A feedback regulatory loop between HIF-1α and miR-21 in response to hypoxia in cardiomyocytes

FEBS Letters

Volumn 588, Issue 17, 2014, Pages 3137-3146

  Liu, Yang ^a,b   Nie, Honggang ^a,b   Zhang, Kuikui ^c   Ma, Dan ^a,b   Yang, Guang ^a   Zheng, Zhilei ^a   Liu, Kai ^a,b   Yu, Bo ^a,b   Zhai, Changlin ^d   Yang, Shuang ^a,b  

^a HARBIN MEDICAL UNIVERSITY   (China)

^b Key Laboratories of Education Ministry for Myocardial Ischemia Mechanism and Treatment   (China)

^c University of Chinese Medicine   (China)

^d JIAXING UNIVERSITY   (China)

Author keywords

Cardiomyocytes; Hypoxia; Hypoxia inducible factor 1 (HIF 1 ); MicroRNA; miR 21

Indexed keywords

HISTONE ACETYLTRANSFERASE PCAF; HYPOXIA INDUCIBLE FACTOR 1ALPHA; MICRORNA 21; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN BCL 2; PROTEIN KINASE B;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL HYPOXIA; CONTROLLED STUDY; ENZYME PHOSPHORYLATION; FEEDBACK SYSTEM; GENE ACTIVITY; GENE EXPRESSION; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; HEART MUSCLE CELL; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DNA BINDING; PROTEIN TRANSPORT;

CARDIOMYOCYTES; HYPOXIA; HYPOXIA-INDUCIBLE FACTOR 1Α (HIF-1Α); MICRORNA; MIR-21;

ANIMALS; APOPTOSIS; CELL HYPOXIA; CELL LINE; COBALT; FEEDBACK, PHYSIOLOGICAL; GENE EXPRESSION REGULATION; GENE SILENCING; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; MICE; MICRORNAS; MYOCYTES, CARDIAC; P300-CBP TRANSCRIPTION FACTORS; PHOSPHORYLATION; PROMOTER REGIONS, GENETIC; PROTO-ONCOGENE PROTEINS C-AKT; PROTO-ONCOGENE PROTEINS C-BCL-2; PTEN PHOSPHOHYDROLASE; TRANSCRIPTION, GENETIC;

EID: 84906247961     PISSN: 00145793     EISSN: 18733468     Source Type: Journal    
DOI: 10.1016/j.febslet.2014.05.067     Document Type: Article

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