Inheritance of rare functional GCKR variants and their contribution to triglyceride levels in families

Human Molecular Genetics

Volumn 23, Issue 20, 2014, Pages 5570-5578

  Rees, Matthew G ^a,b,c   Raimondo, Anne ^a   Wang, Jian ^d   Ban, Matthew R ^d   Davis, Mindy I ^c   Barrett, Amy ^a   Ranft, Jessica ^e   Jagdhuhn, David ^e   Waterstradt, Rica ^e   Baltrusch, Simone ^e   Simeonov, Anton ^c   Collins, Francis S ^b   Hegele, Robert A ^d   Gloyn, Anna L ^a,f  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b NATIONAL HUMAN GENOME RESEARCH INSTITUTE   (United States)

^c NATIONAL INSTITUTES OF HEALTH   (United States)

^d ROBARTS RESEARCH INSTITUTE   (Canada)

^e UNIVERSITY OF ROSTOCK   (Germany)

^f CHURCHILL HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOKINASE; GLUCOKINASE REGULATORY PROTEIN; PROTEIN VARIANT; REGULATOR PROTEIN; TRIACYLGLYCEROL; UNCLASSIFIED DRUG; GCKR PROTEIN, HUMAN; SIGNAL TRANSDUCING ADAPTOR PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BIOASSAY; BIOCHEMICAL ANALYSIS; BIOCHEMISTRY; COMPUTER MODEL; CONTROLLED STUDY; FEMALE; GENE FUNCTION; GENE IDENTIFICATION; GENE SEQUENCE; GENETIC ALGORITHM; GENETIC VARIABILITY; HELA CELL LINE; HERITABILITY; HIGH THROUGHPUT SCREENING; HUMAN; HYPERTRIGLYCERIDEMIA; INHERITANCE; MAJOR CLINICAL STUDY; MOUSE; NONHUMAN; PREDICTIVE VALUE; PRIORITY JOURNAL; TRIACYLGLYCEROL BLOOD LEVEL; ALGORITHM; ANIMAL; BLOOD; CASE CONTROL STUDY; CHEMICAL STRUCTURE; CHEMISTRY; CHLOROCEBUS AETHIOPS; COS 1 CELL LINE; DNA SEQUENCE; GENETICS; HYPERLIPOPROTEINEMIA TYPE 4; METABOLISM; PROTEIN TERTIARY STRUCTURE; SINGLE NUCLEOTIDE POLYMORPHISM;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ALGORITHMS; ANIMALS; CASE-CONTROL STUDIES; CERCOPITHECUS AETHIOPS; COS CELLS; GENETIC VARIATION; HELA CELLS; HUMANS; HYPERLIPOPROTEINEMIA TYPE IV; MICE; MODELS, MOLECULAR; POLYMORPHISM, SINGLE NUCLEOTIDE; PROTEIN STRUCTURE, TERTIARY; SEQUENCE ANALYSIS, DNA; TRIGLYCERIDES;

EID: 84911861463     PISSN: 09646906     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/ddu269     Document Type: Article

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