-
1
-
-
84860390334
-
Predictive biomarkers: A paradigm shift towards personalized cancer medicine
-
La Thangue NB, Kerr DJ: Predictive biomarkers: A paradigm shift towards personalized cancer medicine. Nat Rev Clin Oncol 8:587-596, 2011
-
(2011)
Nat Rev Clin Oncol
, vol.8
, pp. 587-596
-
-
La Thangue, N.B.1
Kerr, D.J.2
-
2
-
-
77951778977
-
Personalized medicine in oncology: The future is now
-
Schilsky RL: Personalized medicine in oncology: The future is now. Nat Rev Drug Discov 9:363-366, 2010
-
(2010)
Nat Rev Drug Discov
, vol.9
, pp. 363-366
-
-
Schilsky, R.L.1
-
3
-
-
55349099142
-
A personalized approach to cancer treatment: How biomarkers can help
-
Duffy MJ, Crown J: A personalized approach to cancer treatment: How biomarkers can help. Clin Chem 54:1770-1779, 2008
-
(2008)
Clin Chem
, vol.54
, pp. 1770-1779
-
-
Duffy, M.J.1
Crown, J.2
-
4
-
-
84863889174
-
Under-representation of older adults in cancer registration trials: Known problem, little progress
-
Scher KS, Hurria A: Under-representation of older adults in cancer registration trials: Known problem, little progress. J Clin Oncol 30:2036-2038, 2012
-
(2012)
J Clin Oncol
, vol.30
, pp. 2036-2038
-
-
Scher, K.S.1
Hurria, A.2
-
5
-
-
62849096370
-
Adjuvant imatinib mesylate after resection of localised, primary gastrointestinal stromal tumour: A randomised, double-blind, placebo-controlled trial
-
Dematteo RP, Ballman KV, Antonescu CR, et al: Adjuvant imatinib mesylate after resection of localised, primary gastrointestinal stromal tumour: A randomised, double-blind, placebo-controlled trial. Lancet 373:1097-1104, 2009
-
(2009)
Lancet
, vol.373
, pp. 1097-1104
-
-
Dematteo, R.P.1
Ballman, K.V.2
Antonescu, C.R.3
-
6
-
-
84885386346
-
Imatinib failure-free survival (IFS) in patients with localized gastrointestinal stromal tumors (GIST) treated with adjuvant imatinib (IM): The EORTC/AGITG/FSG/GEIS/ISG randomized controlled phase III trial
-
(abstr 10500)
-
Casali PG, Le Cesne A, Velasco AP, et al: Imatinib failure-free survival (IFS) in patients with localized gastrointestinal stromal tumors (GIST) treated with adjuvant imatinib (IM): The EORTC/AGITG/FSG/GEIS/ISG randomized controlled phase III trial. J Clin Oncol 31, 2013 (suppl 15s; abstr 10500)
-
(2013)
J Clin Oncol
, vol.31
, Issue.SUPPL. 15S
-
-
Casali, P.G.1
Le Cesne, A.2
Velasco, A.P.3
-
7
-
-
84859187987
-
One vs three years of adjuvant imatinib for operable gastrointestinal stromal tumor: A randomized trial
-
Joensuu H, Eriksson M, Sundby Hall K, et al: One vs three years of adjuvant imatinib for operable gastrointestinal stromal tumor: A randomized trial. JAMA 307:1265-1272, 2012
-
(2012)
JAMA
, vol.307
, pp. 1265-1272
-
-
Joensuu, H.1
Eriksson, M.2
Sundby Hall, K.3
-
8
-
-
69949162760
-
Gefitinib or carboplatin-paclitaxel in pulmonary adenocarcinoma
-
Mok TS, Wu YL, Thongprasert S, et al: Gefitinib or carboplatin-paclitaxel in pulmonary adenocarcinoma. N Engl J Med 361:947-957, 2009
-
(2009)
N Engl J Med
, vol.361
, pp. 947-957
-
-
Mok, T.S.1
Wu, Y.L.2
Thongprasert, S.3
-
9
-
-
52049096854
-
