Effects of one-time apple juice ingestion on the pharmacokinetics of fexofenadine enantiomers

European Journal of Clinical Pharmacology

Volumn 70, Issue 9, 2014, Pages 1087-1095

  Akamine, Yumiko ^a,b   Miura, Masatomo ^c   Komori, Hisakazu ^d   Saito, Shun ^d   Kusuhara, Hiroyuki ^e   Tamai, Ikumi ^d   Ieiri, Ichiro ^b   Uno, Tsukasa ^a   Yasui Furukori, Norio ^f  

^a UNIVERSITY OF THE RYUKYUS   (Japan)

^b KYUSHU UNIVERSITY   (Japan)

^c AKITA UNIVERSITY HOSPITAL   (Japan)

^d KANAZAWA UNIVERSITY   (Japan)

^e UNIVERSITY OF TOKYO   (Japan)

^f HIROSAKI UNIVERSITY   (Japan)

Author keywords

Apple juice; Enantiomer; Fexofenadine; OATP2B1; Pharmacokinetics

Indexed keywords

COMPLEMENTARY RNA; FEXOFENADINE; ORGANIC ANION TRANSPORTER B; ANTIALLERGIC AGENT; HISTAMINE H1 RECEPTOR ANTAGONIST; ORGANIC ANION TRANSPORTER; SLCO2B1 PROTEIN, HUMAN; TERFENADINE;

ADULT; ANIMAL TISSUE; APPLE JUICE; AREA UNDER THE CURVE; ARTICLE; CONTROLLED STUDY; CROSSOVER PROCEDURE; DRUG ABSORPTION; DRUG BLOOD LEVEL; DRUG EXCRETION; ENANTIOMER; FEMALE; FLUID INTAKE; HUMAN; IN VITRO STUDY; JAPANESE (PEOPLE); KIDNEY CLEARANCE; MALE; MAXIMUM PLASMA CONCENTRATION; NONHUMAN; NORMAL HUMAN; OOCYTE; OPEN STUDY; PLASMA CONCENTRATION-TIME CURVE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RANDOMIZED CONTROLLED TRIAL; STEREOCHEMISTRY; TIME TO MAXIMUM PLASMA CONCENTRATION; URINARY EXCRETION; ANALOGS AND DERIVATIVES; ANIMAL; BEVERAGE; BLOOD; CHEMISTRY; EATING; FOOD DRUG INTERACTION; FRUIT; GENETICS; INTESTINE ABSORPTION; MALUS; METABOLISM; STEREOISOMERISM; URINE; XENOPUS LAEVIS; YOUNG ADULT;

ADULT; ANIMALS; ANTI-ALLERGIC AGENTS; AREA UNDER CURVE; BEVERAGES; CROSS-OVER STUDIES; EATING; FEMALE; FOOD-DRUG INTERACTIONS; FRUIT; HISTAMINE H1 ANTAGONISTS, NON-SEDATING; HUMANS; INTESTINAL ABSORPTION; MALE; MALUS; OOCYTES; ORGANIC ANION TRANSPORTERS; RNA, COMPLEMENTARY; STEREOISOMERISM; TERFENADINE; XENOPUS LAEVIS; YOUNG ADULT;

EID: 84906262772     PISSN: 00316970     EISSN: 14321041     Source Type: Journal    
DOI: 10.1007/s00228-014-1705-y     Document Type: Article

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