Comparative pharmacokinetics of rhein in normal and loperamide-induced constipated rats and microarray analysis of drug-metabolizing genes

Journal of Ethnopharmacology

Volumn 155, Issue 2, 2014, Pages 1291-1299

  Hou, Mei Ling ^a   Chang, Li Wen ^a   Lin, Chi Hung ^a   Lin, Lie Chwen ^b   Tsai, Tung Hu ^a,c,d  

^a NATIONAL YANG MING UNIVERSITY   (Taiwan)

^b NATIONAL RESEARCH INSTITUTE OF CHINESE MEDICINE   (Taiwan)

^c CHINA MEDICAL UNIVERSITY   (Taiwan)

^d TAIPEI CITY HOSPITAL   (Taiwan)

Author keywords

Loperamide induced constipation; Microarray; Pharmacokinetics; Rhein; Traditional Chinese medicine

Indexed keywords

CHOLESTEROL 7ALPHA MONOOXYGENASE; CYTOCHROME P450 2C; CYTOCHROME P450 2C6; DRUG METABOLIZING ENZYME; IBUPROFEN; LOPERAMIDE; PLANT MEDICINAL PRODUCT; RHEIN; SAN HUANG XIE XIN TANG; SOLUTE CARRIER ORGANIC ANION TRANSPORTER 1B1; UNCLASSIFIED DRUG; ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); AMINO ACID TRANSPORTER; ANTHRAQUINONE DERIVATIVE; ATP1B1 PROTEIN, RAT; CARBOXYLESTERASE; CYP2C6 PROTEIN, RAT; CYP7A1 PROTEIN, RAT; LAXATIVE; SLC7A2 PROTEIN, RAT; STEROID 21 MONOOXYGENASE;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AREA UNDER THE CURVE; ARTICLE; CONSTIPATION; CONTROLLED STUDY; DRUG ABSORPTION; DRUG HALF LIFE; ELECTROSPRAY MASS SPECTROMETRY; ELIMINATION HALF-LIFE; GENE EXPRESSION PROFILING; HERB; LIMIT OF DETECTION; MALE; MAXIMUM PLASMA CONCENTRATION; MEAN RESIDENCE TIME; MICROARRAY ANALYSIS; NONHUMAN; NUCLEOTIDE SEQUENCE; PLASMA CONCENTRATION-TIME CURVE; RAT; REAL TIME POLYMERASE CHAIN REACTION; TANDEM MASS SPECTROMETRY; TIME TO MAXIMUM PLASMA CONCENTRATION; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY; VOLUME OF DISTRIBUTION; ANIMAL; BIOTRANSFORMATION; CHEMICALLY INDUCED; COMPARATIVE STUDY; DISEASE MODEL; DNA MICROARRAY; ENZYMOLOGY; GENE EXPRESSION REGULATION; GENETICS; HALF LIFE TIME; LIQUID CHROMATOGRAPHY; MEDICINAL PLANT; METABOLIC CLEARANCE RATE; METABOLISM; PHARMACOGENETICS; PHYTOTHERAPY; PROCEDURES; REPRODUCIBILITY; SPRAGUE DAWLEY RAT;

RATTUS; RHEUM PALMATUM;

AMINO ACID TRANSPORT SYSTEMS, BASIC; ANIMALS; ANTHRAQUINONES; AREA UNDER CURVE; BIOTRANSFORMATION; CARBOXYLIC ESTER HYDROLASES; CHOLESTEROL 7-ALPHA-HYDROXYLASE; CHROMATOGRAPHY, LIQUID; CONSTIPATION; DISEASE MODELS, ANIMAL; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HALF-LIFE; LAXATIVES; LOPERAMIDE; MALE; METABOLIC CLEARANCE RATE; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PHARMACOGENETICS; PHYTOTHERAPY; PLANTS, MEDICINAL; RATS, SPRAGUE-DAWLEY; REAL-TIME POLYMERASE CHAIN REACTION; REPRODUCIBILITY OF RESULTS; SODIUM-POTASSIUM-EXCHANGING ATPASE; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; STEROID 21-HYDROXYLASE; TANDEM MASS SPECTROMETRY;

EID: 84906794025     PISSN: 03788741     EISSN: 18727573     Source Type: Journal    
DOI: 10.1016/j.jep.2014.07.022     Document Type: Article

References (38)

