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Volumn 26, Issue 3, 2014, Pages 399-412

Microcirculatory Alterations in Shock States

Author keywords

Blood flow; Cardiogenic shock; Hypovolemic shock; Microcirculation; Oxygen extraction; Oxygen transport; Oxygen utilization; Septic shock

Indexed keywords

OXYGEN;

EID: 84906775089     PISSN: 08995885     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ccell.2014.04.007     Document Type: Review
Times cited : (8)

References (94)
  • 1
    • 68049100316 scopus 로고    scopus 로고
    • Link between coagulation abnormalities and microcirculatory dysfunction in critically ill patients
    • De Backer D., Donadello K., Favory R. Link between coagulation abnormalities and microcirculatory dysfunction in critically ill patients. Curr Opin Anaesthesiol 2009, 22(2):150-154.
    • (2009) Curr Opin Anaesthesiol , vol.22 , Issue.2 , pp. 150-154
    • De Backer, D.1    Donadello, K.2    Favory, R.3
  • 2
    • 84860235381 scopus 로고    scopus 로고
    • Microcirculatory alterations: potential mechanisms and implications for therapy
    • De Backer D., Donadello K., Taccone F.S., et al. Microcirculatory alterations: potential mechanisms and implications for therapy. Ann Intensive Care 2011, 1(1):27.
    • (2011) Ann Intensive Care , vol.1 , Issue.1 , pp. 27
    • De Backer, D.1    Donadello, K.2    Taccone, F.S.3
  • 3
    • 27144502125 scopus 로고    scopus 로고
    • Clinical manifestations of disordered microcirculatory perfusion in severe sepsis
    • Trzeciak S., Rivers E.P. Clinical manifestations of disordered microcirculatory perfusion in severe sepsis. Crit Care 2005, 9(Suppl 4):S20-S26.
    • (2005) Crit Care , vol.9 , Issue.SUPPL. 4
    • Trzeciak, S.1    Rivers, E.P.2
  • 4
    • 4444233598 scopus 로고    scopus 로고
    • Persistent microcirculatory alterations are associated with organ failure and death in patients with septic shock
    • Sakr Y., Dubois M.J., De Backer D., et al. Persistent microcirculatory alterations are associated with organ failure and death in patients with septic shock. Crit Care Med 2004, 32(9):1825-1831.
    • (2004) Crit Care Med , vol.32 , Issue.9 , pp. 1825-1831
    • Sakr, Y.1    Dubois, M.J.2    De Backer, D.3
  • 5
    • 84874934644 scopus 로고    scopus 로고
    • Microcirculatory alterations in patients with severe sepsis: impact of time of assessment and relationship with outcome
    • De Backer D., Donadello K., Sakr Y., et al. Microcirculatory alterations in patients with severe sepsis: impact of time of assessment and relationship with outcome. Crit Care Med 2013, 41(3):791-799.
    • (2013) Crit Care Med , vol.41 , Issue.3 , pp. 791-799
    • De Backer, D.1    Donadello, K.2    Sakr, Y.3
  • 6
    • 27144553471 scopus 로고    scopus 로고
    • The microcirculation is the motor of sepsis
    • Ince C. The microcirculation is the motor of sepsis. Crit Care 2005, 9(Suppl 4):S13-S19.
    • (2005) Crit Care , vol.9 , Issue.SUPPL. 4
    • Ince, C.1
  • 7
    • 0141920370 scopus 로고    scopus 로고
    • Bench-to-bedside review: microvascular dysfunction in sepsis-hemodynamics, oxygen transport, and nitric oxide
    • Bateman R.M., Sharpe M.D., Ellis C.G. Bench-to-bedside review: microvascular dysfunction in sepsis-hemodynamics, oxygen transport, and nitric oxide. Crit Care 2003, 7(5):359-373.
    • (2003) Crit Care , vol.7 , Issue.5 , pp. 359-373
    • Bateman, R.M.1    Sharpe, M.D.2    Ellis, C.G.3
  • 8
    • 34547115685 scopus 로고    scopus 로고
    • Myocardial hypoxia-inducible HIF-1alpha, VEGF, and GLUT1 gene expression is associated with microvascular and ICAM-1 heterogeneity during endotoxemia
    • Bateman R.M., Tokunaga C., Kareco T., et al. Myocardial hypoxia-inducible HIF-1alpha, VEGF, and GLUT1 gene expression is associated with microvascular and ICAM-1 heterogeneity during endotoxemia. Am J Physiol Heart Circ Physiol 2007, 293(1):H448-H456.
    • (2007) Am J Physiol Heart Circ Physiol , vol.293 , Issue.1
    • Bateman, R.M.1    Tokunaga, C.2    Kareco, T.3
  • 9
    • 11344279695 scopus 로고    scopus 로고
    • Bench-to-bedside review: sepsis is a disease of the microcirculation
    • Spronk P.E., Zandstra D.F., Ince C. Bench-to-bedside review: sepsis is a disease of the microcirculation. Crit Care 2004, 8(6):462-468.
    • (2004) Crit Care , vol.8 , Issue.6 , pp. 462-468
    • Spronk, P.E.1    Zandstra, D.F.2    Ince, C.3
  • 10
    • 0036254948 scopus 로고    scopus 로고
    • Endothelial cell dysfunction and abnormal tissue perfusion
    • Vallet B. Endothelial cell dysfunction and abnormal tissue perfusion. Crit Care Med 2002, 30(Suppl 5):S229-S234.
    • (2002) Crit Care Med , vol.30 , Issue.SUPPL. 5
    • Vallet, B.1
  • 11
    • 0030854730 scopus 로고    scopus 로고
    • Endothelial dysfunction: does it matter? Is it reversible?
