Major active components in grapefruit, orange, and apple juices responsible for OATP2B1-mediated drug interactions

Journal of Pharmaceutical Sciences

Volumn 102, Issue 9, 2013, Pages 3418-3426

  Shirasaka, Yoshiyuki ^a   Shichiri, Megumi ^a   Mori, Takanori ^a   Nakanishi, Takeo ^a   Tamai, Ikumi ^a  

^a KANAZAWA UNIVERSITY   (Japan)

Author keywords

Apple juice; Flavonoid; Food interactions; Grapefruit juice; Interaction; Intestinal absorption; Intestinal secretion transport; OATP2B1; Orange juice; Organic anion transporting polypeptide transporters

Indexed keywords

6'7' DIHYDROXYBERGAMOTTIN; AURANTIIN; BERGAMOTTIN; ESTRONE SULFATE; FLAVONOID; HESPERETIN; HESPERIDIN; KAEMPFEROL; NARINGENIN; ORGANIC ANION TRANSPORTER 2; PHLORETIN; PHLORIZIN; QUERCETIN; UNCLASSIFIED DRUG;

APPLE JUICE; ARTICLE; CONCENTRATION (PARAMETERS); DRUG ABSORPTION; DRUG UPTAKE; FOOD DRUG INTERACTION; GRAPEFRUIT JUICE; IC 50; IN VITRO STUDY; NONHUMAN; OOCYTE; ORANGE JUICE; PROTEIN EXPRESSION; XENOPUS;

APPLE JUICE; FLAVONOID; FOOD INTERACTIONS; GRAPEFRUIT JUICE; INTERACTION; INTESTINAL ABSORPTION; INTESTINAL SECRETION/TRANSPORT; OATP2B1; ORANGE JUICE; ORGANIC ANION-TRANSPORTING POLYPEPTIDE TRANSPORTERS;

ANIMALS; BEVERAGES; CITRUS PARADISI; CITRUS SINENSIS; ESTRONE; FLAVONOIDS; FOOD-DRUG INTERACTIONS; GENE EXPRESSION; INTESTINAL ABSORPTION; MALUS; ORGANIC ANION TRANSPORTERS; XENOPUS;

EID: 84881567695     PISSN: 00223549     EISSN: 15206017     Source Type: Journal    
DOI: 10.1002/jps.23653     Document Type: Article

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