메뉴 건너뛰기




Volumn 37, Issue 9, 2014, Pages 1486-1494

Cytoprotective effect of kaempferol on paraquat-exposed BEAS-2B cells via modulating expression of MUC5AC

Author keywords

Human bronchial epithelial BEAS 2B cell; Kaempferol; MUC5AC; Nuclear factor kappa B; Reactive oxygen species

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; KAEMPFEROL; LACTATE DEHYDROGENASE; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; MUCIN 5AC; PARAQUAT; REACTIVE OXYGEN METABOLITE; SILYMARIN; SMALL INTERFERING RNA; STRESS ACTIVATED PROTEIN KINASE; THIOCTIC ACID; HERBICIDE; KAEMPFEROL DERIVATIVE; MUC5AC PROTEIN, HUMAN; PROTECTIVE AGENT;

EID: 84906962954     PISSN: 09186158     EISSN: 13475215     Source Type: Journal    
DOI: 10.1248/bpb.b14-00239     Document Type: Article
Times cited : (16)

References (40)
  • 2
    • 70349306123 scopus 로고    scopus 로고
    • Regulation of mucin expression in respiratory diseases
    • Turner J, Jones CE. Regulation of mucin expression in respiratory diseases. Biochem. Soc. Trans., 37, 877-881 (2009).
    • (2009) Biochem. Soc. Trans. , vol.37 , pp. 877-881
    • Turner, J.1    Jones, C.E.2
  • 3
    • 56049090789 scopus 로고    scopus 로고
    • Gene-environment interactions in environmental lung diseases
    • discussion, 180-183
    • Kleeberger SR, Cho HY. Gene-environment interactions in environmental lung diseases. Novartis Found. Symp., 293, 168-178, discussion, 180-183 (2008).
    • (2008) Novartis Found. Symp. , vol.293 , pp. 168-178
    • Kleeberger, S.R.1    Cho, H.Y.2
  • 4
    • 0024998101 scopus 로고
    • Reactive oxygen species and airway infammation
    • Barnes PJ. Reactive oxygen species and airway infammation. Free Radic. Biol. Med., 9, 235-243 (1990).
    • (1990) Free Radic. Biol. Med. , vol.9 , pp. 235-243
    • Barnes, P.J.1
  • 5
    • 33644781601 scopus 로고    scopus 로고
    • Oxidant and antioxidant balance in the airways and airway diseases
    • Rahman I, Biswas SK, Kode A. Oxidant and antioxidant balance in the airways and airway diseases. Eur. J. Pharmacol., 533, 222-239 (2006).
    • (2006) Eur. J. Pharmacol. , vol.533 , pp. 222-239
    • Rahman, I.1    Biswas, S.K.2    Kode, A.3
  • 6
    • 0034141938 scopus 로고    scopus 로고
    • Oxidative stress causes mucin synthesis via transactivation of epidermal growth factor receptor: Role of neutrophils
    • Takeyama K, Dabbagh K, Jeong Shim J, Dao-Pick T, Ueki I.F., Nadel JA. Oxidative stress causes mucin synthesis via transactivation of epidermal growth factor receptor: role of neutrophils. J. Immunol., 164, 1546-1552 (2000).
    • (2000) J. Immunol. , vol.164 , pp. 1546-1552
    • Takeyama, K.1    Dabbagh, K.2    Jeong Shim, J.3    Dao-Pick, T.4    Ueki, I.F.5    Nadel, J.A.6
  • 12
    • 84864134568 scopus 로고    scopus 로고
    • Antioxidant effect of silymarin on paraquat-induced human lung adenocarcinoma A549 cell line
    • Podder B, Kim YS, Zerin T, Song HY. Antioxidant effect of silymarin on paraquat-induced human lung adenocarcinoma A549 cell line. Food Chem. Toxicol., 50, 3206-3214 (2012).
    • (2012) Food Chem. Toxicol. , vol.50 , pp. 3206-3214
    • Podder, B.1    Kim, Y.S.2    Zerin, T.3    Song, H.Y.4
