메뉴 건너뛰기




Volumn 15, Issue 9, 2014, Pages 14949-14966

Pomegranate and its components as alternative treatment for prostate cancer

Author keywords

Ellagic acid; Luteolin; Metastasis; Natural products; Punicic acid

Indexed keywords

PLANT EXTRACT;

EID: 84906823753     PISSN: 16616596     EISSN: 14220067     Source Type: Journal    
DOI: 10.3390/ijms150914949     Document Type: Review
Times cited : (62)

References (105)
  • 1
    • 84906822869 scopus 로고    scopus 로고
    • American Cancer Society. Available online: http://www.cancer.org/ (accessed on 1 July 2014).
  • 2
    • 77950616881 scopus 로고    scopus 로고
    • Targeted therapeutic approaches for hormone-refractory prostate cancer
    • Stavridi, F.; Karapanagiotou, E.M.; Syrigos, K.N. Targeted therapeutic approaches for hormone-refractory prostate cancer. Cancer Treat. Rev. 2010, 36, 122-130
    • (2010) Cancer Treat. Rev , vol.36 , pp. 122-130
    • Stavridi, F.1    Karapanagiotou, E.M.2    Syrigos, K.N.3
  • 4
    • 84879445790 scopus 로고    scopus 로고
    • Chemotherapy and targeted therapies: Are we making progress in castrate-resistant prostate cancer?
    • Hoffman-Censits, J.; Fu, M. Chemotherapy and targeted therapies: Are we making progress in castrate-resistant prostate cancer? Semin. Oncol. 2013, 40, 361-374
    • (2013) Semin. Oncol , vol.40 , pp. 361-374
    • Hoffman-Censits, J.1    Fu, M.2
  • 6
    • 84871624121 scopus 로고    scopus 로고
    • Abiraterone and its place in the treatment of metastatic crpc
    • Sartor, O.; Pal, S.K. Abiraterone and its place in the treatment of metastatic crpc. Nat. Rev. Clin. Oncol. 2013, 10, 6-8
    • (2013) Nat. Rev. Clin. Oncol , vol.10 , pp. 6-8
    • Sartor, O.1    Pal, S.K.2
  • 8
    • 83355166909 scopus 로고    scopus 로고
    • Cabozantinib (xl184), a novel met and vegfr2 inhibitor, simultaneously suppresses metastasis, angiogenesis, and tumor growth
    • Yakes, F.M.; Chen, J.; Tan, J.; Yamaguchi, K.; Shi, Y.; Yu, P.; Qian, F.; Chu, F.; Bentzien, F.; Cancilla, B., et al. Cabozantinib (xl184), a novel met and vegfr2 inhibitor, simultaneously suppresses metastasis, angiogenesis, and tumor growth. Mol. Cancer Ther. 2011, 10, 2298-2308
    • (2011) Mol. Cancer Ther , vol.10 , pp. 2298-2308
    • Yakes, F.M.1    Chen, J.2    Tan, J.3    Yamaguchi, K.4    Shi, Y.5    Yu, P.6    Qian, F.7    Chu, F.8    Bentzien, F.9    Cancilla, B.10
  • 10
    • 0037420189 scopus 로고    scopus 로고
    • The pomegranate: Nature's power fruit?
    • Longtin, R. The pomegranate: Nature's power fruit? J. Natl. Cancer Inst. 2003, 95, 346-348
    • (2003) J. Natl. Cancer Inst , vol.95 , pp. 346-348
    • Longtin, R.1
  • 11
    • 0034605755 scopus 로고    scopus 로고
    • Why a pomegranate?
    • Langley, P. Why a pomegranate? BMJ 2000, 321, 1153-1154
    • (2000) BMJ , vol.321 , pp. 1153-1154
    • Langley, P.1
  • 12
    • 0033788223 scopus 로고    scopus 로고
    • Antioxidant activity of pomegranate juice and its relationship with phenolic composition and processing
    • Gil, M.I.; Tomas-Barberan, F.A.; Hess-Pierce, B.; Holcroft, D.M.; Kader, A.A. Antioxidant activity of pomegranate juice and its relationship with phenolic composition and processing. J. Agric. Food Chem. 2000, 48, 4581-4589
    • (2000) J. Agric. Food Chem , vol.48 , pp. 4581-4589
    • Gil, M.I.1    Tomas-Barberan, F.A.2    Hess-Pierce, B.3    Holcroft, D.M.4    Kader, A.A.5
  • 13
    • 33845602057 scopus 로고    scopus 로고
    • Punica granatum (pomegranate) and its potential for prevention and treatment of inflammation and cancer
    • Lansky, E.P.; Newman, R.A. Punica granatum (pomegranate) and its potential for prevention and treatment of inflammation and cancer. J. Ethnopharmacol. 2007, 109, 177-206
    • (2007) J. Ethnopharmacol , vol.109 , pp. 177-206
    • Lansky, E.P.1    Newman, R.A.2
  • 15
    • 38349000628 scopus 로고    scopus 로고
    • Cancer chemoprevention through dietary antioxidants: Progress and promise
    • Khan, N.; Afaq, F.; Mukhtar, H. Cancer chemoprevention through dietary antioxidants: Progress and promise. Antioxid. Redox Signal. 2008, 10, 475-510
    • (2008) Antioxid. Redox Signal , vol.10 , pp. 475-510
    • Khan, N.1    Afaq, F.2    Mukhtar, H.3
  • 16
    • 0036006635 scopus 로고    scopus 로고
    • Antioxidant activities of pomegranate fruit extract and its anthocyanidins: Delphinidin, cyanidin, and pelargonidin
