Effects of agave nectar versus sucrose on weight gain, adiposity, blood glucose, insulin, and lipid responses in mice

Journal of Medicinal Food

Volumn 17, Issue 9, 2014, Pages 1017-1021

  Hooshmand, Shirin ^a   Holloway, Brittany ^a   Nemoseck, Tricia ^a   Cole, Sarah ^a   Petrisko, Yumi ^a   Hong, Mee Young ^a   Kern, Mark ^a  

^a SAN DIEGO STATE UNIVERSITY   (United States)

Author keywords

cholesterol; fructose; glucose; obesity; triglycerides

Indexed keywords

CARBOHYDRATE; GLUCOSE; INSULIN; LIPID; SUCROSE; TRIACYLGLYCEROL; FRUCTOSE; GLUCOSE BLOOD LEVEL; NECTAR; SUGAR INTAKE;

AGAVE; AGAVE NECTAR; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD SAMPLING; BODY WEIGHT; CHOLESTEROL BLOOD LEVEL; COMPARATIVE STUDY; CONTROLLED STUDY; DIET RESTRICTION; DIET SUPPLEMENTATION; EPIDIDYMIS FAT; FEEDING; GLUCOSE BLOOD LEVEL; GLUCOSE METABOLISM; INSULIN BLOOD LEVEL; LIPID BLOOD LEVEL; MALE; MOUSE; NECTAR; NONHUMAN; OBESITY; WEIGHT GAIN; ADIPOSE TISSUE; ADVERSE EFFECTS; ANIMAL; BLOOD; DIET; DRUG EFFECTS; INSTITUTE FOR CANCER RESEARCH MOUSE; METABOLISM; PHARMACOLOGY; SUGAR INTAKE;

ADIPOSE TISSUE; ADIPOSITY; AGAVE; ANIMALS; BLOOD GLUCOSE; DIET; DIETARY SUCROSE; FRUCTOSE; INSULIN; LIPIDS; MALE; MICE, INBRED ICR; OBESITY; PLANT NECTAR; WEIGHT GAIN;

EID: 84906988953     PISSN: 1096620X     EISSN: 15577600     Source Type: Journal    
DOI: 10.1089/jmf.2013.0162     Document Type: Article

References (20)

1. Johnson RJ, Segal MS, Sautin Y, et al.: Potential role of sugar (fructose) in the epidemic of hypertension, obesity and the metabolic syndrome, diabetes, kidney disease, and cardiovascular disease. Am J Clin Nutr 2007;86:899-906.
2. Tappy L, Le KA, Tran C, Paquot N: Fructose and metabolic disease: new findings, new questions. Nutrition 2010;261044-261049.
3. Willems JL, Low NH: Major carbohydrate, polyol and oligo-saccharide profiles of agave syrup. Application of this data to authenticity analysis. J Agric. Food Chem 2012;60:8745-8754.
4. Michel-Cuello C, Juarez-Flores BI, Aguirre-Rivera R, Pinos-Rodriguez JM: Quantitative characterization of nonstructural carbohydrates of mezcal agave. J Agric Food Chem 2008;56: 5753-5757.
5. Figlewicz DP, Ioannou G, Bennett J, Kittleson S, Savard C, Roth CL: Effect of moderate intake of sweeteners on metabolic health in the rat. Physiol Behav 2009;98:618-624.
6. White JS: Misconceptions about high-fructose corn syrup: is it uniquely responsible for obesity, reactive dicarbonyl compounds, and advanced glycation endproducts. J Nutr 2009;139:1219-1227.
7. Harris RB, Apolzan JW: Changes in glucose tolerance and leptin responsiveness of rats offered a choice of lard, sucrose and chow. Am J Physiol Regul Integr Comp Physiol 2012;302:1327-1339.
8. Busserolles J, Rock E, Gueux E, Mazur A, Grolier P, Rayssiguier Y: Short-term consumption of a high-sucrose diet has a pro-oxidant effect in rats. Br J Nutr 2002;87:337-342.
9. Kanarek RB, Orthen-Gambill N: Differential effects of sucrose, fructose and glucose on carbohydrate-induced obesity in rats. J Nutr 1982;112:1546-1554.
10. Robert L, Narcy A, Rayssiguier Y, Mazur A, Remsey C: Lipid metabolism and antioxidant status in sucrose vs. potato-fed rats. J Am Coll Nutr 2008;27:109-116.
11. Wheeler ML, Pi-Sunyer FX: Carbohydrate issues: type and amount. J Am Diet Assoc 2008;108:34-39.
12. Sumiyoshi M, Sakanaka M, Kimura Y: Chronic intake of high-fat and high-sucrose diets differentially affects glucose intolerance in mice. J Nutr 2006;136:582-587.
13. Urias-Silvas JE, Cani PD, Delmee E, Neyrinck A, Lopez MG, Delzenne NM: Physiological effects of dietary fructans extracted from Agave Tequilana Gto. and Dasylirion spp. Br J Nutr 2008; 99:254-261.
14. Nemoseck TM, Carmody EG, Furchner-Evanson A, et al.: Honey promotes lower weight gain, adiposity, and triglycerides than sucrose in rats. Nutr Res 2011;31:55-60.
15. Rizwan K, Zubair M, Rasool N, Riaz M, Muhammad ZU, de Feo V: Phytochemical and biological studies of agave attenuate. Int J Mol Sci 2012;13:6440-6451.
16. American Dietetic Association: Position of the American Dietetic Association: use of nutritive and nonnutritive sweeteners. J Am Diet Assoc 2004;104:255-275.
17. Phillips KM, Carlsen MH, Blomhoff R: Total antioxidant content of alternative to refined sugar. J Am Diet Assoc 2009;109: 64-71
18. The International Organic Agave Alliance: http://theioaa.com (accessed April 9, 2013).
19. Atkinson FS, Foster-Powell K, Brand-Miller JC: International table of glycemic index and glycemic load values: 2008. Diabetes Care 2008;31:2281-2283.
20. Arora S, Anubhuti: Role of neuropeptides in appetite regulation and obesity. Neuropeptides 2006;40:375-401.