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Volumn 26, Issue 4, 1998, Pages 660-667

Prolonged inhibition of nitric oxide synthesis in severe septic shock: A clinical study

Author keywords

Analogs of; Catecholamines; Hypotension; Inhibitors of; Intensive care; L NAME; L arginine; Mortality; Nitric oxide; Nitric oxide synthesis; Septic shock

Indexed keywords

N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE;

EID: 0031892252     PISSN: 00903493     EISSN: None     Source Type: Journal    
DOI: 10.1097/00003246-199804000-00012     Document Type: Article
Times cited : (104)

References (37)
  • 1
    • 0027920980 scopus 로고
    • Pathogenetic mechanisms of septic shock
    • Parrillo JE: Pathogenetic mechanisms of septic shock. N Engl J Med 1993; 328:953-963
    • (1993) N Engl J Med , vol.328 , pp. 953-963
    • Parrillo, J.E.1
  • 2
    • 0025883342 scopus 로고
    • Nitric oxide: Physiology, pathophysiology, and pharmacology
    • Moncada S, Palmer RM, Higgs EA: Nitric oxide: Physiology, pathophysiology, and pharmacology. Pharmacol Rev 1991; 43:109-142
    • (1991) Pharmacol Rev , vol.43 , pp. 109-142
    • Moncada, S.1    Palmer, R.M.2    Higgs, E.A.3
  • 3
    • 0023912670 scopus 로고
    • Vascular endothelial cells synthesize nitric oxide from L-arginine
    • Palmer RM, Ashton DS, Moncada S: Vascular endothelial cells synthesize nitric oxide from L-arginine. Nature 1988; 333:664-666
    • (1988) Nature , vol.333 , pp. 664-666
    • Palmer, R.M.1    Ashton, D.S.2    Moncada, S.3
  • 4
    • 0030769929 scopus 로고    scopus 로고
    • Nitric oxide causes dysfunction of coronary autoregulation in endotoxemic rats
    • Avontuur JA, Bruining HA, Ince C: Nitric oxide causes dysfunction of coronary autoregulation in endotoxemic rats. Cardiovasc Res 1997; 35:368-376
    • (1997) Cardiovasc Res , vol.35 , pp. 368-376
    • Avontuur, J.A.1    Bruining, H.A.2    Ince, C.3
  • 5
    • 0025011716 scopus 로고
    • Characterisation of three inhibitors of endothelial nitric oxide synthase in vitro and in vivo
    • Rees DD, Palmer RM, Schulz R, et al: Characterisation of three inhibitors of endothelial nitric oxide synthase in vitro and in vivo. Br J Pharmacol 1990; 101:746-752
    • (1990) Br J Pharmacol , vol.101 , pp. 746-752
    • Rees, D.D.1    Palmer, R.M.2    Schulz, R.3
  • 7
    • 0025195627 scopus 로고
    • G-methyl-L-arginine inhibits tumor necrosis factor-induced hypotension: Implications for the involvement of nitric oxide
    • G-methyl-L-arginine inhibits tumor necrosis factor-induced hypotension: Implications for the involvement of nitric oxide. Proc Natl Acad Sci U S A 1990; 87:3629-3632
    • (1990) Proc Natl Acad Sci U S A , vol.87 , pp. 3629-3632
    • Kilbourn, R.G.1    Jubran, A.2    Gross, S.S.3
  • 8
    • 0026729192 scopus 로고
    • Reversal of hyperdynamic responses to continuous endotoxin administration by inhibition of NO synthesis
    • Meyer J, Traber LD, Nelson S, et al: Reversal of hyperdynamic responses to continuous endotoxin administration by inhibition of NO synthesis. J Appl Physiol 1992; 73:324-328
    • (1992) J Appl Physiol , vol.73 , pp. 324-328
    • Meyer, J.1    Traber, L.D.2    Nelson, S.3
  • 9
    • 0027304372 scopus 로고
    • L-arginine pathway in the sepsis syndrome
    • Lorente JA, Landin L, De Pablo R, et al: L-arginine pathway in the sepsis syndrome. Crit Care Med 1993; 21:1287-1295