    • Noda, Y.; Kaneyuki, T.; Mori, A.; Packer, L. Antioxidant activities of pomegranate fruit extract and its anthocyanidins: Delphinidin, cyanidin, and pelargonidin. J. Agric. Food Chem. 2002, 50, 166-171
    • (2002) J. Agric. Food Chem , vol.50 , pp. 166-171
    • Noda, Y.1    Kaneyuki, T.2    Mori, A.3    Packer, L.4
  • 19
    • 17044414424 scopus 로고    scopus 로고
    • New insights into cyclins, cdks, and cell cycle control
    • Sanchez, I.; Dynlacht, B.D. New insights into cyclins, cdks, and cell cycle control. Semin. Cell Dev. Biol. 2005, 16, 311-321
    • (2005) Semin. Cell Dev. Biol , vol.16 , pp. 311-321
    • Sanchez, I.1    Dynlacht, B.D.2
  • 20
    • 0027496935 scopus 로고
    • The p21 cdk-interacting protein cip1 is a potent inhibitor of g1 cyclin-dependent kinases
    • Harper, J.W.; Adami, G.R.; Wei, N.; Keyomarsi, K.; Elledge, S.J. The p21 cdk-interacting protein cip1 is a potent inhibitor of g1 cyclin-dependent kinases. Cell 1993, 75, 805-816
    • (1993) Cell , vol.75 , pp. 805-816
    • Harper, J.W.1    Adami, G.R.2    Wei, N.3    Keyomarsi, K.4    Elledge, S.J.5
  • 21
    • 33645243020 scopus 로고    scopus 로고
    • Prostate cancer prevention through pomegranate fruit
    • Malik, A.; Mukhtar, H. Prostate cancer prevention through pomegranate fruit. Cell Cycle 2006, 5, 371-373
    • (2006) Cell Cycle , vol.5 , pp. 371-373
    • Malik, A.1    Mukhtar, H.2
  • 23
    • 79959975747 scopus 로고    scopus 로고
    • Cellular and molecular mechanisms of pomegranate juice-induced anti-metastatic effect on prostate cancer cells
    • Wang, L.; Alcon, A.; Yuan, H.; Ho, J.; Li, Q.J.; Martins-Green, M. Cellular and molecular mechanisms of pomegranate juice-induced anti-metastatic effect on prostate cancer cells. Integr. Biol. 2011, 3, 742-754
    • (2011) Integr. Biol , vol.3 , pp. 742-754
    • Wang, L.1    Alcon, A.2    Yuan, H.3    Ho, J.4    Li, Q.J.5    Martins-Green, M.6
  • 24
    • 53249094494 scopus 로고    scopus 로고
    • Pomegranate polyphenols down-regulate expression of androgen-synthesizing genes in human prostate cancer cells overexpressing the androgen receptor
    • Hong, M.Y.; Seeram, N.P.; Heber, D. Pomegranate polyphenols down-regulate expression of androgen-synthesizing genes in human prostate cancer cells overexpressing the androgen receptor. J. Nutr. Biochem. 2008, 19, 848-855
    • (2008) J. Nutr. Biochem , vol.19 , pp. 848-855
    • Hong, M.Y.1    Seeram, N.P.2    Heber, D.3
  • 26
  • 28
    • 84906066762 scopus 로고    scopus 로고
    • Beyond androgen deprivation: Ancillary integrative strategies for targeting the androgen receptor addiction of prostate cancer
    • doi:10.1177/1534735414534728
    • McCarty, M.F.; Hejazi, J.; Rastmanesh, R. Beyond androgen deprivation: Ancillary integrative strategies for targeting the androgen receptor addiction of prostate cancer. Integr. Cancer Ther. 2014, doi:10.1177/1534735414534728
    • (2014) Integr. Cancer Ther
    • McCarty, M.F.1    Hejazi, J.2    Rastmanesh, R.3
  • 29
    • 84857949057 scopus 로고    scopus 로고
    • Oral infusion of pomegranate fruit extract inhibits prostate carcinogenesis in the tramp model
    • Adhami, V.M.; Siddiqui, I.A.; Syed, D.N.; Lall, R.K.; Mukhtar, H. Oral infusion of pomegranate fruit extract inhibits prostate carcinogenesis in the tramp model. Carcinogenesis 2012, 33, 644-651
    • (2012) Carcinogenesis , vol.33 , pp. 644-651
    • Adhami, V.M.1    Siddiqui, I.A.2    Syed, D.N.3    Lall, R.K.4    Mukhtar, H.5
  • 31
    • 0019566535 scopus 로고
    • Prostaglandins and cancer a review of tumor initiation through tumor metastasis
    • Honn, K.V.; Bockman, R.S.; Marnett, L.J. Prostaglandins and cancer a review of tumor initiation through tumor metastasis. Prostaglandins 1981, 21, 833-864
    • (1981) Prostaglandins , vol.21 , pp. 833-864
    • Honn, K.V.1    Bockman, R.S.2    Marnett, L.J.3
  • 32
    • 0026356575 scopus 로고
    • Essential fatty acid distribution in the plasma and tissue phospholipids of patients with benign and malignant prostatic disease
    • Chaudry, A.; McClinton, S.; Moffat, L.E.F.; Wahle, K.W.J. Essential fatty acid distribution in the plasma and tissue phospholipids of patients with benign and malignant prostatic disease. Br. J. Cancer 1991, 64, 1157-1160
    • (1991) Br. J. Cancer , vol.64 , pp. 1157-1160
    • Chaudry, A.1    McClinton, S.2    Moffat, L.E.F.3    Wahle, K.W.J.4
  • 33