    • Celermajer D.S. Endothelial dysfunction: does it matter? Is it reversible?. JAm Coll Cardiol 1997, 30(2):325-333.
    • (1997) JAm Coll Cardiol , vol.30 , Issue.2 , pp. 325-333
    • Celermajer, D.S.1
  • 12
    • 77954116677 scopus 로고    scopus 로고
    • Endothelium and hemorheology
    • IOS Press, (WA), O.K. Baskurt, M.R. Hardeman, M.W. Rampling (Eds.)
    • Gori T., Forconi S. Endothelium and hemorheology. Handbook of hemorheology and hemodynamics 2007, 339-350. IOS Press, (WA). O.K. Baskurt, M.R. Hardeman, M.W. Rampling (Eds.).
    • (2007) Handbook of hemorheology and hemodynamics , pp. 339-350
    • Gori, T.1    Forconi, S.2
  • 13
    • 68049108421 scopus 로고    scopus 로고
    • The impact of the glycocalyx on microcirculatory oxygen distribution in critical illness
    • Chappell D., Westphal M., Jacob M. The impact of the glycocalyx on microcirculatory oxygen distribution in critical illness. Curr Opin Anaesthesiol 2009, 22(2):155-162.
    • (2009) Curr Opin Anaesthesiol , vol.22 , Issue.2 , pp. 155-162
    • Chappell, D.1    Westphal, M.2    Jacob, M.3
  • 14
    • 0031895415 scopus 로고    scopus 로고
    • Vascular reactivity and tissue oxygenation
    • Vallet B. Vascular reactivity and tissue oxygenation. Intensive Care Med 1998, 24(1):3-11.
    • (1998) Intensive Care Med , vol.24 , Issue.1 , pp. 3-11
    • Vallet, B.1
  • 15
    • 0033954313 scopus 로고    scopus 로고
    • Vasomotor control in arterioles of the mouse cremaster muscle
    • Hungerford J.E., Sessa W.C., Segal S.S. Vasomotor control in arterioles of the mouse cremaster muscle. FASEB J 2000, 14(1):197-207.
    • (2000) FASEB J , vol.14 , Issue.1 , pp. 197-207
    • Hungerford, J.E.1    Sessa, W.C.2    Segal, S.S.3
  • 16
    • 0035425503 scopus 로고    scopus 로고
    • Nitric oxide synthases: structure, function and inhibition
    • Alderton W.K., Cooper C.E., Knowles R.G. Nitric oxide synthases: structure, function and inhibition. Biochem J 2001, 357(Pt 3):593-615.
    • (2001) Biochem J , vol.357 , Issue.PART. 3 , pp. 593-615
    • Alderton, W.K.1    Cooper, C.E.2    Knowles, R.G.3
  • 17
    • 0027166309 scopus 로고
    • Platelet adhesion to human vascular endothelium is modulated by constitutive and cytokine induced nitric oxide
    • Radomski M.W., Vallance P., Whitley G., et al. Platelet adhesion to human vascular endothelium is modulated by constitutive and cytokine induced nitric oxide. Cardiovasc Res 1993, 27(7):1380-1382.
    • (1993) Cardiovasc Res , vol.27 , Issue.7 , pp. 1380-1382
    • Radomski, M.W.1    Vallance, P.2    Whitley, G.3
  • 18
    • 13844269298 scopus 로고    scopus 로고
    • The role of nitric oxide in cardiovascular diseases
    • Naseem K.M. The role of nitric oxide in cardiovascular diseases. Mol Aspects Med 2005, 26(1-2):33-65.
    • (2005) Mol Aspects Med , vol.26 , Issue.1-2 , pp. 33-65
    • Naseem, K.M.1
  • 19
    • 0027507615 scopus 로고
    • Interactions between neutrophils and endothelial cells
    • Godin C., Caprani A., Dufaux J., et al. Interactions between neutrophils and endothelial cells. JCell Sci 1993, 106(Pt 2):441-451.
    • (1993) JCell Sci , vol.106 , Issue.PART. 2 , pp. 441-451
    • Godin, C.1    Caprani, A.2    Dufaux, J.3
  • 20
    • 27544462651 scopus 로고    scopus 로고
    • Pathophysiology of sepsis: the role of nitric oxide
    • Kluwer Academic Publishers, Boston, J.L. Vincent, J. Carlet, S. Opal (Eds.)
    • Finney S.J., Evans T.W. Pathophysiology of sepsis: the role of nitric oxide. The sepsis text 2002, 211-229. Kluwer Academic Publishers, Boston. J.L. Vincent, J. Carlet, S. Opal (Eds.).
    • (2002) The sepsis text , pp. 211-229
    • Finney, S.J.1    Evans, T.W.2
  • 21
    • 0031892252 scopus 로고    scopus 로고
    • Prolonged inhibition of nitric oxide synthesis in severe septic shock: a clinical study
    • Avontuur J.A., Tutein Nolthenius R.P., van Bodegom J.W., et al. Prolonged inhibition of nitric oxide synthesis in severe septic shock: a clinical study. Crit Care Med 1998, 26(4):660-667.
    • (1998) Crit Care Med , vol.26 , Issue.4 , pp. 660-667
    • Avontuur, J.A.1    Tutein Nolthenius, R.P.2    van Bodegom, J.W.3
  • 22
    • 0027304372 scopus 로고
    • L-arginine pathway in the sepsis syndrome
    • Lorente J.A., Landin L., De Pablo R., et al. L-arginine pathway in the sepsis syndrome. Crit Care Med 1993, 21(9):1287-1295.
    • (1993) Crit Care Med , vol.21 , Issue.9 , pp. 1287-1295
    • Lorente, J.A.1    Landin, L.2    De Pablo, R.3
  • 23
    • 0028155913 scopus 로고
    • Effects of a nitric oxide synthase inhibitor in humans with septic shock
    • Petros A., Lamb G., Leone A., et al. Effects of a nitric oxide synthase inhibitor in humans with septic shock. Cardiovasc Res 1994, 28(1):34-39.
