메뉴 건너뛰기




Volumn 94, Issue 9, 2014, Pages 950-965

Micheliolide, a new sesquiterpene lactone that inhibits intestinal inflammation and colitis-associated cancer

Author keywords

[No Author keywords available]

Indexed keywords

ANIMALS; BASE SEQUENCE; BLOTTING, WESTERN; CELL LINE; COLITIS; COLORECTAL NEOPLASMS; DNA PRIMERS; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; HUMANS; LIPOPOLYSACCHARIDES; MAGNETIC RESONANCE SPECTROSCOPY; MICE; MICE, INBRED C57BL; NF-KAPPA B; REAL-TIME POLYMERASE CHAIN REACTION; SESQUITERPENES, GUAIANE;

EID: 84906829810     PISSN: 00236837     EISSN: 15300307     Source Type: Journal    
DOI: 10.1038/labinvest.2014.89     Document Type: Article
Times cited : (86)

References (53)
  • 1
    • 2442563304 scopus 로고    scopus 로고
    • Clinical epidemiology of inflammatory bowel disease:Incidence prevalence and environmental influences
    • Loftus Jr EV. Clinical epidemiology of inflammatory bowel disease:Incidence, prevalence, and environmental influences. Gastroenterology2004;126:1504-1517.
    • (2004) Gastroenterology , vol.126 , pp. 1504-1517
    • Loftus Jr., E.V.1
  • 2
    • 79952745080 scopus 로고    scopus 로고
    • Experimental inflammatory bowel disease: Insightsinto the host-microbiota dialog
    • Saleh M, Elson CO. Experimental inflammatory bowel disease: Insightsinto the host-microbiota dialog. Immunity 2011;34:293-302.
    • (2011) Immunity , vol.34 , pp. 293-302
    • Saleh, M.1    Elson, C.O.2
  • 3
    • 79959216005 scopus 로고    scopus 로고
    • Genetics and pathogenesis ofinflammatory bowel disease
    • Khor B, Gardet A, Xavier RJ. Genetics and pathogenesis ofinflammatory bowel disease. Nature 2011;474:307-317.
    • (2011) Nature , vol.474 , pp. 307-317
    • Khor, B.1    Gardet, A.2    Xavier, R.J.3
  • 4
    • 0035874469 scopus 로고    scopus 로고
    • Cloning of a lymphatic peptide/histidine transporter
    • Sakata K, Yamashita T, Maeda M, et al. Cloning of a lymphatic peptide/histidine transporter. Biochem J 2001;356(Pt 1):53-60.
    • (2001) Biochem J , vol.356 , Issue.PART. 1 , pp. 53-60
    • Sakata, K.1    Yamashita, T.2    Maeda, M.3
  • 7
    • 0037180757 scopus 로고    scopus 로고
    • Inflammation and cancer
    • Coussens LM, Werb Z. Inflammation and cancer. Nature 2002;420:860-867.
    • (2002) Nature , vol.420 , pp. 860-867
    • Coussens, L.M.1    Werb, Z.2
  • 8
    • 32944474237 scopus 로고    scopus 로고
    • Innate immunity gone awry: Linkingmicrobial infections to chronic inflammation and cancer
    • Karin M, Lawrence T, Nizet V. Innate immunity gone awry: Linkingmicrobial infections to chronic inflammation and cancer. Cell2006;124:823-835.
    • (2006) Cell , vol.124 , pp. 823-835
    • Karin, M.1    Lawrence, T.2    Nizet, V.3
  • 11
    • 0031915368 scopus 로고    scopus 로고
    • Sesquiterpene lactonesspecifically inhibit activation of NF-kappa B by preventing thedegradation of i kappa B-alpha and i kappa B-beta
    • Hehner SP, Heinrich M, Bork PM, et al. Sesquiterpene lactonesspecifically inhibit activation of NF-kappa B by preventing thedegradation of I kappa B-alpha and I kappa B-beta. J Biol Chem1998;273:1288-1297.
    • (1998) J Biol Chem , vol.273 , pp. 1288-1297
    • Hehner, S.P.1    Heinrich, M.2    Bork, P.M.3
  • 12
    • 34249892217 scopus 로고    scopus 로고
    • Parthenolide inhibits IkappaBkinase, NF-kappaB activation, and inflammatory response in cysticfibrosis cells and mice
    • Saadane A, Masters S, DiDonato J, et al. Parthenolide inhibits IkappaBkinase, NF-kappaB activation, and inflammatory response in cysticfibrosis cells and mice. Am J Respir Cell Mol Biol 2007;36:728-736.