Gefitinib versus vinorelbine in chemotherapy-naive elderly patients with advanced non-small-cell lung cancer (INVITE): A randomized, phase II study
-
Crinò L, Cappuzzo F, Zatloukal P, et al: Gefitinib versus vinorelbine in chemotherapy-naive elderly patients with advanced non-small-cell lung cancer (INVITE): A randomized, phase II study. J Clin Oncol 26:4253-4260, 2008
-
(2008)
J Clin Oncol
, vol.26
, pp. 4253-4260
-
-
Crinò, L.1
Cappuzzo, F.2
Zatloukal, P.3
-
10
-
-
22044445517
-
Erlotinib in previously treated non-small-cell lung cancer
-
DOI 10.1056/NEJMoa050753
-
Shepherd FA, Rodrigues Pereira J, Ciuleanu T, et al: Erlotinib in previously treated non-small-cell lung cancer. N Engl J Med 353:123-132, 2005 (Pubitemid 41058344)
-
(2005)
New England Journal of Medicine
, vol.353
, Issue.2
, pp. 123-132
-
-
Shepherd, F.A.1
Pereira, J.R.2
Ciuleanu, T.3
Eng, H.T.4
Hirsh, V.5
Thongprasert, S.6
Campos, D.7
Maoleekoonpiroj, S.8
Smylie, M.9
Martins, R.10
Van Kooten, M.11
Dediu, M.12
Findlay, B.13
Tu, D.14
Johnston, D.15
Bezjak, A.16
Clark, G.17
Santabarbara, P.18
Seymour, L.19
-
11
-
-
84857502654
-
Erlotinib versus standard chemotherapy as first-line treatment for European patients with advanced EGFR mutation-positive non-small-cell lung cancer (EURTAC): A multicentre, open-label, randomised phase 3 trial
-
Rosell R, Carcereny E, Gervais R, et al: Erlotinib versus standard chemotherapy as first-line treatment for European patients with advanced EGFR mutation-positive non-small-cell lung cancer (EURTAC): A multicentre, open-label, randomised phase 3 trial. Lancet Oncol 13:239-246, 2012
-
(2012)
Lancet Oncol
, vol.13
, pp. 239-246
-
-
Rosell, R.1
Carcereny, E.2
Gervais, R.3
-
12
-
-
47949116252
-
Sorafenib in advanced hepatocellular carcinoma
-
Llovet JM, Ricci S, Mazzaferro V, et al: Sorafenib in advanced hepatocellular carcinoma. N Engl J Med 359:378-390, 2008
-
(2008)
N Engl J Med
, vol.359
, pp. 378-390
-
-
Llovet, J.M.1
Ricci, S.2
Mazzaferro, V.3
-
13
-
-
84863078767
-
Everolimus in postmenopausal hormone-receptorpositive advanced breast cancer
-
Baselga J, Campone M, Piccart M, et al: Everolimus in postmenopausal hormone-receptorpositive advanced breast cancer. N Engl J Med 366:520-529, 2012
-
(2012)
N Engl J Med
, vol.366
, pp. 520-529
-
-
Baselga, J.1
Campone, M.2
Piccart, M.3
-
14
-
-
26844503270
-
Trastuzumab after adjuvant chemotherapy in HER2-positive breast cancer
-
DOI 10.1056/NEJMoa052306
-
Piccart-Gebhart MJ, Procter M, Leyland-Jones B, et al: Trastuzumab after adjuvant chemotherapy in HER2-positive breast cancer. N Engl J Med 353:1659-1672, 2005 (Pubitemid 41464705)
-
(2005)
New England Journal of Medicine
, vol.353
, Issue.16
, pp. 1659-1672
-
-
Piccart-Gebhart, M.J.1
Procter, M.2
Leyland-Jones, B.3
Goldhirsch, A.4
Untch, M.5
Smith, I.6
Gianni, L.7
Baselga, J.8
Bell, R.9
Jackisch, C.10
Cameron, D.11
Dowsett, M.12
Barrios, C.H.13
Steger, G.14
Huang, C.-S.15
Andersson, M.16
Inbar, M.17
Lichinitser, M.18
Lang, I.19
Nitz, U.20
Iwata, H.21
Thomssen, C.22
Lohrisch, C.23
Suter, T.M.24
Ruschoff, J.25
Suto, T.26
Greatorex, V.27
Ward, C.28
Straehle, C.29
McFadden, E.30
Dolci, M.S.31
Gelber, R.D.32
more..