    • (1994) Cardiovasc Res , vol.28 , Issue.1 , pp. 34-39
    • Petros, A.1    Lamb, G.2    Leone, A.3
  • 24
    • 0026346162 scopus 로고
    • Effect of nitric oxide synthase inhibitors on hypotension in patients with septic shock
    • Petros A., Bennett D., Vallance P. Effect of nitric oxide synthase inhibitors on hypotension in patients with septic shock. Lancet 1991, 338(8782-8783):1557-1558.
    • (1991) Lancet , vol.338 , Issue.8782-8783 , pp. 1557-1558
    • Petros, A.1    Bennett, D.2    Vallance, P.3
  • 25
    • 0032832718 scopus 로고    scopus 로고
    • Differential alterations in systemic and regional oxygen delivery and consumption during the early and late stages of sepsis
    • Yang S., Cioffi W.G., Bland K.I., et al. Differential alterations in systemic and regional oxygen delivery and consumption during the early and late stages of sepsis. JTrauma 1999, 47(4):706-712.
    • (1999) JTrauma , vol.47 , Issue.4 , pp. 706-712
    • Yang, S.1    Cioffi, W.G.2    Bland, K.I.3
  • 26
    • 0030802620 scopus 로고    scopus 로고
    • Effects of nitric oxide on blood flow distribution and O2 extraction capabilities during endotoxic shock
    • Zhang H., Rogiers P., Smail N., et al. Effects of nitric oxide on blood flow distribution and O2 extraction capabilities during endotoxic shock. JAppl Phys 1997, 83(4):1164-1173.
    • (1997) JAppl Phys , vol.83 , Issue.4 , pp. 1164-1173
    • Zhang, H.1    Rogiers, P.2    Smail, N.3
  • 27
    • 0034222910 scopus 로고    scopus 로고
    • Tissue oxygenation and hemodynamic response to NO synthase inhibition in septic shock
    • Broccard A., Hurni J.M., Eckert P., et al. Tissue oxygenation and hemodynamic response to NO synthase inhibition in septic shock. Shock 2000, 14:35-40.
    • (2000) Shock , vol.14 , pp. 35-40
    • Broccard, A.1    Hurni, J.M.2    Eckert, P.3
  • 28
    • 50849095839 scopus 로고    scopus 로고
    • The microcirculation in health and critical disease
    • den Uil C.A., Klijn E., Lagrand W.K., et al. The microcirculation in health and critical disease. Prog Cardiovasc Dis 2008, 51(2):161-170.
    • (2008) Prog Cardiovasc Dis , vol.51 , Issue.2 , pp. 161-170
    • den Uil, C.A.1    Klijn, E.2    Lagrand, W.K.3
  • 29
    • 0034051945 scopus 로고    scopus 로고
    • Red blood cell regulation of microvascular tone through adenosine triphosphate
    • Dietrich H.H., Ellsworth M.L., Sprague R.S., et al. Red blood cell regulation of microvascular tone through adenosine triphosphate. Am J Physiol Heart Circ Physiol 2000, 278(4):H1294-H1298.
    • (2000) Am J Physiol Heart Circ Physiol , vol.278 , Issue.4
    • Dietrich, H.H.1    Ellsworth, M.L.2    Sprague, R.S.3
  • 30
    • 79954598581 scopus 로고    scopus 로고
    • Erythrocytes as controllers of perfusion distribution in the microvasculature of skeletal muscle
    • Sprague R.S., Bowles E.A., Achilleus D., et al. Erythrocytes as controllers of perfusion distribution in the microvasculature of skeletal muscle. Acta Physiol (Oxf) 2011, 202(3):285-292.
    • (2011) Acta Physiol (Oxf) , vol.202 , Issue.3 , pp. 285-292
    • Sprague, R.S.1    Bowles, E.A.2    Achilleus, D.3
  • 31
    • 0022597122 scopus 로고
    • Adual function for adenosine 5'-triphosphate in the regulation of vascular tone. Excitatory cotransmitter with noradrenaline from perivascular nerves and locally released inhibitory intravascular agent
    • Burnstock G., Kennedy C. Adual function for adenosine 5'-triphosphate in the regulation of vascular tone. Excitatory cotransmitter with noradrenaline from perivascular nerves and locally released inhibitory intravascular agent. Circ Res 1986, 58(3):319-330.
    • (1986) Circ Res , vol.58 , Issue.3 , pp. 319-330
    • Burnstock, G.1    Kennedy, C.2
  • 32
    • 0034115430 scopus 로고    scopus 로고
    • The red blood cell as an oxygen sensor: what is the evidence?
    • Ellsworth M.L. The red blood cell as an oxygen sensor: what is the evidence?. Acta Physiol Scand 2000, 168(4):551-559.
    • (2000) Acta Physiol Scand , vol.168 , Issue.4 , pp. 551-559
    • Ellsworth, M.L.1
  • 33
    • 0031843694 scopus 로고    scopus 로고
    • Conducted vascular responses: communication across the capillary bed
    • Collins D.M., McCullough W.T., Ellsworth M.L. Conducted vascular responses: communication across the capillary bed. Microvasc Res 1998, 56(1):43-53.
    • (1998) Microvasc Res , vol.56 , Issue.1 , pp. 43-53
    • Collins, D.M.1    McCullough, W.T.2    Ellsworth, M.L.3
  • 34
    • 27144432919 scopus 로고    scopus 로고
    • The microcirculation as a functional system
    • Ellis C.G., Jagger J., Sharpe M. The microcirculation as a functional system. Crit Care 2005, 9(Suppl 4):S3-S8.
