-
1
-
-
34548683483
-
Heterogeneity and cell-fate decisions in effector and memory CD8+ T cell differentiation during viral infection
-
Kaech, S.M. & Wherry, E.J. Heterogeneity and cell-fate decisions in effector and memory CD8+ T cell differentiation during viral infection. Immunity 27, 393-405 (2007).
-
(2007)
Immunity
, vol.27
, pp. 393-405
-
-
Kaech, S.M.1
Wherry, E.J.2
-
2
-
-
80051873375
-
CD8+ T cells: Foot soldiers of the immune system
-
Zhang, N. & Bevan, M.J. CD8+ T cells: foot soldiers of the immune system. Immunity 35, 161-168 (2011).
-
(2011)
Immunity
, vol.35
, pp. 161-168
-
-
Zhang, N.1
Bevan, M.J.2
-
3
-
-
84878831880
-
Posttranscriptional control of T cell effector function by aerobic glycolysis
-
Chang, C.H. et al. Posttranscriptional control of T cell effector function by aerobic glycolysis. Cell 153, 1239-1251 (2013).
-
(2013)
Cell
, vol.153
, pp. 1239-1251
-
-
Chang, C.H.1
-
4
-
-
84867896903
-
Transcriptional control of effector and memory CD8+ T cell differentiation
-
Kaech, S.M. & Cui, W. Transcriptional control of effector and memory CD8+ T cell differentiation. Nat. Rev. Immunol. 12, 749-761 (2012).
-
(2012)
Nat. Rev. Immunol.
, vol.12
, pp. 749-761
-
-
Kaech, S.M.1
Cui, W.2
-
5
-
-
84875494365
-
Metabolic regulation of T lymphocytes
-
MacIver, N.J., Michalek, R.D. & Rathmell, J.C. Metabolic regulation of T lymphocytes. Annu. Rev. Immunol. 31, 259-283 (2013).
-
(2013)
Annu. Rev. Immunol.
, vol.31
, pp. 259-283
-
-
Maciver, N.J.1
Michalek, R.D.2
Rathmell, J.C.3
-
6
-
-
84865285455
-
Metabolic switching and fuel choice during T-cell differentiation and memory development
-
van der Windt, G.J. & Pearce, E.L. Metabolic switching and fuel choice during T-cell differentiation and memory development. Immunol. Rev. 249, 27-42 (2012).
-
(2012)
Immunol. Rev.
, vol.249
, pp. 27-42
-
-
Van Der Windt, G.J.1
Pearce, E.L.2
-
7
-
-
84865294745
-
Metabolic reprogramming and metabolic dependency in T cells
-
Wang, R. & Green, D.R. Metabolic reprogramming and metabolic dependency in T cells. Immunol. Rev. 249, 14-26 (2012).
-
(2012)
Immunol. Rev.
, vol.249
, pp. 14-26
-
-
Wang, R.1
Green, D.R.2
-
8
-
-
77957757417
-
A Myc network accounts for similarities between embryonic stem and cancer cell transcription programs
-
Kim, J. et al. A Myc network accounts for similarities between embryonic stem and cancer cell transcription programs. Cell 143, 313-324 (2010).
-
(2010)
Cell
, vol.143
, pp. 313-324
-
-
Kim, J.1
-
9
-
-
84867010006
-
C-Myc is a universal amplifier of expressed genes in lymphocytes and embryonic stem cells
-
Nie, Z. et al. c-Myc is a universal amplifier of expressed genes in lymphocytes and embryonic stem cells. Cell 151, 68-79 (2012).
-
(2012)
Cell
, vol.151
, pp. 68-79
-
-
Nie, Z.1
-
10
-
-
84867021989
-
Transcriptional amplification in tumor cells with elevated c-Myc
-
Lin, C.Y. et al. Transcriptional amplification in tumor cells with elevated c-Myc. Cell 151, 56-67 (2012).
-
(2012)
Cell
, vol.151
, pp. 56-67
-
-
Lin, C.Y.1
-
11
-
-
77951920690
-
C-Myc regulates transcriptional pause release
-
Rahl, P.B. et al. c-Myc regulates transcriptional pause release. Cell 141, 432-445 (2010).
