Planar cell polarity gene mutations contribute to the etiology of human neural tube defects in our population

Birth Defects Research Part A - Clinical and Molecular Teratology

Volumn 100, Issue 8, 2014, Pages 633-641

  De Marco, Patrizia ^a   Merello, Elisa ^a   Piatelli, Gianluca ^a   Cama, Armando ^a   Kibar, Zoha ^b   Capra, Valeria ^a  

^a G GASLINI INSTITUTE   (Italy)

^b UNIVERSITÉ DE MONTRÉAL   (Canada)

Author keywords

CELSR1 gene; FUZZY gene; FZD3 and FZD6 genes; LRP6 gene; Neural tube defects (NTDs); Planar cell polarity pathway (PCP); PRICKLE gene; VANGL1 and VANGL2 genes

Indexed keywords

CELSR1 PROTEIN; DISHEVELLED PROTEIN; FRIZZLED PROTEIN; FUZZY PROTEIN; LOW DENSITY LIPOPROTEIN RECEPTOR RELATED PROTEIN 6; PRICKLE1 PROTEIN; PROTEIN; UNCLASSIFIED DRUG; VANGL1 PROTEIN; DISHEVELLED PROTEINS; PHOSPHOPROTEIN; SIGNAL TRANSDUCING ADAPTOR PROTEIN; WNT PROTEIN;

ACTIN FILAMENT; CELL POLARITY; CELLULAR DISTRIBUTION; CELSR1 GENE; DISEASE TRANSMISSION; DROSOPHILA; FUZZY GENE; GENE INTERACTION; GENE MUTATION; GENETIC ANALYSIS; GENETIC VARIABILITY; GENOTYPE PHENOTYPE CORRELATION; HUMAN; MAMMAL; MISSENSE MUTATION; NEURAL TUBE DEFECT; NONHUMAN; PATHOGENESIS; PLANAR CELL POLARITY; POPULATION; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; REVIEW; SIGNAL TRANSDUCTION; VANGL1 GENE; EMBRYOLOGY; GENETICS; MUTATION; NEURAL TUBE; NEURULATION; WNT SIGNALING PATHWAY;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; CELL POLARITY; FRIZZLED RECEPTORS; HUMANS; MUTATION; NEURAL TUBE; NEURAL TUBE DEFECTS; NEURULATION; PHOSPHOPROTEINS; WNT PROTEINS; WNT SIGNALING PATHWAY;

EID: 84906493735     PISSN: 15420752     EISSN: 15420760     Source Type: Journal    
DOI: 10.1002/bdra.23255     Document Type: Review

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