Pyrvinium attenuates hedgehog signaling downstream of smoothened

Cancer Research

Volumn 74, Issue 17, 2014, Pages 4811-4821

  Li, Bin ^a   Fei, Dennis Liang ^a   Flaveny, Colin A ^a   Dahmane, Nadia ^b   Baubet, Valérie ^b   Wang, Zhiqiang ^a   Bai, Feng ^a   Pei, Xin Hai ^a,c   Rodriguez Blanco, Jezabel ^a   Hang, Brian ^d   Orton, Darren ^e   Han, Lu ^a   Wang, Baolin ^f   Capobianco, Anthony J ^a,c   Lee, Ethan ^d   Robbins, David J ^a,c  

^a UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

^c UNIVERSITY OF MIAMI   (United States)

^d VANDERBILT INGRAM CANCER CENTER   (United States)

^e StemSynergy Therapeutics Inc   (United States)

^f WEILL CORNELL MEDICAL COLLEGE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CASEIN KINASE IALPHA; G PROTEIN COUPLED RECEPTOR; GLI PROTEIN; ONCOPROTEIN; PYRVINIUM EMBONATE; SONIC HEDGEHOG PROTEIN; TRANSACTIVATOR PROTEIN; TRANSCRIPTION FACTOR;

3T3 CELL LINE; ANIMAL; CARCINOMA, BASAL CELL; CELL LINE; DRUG EFFECTS; HEK293 CELL LINE; HUMAN; MEDULLOBLASTOMA; METABOLISM; MOUSE; NUDE MOUSE; SIGNAL TRANSDUCTION;

ANIMALS; CARCINOMA, BASAL CELL; CASEIN KINASE IALPHA; CELL LINE; HEDGEHOG PROTEINS; HEK293 CELLS; HUMANS; MEDULLOBLASTOMA; MICE; MICE, NUDE; NIH 3T3 CELLS; ONCOGENE PROTEINS; PYRVINIUM COMPOUNDS; RECEPTORS, G-PROTEIN-COUPLED; SIGNAL TRANSDUCTION; TRANS-ACTIVATORS; TRANSCRIPTION FACTORS;

EID: 84907043262     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-14-0317     Document Type: Article

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