Simultaneous quantification of multiple active components from Xiexin decoction in rat plasma by LC-ESI-MS/MS: Application in pharmacokinetics

Biomedical Chromatography

Volumn 25, Issue 7, 2011, Pages 816-826

  Zan, Bin ^a   Shi, Rong ^a   Wang, Tianming ^a   Wu, Jiasheng ^a   Ma, Yueming ^a   Cheng, Nengneng ^b  

^a SHANGHAI UNIVERSITY OF TRADITIONAL CHINESE MEDICINE   (China)

^b FUDAN UNIVERSITY   (China)

Author keywords

LC MS MS; Multiple components; Pharmacokinetics; Traditional Chinese medicine; Xiexin decoction

Indexed keywords

BODY FLUIDS; ELECTROSPRAY IONIZATION; FLAVONOIDS; ION SOURCES; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; MEDICINE; RATS;

COPTISINE; JATRORRHIZINE; LC-ESI-MS/MS; LC-MS-MS; LC.MS/MS; LC/ESI-MS/MS; MULTIPLE COMPONENTS; RAT PLASMA; TRADITIONAL CHINESE MEDICINE; XIEXIN DECOCTION;

PHARMACOKINETICS;

ALOEEMODIN; BAICALEIN; BAICALIN; BERBERINE; COPTISINE; EMODIN; JATRORRHIZINE; PALMATINE; PLANT EXTRACT; RHEIN; UNCLASSIFIED DRUG; WOGONIN; WOGONOSIDE; XIEXIN PLANT EXTRACT;

ACCURACY; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; ELECTROSPRAY MASS SPECTROMETRY; FEMALE; HUMAN; LIQUID CHROMATOGRAPHY; MALE; NEGATIVE ION ELECTROSPRAY; NONHUMAN; PLASMA; POSITIVE ION ELECTROSPRAY; RAT; SENSITIVITY AND SPECIFICITY;

RATTUS;

EID: 79958201852     PISSN: 02693879     EISSN: 10990801     Source Type: Journal    
DOI: 10.1002/bmc.1521     Document Type: Article

References (17)

1. Deng Y, Liao Q, Li S, Bi K, Pan B and Xie Z. Simultaneous determination of berberine, palmatine and jatrorrhizine by liquid chromatography-tandem mass spectrometry in rat plasma and its application in a pharmacokinetic study after oral administration of coptis-evodia herb couple. Journal of Chromatography B, Analytical Technologies in the Biomedical and Life Sciences 2008; 863: 195-205.
2. Kim YH, Jeong DW, Paek IB, Ji HY, Kim YC, Sohn DH and Lee HS. Liquid chromatography with tandem mass spectrometry for the simultaneous determination of baicalein, baicalin, oroxylin A and wogonin in rat plasma. Journal of Chromatography B, Analytical Technologies in the Biomedical and Life Sciences 2006; 844: 261-267.
3. Kim YH, Jeong DW, Kim YC, Sohn DH, Park ES and Lee HS. Pharmacokinetics of baicalein, baicalin and wogonin after oral administration of a standardized extract of Scutellaria baicalensis, PF-2405 in rats. Archives of Pharmacal Research 2007; 30: 260-265.
4. Li Y, Gao JP, Xu X and Dai LX. Simultaneous determination of baicalin, rhein and berberine in rat plasma by column-switching high-performance liquid chromatography. Journal of Chromatography B, Analytical Technologies in the Biomedical and Life Sciences 2006; 21: 50-55.
5. Lo YC, Tsai PL, Huang YB, Shen KP, Tsai YH, Wu YC, Lai YH and Chen IJ. San-Huang-Xie-Xin-Tang reduces lipopolysaccharides-induced hypotension and inflammatory mediators. Journal of Ethnopharmacology 2005; 96: 99-106.
6. Ma BL, Ma YM, Yan DM, Zhou H, Shi R, Wang TM, Yang Y, Wang CH and Zhang N. Effective constituents in Xiexin Decoction for anti-inflammation. Journal of Ethnopharmacology 2009; 125: 151-156.
7. Saegusa Y, Sugiyama A, Takahara A, Nagasawa Y and Hashimoto K. Relationship between phosphodiesterase inhibition induced by several Kampo medicines and smooth muscle relaxation of gastrointestinal tract tissues of rats. Journal of Pharmacological Sciences 2003; 93: 62-68.
8. Sanae F, Komatsu Y, Chisaki K, Kido T, Ishige A and Hayashi H. Effects of San'o-shashin-to and the constituent herbal medicines on theophylline-induced increase in arterial blood pressure of rats. Biological and Pharmaceutical Bulletin 2001; 24: 1137-1141.
9. Shah VP, Midha KK, Findlay JWA, Hill HM, Hulse JD, McGilveray IJ, McKay G, Miller KJ, .Patnaik RN, Powell ML, Tonelli A, Viswanathan CT and Yacobi A. Bioanalytical method validation-a revisit with a decade of progress. Pharmaceutical Research 2000; 17: 1551.
10. Shi R, Ma YM. Change of anthraquinones in Xiexin Decoction with different compatibilities. Chinese Traditional and Herbal Drugs 2007a; 38: 1327-1330.
11. Shi R, Ma YM. Study on contents of alkaloids and flavonoids in Xiexin Decoction with different combinations. Chinese Pharmaceutical Journal 2007b; 23: 1770-1773.
12. Tan B, Ma YM, Shi R and Wang TM. Simultaneous quantification of three alkaloids of Coptidis Rhizoma in rat urine by high-performance liquid chromatography: application to pharmacokinetic study. Biopharmaceutics and Drug Disposition 2007; 28: 511-516.
13. Xu F, Liu Y, Zhang Z, Song R, Dong H and Tian Y. Rapid simultaneous quantification of five active constituents in rat plasma by high-performance liquid chromatography/tandem mass spectrometry after oral administration of Da-Cheng-Qi decoction. Journal of Pharmaceutical and Biomedical Analysis 2008; 47: 586-595.
14. Yan DM and Ma YM. Simultaneous quantification of five anthraquinones in rat plasma by high-performance liquid chromatography with fluorescence detection. Biomedical Chromatography 2007; 21: 502-507.
15. Yan JC, Liu ZM, Wang TM, Shi R and Ma YM. Pharmacokinetics of flavonoids from xiexin decoction in rats. Yao Xue Xue Bao 2007; 42: 722-729.
16. Yu HH, Kim KJ, Cha JD, Kim HK, Lee YE, Choi NY and You YO. Antimicrobial activity of berberine alone and in combination with ampicillin or oxacillin against methicillin-resistant Staphylococcus aureus. Journal of Medicinal Food 2005; 8: 454-461.
17. Zuo F, Zhou ZM, Zhang Q, Mao D, Xiong YL, Wang YL, Yan MZ and Liu ML, Pharmacokinetic study on the multi-constituents of Huangqin-Tang decoction in rats. Biological and Pharmaceutical Bulletin 2003; 26911-26919.