MiR-490-3p modulates cell growth and epithelial to mesenchymal transition of hepatocellular carcinoma cells by targeting endoplasmic reticulum-golgi intermediate compartment protein 3 (ERGIC3)

Journal of Biological Chemistry

Volumn 288, Issue 6, 2013, Pages 4035-4047

  Zhang, Ling Yun ^a   Liu, Min ^a   Li, Xin ^a   Tang, Hua ^a  

^a TIANJIN MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL PROCESS; CANCER METASTASIS; CELLULAR RESPONSE; EPITHELIAL TO MESENCHYMAL TRANSITIONS; HCC TISSUES; HEPATOCELLULAR CARCINOMA; HEPATOCELLULAR CARCINOMA CELL; KEY FACTORS; MICRORNAS; OVER-EXPRESSION; PROTEIN LEVEL; REAL-TIME QUANTITATIVE RT-PCR; REPORTER GENE; TARGET GENES; UP-REGULATION;

CELL MEMBRANES; CELL PROLIFERATION; DISEASES; GENE EXPRESSION; HISTOLOGY; PATIENT TREATMENT; PROTEINS; RNA; TISSUE;

CYTOLOGY;

ARGONAUTE 2 PROTEIN; CELL PROTEIN; ENDOPLASMIC RETICULUM GOLGI INTERMEDIATE COMPARTMENT PROTEIN 3; ENHANCED GREEN FLUORESCENT PROTEIN; MESSENGER RNA; MICRORNA; MICRORNA 490 3P; UNCLASSIFIED DRUG;

3' UNTRANSLATED REGION; ARTICLE; CANCER GROWTH; CANCER PATIENT; CANCER TISSUE; CELL INVASION; CELL MIGRATION; CELL PROLIFERATION; CELL STRAIN HEPG2; CONTROLLED STUDY; EPITHELIAL MESENCHYMAL TRANSITION; GENE FUNCTION; GENE OVEREXPRESSION; GENE SILENCING; GENETIC REGULATION; HUMAN; HUMAN CELL; HUMAN TISSUE; LIVER CARCINOGENESIS; LIVER CELL CARCINOMA; MOLECULAR INTERACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN TARGETING; REAL TIME POLYMERASE CHAIN REACTION; REPORTER GENE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; UPREGULATION;

ARGONAUTE PROTEINS; CARCINOMA, HEPATOCELLULAR; EPITHELIAL-MESENCHYMAL TRANSITION; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; LIVER NEOPLASMS; MALE; MEMBRANE PROTEINS; MICRORNAS; NEOPLASM PROTEINS; RNA, MESSENGER; RNA, NEOPLASM; UP-REGULATION;

EID: 84873636632     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.410506     Document Type: Article

References (48)

