Laxative activities of Mareya micrantha (Benth.) Müll. Arg. (Euphorbiaceae) leaf aqueous extract in rats

BMC Complementary and Alternative Medicine

Volumn 10, Issue , 2010, Pages

  Méité, Souleymane ^a   Bahi, Calixte ^a   Yéo, Dodéhé ^a   Datté, Jacques Y ^a   Djaman, Joseph A ^a   N'guessan, David J ^a  

^a UNIVERSITÉ FÉLIX HOUPHOUËT BOIGNY   (Côte d’Ivoire)

Author keywords

[No Author keywords available]

Indexed keywords

ALKALOID; CALCIUM ION; CASTOR OIL; CHLORIDE ION; FLAVONOID; HERBACEOUS AGENT; MAREYA MICRANTHA EXTRACT; PICOSULFATE SODIUM; POLYPHENOL DERIVATIVE; POTASSIUM ION; SODIUM ION; STEROL; TANNIN DERIVATIVE; TERPENE; UNCLASSIFIED DRUG; ION; LAXATIVE; LOPERAMIDE; PLANT EXTRACT; WATER;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CALCIUM EXCRETION; CONSTIPATION; CONTROLLED STUDY; DOSE RESPONSE; DRUG ACTIVITY; DRUG SCREENING; EUPHORBIA; FECES ANALYSIS; GASTROINTESTINAL TRANSIT; INTESTINE FLUID; MAREYA MICRANTHA; NONHUMAN; PLANT LEAF; POTASSIUM EXCRETION; RAT; SODIUM EXCRETION; ANIMAL; CHEMICALLY INDUCED DISORDER; CHEMISTRY; DRUG EFFECT; GASTROINTESTINAL MOTILITY; INTESTINE; ISOLATION AND PURIFICATION; METABOLISM; PHYTOTHERAPY; WISTAR RAT;

ANIMALS; CASTOR OIL; CONSTIPATION; DOSE-RESPONSE RELATIONSHIP, DRUG; EUPHORBIACEAE; GASTROINTESTINAL MOTILITY; INTESTINES; IONS; LAXATIVES; LOPERAMIDE; PHYTOTHERAPY; PLANT EXTRACTS; PLANT LEAVES; RATS; RATS, WISTAR; WATER;

EID: 77649167660     PISSN: None     EISSN: 14726882     Source Type: Journal    
DOI: 10.1186/1472-6882-10-7     Document Type: Article

References (29)