1. M. Camilleri Opioid-induced constipation: challenges and therapeutic opportunities The American Journal of Gastroenterology 106 2011 835 842 (quiz 843)
2. M. Camilleri, and A.E. Bharucha Behavioural and new pharmacological treatments for constipation: getting the balance right Gut 59 2010 1288 1296
3. B. Candy, L. Jones, M.L. Goodman, R. Drake, and A. Tookman Laxatives or methylnaltrexone for the management of constipation in palliative care patients Cochrane Database of Systematic Reviews (Online) 1 2011 CD003448
4. H.M. Cheng, C.C. Li, C.Y. Chen, H.Y. Lo, W.Y. Cheng, C.H. Lee, S.Z. Yang, S.L. Wu, C.Y. Hsiang, and T.Y. Ho Application of bioactivity database of Chinese herbal medicine on the therapeutic prediction, drug development, and safety evaluation Journal of Ethnopharmacology 132 2010 429 437
5. W.Y. Cheng, S.L. Wu, C.Y. Hsiang, C.C. Li, T.Y. Lai, H.Y. Lo, W.S. Shen, C.H. Lee, J.C. Chen, H.C. Wu, and T.Y. Ho Relationship between San-Huang-Xie-Xin-Tang and its herbal components on the gene expression profiles in HepG2 cells The American Journal of Chinese Medicine 36 2008 783 797
6. W.D. Chey, M. Maneerattaporn, and R. Saad Pharmacologic and complementary and alternative medicine therapies for irritable bowel syndrome Gut and Liver 5 2011 253 266
7. X.Y. Dai, Y.L. Yan, Q.F. Wu, C.H. Yu, X. Liu, and Y.Q. Jiang Comparative pharmacokinetics of rhein and chrysophanol after oral administration of Quyu Qingre granules in normal and acute blood stasis rabbits Journal of Ethnopharmacology 153 2014 338 343
8. S.X. Feng, J.S. Li, L.B. Qu, Y.M. Shi, and D. Zhao Comparative pharmacokinetics of five rhubarb anthraquinones in normal and thrombotic focal cerebral ischemia-induced rats Phytotherapy Research: PTR 27 2013 1489 1494
9. L. Guo, N. Mei, W. Liao, P.C. Chan, and P.P. Fu Ginkgo biloba extract induces gene expression changes in xenobiotics metabolism and the Myc-centered network OMICS: A Journal of Integrative Biology 14 2010 75 90
10. L. Guo, N. Mei, Q. Xia, T. Chen, P.C. Chan, and P.P. Fu Gene expression profiling as an initial approach for mechanistic studies of toxicity and tumorigenicity of herbal plants and herbal dietary supplements Journal of Environmental Science and Health. Part C, Environmental Carcinogenesis & Ecotoxicology Reviews 28 2010 60 87
11. L. Guo, Q. Shi, S. Dial, Q. Xia, N. Mei, Q.Z. Li, P.C. Chan, and P. Fu Gene expression profiling in male B6C3F1 mouse livers exposed to kava identifies - changes in drug metabolizing genes and potential mechanisms linked to kava toxicity Food and Chemical Toxicology: An International Journal Published for the British Industrial Biological Research Association 48 2010 686 696
12. X.H. Han, J. Zhong, J.Y. Guo, R. Shi, X.H. Wang, C.H. Wang, K. Wang, G.L. Du, Y.H. Shen, and Y.M. Ma Relationships between pharmacokinetics and efficacy of Xie-xin decoction in rats with experimental ulcerative colitis Journal of Ethnopharmacology 148 2013 182 189
13. M.L. Hou, L.W. Chang, C.H. Lin, L.C. Lin, and T.H. Tsai Determination of bioactive components in chinese herbal formulae and pharmacokinetics of rhein in rats by UPLC-MS/MS Molecules 19 2014 4058 4075
14. J.Y. Jiang, M.W. Yang, W. Qian, H. Lin, Y. Geng, Z.Q. Zhou, and D.W. Xiao Quantitative determination of rhein in human plasma by liquid chromatography-negative electrospray ionization tandem mass/mass spectrometry and the application in a pharmacokinetic study Journal of Pharmaceutical and Biomedical Analysis 57 2012 19 25
15. M.S. Jong, S.J. Hwang, Y.C. Chen, T.J. Chen, F.J. Chen, and F.P. Chen Prescriptions of Chinese herbal medicine for constipation under the national health insurance in Taiwan Journal of the Chinese Medical Association: JCMA 73 2010 375 383
16. M. Kakino, H. Izuta, T. Ito, K. Tsuruma, Y. Araki, M. Shimazawa, M. Oyama, M. Iinuma, and H. Hara Agarwood induced laxative effects via acetylcholine receptors on loperamide-induced constipation in mice Bioscience, Biotechnology, and Biochemistry 74 2010 1550 1555
17. M. Kakino, H. Izuta, K. Tsuruma, Y. Araki, M. Shimazawa, K. Ichihara, and H. Hara Laxative effects and mechanism of action of Brazilian green propolis BMC Complementary and Alternative Medicine 12 2012 192
18. J.E. Kim, Y.J. Lee, M.H. Kwak, J. Ko, J.T. Hong, and D.Y. Hwang Aqueous extracts of Liriope platyphylla induced significant laxative effects on loperamide-induced constipation of SD rats BMC Complementary and Alternative Medicine 13 2013 333
19. J.N. Lai, C.T. Wu, and J.D. Wang Prescription pattern of chinese herbal products for breast cancer in taiwan: a population-based study Evidence-based Complementary and Alternative Medicine: eCAM 2012 2012 891893