    • (2005) Crit Care , vol.9 , Issue.SUPPL. 4
    • Ellis, C.G.1    Jagger, J.2    Sharpe, M.3
  • 35
    • 84875471761 scopus 로고    scopus 로고
    • From macrohemodynamic to the microcirculation
    • Donati A., Domizi R., Damiani E., et al. From macrohemodynamic to the microcirculation. Crit Care Res Pract 2013, 2013:892710.
    • (2013) Crit Care Res Pract , vol.2013 , pp. 892710
    • Donati, A.1    Domizi, R.2    Damiani, E.3
  • 36
    • 0035888676 scopus 로고    scopus 로고
    • Microcirculation in intestinal villi: a comparison between hemorrhagic and endotoxin shock
    • Nakajima Y., Baudry N., Duranteau J., et al. Microcirculation in intestinal villi: a comparison between hemorrhagic and endotoxin shock. Am J Respir Crit Care Med 2001, 164(8 Pt 1):1526-1530.
    • (2001) Am J Respir Crit Care Med , vol.164 , Issue.8 PART. 1 , pp. 1526-1530
    • Nakajima, Y.1    Baudry, N.2    Duranteau, J.3
  • 37
    • 84885023053 scopus 로고    scopus 로고
    • New insights into the pathophysiology of cardiogenic shock: the role of the microcirculation
    • Ashruf J.F., Bruining H.A., Ince C. New insights into the pathophysiology of cardiogenic shock: the role of the microcirculation. Curr Opin Crit Care 2013, 19(5):381-386.
    • (2013) Curr Opin Crit Care , vol.19 , Issue.5 , pp. 381-386
    • Ashruf, J.F.1    Bruining, H.A.2    Ince, C.3
  • 38
    • 79955629732 scopus 로고    scopus 로고
    • Targeting the microcirculation in resuscitation of acutely unwell patients
    • Harrois A., Dupic L., Duranteau J. Targeting the microcirculation in resuscitation of acutely unwell patients. Curr Opin Crit Care 2011, 17(3):303-307.
    • (2011) Curr Opin Crit Care , vol.17 , Issue.3 , pp. 303-307
    • Harrois, A.1    Dupic, L.2    Duranteau, J.3
  • 39
    • 77955811514 scopus 로고    scopus 로고
    • Withdrawing intra-aortic balloon pump support paradoxically improves microvascular flow
    • Munsterman L.D., Elbers P.W., Ozdemir A., et al. Withdrawing intra-aortic balloon pump support paradoxically improves microvascular flow. Crit Care 2010, 14(4):R161.
    • (2010) Crit Care , vol.14 , Issue.4
    • Munsterman, L.D.1    Elbers, P.W.2    Ozdemir, A.3
  • 40
    • 79955704469 scopus 로고    scopus 로고
    • Microcirculation in cardiogenic shock: from scientific bystander to therapy target
    • Jung C., Lauten A., Ferrari M. Microcirculation in cardiogenic shock: from scientific bystander to therapy target. Crit Care 2010, 14(5):193.
    • (2010) Crit Care , vol.14 , Issue.5 , pp. 193
    • Jung, C.1    Lauten, A.2    Ferrari, M.3
  • 41
    • 0347296030 scopus 로고    scopus 로고
    • Effects of epinephrine and norepinephrine on hemodynamics, oxidative metabolism, and organ energetics in endotoxemic rats
    • Levy B., Mansart A., Bollaert P.E., et al. Effects of epinephrine and norepinephrine on hemodynamics, oxidative metabolism, and organ energetics in endotoxemic rats. Intensive Care Med 2003, 29(2):292-300.
    • (2003) Intensive Care Med , vol.29 , Issue.2 , pp. 292-300
    • Levy, B.1    Mansart, A.2    Bollaert, P.E.3
  • 42
    • 84891656914 scopus 로고    scopus 로고
    • Pathophysiology of microcirculatory dysfunction and the pathogenesis of septic shock
    • De Backer D., Orbegozo Cortes D., Donadello K., et al. Pathophysiology of microcirculatory dysfunction and the pathogenesis of septic shock. Virulence 2013, 5(1):73-79.
    • (2013) Virulence , vol.5 , Issue.1 , pp. 73-79
    • De Backer, D.1    Orbegozo Cortes, D.2    Donadello, K.3
  • 43
    • 84906759352 scopus 로고    scopus 로고
    • Microvascular alterations in sepsis
    • Kluwer Academic Publishers, Boston, J.L. Vincent, J. Carlet, S. Opal (Eds.)
    • Sielenkamper A.W., Kvietys P., Sibbald W. Microvascular alterations in sepsis. The sepsis text 2002, 247-270. Kluwer Academic Publishers, Boston. J.L. Vincent, J. Carlet, S. Opal (Eds.).
    • (2002) The sepsis text , pp. 247-270
    • Sielenkamper, A.W.1    Kvietys, P.2    Sibbald, W.3
  • 44
    • 4444269296 scopus 로고    scopus 로고
    • Microcirculation in distress: a new resuscitation end point?
    • Ince C. Microcirculation in distress: a new resuscitation end point?. Crit Care Med 2004, 32(9):1963-1964.
    • (2004) Crit Care Med , vol.32 , Issue.9 , pp. 1963-1964
    • Ince, C.1
  • 45
    • 0037588986 scopus 로고    scopus 로고
    • The role of the endothelium in severe sepsis and multiple organ dysfunction syndrome
    • Aird W.C. The role of the endothelium in severe sepsis and multiple organ dysfunction syndrome. Blood 2003, 101(10):3765-3777.
    • (2003) Blood , vol.101 , Issue.10 , pp. 3765-3777
    • Aird, W.C.1
  • 46
    • 84860240248 scopus 로고    scopus 로고
    • Quantitative assessment of the microcirculation in healthy volunteers and in patients with septic shock
    • Edul V.S., Enrico C., Laviolle B., et al. Quantitative assessment of the microcirculation in healthy volunteers and in patients with septic shock. Crit Care Med 2012, 40(5):1443-1448.
