz D., Schnorr O., Suschek C., et al. Arginase 1 overexpression in psoriasis: limitation of inducible nitric oxide synthase activity as a molecular mechanism for keratinocyte hyperproliferation. Am J Pathol 162 (2003) 203-211
    • (2003) Am J Pathol , vol.162 , pp. 203-211
    • Bruch-Gerharz, D.1    Schnorr, O.2    Suschek, C.3
  • 52
    • 0345275923 scopus 로고    scopus 로고
    • Explaining decreased nitric oxide production in psoriatic lesions: arginase 1 overexpression versus calcitonin gene-related peptide
    • Namazi M.R. Explaining decreased nitric oxide production in psoriatic lesions: arginase 1 overexpression versus calcitonin gene-related peptide. Am J Pathol 163 (2003) 2642-2643
    • (2003) Am J Pathol , vol.163 , pp. 2642-2643
    • Namazi, M.R.1
  • 53
    • 3042644435 scopus 로고    scopus 로고
    • Interleukin-10: an important immunoregulatory cytokine with major impact on psoriasis
    • Asadullah K., Sabat R., Friedrich M., et al. Interleukin-10: an important immunoregulatory cytokine with major impact on psoriasis. Curr Drug Targets Inflamm Allergy 3 (2004) 185-192
    • (2004) Curr Drug Targets Inflamm Allergy , vol.3 , pp. 185-192
    • Asadullah, K.1    Sabat, R.2    Friedrich, M.3
  • 54
    • 11844304978 scopus 로고    scopus 로고
    • Dimethylfumarate for psoriasis: more than a dietary curiosity
    • Mrowietz U., and Asadullah K. Dimethylfumarate for psoriasis: more than a dietary curiosity. Trends Mol Med 11 (2005) 43-48
    • (2005) Trends Mol Med , vol.11 , pp. 43-48
    • Mrowietz, U.1    Asadullah, K.2
  • 55
    • 0035113406 scopus 로고    scopus 로고
    • Response of psoriasis to interleukin-10 is associated with suppression of cutaneous type 1 inflammation, down-regulation of the epidermal interleukin-8/CXCR2 pathway and normalization of keratinocyte maturation
    • Reich K., Garbe C., Blaschke V., et al. Response of psoriasis to interleukin-10 is associated with suppression of cutaneous type 1 inflammation, down-regulation of the epidermal interleukin-8/CXCR2 pathway and normalization of keratinocyte maturation. J Invest Dermatol 116 (2001) 319-329
    • (2001) J Invest Dermatol , vol.116 , pp. 319-329
    • Reich, K.1    Garbe, C.2    Blaschke, V.3
  • 56
    • 0035725785 scopus 로고    scopus 로고
    • The antipsoriatic drug dimethylfumarate strongly suppresses chemokine production in human keratinocytes and peripheral blood mononuclear cells
    • Stoof T.J., Flier J., Sampat S., et al. The antipsoriatic drug dimethylfumarate strongly suppresses chemokine production in human keratinocytes and peripheral blood mononuclear cells. Br J Dermatol 144 (2001) 1114-1120
    • (2001) Br J Dermatol , vol.144 , pp. 1114-1120
    • Stoof, T.J.1    Flier, J.2    Sampat, S.3
  • 57
    • 0029120452 scopus 로고
    • The interleukin-1 axis and cutaneous inflammation
    • Kupper T.S., and Groves R.W. The interleukin-1 axis and cutaneous inflammation. J Invest Dermatol 105 (1995) 62S-66S
    • (1995) J Invest Dermatol , vol.105
    • Kupper, T.S.1    Groves, R.W.2
  • 58
    • 0027996250 scopus 로고
    • Detection of interleukin-1 receptors in human epidermis. Induction of the type II receptor after organ culture and in psoriasis
    • Groves R.W., Sherman L., Mizutani H., et al. Detection of interleukin-1 receptors in human epidermis. Induction of the type II receptor after organ culture and in psoriasis. Am J Pathol 145 (1994) 1048-1056
    • (1994) Am J Pathol , vol.145 , pp. 1048-1056
    • Groves, R.W.1    Sherman, L.2    Mizutani, H.3
  • 59
    • 0030016946 scopus 로고    scopus 로고
    • Inflammatory and hyperproliferative skin disease in mice that express elevated levels of the IL-1 receptor (type I) on epidermal keratinocytes. Evidence that IL-1-inducible secondary cytokines produced by keratinocytes in vivo can cause skin disease
    • Groves R.W., Rauschmayr T., Nakamura K., et al. Inflammatory and hyperproliferative skin disease in mice that express elevated levels of the IL-1 receptor (type I) on epidermal keratinocytes. Evidence that IL-1-inducible secondary cytokines produced by keratinocytes in vivo can cause skin disease. J Clin Invest 98 (1996) 336-344
    • (1996) J Clin Invest , vol.98 , pp. 336-344
    • Groves, R.W.1    Rauschmayr, T.2    Nakamura, K.3
  • 60
    • 0034663951 scopus 로고    scopus 로고
    • Inhibition of keratinocyte apoptosis by IL-15: a new parameter in the pathogenesis of psoriasis?
