Traditional Chinese formula, lubricating gut pill, improves loperamide-induced rat constipation involved in enhance of Cl- secretion across distal colonic epithelium

Journal of Ethnopharmacology

Volumn 130, Issue 2, 2010, Pages 347-353

  Wu, Dazheng ^a,b,c   Wang, Xinhong ^a   Zhou, Jiyan ^a,b   Yuan, Jianye ^a,b   Cui, Bo ^a   An, Rui ^a   Hu, Zhibi ^a,b  

^a SHANGHAI UNIVERSITY OF TRADITIONAL CHINESE MEDICINE   (China)

^b Shanghai Key Laboratory of Complex Prescription   (China)

^c China swzlym onlineshcn   (China)

Author keywords

Cl secretion; Colonic epithelium; Constipation; Laxative effect; Lubricating gut pill

Indexed keywords

ANGELICA SINENSIS EXTRACT; ATROPINE; BUMETANIDE; CANNABIS; CHLORIDE CHANNEL; CHLORIDE ION; CLOTRIMAZOLE; CYCLIC AMP; HEXAMETHONIUM; INDOMETACIN; LOPERAMIDE; LUBRICATING AGENT; LUBRICATING GUT PILL; PLANT EXTRACT; POTASSIUM CHANNEL; PRUNUS PERSICA EXTRACT; REHMANNIA GLUTINOSA EXTRACT; TETRODOTOXIN; TRIFOLIATE ORANGE EXTRACT; UNCLASSIFIED DRUG; CHLORIDE; CHOLINERGIC RECEPTOR BLOCKING AGENT; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; HERBACEOUS AGENT; LAXATIVE; LOOP DIURETIC AGENT; POTASSIUM CHANNEL BLOCKING AGENT; PROSTAGLANDIN SYNTHASE; PROSTAGLANDIN SYNTHASE INHIBITOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CHINESE MEDICINE; COLON MUCOSA; CONCENTRATION RESPONSE; CONSTIPATION; CONTROLLED STUDY; DESCENDING COLON; INTESTINE SECRETION; ION TRANSPORT; MALE; NONHUMAN; RAT; TRIFOLIATE ORANGE; WATER CONTENT; ANIMAL; ANTAGONISTS AND INHIBITORS; CHEMICALLY INDUCED; COLON; DEFECATION; DISEASE MODEL; DOSE RESPONSE; DRUG EFFECTS; INTESTINAL SECRETIONS; INTESTINE MUCOSA; MEMBRANE POTENTIAL; METABOLISM; OSMOSIS; PATHOPHYSIOLOGY; SECRETION (PROCESS); WISTAR RAT;

ANIMALS; CHLORIDES; CHOLINERGIC ANTAGONISTS; COLON; CONSTIPATION; CYCLIC AMP; CYCLOOXYGENASE INHIBITORS; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; DEFECATION; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUGS, CHINESE HERBAL; INTESTINAL MUCOSA; INTESTINAL SECRETIONS; LAXATIVES; LOPERAMIDE; MALE; MEDICINE, CHINESE TRADITIONAL; MEMBRANE POTENTIALS; OSMOSIS; POTASSIUM CHANNEL BLOCKERS; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; RATS; RATS, WISTAR; SODIUM POTASSIUM CHLORIDE SYMPORTER INHIBITORS;

RATTUS;

EID: 77954955445     PISSN: 03788741     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jep.2010.05.018     Document Type: Article

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