    • (1993) Crit Care Med , vol.21 , pp. 1287-1295
    • Lorente, J.A.1    Landin, L.2    De Pablo, R.3
  • 10
    • 0028155913 scopus 로고
    • Effects of a nitric oxide synthase inhibitor in humans with septic shock
    • Petros A, Lamb G, Leone A, et al: Effects of a nitric oxide synthase inhibitor in humans with septic shock. Cardiovasc Res 1994; 28:34-39
    • (1994) Cardiovasc Res , vol.28 , pp. 34-39
    • Petros, A.1    Lamb, G.2    Leone, A.3
  • 11
    • 0028872983 scopus 로고
    • Methylene blue administration in septic shock: A clinical trial
    • Preiser JC, Lejeune P, Roman A, et al: Methylene blue administration in septic shock: A clinical trial. Crit Care Med 1995; 23:259-264
    • (1995) Crit Care Med , vol.23 , pp. 259-264
    • Preiser, J.C.1    Lejeune, P.2    Roman, A.3
  • 12
    • 0026334414 scopus 로고
    • Inhibition of nitric oxide synthesis in septic shock: How much is beneficial?
    • Nava E, Palmer RM, Moncada S: Inhibition of nitric oxide synthesis in septic shock: How much is beneficial? Lancet 1991; 338:1555-1557
    • (1991) Lancet , vol.338 , pp. 1555-1557
    • Nava, E.1    Palmer, R.M.2    Moncada, S.3
  • 13
    • 0028877340 scopus 로고
    • Nitric oxide inhibition in the treatment of septic shock
    • Hata JS, Dellinger RP: Nitric oxide inhibition in the treatment of septic shock. Crit Care Med 1995; 23:1621-1624
    • (1995) Crit Care Med , vol.23 , pp. 1621-1624
    • Hata, J.S.1    Dellinger, R.P.2
  • 14
    • 0024333745 scopus 로고
    • The sepsis syndrome: A valid clinical entity
    • Bone RC, Fischer CJ, Clemmer TP, et al: The sepsis syndrome: A valid clinical entity. Crit Care Med 1989; 17:389-393
    • (1989) Crit Care Med , vol.17 , pp. 389-393
    • Bone, R.C.1    Fischer, C.J.2    Clemmer, T.P.3
  • 15
    • 0026611509 scopus 로고
    • G-nitro-arginine methyl ester in the anesthetized rabbit: Venous vasomotion and plasma levels
    • G-nitro-arginine methyl ester in the anesthetized rabbit: Venous vasomotion and plasma levels. J Vasc Res 1992; 29:290-292
    • (1992) J Vasc Res , vol.29 , pp. 290-292
    • Schwarzacher, S.1    Raberger, G.L.2
  • 16
    • 0022256529 scopus 로고
    • APACHE II: A severity of disease classification system
    • Knaus WA, Le Gall JR, Wagner DP, et al: APACHE II: A severity of disease classification system. Crit Care Med 1985; 13:818-829
    • (1985) Crit Care Med , vol.13 , pp. 818-829
    • Knaus, W.A.1    Le Gall, J.R.2    Wagner, D.P.3
  • 18
    • 0027141432 scopus 로고
    • Aminoguanidine selectively inhibits inducible nitric oxide synthase
    • Griffiths MJ, Messent M, Mac Allister RJ, et al: Aminoguanidine selectively inhibits inducible nitric oxide synthase. Br J Pharmacol 1993; 110:963-968
    • (1993) Br J Pharmacol , vol.110 , pp. 963-968
    • Griffiths, M.J.1    Messent, M.2    Mac Allister, R.J.3
  • 19
    • 0027528798 scopus 로고
    • Anticytokine strategies in the treatment of the systemic inflammatory response syndrome
    • Dinarello CA, Gelfand JA, Wolff SM: Anticytokine strategies in the treatment of the systemic inflammatory response syndrome. JAMA 1993; 269:1829-1835
    • (1993) JAMA , vol.269 , pp. 1829-1835
    • Dinarello, C.A.1    Gelfand, J.A.2    Wolff, S.M.3
  • 20
    • 0001509578 scopus 로고