  • 14
    • 80053278810 scopus 로고    scopus 로고
    • Continuous hypoxia attenuates paraquat-induced cytotoxicity in the human A549 lung carcinoma cell line
    • Kim H, Lee SW, Baek K.M., Park JS, Min JH. Continuous hypoxia attenuates paraquat-induced cytotoxicity in the human A549 lung carcinoma cell line. Exp. Mol. Med., 43, 494-500 (2011).
    • (2011) Exp. Mol. Med. , vol.43 , pp. 494-500
    • Kim, H.1    Lee, S.W.2    Baek, K.M.3    Park, J.S.4    Min, J.H.5
  • 15
    • 23844543708 scopus 로고    scopus 로고
    • Extraction and identification of natural antioxidant from sideritis euboea (mountain tea)
    • Tsaknis J, Lalas S. Extraction and identification of natural antioxidant from Sideritis euboea (mountain tea). J. Agric. Food Chem., 53, 6375-6381 (2005).
    • (2005) J. Agric. Food Chem. , vol.53 , pp. 6375-6381
    • Tsaknis, J.1    Lalas, S.2
  • 17
    • 80054741464 scopus 로고    scopus 로고
    • Flavonol kaempferol improves chronic hypergly-cemia-impaired pancreatic beta-cell viability and insulin secretory function
    • Zhang Y, Liu D. Flavonol kaempferol improves chronic hypergly-cemia-impaired pancreatic beta-cell viability and insulin secretory function. Eur. J. Pharmacol., 670, 325-332 (2011).
    • (2011) Eur. J. Pharmacol. , vol.670 , pp. 325-332
    • Zhang, Y.1    Liu, D.2
  • 20
    • 3242659216 scopus 로고    scopus 로고
    • Biological activity of five anti-bacterial favonoids from combretum erythrophyllum (Combreta-ceae)
    • Martini ND, Katerere DR, Eloff JN. Biological activity of five anti-bacterial favonoids from Combretum erythrophyllum (Combreta-ceae). J. Ethnopharmacol., 93, 207-212 (2004).
    • (2004) J. Ethnopharmacol. , vol.93 , pp. 207-212
    • Martini, N.D.1    Katerere, D.R.2    Eloff, J.N.3
  • 21
    • 0242467845 scopus 로고    scopus 로고
    • Elevation of oxidative free radicals in alzheimer's disease models can be attenuated by ginkgo biloba extract EGb 761
    • Smith JV, Luo Y. Elevation of oxidative free radicals in Alzheimer's disease models can be attenuated by Ginkgo biloba extract EGb 761. J. Alzheimer's Dis., 5, 287-300 (2003).
    • (2003) J. Alzheimer's Dis. , vol.5 , pp. 287-300
    • Smith, J.V.1    Luo, Y.2
  • 22
    • 0346505340 scopus 로고    scopus 로고
    • The IKK NF-kappa B system: A treasure trove for drug development
    • Karin M, Yamamoto Y, Wang QM. The IKK NF-kappa B system: a treasure trove for drug development. Nat. Rev. Drug Discov., 3, 17-26 (2004).
    • (2004) Nat. Rev. Drug Discov. , vol.3 , pp. 17-26
    • Karin, M.1    Yamamoto, Y.2    Wang, Q.M.3
  • 23
    • 46049085866 scopus 로고    scopus 로고
    • NF-kappa B and nrf2 as potential chemopreventive targets of some anti-infammatory and antioxidative phytonutrients with anti-infammatory and antioxidative activities
    • Surh YJ. NF-kappa B and Nrf2 as potential chemopreventive targets of some anti-infammatory and antioxidative phytonutrients with anti-infammatory and antioxidative activities. Asia Pac. J. Clin. Nutr., 17 (Suppl. 1), 269-272 (2008).
    • (2008) Asia Pac. J. Clin. Nutr. , vol.17 , Issue.SUPPL. 1 , pp. 269-272