    • Rückert R., Asadullah K., Seifert M., et al. Inhibition of keratinocyte apoptosis by IL-15: a new parameter in the pathogenesis of psoriasis?. J Immunol 165 (2000) 2240-2250
    • (2000) J Immunol , vol.165 , pp. 2240-2250
    • Rückert, R.1    Asadullah, K.2    Seifert, M.3
  • 61
    • 0042835808 scopus 로고    scopus 로고
    • Exacerbated and prolonged allergic and non-allergic inflammatory cutaneous reaction in mice with targeted interleukin-18 expression in the skin
    • Kawase Y., Hoshino T., Yokota K., et al. Exacerbated and prolonged allergic and non-allergic inflammatory cutaneous reaction in mice with targeted interleukin-18 expression in the skin. J Invest Dermatol 121 (2003) 502-509
    • (2003) J Invest Dermatol , vol.121 , pp. 502-509
    • Kawase, Y.1    Hoshino, T.2    Yokota, K.3
  • 62
    • 0027980960 scopus 로고
    • Overexpression of vascular permeability factor/vascular endothelial growth factor and its receptors in psoriasis
    • Detmar M., Brown L.F., Claffey K.P., et al. Overexpression of vascular permeability factor/vascular endothelial growth factor and its receptors in psoriasis. J Exp Med 180 (1994) 1141-1146
    • (1994) J Exp Med , vol.180 , pp. 1141-1146
    • Detmar, M.1    Brown, L.F.2    Claffey, K.P.3
  • 63
    • 0035312832 scopus 로고    scopus 로고
    • Paracrine regulation of keratinocyte proliferation and differentiation
    • Werner S., and Smola H. Paracrine regulation of keratinocyte proliferation and differentiation. Trends Cell Biol 11 (2001) 143-146
    • (2001) Trends Cell Biol , vol.11 , pp. 143-146
    • Werner, S.1    Smola, H.2
  • 64
    • 0032768526 scopus 로고    scopus 로고
    • Keratinocyte growth regulation in fibroblast coculture via a double paracrine mechanism
    • Maas-Szabowski N., Shimotoyodome A., and Fusenig N.E. Keratinocyte growth regulation in fibroblast coculture via a double paracrine mechanism. J Cell Sci 112 (1999) 1843-1853
    • (1999) J Cell Sci , vol.112 , pp. 1843-1853
    • Maas-Szabowski, N.1    Shimotoyodome, A.2    Fusenig, N.E.3
  • 65
    • 0033603479 scopus 로고    scopus 로고
    • Parathyroid hormone-related protein is a positive regulator of keratinocyte growth factor expression by normal dermal fibroblasts
    • Blomme E.A.G., Sugimoto Y., Lin Y.C., et al. Parathyroid hormone-related protein is a positive regulator of keratinocyte growth factor expression by normal dermal fibroblasts. Mol Cell Endocrinol 152 (1999) 189-197
    • (1999) Mol Cell Endocrinol , vol.152 , pp. 189-197
    • Blomme, E.A.G.1    Sugimoto, Y.2    Lin, Y.C.3
  • 66
    • 0034623310 scopus 로고    scopus 로고
    • Defective terminal differentiation and hypoplasia of the epidermis in mice lacking the Fgf10 gene
    • Suzuki K., Yamanishi K., Mori O., et al. Defective terminal differentiation and hypoplasia of the epidermis in mice lacking the Fgf10 gene. FEBS Lett 481 (2000) 53-56
    • (2000) FEBS Lett , vol.481 , pp. 53-56
    • Suzuki, K.1    Yamanishi, K.2    Mori, O.3
  • 68
    • 0037420518 scopus 로고    scopus 로고
