Pyrvinium pamoate does not activate protein kinase CK1, but promotes Akt/PKB down-regulation and GSK3 activation

Biochemical Journal

Volumn 452, Issue 1, 2013, Pages 131-137

  Venerando, Andrea ^a   Girardi, Cristina ^a   Ruzzene, Maria ^a   Pinna, Lorenzo A ^a  

^a UNIVERSITY OF PADOVA   (Italy)

Author keywords

catenin; Akt protein kinase B (Akt PKB); Glycogen synthase kinase 3 (GSK3); Protein kinase CK1; Pyrvinium pamoate; Wnt signalling

Indexed keywords

CK1 ALPHA PROTEIN KINASE; GLYCOGEN SYNTHASE KINASE 3; PROTEIN KINASE; PROTEIN KINASE B; PYRVINIUM EMBONATE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CATALYSIS; CONTROLLED STUDY; DRUG EFFECT; DRUG EFFICACY; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEPHOSPHORYLATION; RECEPTOR DOWN REGULATION; SIGNAL TRANSDUCTION;

ANIMALS; CASEIN KINASE I; CRICETINAE; DOWN-REGULATION; ENZYME ACTIVATION; GLYCOGEN SYNTHASE KINASE 3; HEK293 CELLS; HUMANS; PROTO-ONCOGENE PROTEINS C-AKT; PYRVINIUM COMPOUNDS;

EID: 84876924060     PISSN: 02646021     EISSN: 14708728     Source Type: Journal    
DOI: 10.1042/BJ20121140     Document Type: Article

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