20. S. Meite, C. Bahi, D. Yeo, J.Y. Datte, J.A. Djaman, and J. N'Guessan D Laxative activities of Mareya micrantha (Benth.) Mull. Arg. (Euphorbiaceae) leaf aqueous extract in rats BMC Complementary and Alternative Medicine 10 2010 7
21. S. Muller-Lissner Pharmacokinetic and pharmacodynamic considerations for the current chronic constipation treatments Expert Opinion on Drug Metabolism & Toxicology 9 2013 391 401
22. S. Reagan-Shaw, M. Nihal, and N. Ahmad Dose translation from animal to human studies revisited FASEB Journal: Official Publication of the Federation of American Societies for Experimental Biology 22 2008 659 661
23. L.R. Schiller, C.A. Santa Ana, S.G. Morawski, and J.S. Fordtran Mechanism of the antidiarrheal effect of loperamide Gastroenterology 86 1984 1475 1480
24. L.H. Shaw, L.C. Lin, and T.H. Tsai HPLC-MS/MS analysis of a traditional Chinese medical formulation of Bu-Yang-Huan-Wu-Tang and its pharmacokinetics after oral administration to rats PloS ONE 7 2012 e43848
25. Y. Shi, C. Sun, B. Gao, and A. Sun Development of a liquid chromatography tandem mass spectrometry method for simultaneous determination of eight adulterants in slimming functional foods Journal of Chromatography. A 1218 2011 7655 7662
26. C.S. Shia, Y.C. Hou, S.H. Juang, S.Y. Tsai, P.H. Hsieh, L.C. Ho, and P.D. Chao Metabolism and pharmacokinetics of san-huang-xie-xin-tang, a polyphenol-rich chinese medicine formula, in rats and ex-vivo antioxidant activity Evidence-based Complementary and Alternative Medicine: eCAM 2011 2011 721293
27. W.T. Shih, Y.H. Yang, and P.C. Chen Prescription patterns of chinese herbal products for osteoporosis in taiwan: a population-based study Evidence-based Complementary and Alternative Medicine: eCAM 2012 2012 752837
28. A. Shimotoyodome, S. Meguro, T. Hase, I. Tokimitsu, and T. Sakata Decreased colonic mucus in rats with loperamide-induced constipation Comparative Biochemistry and Physiology. Part A, Molecular & Integrative Physiology 126 2000 203 212
29. N.R. Trivedi, M.G. Rajan, J.R. Johnson, and A.J. Shukla Pharmaceutical approaches to preparing pelletized dosage forms using the extrusion- spheronization process Critical Reviews in Therapeutic Drug Carrier Systems 24 2007 1 40
30. Z. Wen, Z. Wang, S. Wang, R. Ravula, L. Yang, J. Xu, C. Wang, Z. Zuo, M.S. Chow, L. Shi, and Y. Huang Discovery of molecular mechanisms of traditional Chinese medicinal formula Si-Wu-Tang using gene expression microarray and connectivity map PloS ONE 6 2011 e18278
31. O.A. Wintola, T.O. Sunmonu, and A.J. Afolayan The effect of Aloe ferox Mill. in the treatment of loperamide-induced constipation in Wistar rats BMC Gastroenterology 10 2010 95
32. O.A. Wintola, T.O. Sunmonu, and A.J. Afolayan Toxicological evaluation of aqueous extract of Aloe ferox Mill. in loperamide-induced constipated rats Human & Experimental Toxicology 30 2011 425 431
33. D. Wu, X. Wang, J. Zhou, J. Yuan, B. Cui, R. An, and Z. Hu Traditional Chinese formula, lubricating gut pill, improves loperamide-induced rat constipation involved in enhance of Cl- secretion across distal colonic epithelium Journal of Ethnopharmacology 130 2010 347 353
34. D. Wu, J. Zhou, X. Wang, B. Cui, R. An, H. Shi, J. Yuan, and Z. Hu Traditional Chinese formula, lubricating gut pill, stimulates cAMP-dependent CI(-) secretion across rat distal colonic mucosa Journal of Ethnopharmacology 134 2011 406 413
35. L. Yin, B. Lu, Y. Qi, L. Xu, X. Han, Y. Xu, J. Peng, and C. Sun Simultaneous determination of 11 active components in two well-known traditional Chinese medicines by HPLC coupled with diode array detection for quality control Journal of Pharmaceutical and Biomedical Analysis 49 2009 1101 1108
36. B. Zan, R. Shi, T. Wang, J. Wu, Y. Ma, and N. Cheng Simultaneous quantification of multiple active components from Xiexin decoction in rat plasma by LC-ESI-MS/MS: application in pharmacokinetics Biomedical Chromatography: BMC 25 2011 816 826
37. Q. Zhang, Y.M. Ma, Z.T. Wang, and C.H. Wang Differences in pharmacokinetics and anti-inflammatory effects between decoction and maceration of Sanhuang Xiexin Tang in rats and mice Planta Medica 79 2013 1666 1673
38. S.F. Zhu, W.W. Chen, J. Xiang, X.L. Zhao, M.H. Wan, Q. Yu, M.Z. Liang, and W.F. Tang Pharmacokinetic and pharmacodynamic comparison of chinese herbal ointment liu-he-dan and micron liu-he-dan ointment in rats with acute pancreatitis Evidence-based Complementary and Alternative Medicine: eCAM 2014 2014 389576