Over-expression of microRNA-494 up-regulates hypoxia-inducible factor-1 alpha expression via PI3K/Akt pathway and protects against hypoxia-induced apoptosis

Journal of Biomedical Science

Volumn 20, Issue 1, 2013, Pages

  Sun, Guixiang ^a   Zhou, Yanni ^a   Li, Hongsheng ^a   Guo, Yingjia ^a   Shan, Juan ^a   Xia, Mengjuan ^a   Li, Youping ^a   Li, Shengfu ^a   Long, Dan ^a   Feng, Li ^a  

^a SICHUAN UNIVERSITY   (China)

Author keywords

Apoptosis; Hypoxia inducible factor 1 alpha; L02 cells; MicroRNA 494; PI3K Akt

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; CASPASE 3; CASPASE 7; HYPOXIA INDUCIBLE FACTOR 1ALPHA; LIPOCORTIN 5; MICRORNA; MICRORNA 494; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; UNCLASSIFIED DRUG; HIF1A PROTEIN, HUMAN; MIRN494 MICRORNA, HUMAN;

APOPTOSIS; ARTICLE; CELL HYPOXIA; CONTROLLED STUDY; ENZYME ACTIVITY; GENE OVEREXPRESSION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; LIVER CELL; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; UPREGULATION; WESTERN BLOTTING; ANAEROBIC GROWTH; CELL LINE; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; REAL TIME POLYMERASE CHAIN REACTION;

ANAEROBIOSIS; APOPTOSIS; BLOTTING, WESTERN; CELL LINE; GENE EXPRESSION REGULATION; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; MICRORNAS; PHOSPHATIDYLINOSITOL 3-KINASES; PROTO-ONCOGENE PROTEINS C-AKT; REAL-TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; UP-REGULATION;

EID: 84890601138     PISSN: 10217770     EISSN: 14230127     Source Type: Journal    
DOI: 10.1186/1423-0127-20-100     Document Type: Article

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