    • (2012) Crit Care Med , vol.40 , Issue.5 , pp. 1443-1448
    • Edul, V.S.1    Enrico, C.2    Laviolle, B.3
  • 47
    • 0032790876 scopus 로고    scopus 로고
    • Microcirculatory oxygenation and shunting in sepsis and shock
    • Ince C., Sinaasappel M. Microcirculatory oxygenation and shunting in sepsis and shock. Crit Care Med 1999, 27(7):1369-1377.
    • (1999) Crit Care Med , vol.27 , Issue.7 , pp. 1369-1377
    • Ince, C.1    Sinaasappel, M.2
  • 48
    • 2942545798 scopus 로고    scopus 로고
    • Bidirectional relation between inflammation and coagulation
    • Levi M., van der Poll T., Buller H.R. Bidirectional relation between inflammation and coagulation. Circulation 2004, 109(22):2698-2704.
    • (2004) Circulation , vol.109 , Issue.22 , pp. 2698-2704
    • Levi, M.1    van der Poll, T.2    Buller, H.R.3
  • 50
    • 0029937134 scopus 로고    scopus 로고
    • Sepsis/septic shock: participation of the microcirculation: an abbreviated review
    • Hinshaw L.B. Sepsis/septic shock: participation of the microcirculation: an abbreviated review. Crit Care Med 1996, 24(6):1072-1078.
    • (1996) Crit Care Med , vol.24 , Issue.6 , pp. 1072-1078
    • Hinshaw, L.B.1
  • 51
    • 27144452656 scopus 로고    scopus 로고
    • Microvascular resuscitation as a therapeutic goal in severe sepsis
    • Bateman R.M., Walley K.R. Microvascular resuscitation as a therapeutic goal in severe sepsis. Crit Care 2005, 9(Suppl 4):S27-S32.
    • (2005) Crit Care , vol.9 , Issue.SUPPL. 4
    • Bateman, R.M.1    Walley, K.R.2
  • 52
    • 44049093984 scopus 로고    scopus 로고
    • Resuscitating the microcirculation in sepsis: the central role of nitric oxide, emerging concepts for novel therapies, and challenges for clinical trials
    • Trzeciak S., Cinel I., Phillip Dellinger R., et al. Resuscitating the microcirculation in sepsis: the central role of nitric oxide, emerging concepts for novel therapies, and challenges for clinical trials. Acad Emerg Med 2008, 15(5):399-413.
    • (2008) Acad Emerg Med , vol.15 , Issue.5 , pp. 399-413
    • Trzeciak, S.1    Cinel, I.2    Phillip Dellinger, R.3
  • 53
    • 82755186505 scopus 로고    scopus 로고
    • Year in review 2010: critical care-multiple organ dysfunction and sepsis
    • de Montmollin E., Annane D. Year in review 2010: critical care-multiple organ dysfunction and sepsis. Crit Care 2011, 15(6):236.
    • (2011) Crit Care , vol.15 , Issue.6 , pp. 236
    • de Montmollin, E.1    Annane, D.2
  • 54
    • 77952403329 scopus 로고    scopus 로고
    • Coupling microcirculation to systemic hemodynamics
    • De Backer D., Ortiz J.A., Salgado D. Coupling microcirculation to systemic hemodynamics. Curr Opin Crit Care 2010, 16(3):250-254.
    • (2010) Curr Opin Crit Care , vol.16 , Issue.3 , pp. 250-254
    • De Backer, D.1    Ortiz, J.A.2    Salgado, D.3
  • 55
    • 34249090606 scopus 로고    scopus 로고
    • Hepatic platelet and leukocyte adherence during endotoxemia
    • Croner R.S., Hoerer E., Kulu Y., et al. Hepatic platelet and leukocyte adherence during endotoxemia. Crit Care 2006, 10(1):R15.
    • (2006) Crit Care , vol.10 , Issue.1
    • Croner, R.S.1    Hoerer, E.2    Kulu, Y.3
  • 56
    • 42149084524 scopus 로고    scopus 로고
    • Endothelial glycocalyx damage during endotoxemia coincides with microcirculatory dysfunction and vascular oxidative stress
    • Marechal X., Favory R., Joulin O., et al. Endothelial glycocalyx damage during endotoxemia coincides with microcirculatory dysfunction and vascular oxidative stress. Shock 2008, 29(5):572-576.
    • (2008) Shock , vol.29 , Issue.5 , pp. 572-576
    • Marechal, X.1    Favory, R.2    Joulin, O.3
  • 57
    • 34447500485 scopus 로고    scopus 로고
    • Microvascular and capillary perfusion following glycocalyx degradation
    • Cabrales P., Vazquez B.Y., Tsai A.G., et al. Microvascular and capillary perfusion following glycocalyx degradation. JAppl Phys (1985) 2007, 102(6):2251-2259.
    • (2007) JAppl Phys (1985) , vol.102 , Issue.6 , pp. 2251-2259
    • Cabrales, P.1    Vazquez, B.Y.2    Tsai, A.G.3
  • 58
    • 54849433850 scopus 로고    scopus 로고
    • Increased levels of glycosaminoglycans during septic shock: relation to mortality and the antibacterial actions of plasma
    • Nelson A., Berkestedt I., Schmidtchen A., et al. Increased levels of glycosaminoglycans during septic shock: relation to mortality and the antibacterial actions of plasma. Shock 2008, 30(6):623-627.