-
15
-
-
84862914692
-
Pertuzumab plus trastuzumab plus docetaxel for metastatic breast cancer
-
Baselga J, Cortés J, Kim SB, et al: Pertuzumab plus trastuzumab plus docetaxel for metastatic breast cancer. N Engl J Med 366:109-119, 2012
-
(2012)
N Engl J Med
, vol.366
, pp. 109-119
-
-
Baselga, J.1
Cortés, J.2
Kim, S.B.3
-
16
-
-
84868520609
-
Trastuzumab emtansine for HER2-positive advanced breast cancer
-
Verma S, Miles D, Gianni L, et al: Trastuzumab emtansine for HER2-positive advanced breast cancer. N Engl J Med 367:1783-1791, 2012
-
(2012)
N Engl J Med
, vol.367
, pp. 1783-1791
-
-
Verma, S.1
Miles, D.2
Gianni, L.3
-
17
-
-
79959795786
-
Improved survival with vemurafenib in melanoma with BRAF V600E mutation
-
Chapman PB, Hauschild A, Robert C, et al: Improved survival with vemurafenib in melanoma with BRAF V600E mutation. N Engl J Med 364: 2507-2516, 2011
-
(2011)
N Engl J Med
, vol.364
, pp. 2507-2516
-
-
Chapman, P.B.1
Hauschild, A.2
Robert, C.3
-
18
-
-
84864285704
-
Dabrafenib in BRAF-mutated metastatic melanoma: A multicentre, open-label, phase 3 randomised controlled trial
-
Hauschild A, Grob JJ, Demidov LV, et al: Dabrafenib in BRAF-mutated metastatic melanoma: A multicentre, open-label, phase 3 randomised controlled trial. Lancet 380:358-365, 2012
-
(2012)
Lancet
, vol.380
, pp. 358-365
-
-
Hauschild, A.1
Grob, J.J.2
Demidov, L.V.3
-
19
-
-
77954801079
-
Improved survival with ipilimumab in patients with metastatic melanoma
-
Hodi FS, O'Day SJ, McDermott DF, et al: Improved survival with ipilimumab in patients with metastatic melanoma. N Engl J Med 363:711-723, 2010
-
(2010)
N Engl J Med
, vol.363
, pp. 711-723
-
-
Hodi, F.S.1
O'Day, S.J.2
McDermott, D.F.3
-
20
-
-
33846181370
-
Sunitinib versus interferon alfa in metastatic renal-cell carcinoma
-
DOI 10.1056/NEJMoa065044
-
Motzer RJ, Hutson TE, Tomczak P, et al: Sunitinib versus interferon alfa in metastatic renalcell carcinoma. N Engl J Med 356:115-124, 2007 (Pubitemid 46089672)
-
(2007)
New England Journal of Medicine
, vol.356
, Issue.2
, pp. 115-124
-
-
Motzer, R.J.1
Hutson, T.E.2
Tomczak, P.3
Michaelson, D.4
Bukowski, R.M.5
Rixe, O.6
Oudard, S.7
Negrier, S.8
Szczylik, C.9
Kim, S.T.10
Chen, I.11
Bycott, P.W.12
Baum, C.M.13
Figlin, R.A.14
-
21
-
-
77949890945
-
Pazopanib in locally advanced or metastatic renal cell carcinoma: Results of a randomized phase III trial
-
Sternberg CN, Davis ID, Mardiak J, et al: Pazopanib in locally advanced or metastatic renal cell carcinoma: Results of a randomized phase III trial. J Clin Oncol 28:1061-1068, 2010
-
(2010)
J Clin Oncol
, vol.28
, pp. 1061-1068
-
-
Sternberg, C.N.1
Davis, I.D.2
Mardiak, J.3
-
22
-
-
33846148701
-
Sorafenib in advanced clear-cell renal-cell carcinoma
-
DOI 10.1056/NEJMoa060655
-
Escudier B, Eisen T, Stadler WM, et al: Sorafenib in advanced clear-cell renal-cell carcinoma. N Engl J Med 356:125-134, 2007 (Pubitemid 46089673)
-
(2007)
New England Journal of Medicine
, vol.356
, Issue.2
, pp. 125-134
-
-
Escudier, B.1
Eisen, T.2
Stadler, W.M.3
Szczylik, C.4
Oudard, S.5
Siebels, M.6
Negrier, S.7
Chevreau, C.8
Solska, E.9
Desai, A.A.10
Rolland, F.11
Demkow, T.12
Hutson, T.E.13
Gore, M.14
Freeman, S.15
Schwartz, B.16
Shan, M.17
Simantov, R.18
Bukowski, R.M.19