-
(2010)
Cell
, vol.141
, pp. 432-445
-
-
Rahl, P.B.1
-
12
-
-
84876514626
-
Control of amino-acid transport by antigen receptors coordinates the metabolic reprogramming essential for T cell differentiation
-
Sinclair, L.V. et al. Control of amino-acid transport by antigen receptors coordinates the metabolic reprogramming essential for T cell differentiation. Nat. Immunol. 14, 500-508 (2013).
-
(2013)
Nat. Immunol.
, vol.14
, pp. 500-508
-
-
Sinclair, L.V.1
-
13
-
-
84255199079
-
The transcription factor Myc controls metabolic reprogramming upon T lymphocyte activation
-
Wang, R. et al. The transcription factor Myc controls metabolic reprogramming upon T lymphocyte activation. Immunity 35, 871-882 (2011).
-
(2011)
Immunity
, vol.35
, pp. 871-882
-
-
Wang, R.1
-
14
-
-
0035348175
-
Memory CD8+ T cell differentiation: Initial antigen encounter triggers a developmental program in naive cells
-
Kaech, S.M. & Ahmed, R. Memory CD8+ T cell differentiation: initial antigen encounter triggers a developmental program in naive cells. Nat. Immunol. 2, 415-422 (2001).
-
(2001)
Nat. Immunol
, vol.2
, pp. 415-422
-
-
Kaech, S.M.1
Ahmed, R.2
-
15
-
-
33748448910
-
Duration of the initial TCR stimulus controls the magnitude but not functionality of the CD8+ T cell response
-
Prlic, M., Hernandez-Hoyos, G. & Bevan, M.J. Duration of the initial TCR stimulus controls the magnitude but not functionality of the CD8+ T cell response. J. Exp. Med. 203, 2135-2143 (2006).
-
(2006)
J. Exp. Med.
, vol.203
, pp. 2135-2143
-
-
Prlic, M.1
Hernandez-Hoyos, G.2
Bevan, M.J.3
-
16
-
-
80052665758
-
Duration of antigen availability influences the expansion and memory differentiation of T cells
-
Blair, D.A. et al. Duration of antigen availability influences the expansion and memory differentiation of T cells. J. Immunol. 187, 2310-2321 (2011).
-
(2011)
J. Immunol.
, vol.187
, pp. 2310-2321
-
-
Blair, D.A.1
-
17
-
-
33644763937
-
The onset of CD8+-T-cell contraction is influenced by the peak of Listeria monocytogenes infection and antigen display
-
Porter, B.B. & Harty, J.T. The onset of CD8+-T-cell contraction is influenced by the peak of Listeria monocytogenes infection and antigen display. Infect. Immun. 74, 1528-1536 (2006).
-
(2006)
Infect. Immun.
, vol.74
, pp. 1528-1536
-
-
Porter, B.B.1
Harty, J.T.2
-
18
-
-
84875448616
-
Transcriptional insights into the CD8+ T cell response to infection and memory T cell formation
-
Best, J.A. et al. Transcriptional insights into the CD8+ T cell response to infection and memory T cell formation. Nat. Immunol. 14, 404-412 (2013).
-
(2013)
Nat. Immunol.
, vol.14
, pp. 404-412
-
-
Best, J.A.1
-
19
-
-
33745224089
-
Interleukin-2 signals during priming are required for secondary expansion of CD8+ memory T cells
-
Williams, M.A., Tyznik, A.J. & Bevan, M.J. Interleukin-2 signals during priming are required for secondary expansion of CD8+ memory T cells. Nature 441, 890-893 (2006).
-
(2006)
Nature
, vol.441
, pp. 890-893
-
-
Williams, M.A.1
Tyznik, A.J.2
Bevan, M.J.3
-
20
-
-
74549156399
-
CD4+ T cell regulation of CD25 expression controls development of short-lived effector CD8+ T cells in primary and secondary responses
-
Obar, J.J. et al. CD4+ T cell regulation of CD25 expression controls development of short-lived effector CD8+ T cells in primary and secondary responses. Proc. Natl. Acad. Sci. USA 107, 193-198 (2010).
-
(2010)
Proc. Natl. Acad. Sci. USA
, vol.107
, pp. 193-198
-
-
Obar, J.J.1
-
21
-
-
0345447666
-
IL-2 is not required for the initiation of CD8 T cell cycling but sustains expansion
-
D'Souza, W.N. & Lefrancois, L. IL-2 is not required for the initiation of CD8 T cell cycling but sustains expansion. J. Immunol. 171, 5727-5735 (2003).