1. Forner, A., Llovet, J. M., and Bruix, J. (2012) Hepatocellular carcinoma. Lancet 379, 1245-1255
2. Waly Raphael, S., Yangde, Z., and Yuxiang, C. (2012) Hepatocellular carcinoma. Focus on different aspects of management. ISRN Oncol. 2012, 421673
3. Bosch, F. X., Ribes, J., Díaz, M., and Cléries, R. (2004) Primary liver cancer. Worldwide incidence and trends. Gastroenterology 127, S5-S16
4. Farazi, P. A., and DePinho, R. A. (2006) Hepatocellular carcinoma pathogenesis. From genes to environment. Nat Rev. Cancer 6, 674-687
5. Llovet, J. M., Ricci, S., Mazzaferro, V., Hilgard, P., Gane, E., Blanc, J. F., de Oliveira, A. C, Santoro, A., Raoul, J. L., Forner, A., Schwartz, M., Porta, C, Zeuzem, S., Bolondi, L., Greten, T. F., Galle, P. R., Seitz, J. F., Borbath, I., Háussinger, D., Giannaris, T., Shan, M., Moscovici, M., Voliotis, D., Bruix, J., and the SHARP Investigators Study Group (2008) Sorafenib in advanced hepatocellular carcinoma. N. Engl. J. Med. 359, 378-390
6. Thiery, J. P. (2002) Epithelial-mesenchymal transitions in tumour progression. Nat Rev. Cancer 2, 442-454
7. Saini, S., Majid, S., Yamamura, S., Tabatabai, L., Suh, S. O., Shahryari, V., Chen, Y., Deng, G., Tanaka, Y., and Dahiya, R. (2011) Regulatory role of mir-203 in prostate cancer progression and metastasis. Clin. Cancer Res. 17, 5287-5298
8. Toffanin, S., Hoshida, Y., Lachenmayer, A., Villanueva, A., Cabellos, L., Minguez, B., Savic, R., Ward, S. C., Thung, S., Chiang, D. Y., Alsinet, C, Tovar, V., Roayaie, S., Schwartz, M., Bruix, J., Waxman, S., Friedman, S. L., Golub, T., Mazzaferro, V., and Llovet, J. M. (2011) MicroRNA-based classification of hepatocellular carcinoma and oncogenic role of miR-517a. Gastroenterology 140, 1618-1628.e16
9. Bartel, D. P. (2004) MicroRNAs. Genomics, biogenesis, mechanism, and function. Cell 116, 281-297
10. Kim, V. N., Han, J., and Siomi, M. C. (2009) Biogenesis of small RNAs in animals. Nat Rev. Mol. Cell Biol. 10, 126-139
11. Lee, Y., Ahn, C, Han, J., Choi, H., Kim, J., Yim, J., Lee, J., Provost, P., Rådmark, O., Kim, S., and Kim, V. N. (2003) The nuclear RNase III Drosha initiates microRNA processing. Nature 425, 415-419
12. Lee, Y., Jeon, K., Lee, J. T., Kim, S., and Kim, V. N. (2002) MicroRNA maturation. Stepwise processing and subcellular localization. EMBOJ. 21, 4663-4670
13. Grishok, A., Pasquinelli, A. E., Conte, D., Li, N., Parrish, S., Ha, I., Baillie, D. L., Fire, A., Ruvkun, G., and Mello, C. C. (2001) Genes and mechanisms related to RNA interference regulate expression of the small temporal RNAs that control C. elegans developmental timing. Cell 106, 23-34
14. Djuranovic, S., Nahvi, A., and Green, R. (2011) A parsimonious model for gene regulation by miRNAs. Science 331, 550-553
15. Lim, L. P., Lau, N. C, Garrett-Engele, P., Grimson, A., Schelter, J. M., Castle, J., Bartel, D. P., Linsley, P. S., and Johnson, J. M. (2005) Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs. Nature 433, 769-773
16. Tsai, N. P., Lin, Y. L., and Wei, L. N. (2009) MicroRNA mir-346 targets the 5'-untranslated region of receptor-interacting protein 140 (RIP140) mRNA and up-regulates its protein expression. Biochem. J. 424, 411-418
17. Kang, H. W., Wang, F., Wei, Q., Zhao, Y. F., Liu, M., Li, X., and Tang, H. (2012) miR-20a promotes migration and invasion by regulating TNKS2 in human cervical cancer cells. FEBS Lett. 586, 897-904
18. Friedman, R. C, Farh, K. K., Burge, C. B., and Bartel, D. P. (2009) Most mammalian mRNAs are conserved targets of microRNAs. Genome Res. 19, 92-105