    • Mammalian nitrate biosynthesis: Mouse macrophages produce nitrite and nitrate in response to Escherichia coli lipopolysaccharide
    • Stuehr DJ, Marietta MA: Mammalian nitrate biosynthesis: Mouse macrophages produce nitrite and nitrate in response to Escherichia coli lipopolysaccharide. Proc Natl Acad Sci U S A 1985; 82:7738-7742
    • (1985) Proc Natl Acad Sci U S A , vol.82 , pp. 7738-7742
    • Stuehr, D.J.1    Marietta, M.A.2
  • 21
    • 0029031661 scopus 로고
    • Direct measurement of nitric oxide in human beings
    • Vallance P, Patton S, Bhagat K, et al: Direct measurement of nitric oxide in human beings. Lancet 1995; 345: 153-154
    • (1995) Lancet , vol.345 , pp. 153-154
    • Vallance, P.1    Patton, S.2    Bhagat, K.3
  • 23
    • 0027053340 scopus 로고
    • Nitric oxide production within cardiac myocytes reduces their contractility in endotoxemia
    • Brady JB, Poole-Wilson PA, Harding SE, et al: Nitric oxide production within cardiac myocytes reduces their contractility in endotoxemia. Am J Physiol 1992; 263:H1963-H1966
    • (1992) Am J Physiol , vol.263
    • Brady, J.B.1    Poole-Wilson, P.A.2    Harding, S.E.3
  • 24
    • 0028895671 scopus 로고
    • Inhibition of nitric oxide synthesis causes myocardial ischemia in endotoxemic rats
    • Avontuur JA, Bruining HA, Ince C: Inhibition of nitric oxide synthesis causes myocardial ischemia in endotoxemic rats. Circ Res 1995; 76: 418-425
    • (1995) Circ Res , vol.76 , pp. 418-425
    • Avontuur, J.A.1    Bruining, H.A.2    Ince, C.3
  • 25
    • 0025200266 scopus 로고
    • G-methyl-L-arginine inhibits endotoxin-induced nitrite/ nitrate biosynthesis while promoting hepatic damage
    • G-methyl-L-arginine inhibits endotoxin-induced nitrite/ nitrate biosynthesis while promoting hepatic damage. J Leukoc Biol 1990; 48:565-569
    • (1990) J Leukoc Biol , vol.48 , pp. 565-569
    • Billiar, R.T.1    Curran, R.D.2    Harbrecht, B.D.3
  • 26
    • 0026570471 scopus 로고
    • Protective and pathological roles of nitric oxide in endotoxin shock
    • Wright CE, Rees DD, Moncada S: Protective and pathological roles of nitric oxide in endotoxin shock. Cardiovasc Res 1992; 26:48-57
    • (1992) Cardiovasc Res , vol.26 , pp. 48-57
    • Wright, C.E.1    Rees, D.D.2    Moncada, S.3
  • 27
    • 0027055199 scopus 로고
    • Inhibition of nitric oxide synthesis improves survival in a murine peritonitis model of sepsis and that is not cured by antibiotics alone
    • Teale DM, Akinson AM: Inhibition of nitric oxide synthesis improves survival in a murine peritonitis model of sepsis and that is not cured by antibiotics alone. J Antimicrob Chemother 1992; 30:839-842
    • (1992) J Antimicrob Chemother , vol.30 , pp. 839-842
    • Teale, D.M.1    Akinson, A.M.2
  • 28
    • 0027476883 scopus 로고
    • Nitric oxide-mediated hyporeactivity to noradrenaline precedes the induction of nitric oxide synthase in endotoxin shock
    • Szabo C, Mitchell JA, Thiemermann C, et al: Nitric oxide-mediated hyporeactivity to noradrenaline precedes the induction of nitric oxide synthase in endotoxin shock. Br J Pharmacol 1993; 108:786-792
    • (1993) Br J Pharmacol , vol.108 , pp. 786-792
    • Szabo, C.1    Mitchell, J.A.2    Thiemermann, C.3
  • 29
    • 0030014263 scopus 로고    scopus 로고
    • Differential regulation of the constitutive and inducible nitric oxide synthase mRNA by lipopolysaccharide treatment in vivo in the rat