-
(2003)
J. Immunol
, vol.171
, pp. 5727-5735
-
-
D'souza, W.N.1
Lefrancois, L.2
-
22
-
-
74549162832
-
Prolonged interleukin-2Rαexpression on virus-specific CD8+ T cells favors terminal-effector differentiation in vivo
-
Kalia, V. et al. Prolonged interleukin-2Rαexpression on virus-specific CD8+ T cells favors terminal-effector differentiation in vivo. Immunity 32, 91-103 (2010).
-
(2010)
Immunity
, vol.32
, pp. 91-103
-
-
Kalia, V.1
-
23
-
-
74549216531
-
Interleukin-2 and inflammation induce distinct transcriptional programs that promote the differentiation of effector cytolytic T cells
-
Pipkin, M.E. et al. Interleukin-2 and inflammation induce distinct transcriptional programs that promote the differentiation of effector cytolytic T cells. Immunity 32, 79-90 (2010).
-
(2010)
Immunity
, vol.32
, pp. 79-90
-
-
Pipkin, M.E.1
-
24
-
-
80052557419
-
Transcription factor AP4 modulates reversible and epigenetic silencing of the Cd4 gene
-
Egawa, T. & Littman, D.R. Transcription factor AP4 modulates reversible and epigenetic silencing of the Cd4 gene. Proc. Natl. Acad. Sci. USA 108, 14873-14878 (2011).
-
(2011)
Proc. Natl. Acad. Sci. USA
, vol.108
, pp. 14873-14878
-
-
Egawa, T.1
Littman, D.R.2
-
25
-
-
0025052367
-
Transcription factor AP-4 contains multiple dimerization domains that regulate dimer specificity
-
Hu, Y.F., Luscher, B., Admon, A., Mermod, N. & Tjian, R. Transcription factor AP-4 contains multiple dimerization domains that regulate dimer specificity. Genes Dev. 4, 1741-1752 (1990).
-
(1990)
Genes Dev.
, vol.4
, pp. 1741-1752
-
-
Hu, Y.F.1
Luscher, B.2
Admon, A.3
Mermod, N.4
Tjian, R.5
-
26
-
-
0023888953
-
Enhancer binding factors AP-4 and AP-1 act in concert to activate SV40 late transcription in vitro
-
Mermod, N., Williams, T.J. & Tjian, R. Enhancer binding factors AP-4 and AP-1 act in concert to activate SV40 late transcription in vitro. Nature 332, 557-561 (1988).
-
(1988)
Nature
, vol.332
, pp. 557-561
-
-
Mermod, N.1
Williams, T.J.2
Tjian, R.3
-
27
-
-
0024307348
-
Tolerance induction in double specific T-cell receptor transgenic mice varies with antigen
-
Pircher, H., Burki, K., Lang, R., Hengartner, H. & Zinkernagel, R.M. Tolerance induction in double specific T-cell receptor transgenic mice varies with antigen. Nature 342, 559-561 (1989).
-
(1989)
Nature
, vol.342
, pp. 559-561
-
-
Pircher, H.1
Burki, K.2
Lang, R.3
Hengartner, H.4
Zinkernagel, R.M.5
-
28
-
-
52549130987
-
Notch2 integrates signaling by the transcription factors RBP-J and CREB1 to promote T cell cytotoxicity
-
Maekawa, Y. et al. Notch2 integrates signaling by the transcription factors RBP-J and CREB1 to promote T cell cytotoxicity. Nat. Immunol. 9, 1140-1147 (2008).
-
(2008)
Nat. Immunol.
, vol.9
, pp. 1140-1147
-
-
Maekawa, Y.1
-
29
-
-
78149490549
-
The cell cycle time of CD8+ T cells responding in vivo is controlled by the type of antigenic stimulus
-
Yoon, H., Kim, T.S. & Braciale, T.J. The cell cycle time of CD8+ T cells responding in vivo is controlled by the type of antigenic stimulus. PLoS ONE 5, e15423 (2010).
-
(2010)
PLoS ONE
, vol.5
-
-
Yoon, H.1
Kim, T.S.2
Braciale, T.J.3
-
30
-
-
84867174742
-
Unpredictable and difficult to control-The adolescence of West Nile virus
-
Petersen, L.R. & Fischer, M. Unpredictable and difficult to control-the adolescence of West Nile virus. N. Engl. J. Med. 367, 1281-1284 (2012).