-
23
-
-
82755183572
-
Comparative effectiveness of axitinib versus sorafenib in advanced renal cell carcinoma (AXIS): A randomised phase 3 trial
-
Rini BI, Escudier B, Tomczak P, et al: Comparative effectiveness of axitinib versus sorafenib in advanced renal cell carcinoma (AXIS): A randomised phase 3 trial. Lancet 378:1931-1939, 2011
-
(2011)
Lancet
, vol.378
, pp. 1931-1939
-
-
Rini, B.I.1
Escudier, B.2
Tomczak, P.3
-
24
-
-
63849088630
-
Cetuximab and chemotherapy as initial treatment for metastatic colorectal cancer
-
Van Cutsem E, Köhne CH, Hitre E, et al: Cetuximab and chemotherapy as initial treatment for metastatic colorectal cancer. N Engl J Med 360:1408-1417, 2009
-
(2009)
N Engl J Med
, vol.360
, pp. 1408-1417
-
-
Van Cutsem, E.1
Köhne, C.H.2
Hitre, E.3
-
25
-
-
78149250536
-
Randomized, phase III trial of panitumumab with infusional fluorouracil, leucovorin, and oxaliplatin (FOLFOX4) versus FOLFOX4 alone as first-line treatment in patients with previously untreated metastatic colorectal cancer: The PRIME study
-
Douillard JY, Siena S, Cassidy J, et al: Randomized, phase III trial of panitumumab with infusional fluorouracil, leucovorin, and oxaliplatin (FOLFOX4) versus FOLFOX4 alone as first-line treatment in patients with previously untreated metastatic colorectal cancer: The PRIME study. J Clin Oncol 28:4697-4705, 2010
-
(2010)
J Clin Oncol
, vol.28
, pp. 4697-4705
-
-
Douillard, J.Y.1
Siena, S.2
Cassidy, J.3
-
26
-
-
77956262693
-
Trastuzumab in combination with chemotherapy versus chemotherapy alone for treatment of HER2-positive advanced gastric or gastro-oesophageal junction cancer (ToGA): A phase 3, open-label, randomised controlled trial
-
Bang YJ, Van Cutsem E, Feyereislova A, et al: Trastuzumab in combination with chemotherapy versus chemotherapy alone for treatment of HER2-positive advanced gastric or gastro-oesophageal junction cancer (ToGA): A phase 3, open-label, randomised controlled trial. Lancet 376:687-697, 2010
-
(2010)
Lancet
, vol.376
, pp. 687-697
-
-
Bang, Y.J.1
Van Cutsem, E.2
Feyereislova, A.3
-
27
-
-
15644363454
-
Gain-of-function mutations of c-kit in human gastrointestinal stromal tumors
-
DOI 10.1126/science.279.5350.577
-
Hirota S, Isozaki K, Moriyama Y, et al: Gain-offunction mutations of c-kit in human gastrointestinal stromal tumors. Science 279:577-580, 1998 (Pubitemid 28067289)
-
(1998)
Science
, vol.279
, Issue.5350
, pp. 577-580
-
-
Hirota, S.1
Isozaki, K.2
Moriyama, Y.3
Hashimoto, K.4
Nishida, T.5
Ishiguro, S.6
Kawano, K.7
Hanada, M.8
Kurata, A.9
Takeda, M.10
Tunio, G.M.11
Matsuzawa, Y.12
Kanakura, Y.13
Shinomura, Y.14
Kitamura, Y.15
-
28
-
-
0242670019
-
PDGFRA activating mutations in gastrointestinal stromal tumors
-
DOI 10.1126/science.1079666
-
Heinrich MC, Corless CL, Duensing A, et al: PDGFRA activating mutations in gastrointestinal stromal tumors. Science 299:708-710, 2003 (Pubitemid 36159485)
-
(2003)
Science
, vol.299
, Issue.5607
, pp. 708-710
-
-
Heinrich, M.C.1
Corless, C.L.2
Duensing, A.3
McGreevey, L.4
Chen, C.-J.5
Joseph, N.6
Singer, S.7
Griffith, D.J.8
Haley, A.9
Town, A.10
Demetri, G.D.11
Fletcher, C.D.M.12
Fletcher, J.A.13
-
29
-
-
33846436108
-
Cancer statistics, trends, and multiple primary cancer analyses from the surveillance, epidemiology, and end results (SEER) program