    • (2007) Am J Respir Cell Mol Biol , vol.36 , pp. 728-736
    • Saadane, A.1    Masters, S.2    Didonato, J.3
  • 13
    • 84856089700 scopus 로고    scopus 로고
    • Parthenolide, an inhibitor of the nuclearfactor-kappaB pathway, ameliorates dextran sulfate sodium-inducedcolitis in mice
    • Zhao ZJ, Xiang JY, Liu L, et al. Parthenolide, an inhibitor of the nuclearfactor-kappaB pathway, ameliorates dextran sulfate sodium-inducedcolitis in mice. Int Immunopharmacol 2012;12:169-174.
    • (2012) Int Immunopharmacol , vol.12 , pp. 169-174
    • Zhao, Z.J.1    Xiang, J.Y.2    Liu, L.3
  • 14
    • 22244449287 scopus 로고    scopus 로고
    • Susceptibility of cholangiocarcinoma cellsto parthenolide-induced apoptosis
    • Kim JH, Liu L, Lee SO, et al. Susceptibility of cholangiocarcinoma cellsto parthenolide-induced apoptosis. Cancer Res 2005;65:6312-6320.
    • (2005) Cancer Res , vol.65 , pp. 6312-6320
    • Kim, J.H.1    Liu, L.2    Lee, S.O.3
  • 15
    • 6044240634 scopus 로고    scopus 로고
    • Antitumor agent parthenolidereverses resistance of breast cancer cells to tumor necrosis factorrelatedapoptosis-inducing ligand through sustained activation ofc-Jun N-terminal kinase
    • Nakshatri H, Rice SE, Bhat-Nakshatri P. Antitumor agent parthenolidereverses resistance of breast cancer cells to tumor necrosis factorrelatedapoptosis-inducing ligand through sustained activation ofc-Jun N-terminal kinase. Oncogene 2004;23:7330-7344.
    • (2004) Oncogene , vol.23 , pp. 7330-7344
    • Nakshatri, H.1    Rice, S.E.2    Bhat-Nakshatri, P.3
  • 16
    • 16844374151 scopus 로고    scopus 로고
    • Identification of the genes involved inenhanced fenretinide-induced apoptosis by parthenolide in humanhepatoma cells
    • Park JH, Liu L, Kim IH, et al. Identification of the genes involved inenhanced fenretinide-induced apoptosis by parthenolide in humanhepatoma cells. Cancer Res 2005;65:2804-2814.
    • (2005) Cancer Res , vol.65 , pp. 2804-2814
    • Park, J.H.1    Liu, L.2    Kim, I.H.3
  • 17
    • 58149359316 scopus 로고    scopus 로고
    • Effect of celecoxib and thenovel anti-cancer agent, dimethylamino- parthenolide, in a developmentalmodel of pancreatic cancer
    • Yip-Schneider MT, Wu H, Njoku V, et al. Effect of celecoxib and thenovel anti-cancer agent, dimethylamino-parthenolide, in a developmentalmodel of pancreatic cancer. Pancreas 2008;37:e45-e53.
    • (2008) Pancreas , vol.37
    • Yip-Schneider, M.T.1    Wu, H.2    Njoku, V.3
  • 18
    • 2442538125 scopus 로고    scopus 로고
    • Critical roles of intracellular thiols andcalcium in parthenolide-induced apoptosis in human colorectal cancercells
    • Zhang S, Ong CN, Shen HM. Critical roles of intracellular thiols andcalcium in parthenolide-induced apoptosis in human colorectal cancercells. Cancer Lett 2004;208:143-153.
    • (2004) Cancer Lett , vol.208 , pp. 143-153
    • Zhang, S.1    Ong, C.N.2    Shen, H.M.3
  • 19
    • 67650311657 scopus 로고    scopus 로고
    • Aminoparthenolides asnovel anti-leukemic agents: Discovery of the NF-kappaB inhibitor,DMAPT (LC-1)
    • Neelakantan S, Nasim S, Guzman ML, et al. Aminoparthenolides asnovel anti-leukemic agents: Discovery of the NF-kappaB inhibitor,DMAPT (LC-1). Bioorg Med Chem Lett 2009;19:4346-4349.