-
(2012)
N. Engl. J. Med.
, vol.367
, pp. 1281-1284
-
-
Petersen, L.R.1
Fischer, M.2
-
31
-
-
84872436774
-
West Nile virus infection and immunity
-
Suthar, M.S., Diamond, M.S. & Gale, M. Jr. West Nile virus infection and immunity. Nat. Rev. Microbiol. 11, 115-128 (2013).
-
(2013)
Nat. Rev. Microbiol.
, vol.11
, pp. 115-128
-
-
Suthar, M.S.1
Diamond, M.S.2
Gale Jr., M.3
-
32
-
-
3242677841
-
Role of CD8+ T cells in control of West Nile virus infection
-
Shrestha, B. & Diamond, M.S. Role of CD8+ T cells in control of West Nile virus infection. J. Virol. 78, 8312-8321 (2004).
-
(2004)
J. Virol.
, vol.78
, pp. 8312-8321
-
-
Shrestha, B.1
Diamond, M.S.2
-
33
-
-
84866562625
-
Metabolic checkpoints in activated T cells
-
Wang, R. & Green, D.R. Metabolic checkpoints in activated T cells. Nat. Immunol. 13, 907-915 (2012).
-
(2012)
Nat. Immunol.
, vol.13
, pp. 907-915
-
-
Wang, R.1
Green, D.R.2
-
34
-
-
54449095611
-
AP4 encodes a c-MYC-inducible repressor of p21
-
Jung, P., Menssen, A., Mayr, D. & Hermeking, H. AP4 encodes a c-MYC-inducible repressor of p21. Proc. Natl. Acad. Sci. USA 105, 15046-15051 (2008).
-
(2008)
Proc. Natl. Acad. Sci. USA
, vol.105
, pp. 15046-15051
-
-
Jung, P.1
Menssen, A.2
Mayr, D.3
Hermeking, H.4
-
35
-
-
42249101428
-
Dynamic regulation of c-Myc proto-oncogene expression during lymphocyte development revealed by a GFP-c-Myc knock-in mouse
-
Huang, C.Y.B.A.L., Walker, L.M., Bassing, C.H. & Sleckman, B.P. Dynamic regulation of c-Myc proto-oncogene expression during lymphocyte development revealed by a GFP-c-Myc knock-in mouse. Eur. J. Immunol. 38, 342-349 (2008).
-
(2008)
Eur. J. Immunol.
, vol.38
, pp. 342-349
-
-
Huang, C.Y.B.A.L.1
Walker, L.M.2
Bassing, C.H.3
Sleckman, B.P.4
-
36
-
-
84856183120
-
Mitochondrial respiratory capacity is a critical regulator of CD8+ T cell memory development
-
van der Windt, G.J. et al. Mitochondrial respiratory capacity is a critical regulator of CD8+ T cell memory development. Immunity 36, 68-78 (2012).
-
(2012)
Immunity
, vol.36
, pp. 68-78
-
-
Van Der Windt, G.J.1
-
37
-
-
84868010349
-
Revisiting global gene expression analysis
-
Lovén, J. et al. Revisiting global gene expression analysis. Cell 151, 476-482 (2012).
-
(2012)
Cell
, vol.151
, pp. 476-482
-
-
Lovén, J.1
-
38
-
-
0034037132
-
The c-Myc transactivation domain is a direct modulator of apoptotic versus proliferative signals
-
Chang, D.W., Claassen, G.F., Hann, S.R. & Cole, M.D. The c-Myc transactivation domain is a direct modulator of apoptotic versus proliferative signals. Mol. Cell. Biol. 20, 4309-4319 (2000).
-
(2000)
Mol. Cell. Biol.
, vol.20
, pp. 4309-4319
-
-
Chang, D.W.1
Claassen, G.F.2
Hann, S.R.3
Cole, M.D.4
-
39
-
-
2342526543
-
A signalling pathway controlling c-Myc degradation that impacts oncogenic transformation of human cells
-
Yeh, E. et al. A signalling pathway controlling c-Myc degradation that impacts oncogenic transformation of human cells. Nat. Cell Biol. 6, 308-318 (2004).
-
(2004)
Nat. Cell Biol.