    • 67349091428 scopus 로고    scopus 로고
    • Inhibition of arachidonic acid metabolism and its implication on cell proliferation and tumour-angiogenesis
    • Hyde, C.A.; Missailidis, S. Inhibition of arachidonic acid metabolism and its implication on cell proliferation and tumour-angiogenesis. Int. Immunopharmacol. 2009, 9, 701-715
    • (2009) Int. Immunopharmacol , vol.9 , pp. 701-715
    • Hyde, C.A.1    Missailidis, S.2
  • 34
    • 0027304229 scopus 로고
    • Arachidonic acid in cell signaling
    • Piomelli, D. Arachidonic acid in cell signaling. Curr. Opin. Cell Biol. 1993, 5, 274-280
    • (1993) Curr. Opin. Cell Biol , vol.5 , pp. 274-280
    • Piomelli, D.1
  • 35
    • 83855165727 scopus 로고    scopus 로고
    • Cyclooxygenases and lipoxygenases in cancer
    • Schneider, C.; Pozzi, A. Cyclooxygenases and lipoxygenases in cancer. Cancer Metastasis Rev. 2011, 30, 277-294
    • (2011) Cancer Metastasis Rev , vol.30 , pp. 277-294
    • Schneider, C.1    Pozzi, A.2
  • 38
    • 0035947586 scopus 로고    scopus 로고
    • Prostaglandin E2 increases growth and motility of colorectal carcinoma cells
    • Sheng, H.; Shao, J.; Washington, M.K.; DuBois, R.N. Prostaglandin E2 increases growth and motility of colorectal carcinoma cells. J. Biol. Chem. 2001, 276, 18075-18081
    • (2001) J. Biol. Chem , vol.276 , pp. 18075-18081
    • Sheng, H.1    Shao, J.2    Washington, M.K.3    Dubois, R.N.4
  • 39
    • 0032573175 scopus 로고    scopus 로고
    • Inhibition of arachidonate 5-lipoxygenase triggers massive apoptosis in human prostate cancer cells
    • Ghosh, J.; Myers, C.E. Inhibition of arachidonate 5-lipoxygenase triggers massive apoptosis in human prostate cancer cells. Proc. Natl. Acad. Sci. USA 1998, 95, 13182-13187
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 13182-13187
    • Ghosh, J.1    Myers, C.E.2
  • 41
    • 0034662627 scopus 로고    scopus 로고
    • Inhibitors of prostaglandin synthesis inhibit human prostate tumor cell invasiveness and reduce the release of matrix metalloproteinases
    • Attiga, F.A.; Fernandez, P.M.; Weeraratna, A.T.; Manyak, M.J.; Patierno, S.R. Inhibitors of prostaglandin synthesis inhibit human prostate tumor cell invasiveness and reduce the release of matrix metalloproteinases. Cancer Res. 2000, 60, 4629-4637
    • (2000) Cancer Res , vol.60 , pp. 4629-4637
    • Attiga, F.A.1    Fernandez, P.M.2    Weeraratna, A.T.3    Manyak, M.J.4    Patierno, S.R.5
  • 42
    • 0036516460 scopus 로고    scopus 로고
    • Matrix metalloproteinases: A tail of a frog that became a prince
    • Brinckerhoff, C.E.; Matrisian, L.M. Matrix metalloproteinases: A tail of a frog that became a prince. Nat. Rev. Mol. Cell Biol. 2002, 3, 207-214
    • (2002) Nat. Rev. Mol. Cell Biol , vol.3 , pp. 207-214
    • Brinckerhoff, C.E.1    Matrisian, L.M.2
  • 43
    • 77950931419 scopus 로고    scopus 로고
    • Matrix metalloproteinases: Regulators of the tumor microenvironment
    • Kessenbrock, K.; Plaks, V.; Werb, Z. Matrix metalloproteinases: Regulators of the tumor microenvironment. Cell 2010, 141, 52-67
    • (2010) Cell , vol.141 , pp. 52-67
    • Kessenbrock, K.1    Plaks, V.2    Werb, Z.3
  • 44
    • 33847195428 scopus 로고    scopus 로고
    • Matrix metalloproteinases and the regulation of tissue remodelling
    • Page-McCaw, A.; Ewald, A.J.; Werb, Z. Matrix metalloproteinases and the regulation of tissue remodelling. Nat. Rev. Mol. Cell Biol. 2007, 8, 221-233
    • (2007) Nat. Rev. Mol. Cell Biol , vol.8 , pp. 221-233
    • Page-McCaw, A.1    Ewald, A.J.2    Werb, Z.3
  • 45
    • 0035188727 scopus 로고    scopus 로고
    • How matrix metalloproteinases regulate cell behavior
    • Sternlicht, M.D.; Werb, Z. How matrix metalloproteinases regulate cell behavior. Annu. Rev. Cell Dev. Biol. 2001, 17, 463-516
    • (2001) Annu. Rev. Cell Dev. Biol , vol.17 , pp. 463-516
    • Sternlicht, M.D.1    Werb, Z.2
  • 46
    • 54749146365 scopus 로고    scopus 로고
    • Tube travel: The role of proteases in individual and collective cancer cell invasion
    • Friedl, P.; Wolf, K. Tube travel: The role of proteases in individual and collective cancer cell invasion. Cancer Res. 2008, 68, 7247-7249
    • (2008) Cancer Res , vol.68 , pp. 7247-7249
    • Friedl, P.1    Wolf, K.2
  • 47
    • 0036716282 scopus 로고    scopus 로고
    • Strategies for MMP inhibition in cancer: Innovations for the post-trial era