    • (2008) Shock , vol.30 , Issue.6 , pp. 623-627
    • Nelson, A.1    Berkestedt, I.2    Schmidtchen, A.3
  • 59
    • 0038347425 scopus 로고    scopus 로고
    • Conducted vasoconstriction is reduced in a mouse model of sepsis
    • Lidington D., Ouellette Y., Li F., et al. Conducted vasoconstriction is reduced in a mouse model of sepsis. JVasc Res 2003, 40(2):149-158.
    • (2003) JVasc Res , vol.40 , Issue.2 , pp. 149-158
    • Lidington, D.1    Ouellette, Y.2    Li, F.3
  • 60
    • 0034822793 scopus 로고    scopus 로고
    • Lipopolysaccharide reduces intercellular coupling invitro and arteriolar conducted response invivo
    • Tyml K., Wang X., Lidington D., et al. Lipopolysaccharide reduces intercellular coupling invitro and arteriolar conducted response invivo. Am J Physiol Heart Circ Physiol 2001, 281(3):H1397-H1406.
    • (2001) Am J Physiol Heart Circ Physiol , vol.281 , Issue.3
    • Tyml, K.1    Wang, X.2    Lidington, D.3
  • 61
    • 0023408650 scopus 로고
    • Analysis of vascular pattern and dimensions in arteriolar networks of the retractor muscle in young hamsters
    • Ellsworth M.L., Liu A., Dawant B., et al. Analysis of vascular pattern and dimensions in arteriolar networks of the retractor muscle in young hamsters. Microvasc Res 1987, 34(2):168-183.
    • (1987) Microvasc Res , vol.34 , Issue.2 , pp. 168-183
    • Ellsworth, M.L.1    Liu, A.2    Dawant, B.3
  • 62
    • 0023198721 scopus 로고
    • Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor
    • Palmer R.M., Ferrige A.G., Moncada S. Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor. Nature 1987, 327(6122):524-526.
    • (1987) Nature , vol.327 , Issue.6122 , pp. 524-526
    • Palmer, R.M.1    Ferrige, A.G.2    Moncada, S.3
  • 63
    • 0028302512 scopus 로고
    • Differential induction of nitric oxide synthase in various organs of the mouse during endotoxaemia: role of TNF-alpha and IL-1-beta
    • Cunha F.Q., Assreuy J., Moss D.W., et al. Differential induction of nitric oxide synthase in various organs of the mouse during endotoxaemia: role of TNF-alpha and IL-1-beta. Immunology 1994, 81(2):211-215.
    • (1994) Immunology , vol.81 , Issue.2 , pp. 211-215
    • Cunha, F.Q.1    Assreuy, J.2    Moss, D.W.3
  • 64
    • 0031214709 scopus 로고    scopus 로고
    • Red blood cell aggregation in experimental sepsis
    • Baskurt O.K., Temiz A., Meiselman H.J. Red blood cell aggregation in experimental sepsis. JLab Clin Med 1997, 130(2):183-190.
    • (1997) JLab Clin Med , vol.130 , Issue.2 , pp. 183-190
    • Baskurt, O.K.1    Temiz, A.2    Meiselman, H.J.3
  • 65
    • 0031867470 scopus 로고    scopus 로고
    • Differential expression of inducible nitric oxide synthase messenger RNA along the longitudinal and crypt-villus axes of the intestine in endotoxemic rats
    • Morin M.J., Unno N., Hodin R.A., et al. Differential expression of inducible nitric oxide synthase messenger RNA along the longitudinal and crypt-villus axes of the intestine in endotoxemic rats. Crit Care Med 1998, 26(7):1258-1264.
    • (1998) Crit Care Med , vol.26 , Issue.7 , pp. 1258-1264
    • Morin, M.J.1    Unno, N.2    Hodin, R.A.3
  • 66
    • 0029809991 scopus 로고    scopus 로고
    • Endotoxic shock alters distribution of blood flow within the intestinal wall
    • Revelly J.P., Ayuse T., Brienza N., et al. Endotoxic shock alters distribution of blood flow within the intestinal wall. Crit Care Med 1996, 24(8):1345-1351.
    • (1996) Crit Care Med , vol.24 , Issue.8 , pp. 1345-1351
    • Revelly, J.P.1    Ayuse, T.2    Brienza, N.3
  • 67
    • 0028053865 scopus 로고
    • Microvascular perfusion is impaired in a rat model of normotensive sepsis
    • Lam C., Tyml K., Martin C., et al. Microvascular perfusion is impaired in a rat model of normotensive sepsis. JClin Invest 1994, 94(5):2077-2083.
    • (1994) JClin Invest , vol.94 , Issue.5 , pp. 2077-2083
    • Lam, C.1    Tyml, K.2    Martin, C.3
  • 68
    • 0030065143 scopus 로고    scopus 로고
    • Decreased capillary density invivo in bowel mucosa of rats with normotensive sepsis
    • Farquhar I., Martin C.M., Lam C., et al. Decreased capillary density invivo in bowel mucosa of rats with normotensive sepsis. JSurg Res 1996, 61(1):190-196.
    • (1996) JSurg Res , vol.61 , Issue.1 , pp. 190-196
    • Farquhar, I.1    Martin, C.M.2    Lam, C.3
  • 71
    • 0033943531 scopus 로고    scopus 로고
    • Endotoxin promotes adhesion of human erythrocytes to human vascular endothelial cells under conditions of flow
    • Eichelbronner O., Sielenkamper A., Cepinskas G., et al. Endotoxin promotes adhesion of human erythrocytes to human vascular endothelial cells under conditions of flow. Crit Care Med 2000, 28(6):1865-1870.
    • (2000) Crit Care Med , vol.28 , Issue.6 , pp. 1865-1870
    • Eichelbronner, O.1    Sielenkamper, A.2    Cepinskas, G.3
  • 72
    • 0029362668 scopus 로고
    • Capillary network morphology and capillary flow
    • Groom A.C., Ellis C.G., Wrigley S.J., et al. Capillary network morphology and capillary flow. Int J Microcirc Clin Exp 1995, 15(5):223-230.