19. Ambros, V. (2004) The functions of animal microRNAs. Nature 431, 350-355
20. Sreekumar, R., Sayan, B. S, Mirnezami, A. H, and Sayan, A. E. (2011) MicroRNA control of invasion and metastasis pathways. Front. Genet. 2, 58
21. Dong, P., Kaneuchi, M., Watari, H, Hamada, J., Sudo, S., Ju, J., and Sakuragi, N. (2011) MicroRNA-194 inhibits epithelial to mesenchymal transition of endometrial cancer cells by targeting oncogene BMI-1. Mol. Cancer 10, 99
22. Zhang, Y., Yan, L. X., Wu, Q. N., Du, Z. M., Chen, J., Liao, D. Z., Huang, M. Y., Hou, J. H, Wu, Q. L., Zeng, M. S., Huang, W. L., Zeng, Y. X., and Shao, J. Y. (2011) miR-125b is methylated and functions as a tumor suppressor by regulating the ETS1 proto-oncogene in human invasive breast cancer. Cancer Res. 71, 3552-3562
23. Gaziel-Sovran, A., Segura, M. F., Di Micco, R., Collins, M. K., Hanniford, D., Vega-Saenz de Miera, E., Rakus, J. F., Dankert, J. F., Shang, S., Kerbel, R. S., Bhardwaj, N., Shao, Y., Darvishian, F., Zavadil, J., Erlebacher, A., Mahal, L. K., Osman, I., and Hernando, E. (2011) miR-30b/30d regulation of GalNAc transferases enhances invasion and immunosuppression during metastasis. Cancer Cell 20, 104-118
24. Buurman, R., Gürlevik, E., Schäffer, V., Eilers, M., Sandbothe, M., Kreipe, H., Wilkens, L., Schlegelberger, B., Kühnel, F., and Skawran, B. (2012) Histone deacetylases activate hepatocyte growth factor signaling by repressing microRNA-449 in hepatocellular carcinoma cells. Gastroenterol-ogy 143, 811-820.e1-e15
25. Shih, T. C., Tien, Y. J., Wen, C. J., Yeh, T. S., Yu, M. C., Huang, C. H., Lee, Y. S., Yen, T. C., and Hsieh, S. Y. (2012) MicroRNA-214 downregulation contributes totumor angiogenesisbyinducing secretionof the hepatoma-derived growth factor in human hepatoma. J. Hepatol. 57, 584-591
26. Callegari, E., Elamin, B. K., Giannone, F., Milazzo, M., Altavilla, G., For-nari, F., Giacomelli, L., D'Abundo, L., Ferracin, M., Bassi, C., Zagatti, B., Corrà, F., Miotto, E., Lupini, L., Bolondi, L., Gramantieri, L., Croce, C. M., Sabbioni, S., and Negrini, M. (2012) Liver tumorigenicity promoted by microRNA-221 in a mouse transgenic model. Hepatology 56, 1025-1033
27. Alpini, G., Glaser, S. S., Zhang, J. P., Francis, H., Han, Y., Gong, J., Stokes, A., Francis, T., Hughart, N., Hubble, L., Zhuang, S.M., and Meng, F. (2011) Regulation of placenta growth factor by microRNA-125b in hepatocellu-lar cancer. J. Hepatol. 55, 1339-1345
28. Hamfjord, J., Stangeland, A. M., Hughes, T., Skrede, M. L., Tveit, K. M., Ikdahl, T., and Kure, E. H. (2012) Differential expression of miRNAs in colorectal cancer. Comparisonofpaired tumor tissue and adjacent normal mucosa using high-throughput sequencing. PLoS One 7, e34150
29. Nakatani, F., Ferracin, M., Manara, M. C., Ventura, S., Del Monaco, V., Ferrari, S., Alberghini, M., Grilli, A., Knuutila, S., Schaefer, K. L., Mattia, G., Negrini, M., Picci, P., Serra, M., and Scotlandi, K. (2012) miR-34a predicts survival of Ewing's sarcoma patients and directly influences cell chemo-sensitivity and malignancy. J. Pathol. 226, 796-805
30. Heo, I., and Kim, V. N. (2009) Regulating the regulators. Posttranslational modifications of RNA silencing factors. Cell 139, 28-31
31. Trabucchi, M., Briata, P., Garcia-Mayoral, M., Haase, A. D., Filipowicz, W., Ramos, A., Gherzi, R., and Rosenfeld, M. G. (2009) The RNA-binding protein KSRP promotes the biogenesis of a subset of microRNAs. Nature 459, 1010-1014