    • (2009) Bioorg Med Chem Lett , vol.19 , pp. 4346-4349
    • Neelakantan, S.1    Nasim, S.2    Guzman, M.L.3
  • 20
    • 84867822440 scopus 로고    scopus 로고
    • Guaianolide sesquiterpene lactones asource to discover agents that selectively inhibit acute myelogenousleukemia stem and progenitor cells
    • Zhang Q, Lu Y, Ding Y, et al. Guaianolide sesquiterpene lactones, asource to discover agents that selectively inhibit acute myelogenousleukemia stem and progenitor cells. J Med Chem 2012;55:8757-8769.
    • (2012) J Med Chem , vol.55 , pp. 8757-8769
    • Zhang, Q.1    Lu, Y.2    Ding, Y.3
  • 21
    • 77953371413 scopus 로고    scopus 로고
    • A water-solubleparthenolide analogue suppresses in vivo prostate cancer growth bytargeting NFkappaB and generating reactive oxygen species
    • Shanmugam R, Kusumanchi P, Cheng L, et al. A water-solubleparthenolide analogue suppresses in vivo prostate cancer growth bytargeting NFkappaB and generating reactive oxygen species. Prostate2010;70:1074-1086.
    • (2010) Prostate , vol.70 , pp. 1074-1086
    • Shanmugam, R.1    Kusumanchi, P.2    Cheng, L.3
  • 22
    • 79953212611 scopus 로고    scopus 로고
    • A water solubleparthenolide analog suppresses in vivo tumor growth of two tobaccoassociatedcancers, lung and bladder cancer, by targeting NF-kappaBand generating reactive oxygen species
    • Shanmugam R, Kusumanchi P, Appaiah H, et al. A water solubleparthenolide analog suppresses in vivo tumor growth of two tobaccoassociatedcancers, lung and bladder cancer, by targeting NF-kappaBand generating reactive oxygen species. Int J Cancer 2011;128:2481-2494.
    • (2011) Int J Cancer , vol.128 , pp. 2481-2494
    • Shanmugam, R.1    Kusumanchi, P.2    Appaiah, H.3
  • 23
    • 37349117583 scopus 로고    scopus 로고
    • The solution and solid state stabilityand excipient compatibility of parthenolide in feverfew
    • Jin P, Madieh S, Augsburger LL. The solution and solid state stabilityand excipient compatibility of parthenolide in feverfew. AAPS Pharm Sci Tech 2007;8:E105.
    • (2007) AAPS Pharm Sci Tech , vol.8
    • Jin, P.1    Madieh, S.2    Augsburger, L.L.3
  • 24
    • 84865256244 scopus 로고    scopus 로고
    • Biomimetic semisynthesis of arglabin fromparthenolide
    • Zhai JD, Li D, Long J, et al. Biomimetic semisynthesis of arglabin fromparthenolide. J Org Chem 2012;77:7103-7107.
    • (2012) J Org Chem , vol.77 , pp. 7103-7107
    • Zhai, J.D.1    Li, D.2    Long, J.3
  • 25
    • 84885953497 scopus 로고    scopus 로고
    • The application of Heck reaction in thesynthesis of guaianolide sesquiterpene lactones derivatives selectivelyinhibiting resistant acute leukemic cells
    • Ding YH, Fan HX, Long J, et al. The application of Heck reaction in thesynthesis of guaianolide sesquiterpene lactones derivatives selectivelyinhibiting resistant acute leukemic cells. Bioorg Med Chem Lett2013;23:6087-6092.
    • (2013) Bioorg Med Chem Lett , vol.23 , pp. 6087-6092
    • Ding, Y.H.1    Fan, H.X.2    Long, J.3
  • 26
    • 84878273883 scopus 로고    scopus 로고
    • Synthesis of micheliolide derivativesand their activities against AML progenitor cells
    • Ma WW, Shi QQ, Ding YH, et al. Synthesis of micheliolide derivativesand their activities against AML progenitor cells. Molecules 2013;18:5980-5992.
    • (2013) Molecules , vol.18 , pp. 5980-5992
    • Ma, W.W.1    Shi, Q.Q.2    Ding, Y.H.3
  • 27
    • 84883543003 scopus 로고    scopus 로고
    • Dextran sodium sulfate inhibits theactivities of both polymerase and reverse transcriptase: Lithiumchloride purification, a rapid and efficient technique to purify RNA
    • Viennois E, Chen F, Laroui H, et al. Dextran sodium sulfate inhibits theactivities of both polymerase and reverse transcriptase: Lithiumchloride purification, a rapid and efficient technique to purify RNA.BMC Res Notes 2013;6:360.