    • Overall, C.M.; Lopez-Otin, C. Strategies for MMP inhibition in cancer: Innovations for the post-trial era. Nat. Rev. Cancer 2002, 2, 657-672
    • (2002) Nat. Rev. Cancer , vol.2 , pp. 657-672
    • Overall, C.M.1    Lopez-Otin, C.2
  • 48
    • 0033999308 scopus 로고    scopus 로고
    • Matrix metalloproteinases: Biologic activity and clinical implications
    • Nelson, A.R.; Fingleton, B.; Rothenberg, M.L.; Matrisian, L.M. Matrix metalloproteinases: Biologic activity and clinical implications. J. Clin. Oncol. 2000, 18, 1135-1149
    • (2000) J. Clin. Oncol , vol.18 , pp. 1135-1149
    • Nelson, A.R.1    Fingleton, B.2    Rothenberg, M.L.3    Matrisian, L.M.4
  • 50
    • 84881481410 scopus 로고    scopus 로고
    • Matrix metalloproteinases in cancer: Their value as diagnostic and prognostic markers and therapeutic targets
    • Hadler-Olsen, E.; Winberg, J.O.; Uhlin-Hansen, L. Matrix metalloproteinases in cancer: Their value as diagnostic and prognostic markers and therapeutic targets. Tumor Biol. 2013, 34, 2041-2051
    • (2013) Tumor Biol , vol.34 , pp. 2041-2051
    • Hadler-Olsen, E.1    Winberg, J.O.2    Uhlin-Hansen, L.3
  • 51
    • 66149142794 scopus 로고    scopus 로고
    • Protective effect of pomegranate-derived products on UVB-mediated damage in human reconstituted skin
    • Afaq, F.; Zaid, M.A.; Khan, N.; Dreher, M.; Mukhtar, H. Protective effect of pomegranate-derived products on UVB-mediated damage in human reconstituted skin. Exp. Dermatol. 2009, 18, 553-561
    • (2009) Exp. Dermatol , vol.18 , pp. 553-561
    • Afaq, F.1    Zaid, M.A.2    Khan, N.3    Dreher, M.4    Mukhtar, H.5
  • 52
    • 24744432725 scopus 로고    scopus 로고
    • Punica granatum l. Extract inhibits IL-1β-induced expression of matrix metalloproteinases by inhibiting the activation of map kinases and NF-κB in human chondrocytes in vitro
    • Ahmed, S.; Wang, N.; Hafeez, B.B.; Cheruvu, V.K.; Haqqi, T.M. Punica granatum l. Extract inhibits IL-1β-induced expression of matrix metalloproteinases by inhibiting the activation of map kinases and NF-κB in human chondrocytes in vitro. J. Nutr. 2005, 135, 2096-2102
    • (2005) J. Nutr , vol.135 , pp. 2096-2102
    • Ahmed, S.1    Wang, N.2    Hafeez, B.B.3    Cheruvu, V.K.4    Haqqi, T.M.5
  • 54
    • 0036440762 scopus 로고    scopus 로고
    • Strong stromal hyaluronan expression is associated with PSA recurrence in local prostate cancer
    • Aaltomaa, S.; Lipponen, P.; Tammi, R.; Tammi, M.; Viitanen, J.; Kankkunen, J.P.; Kosma, V.M. Strong stromal hyaluronan expression is associated with PSA recurrence in local prostate cancer. Urol. Int. 2002, 69, 266-272
    • (2002) Urol. Int , vol.69 , pp. 266-272
    • Aaltomaa, S.1    Lipponen, P.2    Tammi, R.3    Tammi, M.4    Viitanen, J.5    Kankkunen, J.P.6    Kosma, V.M.7
  • 55
    • 0035045589 scopus 로고    scopus 로고
    • High stromal hyaluronan level is associated with poor differentiation and metastasis in prostate cancer
    • Lipponen, P.; Aaltomaa, S.; Tammi, R.; Tammi, M.; Agren, U.; Kosma, V.M. High stromal hyaluronan level is associated with poor differentiation and metastasis in prostate cancer. Eur. J. Cancer 2001, 37, 849-856
    • (2001) Eur. J. Cancer , vol.37 , pp. 849-856
    • Lipponen, P.1    Aaltomaa, S.2    Tammi, R.3    Tammi, M.4    Agren, U.5    Kosma, V.M.6
  • 56
    • 0026559653 scopus 로고
    • Hyaluronan and cell locomotion
    • Turley, E.A. Hyaluronan and cell locomotion. Cancer Metastasis Rev. 1992, 11, 21-30
    • (1992) Cancer Metastasis Rev , vol.11 , pp. 21-30
    • Turley, E.A.1
  • 57
    • 22144434672 scopus 로고    scopus 로고
    • Hyaluronan: A critical component of epithelial-mesenchymal and epithelial-carcinoma transitions
    • Toole, B.P.; Zoltan-Jones, A.; Misra, S.; Ghatak, S. Hyaluronan: A critical component of epithelial-mesenchymal and epithelial-carcinoma transitions. Cells Tissues Organs 2005, 179, 66-72
    • (2005) Cells Tissues Organs , vol.179 , pp. 66-72
    • Toole, B.P.1    Zoltan-Jones, A.2    Misra, S.3    Ghatak, S.4
  • 58
  • 60
    • 40549131045 scopus 로고    scopus 로고
    • Androgen receptor regulates CD168 expression and signaling in prostate cancer
    • Lin, S.-L.; Chang, D.; Chiang, A.; Ying, S.-Y. Androgen receptor regulates CD168 expression and signaling in prostate cancer. Carcinogenesis 2008, 29, 282-290
    • (2008) Carcinogenesis , vol.29 , pp. 282-290