, vol.6
, pp. 308-318
-
-
Yeh, E.1
-
40
-
-
0035129209
-
Analysis of C-MYC function in normal cells via conditional gene-targeted mutation
-
de Alboran, I.M. et al. Analysis of C-MYC function in normal cells via conditional gene-targeted mutation. Immunity 14, 45-55 (2001).
-
(2001)
Immunity
, vol.14
, pp. 45-55
-
-
De Alboran, I.M.1
-
41
-
-
33846899456
-
Restoration of p53 function leads to tumour regression in vivo
-
Ventura, A. et al. Restoration of p53 function leads to tumour regression in vivo. Nature 445, 661-665 (2007).
-
(2007)
Nature
, vol.445
, pp. 661-665
-
-
Ventura, A.1
-
42
-
-
62249131518
-
Complete but curtailed T-cell response to very low-affinity antigen
-
Zehn, D., Lee, S.Y. & Bevan, M.J. Complete but curtailed T-cell response to very low-affinity antigen. Nature 458, 211-214 (2009).
-
(2009)
Nature
, vol.458
, pp. 211-214
-
-
Zehn, D.1
Lee, S.Y.2
Bevan, M.J.3
-
43
-
-
0028178784
-
T cell receptor antagonist peptides induce positive selection
-
Hogquist, K.A. et al. T cell receptor antagonist peptides induce positive selection. Cell 76, 17-27 (1994).
-
(1994)
Cell
, vol.76
, pp. 17-27
-
-
Hogquist, K.A.1
-
44
-
-
0026485046
-
Mutations in T-cell antigen receptor genes αand βblock thymocyte development at different stages
-
Mombaerts, P. et al. Mutations in T-cell antigen receptor genes αand βblock thymocyte development at different stages. Nature 360, 225-231 (1992).
-
(1992)
Nature
, vol.360
, pp. 225-231
-
-
Mombaerts, P.1
-
45
-
-
0028784289
-
Interleukin-2 receptor αchain regulates the size and content of the peripheral lymphoid compartment
-
Willerford, D.M. et al. Interleukin-2 receptor αchain regulates the size and content of the peripheral lymphoid compartment. Immunity 3, 521-530 (1995).
-
(1995)
Immunity
, vol.3
, pp. 521-530
-
-
Willerford, D.M.1
-
46
-
-
0034046944
-
Plat-E: An efficient and stable system for transient packaging of retroviruses
-
Morita, S., Kojima, T. & Kitamura, T. Plat-E: an efficient and stable system for transient packaging of retroviruses. Gene Ther. 7, 1063-1066 (2000).
-
(2000)
Gene Ther.
, vol.7
, pp. 1063-1066
-
-
Morita, S.1
Kojima, T.2
Kitamura, T.3
-
47
-
-
0037316303
-
A comparison of normalization methods for high density oligonucleotide array data based on variance and bias
-
Bolstad, B.M., Irizarry, R.A., Astrand, M. & Speed, T.P. A comparison of normalization methods for high density oligonucleotide array data based on variance and bias. Bioinformatics 19, 185-193 (2003).
-
(2003)
Bioinformatics
, vol.19
, pp. 185-193
-
-
Bolstad, B.M.1
Irizarry, R.A.2
Astrand, M.3
Speed, T.P.4
-
48
-
-
84867581744
-
A validated regulatory network for Th17 cell specification
-
Ciofani, M. et al. A validated regulatory network for Th17 cell specification. Cell 151, 289-303 (2012).
-
(2012)
Cell
, vol.151
, pp. 289-303
-
-
Ciofani, M.1
-
49
-
-
84859210032
-
Fast gapped-read alignment with Bowtie 2
-
Langmead, B. & Salzberg, S.L. Fast gapped-read alignment with Bowtie 2. Nat. Methods 9, 357-359 (2012).
-
(2012)
Nat. Methods
, vol.9
, pp. 357-359
-
-
Langmead, B.1
Salzberg, S.L.2
-
50
-
-
77952567987
-
Simple combinations of lineage-determining transcription factors prime cis-regulatory elements required for macrophage and B cell identities
-
Heinz, S. et al. Simple combinations of lineage-determining transcription factors prime cis-regulatory elements required for macrophage and B cell identities. Mol. Cell 38, 576-589 (2010).
-
(2010)
Mol. Cell
, vol.38
, pp. 576-589
-
-
Heinz, S.1
|