    • Liu SF, Adcock IM, Old RW, et al: Differential regulation of the constitutive and inducible nitric oxide synthase mRNA by lipopolysaccharide treatment in vivo in the rat. Crit Care Med 1996; 24:1219-1225
    • (1996) Crit Care Med , vol.24 , pp. 1219-1225
    • Liu, S.F.1    Adcock, I.M.2    Old, R.W.3
  • 30
    • 0026518402 scopus 로고
    • Gastric intramucosal pH as a therapeutic index of tissue oxygenation in critically ill patients
    • Gutierrez G, Palizas F, Doglio G, et al: Gastric intramucosal pH as a therapeutic index of tissue oxygenation in critically ill patients. Lancet 1992; 339:195-199
    • (1992) Lancet , vol.339 , pp. 195-199
    • Gutierrez, G.1    Palizas, F.2    Doglio, G.3
  • 31
    • 0023200487 scopus 로고
    • Endogenous nitric oxide inhibits human platelet adhesion to vascular endothelium
    • Radomski MW, Palmer RM, Moncada S: Endogenous nitric oxide inhibits human platelet adhesion to vascular endothelium. Lancet 1987; ii:1057-1058
    • (1987) Lancet , vol.2 , pp. 1057-1058
    • Radomski, M.W.1    Palmer, R.M.2    Moncada, S.3
  • 32
    • 0026016313 scopus 로고
    • The role of nitric oxide as an endogenous regulator of platelet and neutrophil activation within the pulmonary circulation of the rabbit
    • May GR, Crook P, Moore PK, et al: The role of nitric oxide as an endogenous regulator of platelet and neutrophil activation within the pulmonary circulation of the rabbit. Br J Pharmacol 1991; 102:759-763
    • (1991) Br J Pharmacol , vol.102 , pp. 759-763
    • May, G.R.1    Crook, P.2    Moore, P.K.3
  • 33
    • 0025731835 scopus 로고
    • Nitric oxide: An endogenous modulator of leukocyte adhesion
    • Kubes P, Suzuki M, Granger DN: Nitric oxide: An endogenous modulator of leukocyte adhesion. Proc Natl acad Sci U S A 1991; 88:4651-1655
    • (1991) Proc Natl Acad Sci U S A , vol.88 , pp. 4651-11655
    • Kubes, P.1    Suzuki, M.2    Granger, D.N.3
  • 34
    • 0027389250 scopus 로고
    • Inhaled nitric oxide for the adult respiratory distress syndrome
    • Rossaint R, Falke KJ, Slama K, et al: Inhaled nitric oxide for the adult respiratory distress syndrome. N Engl J Med 1993; 328:399-405
    • (1993) N Engl J Med , vol.328 , pp. 399-405
    • Rossaint, R.1    Falke, K.J.2    Slama, K.3
  • 35
    • 0026002659 scopus 로고
    • Inhaled nitric oxide as a cause of selective pulmonary vasodilatation in pulmonary hypertension
    • Pepke-Zaba J, Higenbottam TW, Dinh-Xuan AT, et al: Inhaled nitric oxide as a cause of selective pulmonary vasodilatation in pulmonary hypertension. Lancet 1991; 338:1173-1174
    • (1991) Lancet , vol.338 , pp. 1173-1174
    • Pepke-Zaba, J.1    Higenbottam, T.W.2    Dinh-Xuan, A.T.3
  • 36
    • 0026672628 scopus 로고
    • Endogenous endothelium-derived relaxing factor opposes hypoxic pulmonary vasoconstriction and supports blood flow to hypoxic alveoli in anesthetized rabbits
    • Sprague RS, Thiemermann C, Vane JR: Endogenous endothelium-derived relaxing factor opposes hypoxic pulmonary vasoconstriction and supports blood flow to hypoxic alveoli in anesthetized rabbits. Proc Natl Acad Sci USA 1992; 89:8711-8715
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 8711-8715
    • Sprague, R.S.1    Thiemermann, C.2    Vane, J.R.3


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