    • (1995) Int J Microcirc Clin Exp , vol.15 , Issue.5 , pp. 223-230
    • Groom, A.C.1    Ellis, C.G.2    Wrigley, S.J.3
  • 73
    • 4444368823 scopus 로고    scopus 로고
    • Importance of platelets and fibrinogen in neutrophil-endothelial cell interactions in septic shock
    • Kirschenbaum L.A., McKevitt D., Rullan M., et al. Importance of platelets and fibrinogen in neutrophil-endothelial cell interactions in septic shock. Crit Care Med 2004, 32(9):1904-1909.
    • (2004) Crit Care Med , vol.32 , Issue.9 , pp. 1904-1909
    • Kirschenbaum, L.A.1    McKevitt, D.2    Rullan, M.3
  • 74
    • 78650414437 scopus 로고    scopus 로고
    • Impaired microvascular perfusion in sepsis requires activated coagulation and P-selectin-mediated platelet adhesion in capillaries
    • Secor D., Li F., Ellis C.G., et al. Impaired microvascular perfusion in sepsis requires activated coagulation and P-selectin-mediated platelet adhesion in capillaries. Intensive Care Med 2010, 36(11):1928-1934.
    • (2010) Intensive Care Med , vol.36 , Issue.11 , pp. 1928-1934
    • Secor, D.1    Li, F.2    Ellis, C.G.3
  • 75
    • 34250834405 scopus 로고    scopus 로고
    • Platelet count decline: an early prognostic marker incritically ill patients with prolonged ICU stays
    • Moreau D., Timsit J.F., Vesin A., et al. Platelet count decline: an early prognostic marker incritically ill patients with prolonged ICU stays. Chest 2007, 131(6):1735-1741.
    • (2007) Chest , vol.131 , Issue.6 , pp. 1735-1741
    • Moreau, D.1    Timsit, J.F.2    Vesin, A.3
  • 76
    • 0141465216 scopus 로고    scopus 로고
    • Vital organ blood flow during hyperdynamic sepsis
    • Di Giantomasso D., May C.N., Bellomo R. Vital organ blood flow during hyperdynamic sepsis. Chest 2003, 124(3):1053-1059.
    • (2003) Chest , vol.124 , Issue.3 , pp. 1053-1059
    • Di Giantomasso, D.1    May, C.N.2    Bellomo, R.3
  • 78
    • 0037010370 scopus 로고    scopus 로고
    • Nitroglycerin in septic shock after intravascular volume resuscitation
    • Spronk P.E., Ince C., Gardien M.J., et al. Nitroglycerin in septic shock after intravascular volume resuscitation. Lancet 2002, 360(9343):1395-1396.
    • (2002) Lancet , vol.360 , Issue.9343 , pp. 1395-1396
    • Spronk, P.E.1    Ince, C.2    Gardien, M.J.3
  • 79
    • 0036644655 scopus 로고    scopus 로고
    • Microvascular blood flow is altered in patients with sepsis
    • De Backer D., Creteur J., Preiser J.C., et al. Microvascular blood flow is altered in patients with sepsis. Am J Respir Crit Care Med 2002, 166(1):98-104.
    • (2002) Am J Respir Crit Care Med , vol.166 , Issue.1 , pp. 98-104
    • De Backer, D.1    Creteur, J.2    Preiser, J.C.3
  • 80
    • 0036079693 scopus 로고    scopus 로고
    • Effect of a maldistribution of microvascular blood flow on capillary O(2) extraction in sepsis
    • Ellis C.G., Bateman R.M., Sharpe M.D., et al. Effect of a maldistribution of microvascular blood flow on capillary O(2) extraction in sepsis. Am J Physiol Heart Circ Physiol 2002, 282(1):H156-H164.
    • (2002) Am J Physiol Heart Circ Physiol , vol.282 , Issue.1
    • Ellis, C.G.1    Bateman, R.M.2    Sharpe, M.D.3
  • 81
    • 80054740939 scopus 로고    scopus 로고
    • The role of renal hypoperfusion in development of renal microcirculatory dysfunction in endotoxemic rats
    • Legrand M., Bezemer R., Kandil A., et al. The role of renal hypoperfusion in development of renal microcirculatory dysfunction in endotoxemic rats. Intensive Care Med 2011, 37(9):1534-1542.
    • (2011) Intensive Care Med , vol.37 , Issue.9 , pp. 1534-1542
    • Legrand, M.1    Bezemer, R.2    Kandil, A.3
  • 82
    • 0029750207 scopus 로고    scopus 로고
    • Heterogeneity of oxygen delivery impairs oxygen extraction by peripheral tissues: theory
    • Walley K.R. Heterogeneity of oxygen delivery impairs oxygen extraction by peripheral tissues: theory. JAppl Phys (1985) 1996, 81(2):885-894.
    • (1996) JAppl Phys (1985) , vol.81 , Issue.2 , pp. 885-894
    • Walley, K.R.1
  • 83
    • 33744941056 scopus 로고    scopus 로고
    • Effect of decreased O2 supply on skeletal muscle oxygenation and O2 consumption during sepsis: role of heterogeneous capillary spacing and blood flow
    • Goldman D., Bateman R.M., Ellis C.G. Effect of decreased O2 supply on skeletal muscle oxygenation and O2 consumption during sepsis: role of heterogeneous capillary spacing and blood flow. Am J Physiol Heart Circ Physiol 2006, 290(6):H2277-H2285.