    • Lin, S.-L.1    Chang, D.2    Chiang, A.3    Ying, S.-Y.4
  • 61
    • 33847333362 scopus 로고    scopus 로고
    • Hyaluronan stimulates transformation of androgen-independent prostate cancer
    • Lin, S.-L.; Chang, D.; Ying, S.-Y. Hyaluronan stimulates transformation of androgen-independent prostate cancer. Carcinogenesis 2007, 28, 310-320
    • (2007) Carcinogenesis , vol.28 , pp. 310-320
    • Lin, S.-L.1    Chang, D.2    Ying, S.-Y.3
  • 62
    • 84867567728 scopus 로고    scopus 로고
    • Specific pomegranate juice components as potential inhibitors of prostate cancer metastasis
    • Wang, L.; Ho, J.; Glackin, C.; Martins-Green, M. Specific pomegranate juice components as potential inhibitors of prostate cancer metastasis. Transl. Oncol. 2012, 5, 344-355
    • (2012) Transl. Oncol , vol.5 , pp. 344-355
    • Wang, L.1    Ho, J.2    Glackin, C.3    Martins-Green, M.4
  • 63
    • 0242417086 scopus 로고    scopus 로고
    • Bone histology at autopsy and matched bone scintigraphy findings in patients with hormone refractory prostate cancer: The effect of bisphosphonate therapy on bone scintigraphy results
    • Roudier, M.P.; Vesselle, H.; True, L.D.; Higano, C.S.; Ott, S.M.; King, S.H.; Vessella, R.L. Bone histology at autopsy and matched bone scintigraphy findings in patients with hormone refractory prostate cancer: The effect of bisphosphonate therapy on bone scintigraphy results. Clin. Exp. Metastasis 2003, 20, 171-180
    • (2003) Clin. Exp. Metastasis , vol.20 , pp. 171-180
    • Roudier, M.P.1    Vesselle, H.2    True, L.D.3    Higano, C.S.4    Ott, S.M.5    King, S.H.6    Vessella, R.L.7
  • 64
    • 27144441519 scopus 로고    scopus 로고
    • A paradigm for the treatment of prostate cancer bone metastases based on an understanding of tumor cell-microenvironment interactions
    • Loberg, R.D.; Gayed, B.A.; Olson, K.B.; Pienta, K.J. A paradigm for the treatment of prostate cancer bone metastases based on an understanding of tumor cell-microenvironment interactions. J. Cell. Biochem. 2005, 96, 439-446
    • (2005) J. Cell. Biochem , vol.96 , pp. 439-446
    • Loberg, R.D.1    Gayed, B.A.2    Olson, K.B.3    Pienta, K.J.4
  • 67
    • 77950882020 scopus 로고    scopus 로고
    • The CXCR4/SDF-1 chemokine axis: A potential therapeutic target for bone metastases?
    • Hirbe, A.C.; Morgan, E.A.; Weilbaecher, K.N. The CXCR4/SDF-1 chemokine axis: A potential therapeutic target for bone metastases? Curr. Pharm. Des. 2010, 16, 1284-1290
    • (2010) Curr. Pharm. Des , vol.16 , pp. 1284-1290
    • Hirbe, A.C.1    Morgan, E.A.2    Weilbaecher, K.N.3
  • 68
    • 33846058844 scopus 로고    scopus 로고
    • The pivotal role of CXCL12 (SDF-1)/CXCR4 axis in bone metastasis
    • Wang, J.; Loberg, R.; Taichman, R.S. The pivotal role of CXCL12 (SDF-1)/CXCR4 axis in bone metastasis. Cancer Metastasis Rev. 2006, 25, 573-587
    • (2006) Cancer Metastasis Rev , vol.25 , pp. 573-587
    • Wang, J.1    Loberg, R.2    Taichman, R.S.3
  • 69
    • 0037085938 scopus 로고    scopus 로고
    • Use of the stromal cell-derived factor-1/CXCR4 pathway in prostate cancer metastasis to bone
    • Taichman, R.S.; Cooper, C.; Keller, E.T.; Pienta, K.J.; Taichman, N.S.; McCauley, L.K. Use of the stromal cell-derived factor-1/CXCR4 pathway in prostate cancer metastasis to bone. Cancer Res. 2002, 62, 1832-1837
    • (2002) Cancer Res , vol.62 , pp. 1832-1837
    • Taichman, R.S.1    Cooper, C.2    Keller, E.T.3    Pienta, K.J.4    Taichman, N.S.5    McCauley, L.K.6
  • 70
    • 23944441266 scopus 로고    scopus 로고
    • Interieukin-6 regulation of prostate cancer cell growth
    • Culig, Z.; Steiner, H.; Bartsch, G.; Hobisch, A. Interieukin-6 regulation of prostate cancer cell growth. J. Cell. Biochem. 2005, 95, 497-505
    • (2005) J. Cell. Biochem , vol.95 , pp. 497-505
    • Culig, Z.1    Steiner, H.2    Bartsch, G.3    Hobisch, A.4
  • 71
    • 33845606612 scopus 로고    scopus 로고
    • IL-12p40: An inherently agonistic cytokine
    • Cooper, A.M.; Khader, S.A. IL-12p40: An inherently agonistic cytokine. Trends Immunol. 2007, 28, 33-38
    • (2007) Trends Immunol , vol.28 , pp. 33-38
    • Cooper, A.M.1    Khader, S.A.2
  • 73
    • 31944433180 scopus 로고    scopus 로고
    • Expression of CCL5 (rantes) and CCR5 in prostate cancer
    • Vaday, G.G.; Peehl, D.M.; Kadam, P.A.; Lawrence, D.M. Expression of CCL5 (rantes) and CCR5 in prostate cancer. Prostate 2006, 66, 124-134