    • Psoriasis
    • Lebwohl M. Psoriasis. Lancet 361 (2003) 1197-1204
    • (2003) Lancet , vol.361 , pp. 1197-1204
    • Lebwohl, M.1
  • 70
    • 0036721609 scopus 로고    scopus 로고
    • Quantitative differences in chemokine receptor engagement generate diversity in integrin-dependent lymphocyte adhesion
    • D'Ambrosio D., Albanesi C., Lang R., et al. Quantitative differences in chemokine receptor engagement generate diversity in integrin-dependent lymphocyte adhesion. J Immunol. 169 (2002) 2303-2312
    • (2002) J Immunol. , vol.169 , pp. 2303-2312
    • D'Ambrosio, D.1    Albanesi, C.2    Lang, R.3
  • 71
    • 0034671624 scopus 로고    scopus 로고
    • C-C chemokine receptor 6 is essential for arrest of a subset of memory T cells on activated dermal microvascular endothelial cells under physiologic flow conditions in vitro
    • Fitzhugh D.J., Naik S., Caughman S.W., et al. C-C chemokine receptor 6 is essential for arrest of a subset of memory T cells on activated dermal microvascular endothelial cells under physiologic flow conditions in vitro. J Immunol 165 (2000) 6677-6681
    • (2000) J Immunol , vol.165 , pp. 6677-6681
    • Fitzhugh, D.J.1    Naik, S.2    Caughman, S.W.3
  • 72
    • 0035012168 scopus 로고    scopus 로고
    • Fractalkine (CX3CL1) as an amplification circuit of polarized Th1 responses
    • Fraticelli P., Sironi M., Bianchi G., et al. Fractalkine (CX3CL1) as an amplification circuit of polarized Th1 responses. J Clin Invest 107 (2001) 1173-1181
    • (2001) J Clin Invest , vol.107 , pp. 1173-1181
    • Fraticelli, P.1    Sironi, M.2    Bianchi, G.3
  • 73
    • 0041464828 scopus 로고    scopus 로고
    • Aberrant signalling and transcription factor activation as an explanation for the defective growth control and differentiation of keratinocytes in psoriasis: a hypothesis
    • McKenzie R.C., and Sabin E. Aberrant signalling and transcription factor activation as an explanation for the defective growth control and differentiation of keratinocytes in psoriasis: a hypothesis. Exp Dermatol 12 (2003) 337-345
    • (2003) Exp Dermatol , vol.12 , pp. 337-345
    • McKenzie, R.C.1    Sabin, E.2
  • 74
    • 33746177400 scopus 로고    scopus 로고
    • Signaling downstream of p38 psoriasis
    • Simon J.C., and Darragh J. Signaling downstream of p38 psoriasis. J Invest Dermatol 126 (2006) 1689-1691
    • (2006) J Invest Dermatol , vol.126 , pp. 1689-1691
    • Simon, J.C.1    Darragh, J.2
  • 75
    • 0036644335 scopus 로고    scopus 로고
    • Impaired IFN-γ-dependent inflammatory responses in human keratinocytes overexpressing the suppressor of cytokine signaling 1
    • Federici M., Giustizieri M.L., Scarponi C., et al. Impaired IFN-γ-dependent inflammatory responses in human keratinocytes overexpressing the suppressor of cytokine signaling 1. J Immunol. 169 (2002) 434-442
    • (2002) J Immunol. , vol.169 , pp. 434-442
    • Federici, M.1    Giustizieri, M.L.2    Scarponi, C.3


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