Genetic evidence for a normal-weight "metabolically obese" phenotype linking insulin resistance, hypertension, coronary artery disease, and type 2 diabetes

Diabetes

Volumn 63, Issue 12, 2014, Pages 4369-4377

  Yaghootkar, Hanieh ^a   Scott, Robert A ^b   White, Charles C ^c,d   Zhang, Weihua ^e   Speliotes, Elizabeth ^f   Munroe, Patricia B ^g   Ehret, Georg B ^h,i   Bis, Joshua C ^j   Fox, Caroline S ^c,k   Walker, Mark ^l   Borecki, Ingrid B ^m   Knowles, Joshua W ⁿ   Yerges Armstrong, Laura ^o   Ohlsson, Claes ^p   Perry, John R B ^b   Chambers, John C ^e   Kooner, Jaspal S ^q   Franceschini, Nora ^r   Langenberg, Claudia ^b,s   Hivert, Marie France ^k,t   Dastani, Zari ^u   Richards, J Brent ^u,v   Semple, Robert K ^w,x   Frayling, Timothy M ^a   more..

^a UNIVERSITY OF EXETER MEDICAL SCHOOL   (United Kingdom)

^b INSTITUTE OF METABOLIC SCIENCE   (United Kingdom)

^c NATIONAL HEART LUNG AND BLOOD INSTITUTE   (United States)

^d BOSTON UNIVERSITY SCHOOL OF PUBLIC HEALTH   (United States)

^e IMPERIAL COLLEGE LONDON   (United Kingdom)

^f UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^g QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

^h Canton Hospital of the University of Geneva   (Switzerland)

ⁱ JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^j UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^k HARVARD MEDICAL SCHOOL   (United States)

^l NEWCASTLE UNIVERSITY   (United Kingdom)

^m WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

ⁿ STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^o UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

^p UNIVERSITY OF GOTHENBURG   (Sweden)

^q NATIONAL HEART AND LUNG INSTITUTE   (United Kingdom)

^r IL   (United States)

^s UNIVERSITY COLLEGE LONDON   (United Kingdom)

^t MASSACHUSETTS GENERAL HOSPITAL   (United States)

^u MCGILL UNIVERSITY   (Canada)

^v KING'S COLLEGE LONDON   (United Kingdom)

^w NONE   (United Kingdom)

^x UNIVERSITY OF CAMBRIDGE   (United Kingdom)

more..

Author keywords

[No Author keywords available]

Indexed keywords

ADIPONECTIN; ALANINE AMINOTRANSFERASE; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; INSULIN; SEX HORMONE BINDING GLOBULIN; SOMATOMEDIN C; TRANSCRIPTION FACTOR 7 LIKE 2; TRIACYLGLYCEROL;

ALLELE; ARTICLE; CONTROLLED STUDY; CORONARY ARTERY DISEASE; DIASTOLIC BLOOD PRESSURE; ELEVATED BLOOD PRESSURE; FATTY LIVER; FTO GENE; GCKR GENE; GENETIC ASSOCIATION; GENETIC PREDISPOSITION; GENETIC RISK; GENETIC VARIABILITY; GLUCOSE METABOLISM; HIP1 GENE; HUMAN; HYPERTENSION; INSULIN RESISTANCE; INTRAABDOMINAL FAT; LIPID METABOLISM; LIPODYSTROPHY; MAJOR CLINICAL STUDY; METABOLICALLY OBESE; NON INSULIN DEPENDENT DIABETES MELLITUS; OBESITY; OUTCOME ASSESSMENT; PHENOTYPE; PPP1R3B GENE; SINGLE NUCLEOTIDE POLYMORPHISM; SOMATOMEDIN C GENE; SUBCUTANEOUS FAT; SYSTOLIC BLOOD PRESSURE; TRANSCRIPTION FACTOR 7 LIKE 2 GENE; UKRF1BP1 GENE; YSK4 GENE; BODY MASS; GENETICS; METABOLIC SYNDROME X; ODDS RATIO;

BODY MASS INDEX; CORONARY ARTERY DISEASE; DIABETES MELLITUS, TYPE 2; GENETIC PREDISPOSITION TO DISEASE; HUMANS; HYPERTENSION; INSULIN RESISTANCE; INTRA-ABDOMINAL FAT; LIPODYSTROPHY; METABOLIC SYNDROME X; OBESITY; ODDS RATIO; PHENOTYPE; SUBCUTANEOUS FAT;

EID: 84906824359     PISSN: 00121797     EISSN: 1939327X     Source Type: Journal    
DOI: 10.2337/db14-0318     Document Type: Article

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