Naringin attenuates EGF-induced MUC5AC secretion in A549 cells by suppressing the cooperative activities of MAPKs-AP-1 and IKKs-IκB-NF- κB signaling pathways

European Journal of Pharmacology

Volumn 690, Issue 1-3, 2012, Pages 207-213

  Nie, Yi Chu ^a   Wu, Hao ^b   Li, Pei Bo ^a   Xie, Li Ming ^a   Luo, Yu Long ^a   Shen, Jian Gang ^b   Su, Wei Wei ^a  

^a SUN YAT SEN UNIVERSITY   (China)

^b THE UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

Activator protein 1; Epithelium growth factor; Epithelium growth factor receptor; MUC5AC; Naringin; Nuclear factor kappa B

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; AURANTIIN; AZITHROMYCIN; BENZYLOXYCARBONYLLEUCYLLEUCYLLEUCINAL; EPIDERMAL GROWTH FACTOR; EPIDERMAL GROWTH FACTOR RECEPTOR; I KAPPA B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; MUCIN 5AC; SP 203580; STRESS ACTIVATED PROTEIN KINASE; TRANSCRIPTION FACTOR AP 1; TRANSCRIPTION FACTOR RELA; UNCLASSIFIED DRUG;

ARTICLE; CELL NUCLEUS; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; MUC5AC GENE; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PROTEIN SECRETION; SIGNAL TRANSDUCTION;

CELL LINE, TUMOR; CELL SURVIVAL; EPIDERMAL GROWTH FACTOR; FLAVANONES; GENE EXPRESSION REGULATION; HUMANS; I-KAPPA B KINASE; MAP KINASE SIGNALING SYSTEM; MUCIN 5AC; NF-KAPPA B; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PROTEIN KINASE INHIBITORS; TRANSCRIPTION FACTOR AP-1;

EID: 84864423315     PISSN: 00142999     EISSN: 18790712     Source Type: Journal    
DOI: 10.1016/j.ejphar.2012.06.040     Document Type: Article

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