    • Surh, Y.J.1
  • 24
    • 55949120110 scopus 로고    scopus 로고
    • Activation of nrf2-antioxidant signaling attenuates NFkappaB-infam-matory response and elicits apoptosis
    • Li W, Khor TO, Xu C, Shen G., Jeong WS, Yu S, Kong AN. Activation of Nrf2-antioxidant signaling attenuates NFkappaB-infam-matory response and elicits apoptosis. Biochem. Pharmacol, 76, 1485-1489 (2008).
    • (2008) Biochem. Pharmacol , vol.76 , pp. 1485-1489
    • Li, W.1    Khor, T.O.2    Xu, C.3    Shen, G.4    Jeong, W.S.5    Yu, S.6    Kong, A.N.7
  • 25
    • 84864423315 scopus 로고    scopus 로고
    • Narin-gin attenuates EGF-induced MUC5AC secretion in A549 cells by suppressing the cooperative activities of MAPKs-AP-1 and IKKs-ikappab-NF-kappaB signaling pathways
    • Nie YC, Wu H, Li P.B., Xie LM, Luo YL, Shen JG, Su WW. Narin-gin attenuates EGF-induced MUC5AC secretion in A549 cells by suppressing the cooperative activities of MAPKs-AP-1 and IKKs-IkappaB-NF-kappaB signaling pathways. Eur. J. Pharmacol., 690, 207-213 (2012).
    • (2012) Eur. J. Pharmacol. , vol.690 , pp. 207-213
    • Nie, Y.C.1    Wu, H.2    Li, P.B.3    Xie, L.M.4    Luo, Y.L.5    Shen, J.G.6    Su, W.W.7
  • 26
    • 79955507341 scopus 로고    scopus 로고
    • α-melanocyte-stimulating hormone inhibits tumor necrosis factor alpha-stimulated MUC5AC expression in human nasal epithelial cells
    • Lee SN, Ryu JH, Joo J.H., Choi YH, Lee HJ, Kim YJ, Kim K.B., Yoon JH. α-Melanocyte-stimulating hormone inhibits tumor necrosis factor alpha-stimulated MUC5AC expression in human nasal epithelial cells. Am. J. Respir. Cell. Mol. Biol., 44, 716-724 (2011).
    • (2011) Am. J. Respir. Cell. Mol. Biol. , vol.44 , pp. 716-724
    • Lee, S.N.1    Ryu, J.H.2    Joo, J.H.3    Choi, Y.H.4    Lee, H.J.5    Kim, Y.J.6    Kim, K.B.7    Yoon, J.H.8
  • 27
    • 0037593635 scopus 로고    scopus 로고
    • Interleukin-1 beta and tumor necrosis factor-alpha induce MUC5AC overexpression through a mechanism involving ERK/p38 mitogen-activated protein kinases-MSK1-CREB activation in human airway epithelial cells
    • Song KS, Lee WJ, Chung K.C., Koo JS, Yang EJ, Choi JY, Yoon JH. Interleukin-1 beta and tumor necrosis factor-alpha induce MUC5AC overexpression through a mechanism involving ERK/p38 mitogen-activated protein kinases-MSK1-CREB activation in human airway epithelial cells. J. Biol. Chem., 278, 23243-23250 (2003).
    • (2003) J. Biol. Chem. , vol.278 , pp. 23243-23250
    • Song, K.S.1    Lee, W.J.2    Chung, K.C.3    Koo, J.S.4    Yang, E.J.5    Choi, J.Y.6    Yoon, J.H.7
  • 28
    • 84883807925 scopus 로고    scopus 로고
    • The protective effect of prunella vulgaris ethanol extract against vascular infammation in TNF-α-stimulated human aortic smooth muscle cells
    • Park SH, Koo HJ, Sung Y.Y., Kim HK. The protective effect of Prunella vulgaris ethanol extract against vascular infammation in TNF-α-stimulated human aortic smooth muscle cells. BMB Rep., 46, 352-357 (2013).
    • (2013) BMB Rep. , vol.46 , pp. 352-357
    • Park, S.H.1    Koo, H.J.2    Sung, Y.Y.3    Kim, H.K.4
  • 31
    • 84862907830 scopus 로고    scopus 로고