32. Liang, L., Wong, C. M., Ying, Q., Fan, D. N., Huang, S., Ding, J., Yao, J., Yan, M., Li, J., Yao, M., Ng, I. O., and He, X. (2010) MicroRNA-125b suppresse-sed human liver cancer cell proliferation and metastasis by directly targeting oncogene LIN28B2. Hepatology 52, 1731-1740
33. Liu, L. H., Li, H., Li, J. P., Zhong, H., Zhang, H. C., Chen, J., and Xiao, T. (2011) miR-125b suppresses the proliferation and migration of osteosar-coma cells through down-regulation of STAT3. Biochem. Biophys. Res. Commun. 416, 31-38
34. Jiang, F., Liu, T., He, Y., Yan, Q., Chen, X., Wang, H., and Wan, X. (2011) MiR-125b promotes proliferation and migration of type II endometrial carcinoma cells through targeting TP53INP1 tumor suppressor in vitro and in vivo. BMC Cancer 11, 425
35. Tang, F., Zhang, R., He, Y., Zou, M., Guo, L., and Xi, T. (2012) MicroRNA-125b induces metastasisbytargeting STARD13inMCF-7and MDA-MB-231 breast cancer cells. PLoS One 7, e35435
36. 1/S transition by targeting p21Cip1/Waf1 in hepatocellular carcinoma. Carcinogenesis 32, 1641-1647
37. Shi, W., Gerster, K., Alajez, N. M., Tsang, J., Waldron, L., Pintilie, M., Hui, A. B., Sykes, J., P'ng, C., Miller, N., McCready, D., Fyles, A., and Liu, F. F. (2011) MicroRNA-301 mediates proliferation and invasion in human breast cancer. Cancer Res. 71, 2926-2937
38. Gregory, P. A., Bracken, C. P., Bert, A. G., and Goodall, G. J. (2008) Mi-croRNAs as regulators of epithelial-mesenchymal transition. Cell Cycle 7, 3112-3118
39. Gregory, P. A., Bert, A. G., Paterson, E. L., Barry, S. C, Tsykin, A., Farshid, G., Vadas, M. A., Khew-Goodall, Y., and Goodall, G. J. (2008) ThemiR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1. Nat. Cell Biol. 10, 593-601
40. Satelli, A., and Li, S. (2011) Vimentin in cancer and its potential as a molecular target for cancer therapy. Cell. Mol. Life Sci. 68, 3033-3046
41. Sudo, T., Iwaya, T., Nishida, N, Sawada, G., Takahashi, Y., Ishibashi, M., Shibata, K., Fujita, H., Shirouzu, K., Mori, M., and Mimori, K. (2012) Ann. Surg. Oncol, DOI: 10.1245/s10434-012-2418-z
42. Kroepil, F., Fluegen, G., Totikov, Z., Baldus, S. E., Vay, C., Schauer, M., Topp, S.A., Esch, J.S., Knoefel, W. T., and Stoecklein, N. H. (2012) Down-regulation of CDH1 is associated with expression of SNAI1 in colorectal adenomas. PLoS One 7, e46665
43. Li, J., and Zhou, B. P. (2011) Activation of β-catenin and Akt pathways by Twist are critical for the maintenance of EMT associated cancer stem cell-like characters. BMC cancer 11, 49
44. Ørom, U. A., Nielsen, F. C., and Lund, A. H. (2008) MicroRNA-10a binds the 5'UTR of ribosomal protein mRNAs and enhances their translation. Mol. Cell 30, 460-471
45. Shimakami, T., Yamane, D., Jangra, R. K., Kempf, B. J., Spaniel, C., Barton, D. J., and Lemon, S. M. (2012) Stabilization of hepatitis C virus RNA by an Ago2-miR-122 complex. Proc. Natl. Acad. Sci. U.S.A. 109, 941-946
46. Huang, V., Place, R. F., Portnoy, V., Wang, J., Qi, Z., Jia, Z., Yu, A., Shuman, M., Yu, J., and Li, L. C. (2012) Upregulation of cyclin B1 by miRNA and its implications in cancer. Nucleic Acids Res. 40, 1695-1707
47. Vasudevan, S., and Steitz, J. A. (2007) AU-rich-element- mediatedupregulation of translation by FXR1 and Argonaute 2. Cell 128, 1105-1118
48. Nishikawa, M., Kira, Y., Yabunaka, Y., and Inoue, M. (2007) Identification and characterization of endoplasmic reticulum-associated protein, ERp43. Gene 386, 42-51