    • (2013) BMC Res Notes , vol.6 , pp. 360
    • Viennois, E.1    Chen, F.2    Laroui, H.3
  • 28
    • 12344264786 scopus 로고    scopus 로고
    • ADAM-15 inhibits wound healing inhuman intestinal epithelial cell monolayers
    • Charrier L, Yan Y, Driss A, et al. ADAM-15 inhibits wound healing inhuman intestinal epithelial cell monolayers. Am J Physiol GastrointestLiver Physiol 2005;288:G346-G353.
    • (2005) Am J Physiol GastrointestLiver Physiol , vol.288
    • Charrier, L.1    Yan, Y.2    Driss, A.3
  • 29
    • 84860704019 scopus 로고    scopus 로고
    • Gastrointestinal delivery of antiinflammatorynanoparticles
    • Laroui H, Sitaraman SV, Merlin D. Gastrointestinal delivery of antiinflammatorynanoparticles. Methods Enzymol 2012;509:101-125.
    • (2012) Methods Enzymol , vol.509 , pp. 101-125
    • Laroui, H.1    Sitaraman, S.V.2    Merlin, D.3
  • 30
    • 4043088499 scopus 로고    scopus 로고
    • IKKbeta links inflammation andtumorigenesis in a mouse model of colitis-associated cancer
    • Greten FR, Eckmann L, Greten TF, et al. IKKbeta links inflammation andtumorigenesis in a mouse model of colitis-associated cancer. Cell2004;118:285-296.
    • (2004) Cell , vol.118 , pp. 285-296
    • Greten, F.R.1    Eckmann, L.2    Greten, T.F.3
  • 31
    • 14644403009 scopus 로고    scopus 로고
    • Toll-like receptor 9-inducedtype i IFN protects mice from experimental colitis
    • Katakura K, Lee J, Rachmilewitz D, et al. Toll-like receptor 9-inducedtype I IFN protects mice from experimental colitis. J Clin Invest2005;115:695-702.
    • (2005) J Clin Invest , vol.115 , pp. 695-702
    • Katakura, K.1    Lee, J.2    Rachmilewitz, D.3
  • 32
    • 84866015194 scopus 로고    scopus 로고
    • Fecal lipocalin 2, asensitive and broadly dynamic non-invasive biomarker for intestinalinflammation
    • Chassaing B, Srinivasan G, Delgado MA, et al. Fecal lipocalin 2, asensitive and broadly dynamic non-invasive biomarker for intestinalinflammation. PLoS One 2012;7:e44328.
    • (2012) PLoS One , vol.7
    • Chassaing, B.1    Srinivasan, G.2    Delgado, M.A.3
  • 33
    • 0026410069 scopus 로고
    • Hyaluronan and wound healing: Anew perspective
    • Burd DA, Greco RM, Regauer S, et al. Hyaluronan and wound healing: Anew perspective. Br J Plast Surg 1991;44:579-584.
    • (1991) Br J Plast Surg , vol.44 , pp. 579-584
    • Burd, D.A.1    Greco, R.M.2    Regauer, S.3
  • 34
    • 0025775850 scopus 로고
    • The effect of capsulecomposition on the biocompatibility of alginate-poly-l-lysine capsules
    • Clayton HA, London NJ, Colloby PS, et al. The effect of capsulecomposition on the biocompatibility of alginate-poly-l-lysine capsules.J Microencapsul 1991;8:221-233.
    • (1991) J Microencapsul , vol.8 , pp. 221-233
    • Clayton, H.A.1    London, N.J.2    Colloby, P.S.3
  • 35
    • 77249111226 scopus 로고    scopus 로고
    • Drug-loaded nanoparticlestargeted to the colon with polysaccharide hydrogel reduce colitis in amouse model
    • e841-842
    • Laroui H, Dalmasso G, Nguyen HT, et al. Drug-loaded nanoparticlestargeted to the colon with polysaccharide hydrogel reduce colitis in amouse model. Gastroenterology 2010;138:843-853, e841-842.
    • (2010) Gastroenterology , vol.138 , pp. 843-853
    • Laroui, H.1    Dalmasso, G.2    Nguyen, H.T.3
  • 36
    • 33645302350 scopus 로고    scopus 로고
    • Crosslinked chitosan implants aspotential degradable devices for brachytherapy: In vitro and in vivoanalysis
    • Azab AK, Orkin B, Doviner V, et al. Crosslinked chitosan implants aspotential degradable devices for brachytherapy: In vitro and in vivoanalysis. J Control Release 2006;111:281-289.
