Generation of Lrp6 conditional gene-targeting mouse line for modeling and dissecting multiple birth defects/congenital anomalies

Developmental Dynamics

Volumn 239, Issue 1, 2010, Pages 318-326

  Zhou, Chengji J ^a   Wang, Ya Zhou ^a   Yamagami, Takashi ^a   Zhao, Tianyu ^a   Song, Lanying ^a   Wang, Kai ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Birth defects; Canonical Wnt catenin signaling pathway; Cleft lip; Conditional gene targeting; Congenital diseases; External genitalia; Limb defects; LoxP Cre; Lrp6; Microphthalmia; Neural tube defects; Ocular coloboma; Oligodactyly; Spina bifida

Indexed keywords

LOW DENSITY LIPOPROTEIN RECEPTOR RELATED PROTEIN 6;

AGENESIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIRTH; BIRTH DEFECT; BRAIN MALFORMATION; CLEFT PALATE; CONGENITAL HEART MALFORMATION; CONGENITAL MALFORMATION; CONTROLLED STUDY; DEATH; DISEASE MODEL; EMBRYO; EXON; EYE MALFORMATION; FEMALE; GENE; GENE DELETION; GENE TARGETING; GENITAL MALFORMATION; HOMOZYGOTE; LIMB DEFECT; LOXP SITE; LRP6 GENE; MALE; MOUSE; NEURAL TUBE DEFECT; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROPHYLAXIS;

ANIMALS; BLOTTING, NORTHERN; CONGENITAL ABNORMALITIES; CROSSES, GENETIC; DISEASE MODELS, ANIMAL; DNA PRIMERS; ELECTROPORATION; EXONS; GENE TARGETING; IMMUNOBLOTTING; LDL-RECEPTOR RELATED PROTEINS; MICE; MICROINJECTIONS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

MUS;

EID: 73949155182     PISSN: 10588388     EISSN: 10970177     Source Type: Journal    
DOI: 10.1002/dvdy.22054     Document Type: Article

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