The phosphatidyl-myo-inositol mannosyltransferase PimA is essential for Mycobacterium tuberculosis growth in vitro and in vivo

Journal of Bacteriology

Volumn 196, Issue 19, 2014, Pages 3441-3451

  Boldrin, Francesca ^a   Ventura, Marcello ^a   Degiacomi, Giulia ^a   Ravishankar, Sudha ^b   Sala, Claudia ^c   Svetlikova, Zuzana ^d   Ambady, Anisha ^b   Dhar, Neeraj ^c   Kordulakova, Jana ^d   Zhang, Ming ^c   Serafini, Agnese ^a   Vishwas, V G ^b   Kolly, Gaëlle S ^c   Kumar, Naveen ^b   Palù, Giorgio ^a   Guerin, Marcelo E ^e,f   Mikusova, Katarina ^d   Cole, Katarina Mikusova ^c   Manganelli, Riccardo ^a  

^a UNIVERSITY OF PADOVA   (Italy)

^b ASTRAZENECA   (United Kingdom)

^c EPFL   (Switzerland)

^d Faculty of Natural Sciences   (Slovakia)

^e UNIVERSITY OF THE BASQUE COUNTRY UPV EHU   (Spain)

^f BASQUE FOUNDATION FOR SCIENCE   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL ENZYME; GLYCOSYLTRANSFERASE; GUANOSINE DIPHOSPHATE MANNOSE; PIMA ENZYME; UNCLASSIFIED DRUG; BACTERIAL PROTEIN; MANNOSYLTRANSFERASE; PHOSPHATIDYL MYO INOSITOL MANNOSYLTRANSFERASE PIMA, MYCOBACTERIUM SMEGMATIS; PHOSPHATIDYL-MYO-INOSITOL MANNOSYLTRANSFERASE PIMA, MYCOBACTERIUM SMEGMATIS; PHOSPHATIDYLINOSITOL; PHOSPHATIDYLINOSITOL MANNOSIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BACTERIAL GROWTH; BACTERIAL MEMBRANE; BACTERIUM CULTURE; CONTROLLED STUDY; CYTOPLASM; DOWN REGULATION; ENZYME SYNTHESIS; FEMALE; GENE SILENCING; IN VITRO STUDY; IN VIVO STUDY; LUNG CLEARANCE; LUNG TUBERCULOSIS; MOUSE; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PHENOTYPE; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN FUNCTION; ANIMAL; BIOSYNTHESIS; C57BL MOUSE; ENZYMOLOGY; GENETICS; GROWTH, DEVELOPMENT AND AGING; HUMAN; MACROPHAGE; METABOLISM; MICROBIOLOGY; TUBERCULOSIS;

ANIMALS; BACTERIAL PROTEINS; FEMALE; HUMANS; MACROPHAGES; MANNOSYLTRANSFERASES; MICE; MICE, INBRED C57BL; MYCOBACTERIUM TUBERCULOSIS; PHOSPHATIDYLINOSITOLS; TUBERCULOSIS;

EID: 84907015388     PISSN: 00219193     EISSN: 10985530     Source Type: Journal    
DOI: 10.1128/JB.01346-13     Document Type: Article

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