    • Kaempferol suppresses eosinophil infiltration and airway infammation in airway epithelial cells and in mice with allergic asthma
    • Gong JH, Shin D, Han S.Y., Kim JL, Kang YH. Kaempferol suppresses eosinophil infiltration and airway infammation in airway epithelial cells and in mice with allergic asthma. J. Nutr., 142, 47-56 (2012).
    • (2012) J. Nutr. , vol.142 , pp. 47-56
    • Gong, J.H.1    Shin, D.2    Han, S.Y.3    Kim, J.L.4    Kang, Y.H.5
  • 33
    • 80051512571 scopus 로고    scopus 로고
    • Neuroprotective effect of kaempferol against a 1-meth-yl-4-phenyl-1,2,3,6-tetrahydropyridine-induced mouse model of parkinson's disease
    • Li S, Pu X P. Neuroprotective effect of kaempferol against a 1-meth-yl-4-phenyl-1,2,3,6-tetrahydropyridine-induced mouse model of Parkinson's disease. Biol. Pharm. Bull., 34, 1291-1296 (2011).
    • (2011) Biol. Pharm. Bull. , vol.34 , pp. 1291-1296
    • Li, S.1    Pu, X.P.2
  • 34
    • 45849129080 scopus 로고    scopus 로고
    • Kaempferol protects ischemia/reperfusion-induced cardiac damage through the regulation of endoplasmic reticulum stress
    • Kim DS, Ha KC, Kwon D.Y., Kim MS, Kim HR, Chae SW, Chae HJ. Kaempferol protects ischemia/reperfusion-induced cardiac damage through the regulation of endoplasmic reticulum stress. Immuno-pharmacol. Immunotoxicol., 30, 257-270 (2008).
    • (2008) Immuno-pharmacol. Immunotoxicol. , vol.30 , pp. 257-270
    • Kim, D.S.1    Ha, K.C.2    Kwon, D.Y.3    Kim, M.S.4    Kim, H.R.5    Chae, S.W.6    Chae, H.J.7
  • 36
    • 2442540251 scopus 로고    scopus 로고
    • Effects of betaine, coumarin and favonoids on mucin release from cultured hamster tracheal surface epithelial cells
    • Lee CJ, Lee JH, Seok J.H., Hur GM, Park J, Bae S, Lim J.H., Park YC. Effects of betaine, coumarin and favonoids on mucin release from cultured hamster tracheal surface epithelial cells. Phytother. Res., 18, 301-305 (2004).
    • (2004) Phytother. Res. , vol.18 , pp. 301-305
    • Lee, C.J.1    Lee, J.H.2    Seok, J.H.3    Hur, G.M.4    Park, J.5    Bae, S.6    Lim, J.H.7    Park, Y.C.8
  • 37
    • 70450175844 scopus 로고    scopus 로고
    • Kaemp-ferol and quercetin, essential ingredients in ginkgo biloba extract, inhibit interleukin-1beta-induced MUC5AC gene expression in human airway epithelial cells
    • Kwon SH, Nam JI, Kim S.H., Kim JH, Yoon JH, Kim KS. Kaemp-ferol and quercetin, essential ingredients in Ginkgo biloba extract, inhibit interleukin-1beta-induced MUC5AC gene expression in human airway epithelial cells. Phytother. Res., 23, 1708-1712 (2009).
    • (2009) Phytother. Res. , vol.23 , pp. 1708-1712
    • Kwon, S.H.1    Nam, J.I.2    Kim, S.H.3    Kim, J.H.4    Yoon, J.H.5    Kim, K.S.6
  • 40
    • 14144251241 scopus 로고    scopus 로고
    • Dual oxidase 1-dependent MUC5AC mucin expression in cultured human airway epithelial cells
    • Shao MX, Nadel JA. Dual oxidase 1-dependent MUC5AC mucin expression in cultured human airway epithelial cells. Proc. Natl. Acad. Sci. U.S.A., 102, 767-772 (2005).
    • (2005) Proc. Natl. Acad. Sci. U.S.A. , vol.102 , pp. 767-772
    • Shao, M.X.1    Nadel, J.A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.