    • (2006) Prostate , vol.66 , pp. 124-134
    • Vaday, G.G.1    Peehl, D.M.2    Kadam, P.A.3    Lawrence, D.M.4
  • 74
    • 0002441238 scopus 로고    scopus 로고
    • Evolution of juice anthocyanins during ripening of new selected pomegranate (punica granatum) clones
    • Hernandez, F.; Melgarejo, P.; Tomas-Barberan, F.A.; Artes, F. Evolution of juice anthocyanins during ripening of new selected pomegranate (punica granatum) clones. Eur. Food Res. Technol. 1999, 210, 39-42
    • (1999) Eur. Food Res. Technol , vol.210 , pp. 39-42
    • Hernandez, F.1    Melgarejo, P.2    Tomas-Barberan, F.A.3    Artes, F.4
  • 75
    • 0742324892 scopus 로고    scopus 로고
    • Rapid dereplication of estrogenic compounds in pomegranate (Punica granatum) using on-line biochemical detection coupled to mass spectrometry
    • Van Elswijk, D.A.; Schobel, U.P.; Lansky, E.P.; Irth, H.; van der Greef, J. Rapid dereplication of estrogenic compounds in pomegranate (Punica granatum) using on-line biochemical detection coupled to mass spectrometry. Phytochemistry 2004, 65, 233-241
    • (2004) Phytochemistry , vol.65 , pp. 233-241
    • van Elswijk, D.A.1    Schobel, U.P.2    Lansky, E.P.3    Irth, H.4    van der Greef, J.5
  • 77
    • 16244422650 scopus 로고    scopus 로고
    • Synergistic antiproliferative action of the flavonols quercetin and kaempferol in cultured human cancer cell lines
    • Ackland, M.L.; van de Waarsenburg, S.; Jones, R. Synergistic antiproliferative action of the flavonols quercetin and kaempferol in cultured human cancer cell lines. In Vivo 2005, 19, 69-76
    • (2005) In Vivo , vol.19 , pp. 69-76
    • Ackland, M.L.1    van de Waarsenburg, S.2    Jones, R.3
  • 78
    • 84856223485 scopus 로고    scopus 로고
    • Quantitative determination of major polyphenol constituents in pomegranate products
    • Qu, W.; Breksa, A.P., III; Pan, Z.; Ma, H. Quantitative determination of major polyphenol constituents in pomegranate products. Food Chem. 2012, 132, 1585-1591
    • (2012) Food Chem , vol.132 , pp. 1585-1591
    • Qu, W.1    Breksa III., A.P.2    Pan, Z.3    Ma, H.4
  • 79
    • 0032976772 scopus 로고    scopus 로고
    • Antioxidant and eicosanoid enzyme inhibition properties of pomegranate seed oil and fermented juice flavonoids
    • Schubert, S.Y.; Lansky, E.P.; Neeman, I. Antioxidant and eicosanoid enzyme inhibition properties of pomegranate seed oil and fermented juice flavonoids. J. Ethnopharmacol. 1999, 66, 11-17
    • (1999) J. Ethnopharmacol , vol.66 , pp. 11-17
    • Schubert, S.Y.1    Lansky, E.P.2    Neeman, I.3
  • 80
    • 75449090447 scopus 로고    scopus 로고
    • Punicic acid is an OMEGA-5 fatty acid capable of inhibiting breast cancer proliferation
    • Grossmann, M.E.; Mizuno, N.K.; Schuster, T.; Cleary, M.P. Punicic acid is an OMEGA-5 fatty acid capable of inhibiting breast cancer proliferation. Int. J. Oncol. 2010, 36, 421-426
    • (2010) Int. J. Oncol , vol.36 , pp. 421-426
    • Grossmann, M.E.1    Mizuno, N.K.2    Schuster, T.3    Cleary, M.P.4
  • 81
    • 78649663492 scopus 로고    scopus 로고
    • Growth inhibitory, antiandrogenic, and pro-apoptotic effects of punicic acid in lncap human prostate cancer cells
    • Gasmi, J.; Sanderson, J.T. Growth inhibitory, antiandrogenic, and pro-apoptotic effects of punicic acid in lncap human prostate cancer cells. J. Agric. Food Chem. 2010, 58, 12149-12156
    • (2010) J. Agric. Food Chem , vol.58 , pp. 12149-12156
    • Gasmi, J.1    Sanderson, J.T.2
  • 82
    • 33749494522 scopus 로고    scopus 로고
    • Pomegranate juice ellagitannin metabolites are present in human plasma and some persist in urine for up to 48 hours
    • Seeram, N.P.; Henning, S.M.; Zhang, Y.; Suchard, M.; Li, Z.; Heber, D. Pomegranate juice ellagitannin metabolites are present in human plasma and some persist in urine for up to 48 hours. J. Nutr. 2006, 136, 2481-2485
    • (2006) J. Nutr , vol.136 , pp. 2481-2485
    • Seeram, N.P.1    Henning, S.M.2    Zhang, Y.3    Suchard, M.4    Li, Z.5    Heber, D.6
  • 83
    • 51349096457 scopus 로고    scopus 로고
    • Multitargeted therapy of cancer by ellagitannins
    • Heber, D. Multitargeted therapy of cancer by ellagitannins. Cancer Lett. 2008, 269, 262-268
    • (2008) Cancer Lett , vol.269 , pp. 262-268
    • Heber, D.1
  • 87
    • 0032923360 scopus 로고    scopus 로고