1. Muller-Lissner S. The patholophysiology, diagnosis and treatment of constipation. Dtsch Artztebl Int 2009, 106:424-432.
2. Higgins PD, Johanson JF. Epidemiology of constipation in North America: a systematic review. Am J Gastroenterol 2004, 99:750-759. 10.1111/j.1572-0241.2004.04114.x, 15089911.
3. Bosshard W, Dreher R, SChnegg JF, Bula CJ. The treatment of chronic constipation in elderly people: an update. Drugs Aging 2004, 21:911-930. 10.2165/00002512-200421140-00002, 15554750.
4. Johanson JF, Kralstein J. Chronic constipation: a survey of the patient perspective. Aliment Pharmacol Ther 2007, 25:599-608.
5. Bengtsson M, Ohlsson B. Psychological well-being and symptoms in women with chronic constipation treated with sodium picosulphate. Gastroenterol Nurs 2005, 28:3-12. 10.1097/00001610-200501000-00002, 15738724.
6. N'guessan K. Contribution à l'étude ethnobotanique chez les Krobou de la souspréfecture d'Agboville (Côte d'Ivoire). Thèse de Doctorat 3ème cycle 1995, Université d'Abidjan-Cocody, Botanique et biologie végétale.
7. Mac Foy CA, Cline EI. In vitro antibacterial activities of three plants used in traditional medicine in Sierra Leone. J Ethnopharmacol 1990, 28:323-327. 10.1016/0378-8741(90)90083-6, 2335960.
8. Guede-guina F, Tsai CS, Smith MO, Vangah MM, Washington B, Ochillo RF. The use of isoleted functional heart to pharmacologically characterize active ingredient in the aqueous extracts of Mareya micrantha. J Ethnopharmacol 1995, 45:19-26. 10.1016/0378-8741(94)01190-B, 7739223.
9. Abo KJ-C, Aka KJ, Ehile EE, Guede Guina F, Traore F. Effets cholinergiques d'un extrait aqueux brut de Mareya micrantha (Euphorbiacée) sur la pression et d'activité cardiaque. Revue Med Pharm Afr 2000, 5:11-20.
10. Tsai CS, Guede Guina F, Smith MO, Vangah MM, Ochillo RF. Isolation of cholinergic active ingredients in aqueouse extracts of Mareya micrantha using the longitudinal muscle of isolated guinea-pig ileum as a pharmacological activity marker. J Ethnopharmacol 1995, 45:215-222. 10.1016/0378-8741(94)01219-P, 7623487.
11. Zirihi GN, Mambu L, Guédé-Guina F, Bodo B, Grellier P. In vitro antiplasmodial activity and cytotoxicity of 33 West African plants used for the treatment of malaria. J Ethnopharmacol 2005, 98:281-285. 10.1016/j.jep.2005.01.004, 15814260.
12. Silva GL, Lee I, Kinghorn AD. Special problems with the extraction of plants. Methods in Biotechnology (Natural product Isolation) 1998, 343-363. New Jersey: Humana press, Cannell RJP.
13. Mascolo N, Izzo AA, Avtore G, Barboto F, Capasso F. Nitric oxide and castor oil induced diarrhea. J Pharmacol Exp Therap 1994, 268:291-295.
14. Robert A, Nezamis JE, Lancaster C, Hanchar AJ, Klepper MS. Enteropooling assay, a test for diarrhea produced by prostaglandins. Prostaglandins 1976, 11:809-828. 10.1016/0090-6980(76)90189-1, 935512.
15. Pazhani GP, Subramanian N, Arunchalam G, Hemalatha S, Ravichandran V. Antidiarrheal potencial of Elephantopus Scaber Linn leaf extract. Ind drugs 2001, 38:269-271.
16. Capasso F, Mascolo N, Autore G, Romano V. Laxatives and the production of autacoids by rat colon. J pharm Pharmacol 1986, 38:627-629.
17. Takaharu S, Fujie M, Yuji L, Kouji M, Hideo K. Laxative and Antidiarrheal activity of polycarbophil in mice and rats. Jpn J Pharmacol 2002, 89:133-141. 10.1254/jjp.89.133, 12120755.
18. Izzo AA, Mascolo N, Viola P, Capasso F. Inhibitors of nitric oxide synthase enhance rat ileum contractions induced by ricinoleic acid in vitro. Eur J Pharmacol 1993, 243:87-90. 10.1016/0014-2999(93)90172-E, 7504631.
19. Chitme HR, Chandra R, Kaushik S. Studies on Antidiarrheal activity on calotropis gigantean in experimental animals. J Pharm Pharmaceut Sci 2004, 7:70-75.
20. Ammon HV, Thomas PJ, Phillips SF. Effect of the oleic acid and ricinoleic acid net jejunal water and electrolyte movement. J Clin Invest 1974, 53:374-379. 10.1172/JCI107569, 301478, 11344549.
21. Galvez J, Zavzuelo A, Crespo ME, Lorente MD, Ocete MA, Jimenez J. Anti-diarrhoeic activity of Euphorbia hirta extract and isolation of an active flavonoid constituent. Planta Med 1993, 59:333-336. 10.1055/s-2006-959694, 8372151.
22. Hughes S, Higgs NB, Turnberg LA. Loperamide has antisecretory activity in the human jejunum in vivo. Gut 1984, 25:931-935. 10.1136/gut.25.9.931, 1432486, 6590431.
23. Lawrence RS, Carol ASA, Stephen GM, John SF. Mechanism of the Antidiarrheal effect of loperamide. Gastroenterology 1984, 86:1475-1480.
24. Kim DH, Hyun SH, Shim SB, Kobashi K. The rôle of intestinal bacteria in the transformation of sodium picosulphate. Jpn J Pharmacol 1992, 59:1-5. 10.1254/jjp.59.1, 1507649.
25. Chatsri D, Sutthasinee P, Watchareewan T, Nateetip K. Barakol Extracted from Cassia Siamea stimulates chloride secretion in rat colon. J pharmacol Exp Ther 2005, 314:732-734. 10.1124/jpet.105.084210, 15870391.
26. Traoré F, Dosso M, Guede-Guede F, Aka KJ. Effet myostimulant d'un extrait aqueux de Mareya micrantha (Euphorbiaceae) sur l'activité contractile intestinale de lapin. Ethnopharmacologie 2004, 33:45-59.
27. Huizinga JD, Ambrous K, Der-Silaphet T. Cooperation between neural and myogenic mechanisms in the control of distension-induced peristalsis in the mouse small intestine. J Physiol 1998, 506:843-56. 10.1111/j.1469-7793.1998.843bv.x, 2230746, 9503342.
28. Waterman SA, Costa M. The role of enteric inhibitory motoneurons in peristalsis in the isolated guinea-pig small intestine. J Physiol 1994, 477:459-468. 1155610, 7932234.
29. Longanga-Otshudi A, Vercruysse A, Foriers A. Contribution to the ethnobotanical, phytochemical and pharmacological studies of traditionally used medicinal plants in the treatment of dysentery and diarrhea in Lomela area, Democratic Republic of Congo (DRC). J Ethnopharmacol 2000, 71:411-423. 10.1016/S0378-8741(00)00167-7, 10940578.