    • (2006) J Control Release , vol.111 , pp. 281-289
    • Azab, A.K.1    Orkin, B.2    Doviner, V.3
  • 37
    • 0037130218 scopus 로고    scopus 로고
    • Chitosan capsules for colonspecificdrug delivery: Enhanced localization of 5-aminosalicylic acid inthe large intestine accelerates healing of TNBS-induced colitis in rats
    • Tozaki H, Odoriba T, Okada N, et al. Chitosan capsules for colonspecificdrug delivery: Enhanced localization of 5-aminosalicylic acid inthe large intestine accelerates healing of TNBS-induced colitis in rats.J Control Release 2002;82:51-61.
    • (2002) J Control Release , vol.82 , pp. 51-61
    • Tozaki, H.1    Odoriba, T.2    Okada, N.3
  • 38
    • 34547858901 scopus 로고    scopus 로고
    • Colon-specific delivery of5-aminosalicylic acid from chitosan-Ca-alginate microparticles
    • Mladenovska K, Raicki RS, Janevik EI, et al. Colon-specific delivery of5-aminosalicylic acid from chitosan-Ca-alginate microparticles. Int J Pharm 2007;342:124-136.
    • (2007) Int J Pharm , vol.342 , pp. 124-136
    • Mladenovska, K.1    Raicki, R.S.2    Janevik, E.I.3
  • 39
    • 33646886609 scopus 로고    scopus 로고
    • Therapeutic potential of chitosanand its derivatives in regenerative medicine
    • Shi C, Zhu Y, Ran X, et al. Therapeutic potential of chitosanand its derivatives in regenerative medicine. J Surg Res 2006;133:185-192.
    • (2006) J Surg Res , vol.133 , pp. 185-192
    • Shi, C.1    Zhu, Y.2    Ran, X.3
  • 40
    • 0034005581 scopus 로고    scopus 로고
    • Role of cytokines in the pathogenesis ofinflammatory bowel disease
    • Papadakis KA, Targan SR. Role of cytokines in the pathogenesis ofinflammatory bowel disease. Annu Rev Med 2000;51:289-298.
    • (2000) Annu Rev Med , vol.51 , pp. 289-298
    • Papadakis, K.A.1    Targan, S.R.2
  • 41
    • 0034956578 scopus 로고    scopus 로고
    • Tumor necrosis factor-alpha inserum of patients with inflammatory bowel disease as measured by ahighly sensitive immuno-PCR
    • Komatsu M, Kobayashi D, Saito K, et al. Tumor necrosis factor-alpha inserum of patients with inflammatory bowel disease as measured by ahighly sensitive immuno-PCR. Clin Chem 2001;47:1297-1301.
    • (2001) Clin Chem , vol.47 , pp. 1297-1301
    • Komatsu, M.1    Kobayashi, D.2    Saito, K.3
  • 42
    • 0026689516 scopus 로고
    • Tumor necrosis factor-alpha,interleukin-1 beta, and interleukin-6 expression in inflammatory boweldisease
    • Stevens C, Walz G, Singaram C, et al. Tumor necrosis factor-alpha, interleukin-1 beta, and interleukin-6 expression in inflammatory boweldisease. Dig Dis Sci 1992;37:818-826.
    • (1992) Dig Dis Sci , vol.37 , pp. 818-826
    • Stevens, C.1    Walz, G.2    Singaram, C.3
  • 43
    • 16244410786 scopus 로고    scopus 로고
    • Tumor necrosis factor family members and inflammatorybowel disease
    • Wang J, Fu YX. Tumor necrosis factor family members and inflammatorybowel disease. Immunol Rev 2005;204:144-155.
    • (2005) Immunol Rev , vol.204 , pp. 144-155
    • Wang, J.1    Fu, Y.X.2
  • 44
    • 0034727474 scopus 로고    scopus 로고
    • Mechanisms in failure ofinfliximab for Crohn's disease
    • Nikolaus S, Raedler A, Kuhbacker T, et al. Mechanisms in failure ofinfliximab for Crohn's disease. Lancet 2000;356:1475-1479.
