Common genetic variants highlight the role of insulin resistance and body fat distribution in type 2 diabetes, independent of obesity

Diabetes

Volumn 63, Issue 12, 2014, Pages 4378-4387

  Scott, Robert A ^a   Fall, Tove ^b   Pasko, Dorota ^c   Barker, Adam ^a   Sharp, Stephen J ^a   Arriola, Larraitz ^d,e,f   Balkau, Beverley ^g,h   Barricarte, Aurelio ^f,i   Barroso, Inês ^j,k   Boeing, Heiner ^l   Clavel Chapelon, Franҫoise ^g,h   Crowe, Francesca L ^m   Dekker, Jacqueline M ⁿ   Fagherazzi, Guy ^g,h   Ferrannini, Ele ^o   Forouhi, Nita G ^a   Franks, Paul W ^p,q   Gavrila, Diana ^f,r   Giedraitis, Vilmantas ^s   Grioni, Sara ^t   Groop, Leif C ^u,v   Kaaks, Rudolf ^w   Key, Timothy J ^m   Kühn, Tilman ^w   Lotta, Luca A ^a   Nilsson, Peter M ^p   Overvad, Kim ^x,y   Palli, Domenico ^z   Panico, Salvatore ^aa   Ramon Quiros J ^ab   Rolandsson, Olov ^q   Roswall, Nina ^ac   Sacerdote, Carlotta ^ad,ae   Sala, Núria ^af   Sánchez, María José ^f,ag,ah   Schulze, Matthias B ^l   Siddiq, Afshan ^ai   Slimani, Nadia ^aj   Sluijs, Ivonne ^ak   Spijkerman, Annemieke M W ^al   Tjonneland, Anne ^ac   Tumino, Rosario ^am,an   Van Der A, Daphne L ^al   Yaghootkar, Hanieh ^c   McCarthy, Mark I ^ao,ap,aq   Semple, Robert K ^k   Riboli, Elio ^ai   Walker, Mark ^ar   Ingelsson, Erik ^b   Frayling, Tim M ^c   Savage, David B ^k   Langenberg, Claudia ^a   Wareham, Nicholas J ^a   more..

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b UPPSALA UNIVERSITY   (Sweden)

^c UNIVERSITY OF EXETER MEDICAL SCHOOL   (United Kingdom)

^d Basque Government   (Spain)

^e BIODONOSTIA HEALTH RESEARCH INSTITUTE   (Spain)

^f CIBER EPIDEMIOLOGÍA Y SALUD PÚBLICA CIBERESP   (Spain)

^g CENTRE FOR RESEARCH IN EPIDEMIOLOGY AND POPULATION HEALTH   (France)

^h UNIVERSITÉ PARIS SACLAY   (France)

ⁱ INSTITUTO DE SALUD PÚBLICA DE NAVARRA   (Spain)

^j WELLCOME TRUST SANGER INSTITUTE   (United Kingdom)

^k UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^l GERMAN INSTITUTE OF HUMAN NUTRITION   (Germany)

^m UNIVERSITY OF OXFORD   (United Kingdom)

ⁿ VU UNIVERSITY MEDICAL CENTER   (Netherlands)

^o UNIVERSITY OF PISA   (Italy)

^p LUND UNIVERSITY   (Sweden)

^q UMEÅ UNIVERSITY   (Sweden)

^r DEPARTMENT OF EPIDEMIOLOGY   (Spain)

^s UPPSALA UNIVERSITY   (Sweden)

^t Epidemiology Unit   (Italy)

^u LUND UNIVERSITY HOSPITAL   (Sweden)

^v UNIVERSITY OF HELSINKI   (Finland)

^w GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^x AARHUS UNIVERSITY   (Denmark)

^y AALBORG UNIVERSITY HOSPITAL   (Denmark)

^z CANCER RESEARCH AND PREVENTION INSTITUTE ISPO   (Italy)

^aa UNIVERSITY OF NAPLES FEDERICO II   (Italy)

^ab Public Health Directorate   (Spain)

^ac DANISH CANCER SOCIETY RESEARCH CENTER   (Denmark)

^ad UNIVERSITY OF TURIN   (Italy)

^ae Human Genetics Foundation   (Italy)

^af CATALAN INSTITUTE OF ONCOLOGY   (Spain)

^ag ANDALUSIAN SCHOOL OF PUBLIC HEALTH   (Spain)

^ah Instituto de Investigación Biosanitaria de Granada   (Spain)

^ai IMPERIAL COLLEGE LONDON   (United Kingdom)

^aj INTERNATIONAL AGENCY FOR RESEARCH ON CANCER   (France)

^ak UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^al NATIONAL INSTITUTE FOR PUBLIC HEALTH AND THE ENVIRONMENT   (Netherlands)

^am Azienda sanitaria provinciale (ASP)   (Italy)

^an Aire Onlus   (Italy)

^ao UNIVERSITY OF OXFORD   (United Kingdom)

^ap UNIVERSITY OF OXFORD   (United Kingdom)

^aq NIHR OXFORD BIOMEDICAL RESEARCH CENTRE   (United Kingdom)

^ar NEWCASTLE UNIVERSITY   (United Kingdom)

more..

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE AMINOTRANSFERASE; GAMMA GLUTAMYLTRANSFERASE; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; INSULIN; TRIACYLGLYCEROL;

ADULT; AGED; ALANINE AMINOTRANSFERASE BLOOD LEVEL; ALCOHOL CONSUMPTION; ARTICLE; BODY FAT DISTRIBUTION; BODY MASS; COHORT ANALYSIS; FAT MASS; FEMALE; GAMMA GLUTAMYL TRANSFERASE BLOOD LEVEL; GENETIC RISK; GENETIC VARIABILITY; GLUCOSE BLOOD LEVEL; HIP CIRCUMFERENCE; HUMAN; INSULIN BLOOD LEVEL; INSULIN RELEASE; INSULIN RESISTANCE; INSULIN SENSITIVITY; MAJOR CLINICAL STUDY; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; OBESITY; ORAL GLUCOSE TOLERANCE TEST; PHENOTYPE; STATISTICAL SIGNIFICANCE; TRIACYLGLYCEROL BLOOD LEVEL; VALIDATION STUDY; WAIST CIRCUMFERENCE; BODY COMPOSITION; GENETIC PREDISPOSITION; GENETICS; GLUCOSE CLAMP TECHNIQUE; GLUCOSE TOLERANCE TEST; METABOLISM; MIDDLE AGED; SECRETION (PROCESS); SINGLE NUCLEOTIDE POLYMORPHISM;

ADULT; AGED; ALANINE TRANSAMINASE; BODY COMPOSITION; BODY FAT DISTRIBUTION; BODY MASS INDEX; COHORT STUDIES; DIABETES MELLITUS, TYPE 2; FEMALE; GAMMA-GLUTAMYLTRANSFERASE; GENETIC PREDISPOSITION TO DISEASE; GENETIC VARIATION; GLUCOSE CLAMP TECHNIQUE; GLUCOSE TOLERANCE TEST; HUMANS; INSULIN; INSULIN RESISTANCE; MALE; MIDDLE AGED; OBESITY; OVERWEIGHT; POLYMORPHISM, SINGLE NUCLEOTIDE; WAIST CIRCUMFERENCE;

EID: 84911949202     PISSN: 00121797     EISSN: 1939327X     Source Type: Journal    
DOI: 10.2337/db14-0319     Document Type: Article

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