    • P53/p21 (WAF1/CIP1) expression and its possible role in G1 arrest and apoptosis in ellagic acid treated cancer cells
    • Narayanan, B.A.; Geoffroy, O.; Willingham, M.C.; Re, G.G.; Nixon, D.W. P53/p21 (WAF1/CIP1) expression and its possible role in G1 arrest and apoptosis in ellagic acid treated cancer cells. Cancer Lett. 1999, 136, 215-221
    • (1999) Cancer Lett , vol.136 , pp. 215-221
    • Narayanan, B.A.1    Geoffroy, O.2    Willingham, M.C.3    Re, G.G.4    Nixon, D.W.5
  • 89
    • 84877932636 scopus 로고    scopus 로고
    • Pomegranate juice metabolites, ellagic acid and urolithin a, synergistically inhibit androgen-independent prostate cancer cell growth via distinct effects on cell cycle control and apoptosis
    • Vicinanza, R.; Zhang, Y.; Henning, S.M.; Heber, D. Pomegranate juice metabolites, ellagic acid and urolithin a, synergistically inhibit androgen-independent prostate cancer cell growth via distinct effects on cell cycle control and apoptosis. Evid.-Based Complement. Alternat. Med. 2013, 2013, 247-504
    • (2013) Evid.-Based Complement. Alternat. Med , vol.2013 , pp. 247-504
    • Vicinanza, R.1    Zhang, Y.2    Henning, S.M.3    Heber, D.4
  • 90
    • 0032756794 scopus 로고    scopus 로고
    • Effects of luteolin and quercetin, inhibitors of tyrosine kinase, on cell growth and metastasis-associated properties in a431 cells overexpressing epidermal growth factor receptor
    • Huang, Y.T.; Hwang, J.J.; Lee, P.P.; Ke, F.C.; Huang, J.H.; Huang, C.J.; Kandaswami, C.; Middleton, E., Jr.; Lee, M.T. Effects of luteolin and quercetin, inhibitors of tyrosine kinase, on cell growth and metastasis-associated properties in a431 cells overexpressing epidermal growth factor receptor. Br. J. Pharmacol. 1999, 128, 999-1010
    • (1999) Br. J. Pharmacol , vol.128 , pp. 999-1010
    • Huang, Y.T.1    Hwang, J.J.2    Lee, P.P.3    Ke, F.C.4    Huang, J.H.5    Huang, C.J.6    Kandaswami, C.7    Middleton Jr., E.8    Lee, M.T.9
  • 91
    • 33646411225 scopus 로고    scopus 로고
    • Luteolin promotes degradation in signal transducer and activator of transcription 3 in human hepatoma cells: An implication for the antitumor potential of flavonoids
    • Selvendiran, K.; Koga, H.; Ueno, T.; Yoshida, T.; Maeyama, M.; Torimura, T.; Yano, H.; Kojiro, M.; Sata, M. Luteolin promotes degradation in signal transducer and activator of transcription 3 in human hepatoma cells: An implication for the antitumor potential of flavonoids. Cancer Res. 2006, 66, 4826-4834
    • (2006) Cancer Res , vol.66 , pp. 4826-4834
    • Selvendiran, K.1    Koga, H.2    Ueno, T.3    Yoshida, T.4    Maeyama, M.5    Torimura, T.6    Yano, H.7    Kojiro, M.8    Sata, M.9
  • 92
    • 33846179993 scopus 로고    scopus 로고
    • Induction of cell cycle arrest and apoptosis in HT-29 human colon cancer cells by the dietary compound luteolin
    • Lim, Y.; Jeong, Y.; Tyner, A.L.; Park, J.H. Induction of cell cycle arrest and apoptosis in HT-29 human colon cancer cells by the dietary compound luteolin. Am. J. Physiol. Gastrointest. Liver Physiol. 2007, 292, G66-G75
    • (2007) Am. J. Physiol. Gastrointest. Liver Physiol , vol.292
    • Lim, Y.1    Jeong, Y.2    Tyner, A.L.3    Park, J.H.4
  • 93
    • 67649383604 scopus 로고    scopus 로고
    • Luteolin inhibits invasion of prostate cancer pc3 cells through E-cadherin
    • Zhou, Q.; Yan, B.; Hu, X.; Li, X.B.; Zhang, J.; Fang, J. Luteolin inhibits invasion of prostate cancer pc3 cells through E-cadherin. Mol. Cancer Ther. 2009, 8, 1684-1691
    • (2009) Mol. Cancer Ther , vol.8 , pp. 1684-1691
    • Zhou, Q.1    Yan, B.2    Hu, X.3    Li, X.B.4    Zhang, J.5    Fang, J.6
  • 94
    • 0037459077 scopus 로고    scopus 로고
    • Sticky business: Orchestrating cellular signals at adherens junctions
    • Perez-Moreno, M.; Jamora, C.; Fuchs, E. Sticky business: Orchestrating cellular signals at adherens junctions. Cell 2003, 112, 535-548
    • (2003) Cell , vol.112 , pp. 535-548
    • Perez-Moreno, M.1    Jamora, C.2    Fuchs, E.3
  • 95
    • 77953879928 scopus 로고    scopus 로고
    • Involvement of members of the cadherin superfamily in cancer
    • Berx, G.; van Roy, F. Involvement of members of the cadherin superfamily in cancer. Cold Spring Harb. Perspect. Biol. 2009, 1, a003129
    • (2009) Cold Spring Harb. Perspect. Biol , vol.1
    • Berx, G.1    van Roy, F.2
  • 96
    • 0036595629 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transitions in tumour progression