    • (2000) Lancet , vol.356 , pp. 1475-1479
    • Nikolaus, S.1    Raedler, A.2    Kuhbacker, T.3
  • 45
    • 2442560241 scopus 로고    scopus 로고
    • Optimizing anti-TNF treatmentin inflammatory bowel disease
    • Rutgeerts P, Van Assche G, Vermeire S. Optimizing anti-TNF treatmentin inflammatory bowel disease. Gastroenterology 2004;126:1593-1610.
    • (2004) Gastroenterology , vol.126 , pp. 1593-1610
    • Rutgeerts, P.1    Van Assche, G.2    Vermeire, S.3
  • 46
    • 79951650570 scopus 로고    scopus 로고
    • Cancer in Crohn's Diseasepatients treated with infliximab: A long-term multicenter matched pairstudy
    • Biancone L, Petruzziello C, Orlando A, et al. Cancer in Crohn's Diseasepatients treated with infliximab: A long-term multicenter matched pairstudy. Inflamm Bowel Dis 2011;17:758-766.
    • (2011) Inflamm Bowel Dis , vol.17 , pp. 758-766
    • Biancone, L.1    Petruzziello, C.2    Orlando, A.3
  • 47
    • 3543106683 scopus 로고    scopus 로고
    • Human antichimeric antibodyin children and young adults with inflammatory bowel diseasereceiving infliximab
    • Miele E, Markowitz JE, Mamula P, et al. Human antichimeric antibodyin children and young adults with inflammatory bowel diseasereceiving infliximab. J Pediatr Gastroenterol Nutr 2004;38:502-508.
    • (2004) J Pediatr Gastroenterol Nutr , vol.38 , pp. 502-508
    • Miele, E.1    Markowitz, J.E.2    Mamula, P.3
  • 49
    • 67650430007 scopus 로고    scopus 로고
    • Infliximab and otherimmunomodulating drugs in patients with inflammatory boweldisease and the risk of serious bacterial infections
    • Schneeweiss S, Korzenik J, Solomon DH, et al. Infliximab and otherimmunomodulating drugs in patients with inflammatory boweldisease and the risk of serious bacterial infections. AlimentPharmacol Ther 2009;30:253-264.
    • (2009) AlimentPharmacol Ther , vol.30 , pp. 253-264
    • Schneeweiss, S.1    Korzenik, J.2    Solomon, D.H.3
  • 50
    • 78651327288 scopus 로고    scopus 로고
    • Severe neutropenia followinginfliximab treatment in a child with ulcerative colitis
    • Sherlock ME, Bandsma R, Ota K, et al. Severe neutropenia followinginfliximab treatment in a child with ulcerative colitis. Inflamm Bowel Dis 2011;17:E17-E18.
    • (2011) Inflamm Bowel Dis , vol.17
    • Sherlock, M.E.1    Bandsma, R.2    Ota, K.3
  • 51
    • 79958095982 scopus 로고    scopus 로고
    • Severe infusion reactions toinfliximab: Aetiology, immunogenicity and risk factors in patients withinflammatory bowel disease
    • Steenholdt C, Svenson M, Bendtzen K, et al. Severe infusion reactions toinfliximab: Aetiology, immunogenicity and risk factors in patients withinflammatory bowel disease. Aliment Pharmacol Ther 2011;34:51-58.
    • (2011) Aliment Pharmacol Ther , vol.34 , pp. 51-58
    • Steenholdt, C.1    Svenson, M.2    Bendtzen, K.3
  • 52
    • 84861333218 scopus 로고    scopus 로고
    • Risk of infection andprevention in pediatric patients with IBD: ESPGHAN IBD Porto Groupcommentary
    • Veereman-Wauters G, de Ridder L, Veres G, et al. Risk of infection andprevention in pediatric patients with IBD: ESPGHAN IBD Porto Groupcommentary. J Pediatr Gastroenterol Nutr 2012;54:830-837.
    • (2012) J Pediatr Gastroenterol Nutr , vol.54 , pp. 830-837
    • Veereman-Wauters, G.1    De Ridder, L.2    Veres, G.3
  • 53
    • 79953099459 scopus 로고    scopus 로고
    • Infliximab and adalimumabinducedpsoriasis in Crohn's disease: A paradoxical side effect
    • Iborra M, Beltran B, Bastida G, et al. Infliximab and adalimumabinducedpsoriasis in Crohn's disease: A paradoxical side effect. J CrohnsColitis 2011;5:157-161.
    • (2011) J CrohnsColitis , vol.5 , pp. 157-161
    • Iborra, M.1    Beltran, B.2    Bastida, G.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.