Metabolic insights from extreme human insulin resistance phenotypes

Best Practice and Research: Clinical Endocrinology and Metabolism

Volumn 26, Issue 2, 2012, Pages 145-157

  Stears, Anna ^a   O'Rahilly, Stephen ^a   Semple, Robert K ^a   Savage, David B ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

adiponectin; fatty liver; insulin resistance; metabolic syndrome; mitochondria

Indexed keywords

ADENOSINE TRIPHOSPHATE; ADIPONECTIN; CHYLOMICRON; FATTY ACID; GLUCOSE; GLYCOGEN SYNTHASE KINASE 3ALPHA; GROWTH FACTOR RECEPTOR BOUND PROTEIN 2; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; INSULIN; INSULIN RECEPTOR; LEPTIN; LOW DENSITY LIPOPROTEIN; MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 1; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; SEX HORMONE BINDING GLOBULIN; SOMATOMEDIN BINDING PROTEIN 1; STEROL REGULATORY ELEMENT BINDING PROTEIN 1C; TRANSCRIPTION FACTOR FKHR; TRIACYLGLYCEROL;

ACANTHOSIS NIGRICANS; APOPTOSIS; ARTICLE; CARDIOVASCULAR RISK; CLINICAL FEATURE; DISEASE SEVERITY; DYSLIPIDEMIA; FAMILIAL PARTIAL LIPODYSTROPHY; FATTY LIVER; GENE MUTATION; GLUCOGENESIS; GLUCONEOGENESIS; GLUCOSE BLOOD LEVEL; GLUCOSE INTOLERANCE; GLYCOGEN SYNTHESIS; HUMAN; HYPERGLYCEMIA; HYPERTENSION; HYPERTRICHOSIS; INSULIN BLOOD LEVEL; INSULIN RESISTANCE; LEPRECHAUNISM; LIPODYSTROPHY; LIPOLYSIS; LIVER CELL; LIVER CELL CARCINOMA; LIVER CIRRHOSIS; LIVER FUNCTION TEST; METABOLIC PARAMETERS; METABOLIC SYNDROME X; MOLECULAR PATHOLOGY; NON INSULIN DEPENDENT DIABETES MELLITUS; NONALCOHOLIC FATTY LIVER; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; OBESITY; OVARY POLYCYSTIC DISEASE; PATHOGENESIS; PATHOPHYSIOLOGY; PHENOTYPE; PHOSPHORUS NUCLEAR MAGNETIC RESONANCE; PREVALENCE; PROTEIN SYNTHESIS; SIGNAL TRANSDUCTION; TRIACYLGLYCEROL BLOOD LEVEL;

EID: 84859576586     PISSN: 1521690X     EISSN: 15321908     Source Type: Journal    
DOI: 10.1016/j.beem.2011.09.003     Document Type: Review

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