    • Thiery, J.P. Epithelial-mesenchymal transitions in tumour progression. Nat. Rev. Cancer 2002, 2, 442-454
    • (2002) Nat. Rev. Cancer , vol.2 , pp. 442-454
    • Thiery, J.P.1
  • 97
    • 84871729357 scopus 로고    scopus 로고
    • Luteolin inhibits human prostate tumor growth by suppressing vascular endothelial growth factor receptor 2-mediated angiogenesis
    • Pratheeshkumar, P.; Son, Y.O.; Budhraja, A.; Wang, X.; Ding, S.; Wang, L.; Hitron, A.; Lee, J.C.; Kim, D.; Divya, S.P., et al. Luteolin inhibits human prostate tumor growth by suppressing vascular endothelial growth factor receptor 2-mediated angiogenesis. PLoS One 2012, 7, e52279
    • (2012) PLoS One , vol.7
    • Pratheeshkumar, P.1    Son, Y.O.2    Budhraja, A.3    Wang, X.4    Ding, S.5    Wang, L.6    Hitron, A.7    Lee, J.C.8    Kim, D.9    Divya, S.P.10
  • 98
    • 84876585707 scopus 로고    scopus 로고
    • Pomegranate juice and specific components inhibit cell and molecular processes critical for metastasis of breast cancer
    • Rocha, A.; Wang, L.; Penichet, M.; Martins-Green, M. Pomegranate juice and specific components inhibit cell and molecular processes critical for metastasis of breast cancer. Breast Cancer Res. Treat. 2012, 136, 647-658
    • (2012) Breast Cancer Res. Treat , vol.136 , pp. 647-658
    • Rocha, A.1    Wang, L.2    Penichet, M.3    Martins-Green, M.4
  • 99
    • 84859416889 scopus 로고    scopus 로고
    • Pten loss and RAS/MAPK activation cooperate to promote emt and metastasis initiated from prostate cancer stem/progenitor cells
    • Mulholland, D.J.; Kobayashi, N.; Ruscetti, M.; Zhi, A.; Tran, L.M.; Huang, J.; Gleave, M.; Wu, H. Pten loss and RAS/MAPK activation cooperate to promote emt and metastasis initiated from prostate cancer stem/progenitor cells. Cancer Res. 2012, 72, 1878-1889
    • (2012) Cancer Res , vol.72 , pp. 1878-1889
    • Mulholland, D.J.1    Kobayashi, N.2    Ruscetti, M.3    Zhi, A.4    Tran, L.M.5    Huang, J.6    Gleave, M.7    Wu, H.8
  • 100
    • 84906839766 scopus 로고    scopus 로고
    • Luteolin, ellagic acid and punicic acid are natural products that inhibit prostate cancer metastasis
    • doi:10.1093/carcin/bgu145
    • Wang, L.; Garcia, M.; Mulholland, D.; Lily, M.; Martins-Green, M. Luteolin, ellagic acid and punicic acid are natural products that inhibit prostate cancer metastasis. Carcinogenesis 2014, doi:10.1093/carcin/bgu145
    • (2014) Carcinogenesis
    • Wang, L.1    Garcia, M.2    Mulholland, D.3    Lily, M.4    Martins-Green, M.5
  • 103
    • 84887986296 scopus 로고    scopus 로고
    • A double-blind, randomized, neoadjuvant study of the tissue effects of pomx pills in men with prostate cancer prior to radical prostatectomy
    • Freedland, S.J.; Carducci, M.A.; Kroeger, N.; Partin, A.W.; Rao, J.; Jin, Y.; Kerkoutian, S.; Wu, H.; Li, Y.; Creel, P., et al. A double-blind, randomized, neoadjuvant study of the tissue effects of pomx pills in men with prostate cancer prior to radical prostatectomy. Cancer Prev. Res. 2013, 10, 1120-1127
    • (2013) Cancer Prev. Res , vol.10 , pp. 1120-1127
    • Freedland, S.J.1    Carducci, M.A.2    Kroeger, N.3    Partin, A.W.4    Rao, J.5    Jin, Y.6    Kerkoutian, S.7    Wu, H.8    Li, Y.9    Creel, P.10
  • 104
    • 84901197775 scopus 로고    scopus 로고
    • A double-blind, placebo-controlled randomised trial evaluating the effect of a polyphenol-rich whole food supplement on PSA progression in men with prostate cancer-The U.K. NCRN POMI-T study
    • Thomas, R.; Williams, M.; Sharma, H.; Chaudry, A.; Bellamy, P. A double-blind, placebo-controlled randomised trial evaluating the effect of a polyphenol-rich whole food supplement on PSA progression in men with prostate cancer-The U.K. NCRN POMI-T study. Prostate Cancer Prostatic Dis. 2014, 17, 180-186
    • (2014) Prostate Cancer Prostatic Dis , vol.17 , pp. 180-186
    • Thomas, R.1    Williams, M.2    Sharma, H.3    Chaudry, A.4    Bellamy, P.5
  • 105
    • 77952537236 scopus 로고    scopus 로고
    • Cancer chemoprevention by pomegranate: Laboratory and clinical evidence
    • Adhami, V.M.; Khan, N.; Mukhtar, H. Cancer chemoprevention by pomegranate: Laboratory and clinical evidence. Nutr. Cancer 2009, 61, 811-815.
    • (2009) Nutr. Cancer , vol.61 , pp. 811-815
    • Adhami, V.M.1    Khan, N.2    Mukhtar, H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.