    • (2006) Am J Physiol Heart Circ Physiol , vol.290 , Issue.6
    • Goldman, D.1    Bateman, R.M.2    Ellis, C.G.3
  • 84
    • 0029746049 scopus 로고    scopus 로고
    • Heterogeneity of gut capillary transit times and impaired gut oxygen extraction in endotoxemic pigs
    • Humer M.F., Phang P.T., Friesen B.P., et al. Heterogeneity of gut capillary transit times and impaired gut oxygen extraction in endotoxemic pigs. JAppl Phys (1985) 1996, 81(2):895-904.
    • (1996) JAppl Phys (1985) , vol.81 , Issue.2 , pp. 895-904
    • Humer, M.F.1    Phang, P.T.2    Friesen, B.P.3
  • 85
    • 0022480082 scopus 로고
    • The coronary circulation in human septic shock
    • Cunnion R.E., Schaer G.L., Parker M.M., et al. The coronary circulation in human septic shock. Circulation 1986, 73(4):637-644.
    • (1986) Circulation , vol.73 , Issue.4 , pp. 637-644
    • Cunnion, R.E.1    Schaer, G.L.2    Parker, M.M.3
  • 86
    • 0023097510 scopus 로고
    • Coronary hemodynamics and myocardial metabolism of lactate, free fatty acids, glucose, and ketones in patients with septic shock
    • Dhainaut J.F., Huyghebaert M.F., Monsallier J.F., et al. Coronary hemodynamics and myocardial metabolism of lactate, free fatty acids, glucose, and ketones in patients with septic shock. Circulation 1987, 75(3):533-541.
    • (1987) Circulation , vol.75 , Issue.3 , pp. 533-541
    • Dhainaut, J.F.1    Huyghebaert, M.F.2    Monsallier, J.F.3
  • 87
    • 0027255030 scopus 로고
    • Oxygen consumption and resting metabolic rate in sepsis, sepsis syndrome, and septic shock
    • Kreymann G., Grosser S., Buggisch P., et al. Oxygen consumption and resting metabolic rate in sepsis, sepsis syndrome, and septic shock. Crit Care Med 1993, 21(7):1012-1019.
    • (1993) Crit Care Med , vol.21 , Issue.7 , pp. 1012-1019
    • Kreymann, G.1    Grosser, S.2    Buggisch, P.3
  • 88
    • 0037142987 scopus 로고    scopus 로고
    • Association between mitochondrial dysfunction and severity and outcome of septic shock
    • Brealey D., Brand M., Hargreaves I., et al. Association between mitochondrial dysfunction and severity and outcome of septic shock. Lancet 2002, 360(9328):219-223.
    • (2002) Lancet , vol.360 , Issue.9328 , pp. 219-223
    • Brealey, D.1    Brand, M.2    Hargreaves, I.3
  • 89
    • 0024598020 scopus 로고
    • Oxygen delivery and uptake by peripheral tissues: physiology and pathophysiology
    • Schumacker P.T., Samsel R.W. Oxygen delivery and uptake by peripheral tissues: physiology and pathophysiology. Crit Care Clin 1989, 5(2):255-269.
    • (1989) Crit Care Clin , vol.5 , Issue.2 , pp. 255-269
    • Schumacker, P.T.1    Samsel, R.W.2
  • 90
    • 0028132781 scopus 로고
    • Altered mitochondrial redox responses in gram negative septic shock in primates
    • Simonson S.G., Welty-Wolf K., Huang Y.T., et al. Altered mitochondrial redox responses in gram negative septic shock in primates. Circ Shock 1994, 43(1):34-43.
    • (1994) Circ Shock , vol.43 , Issue.1 , pp. 34-43
    • Simonson, S.G.1    Welty-Wolf, K.2    Huang, Y.T.3
  • 91
    • 0026012502 scopus 로고
    • Peripheral oxygen availability within skeletal muscle in sepsis and septic shock: comparison to limited infection and cardiogenic shock
    • Boekstegers P., Weidenhofer S., Pilz G., et al. Peripheral oxygen availability within skeletal muscle in sepsis and septic shock: comparison to limited infection and cardiogenic shock. Infection 1991, 19(5):317-323.
    • (1991) Infection , vol.19 , Issue.5 , pp. 317-323
    • Boekstegers, P.1    Weidenhofer, S.2    Pilz, G.3
  • 92
    • 0027740037 scopus 로고
    • Absence of supply dependence of oxygen consumption in patients with septic shock
    • Manthous C.A., Schumacker P.T., Pohlman A., et al. Absence of supply dependence of oxygen consumption in patients with septic shock. JCrit Care 1993, 8(4):203-211.
    • (1993) JCrit Care , vol.8 , Issue.4 , pp. 203-211
    • Manthous, C.A.1    Schumacker, P.T.2    Pohlman, A.3
  • 93
    • 36248992450 scopus 로고    scopus 로고
    • Sidestream Dark Field (SDF) imaging: a novel stroboscopic LED ring-based imaging modality for clinical assessment of the microcirculation
    • Goedhart P.T., Khalilzada M., Bezemer R., et al. Sidestream Dark Field (SDF) imaging: a novel stroboscopic LED ring-based imaging modality for clinical assessment of the microcirculation. Opt Express 2007, 15(23):15101-15114.
    • (2007) Opt Express , vol.15 , Issue.23 , pp. 15101-15114
    • Goedhart, P.T.1    Khalilzada, M.2    Bezemer, R.3
  • 94
    • 84896730375 scopus 로고    scopus 로고
    • Microcirculatory effects of the transfusion of leukodepleted or non-leukodepleted red blood cells in septic patients: a pilot study
    • Donati A., Damiani E., Luchetti M.M., et al. Microcirculatory effects of the transfusion of leukodepleted or non-leukodepleted red blood cells in septic patients: a pilot study. Crit Care 2014, 18(1):R33.
    • (2014) Crit Care , vol.18 , Issue.1
    • Donati, A.1    Damiani, E.2    Luchetti, M.M.3


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