-
DOI 10.1634/theoncologist.12-1-20
-
Hayat MJ, Howlader N, Reichman ME, et al: Cancer statistics, trends, and multiple primary cancer analyses from the Surveillance, Epidemiology, and End Results (SEER) Program. Oncologist 12:20-37, 2007 (Pubitemid 46143500)
-
(2007)
Oncologist
, vol.12
, Issue.1
, pp. 20-37
-
-
Hayat, M.J.1
Howlader, N.2
Reichman, M.E.3
Edwards, B.K.4
-
30
-
-
79957492069
-
American Society of Clinical Oncology provisional clinical opinion: Epidermal growth factor receptor (EGFR) mutation testing for patients with advanced non-small-cell lung cancer considering first-line EGFR tyrosine kinase inhibitor therapy
-
Keedy VL, Temin S, Somerfield MR, et al: American Society of Clinical Oncology provisional clinical opinion: Epidermal growth factor receptor (EGFR) mutation testing for patients with advanced non-small-cell lung cancer considering first-line EGFR tyrosine kinase inhibitor therapy. J Clin Oncol 29:2121-2127, 2011
-
(2011)
J Clin Oncol
, vol.29
, pp. 2121-2127
-
-
Keedy, V.L.1
Temin, S.2
Somerfield, M.R.3
-
31
-
-
84866597083
-
Metastatic non-small-cell lung cancer (NSCLC): ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up
-
Peters S, Adjei AA, Gridelli C, et al: Metastatic non-small-cell lung cancer (NSCLC): ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up. Ann Oncol 23:vii56-vii64, 2012
-
(2012)
Ann Oncol
, vol.23
-
-
Peters, S.1
Adjei, A.A.2
Gridelli, C.3
-
32
-
-
83755207387
-
Incorporation of crizotinib into the NCCN guidelines
-
Riely GJ, Chaft JE, Ladanyi M, et al: Incorporation of crizotinib into the NCCN guidelines. J Natl Compr Canc Netw 9:1328-1330, 2011
-
(2011)
J Natl Compr Canc Netw
, vol.9
, pp. 1328-1330
-
-
Riely, G.J.1
Chaft, J.E.2
Ladanyi, M.3
-
33
-
-
44249121733
-
Erlotinib for advanced non-small-cell lung cancer in the elderly: An analysis of the National Cancer Institute of Canada Clinical Trials Group Study BR.21
-
Wheatley-Price P, Ding K, Seymour L, et al: Erlotinib for advanced non-small-cell lung cancer in the elderly: An analysis of the National Cancer Institute of Canada Clinical Trials Group Study BR.21. J Clin Oncol 26:2350-2357, 2008
-
(2008)
J Clin Oncol
, vol.26
, pp. 2350-2357
-
-
Wheatley-Price, P.1
Ding, K.2
Seymour, L.3
-
34
-
-
33947504732
-
Phase II clinical trial of chemotherapy-naive patients ≥ 70 years of age treated with erlotinib for advanced non-small-cell lung cancer
-
DOI 10.1200/JCO.2006.07.5754
-
Jackman DM, Yeap BY, Lindeman NI, et al: Phase II clinical trial of chemotherapy-naive patients > or = 70 years of age treated with erlotinib for advanced non-small-cell lung cancer. J Clin Oncol 25:760-766, 2007 (Pubitemid 350002874)
-
(2007)
Journal of Clinical Oncology
, vol.25
, Issue.7
, pp. 760-766
-
-
Jackman, D.M.1
Yeap, B.Y.2
Lindeman, N.I.3
Fidias, P.4
Rabin, M.S.5
Temel, J.6
Skarin, A.T.7
Meyerson, M.8
Holmes, A.J.9
Borras, A.M.10
Freidlin, B.11
Ostler, P.A.12
Lucca, J.13
Lynch, T.J.14
Johnson, B.E.15
Janne, P.A.16
-
35
-
-
84866934606
-
Activity and safety of crizotinib in patients with ALK-positive non-small-cell lung cancer: Updated results from a phase 1 study
-
Camidge DR, Bang YJ, Kwak EL, et al: Activity and safety of crizotinib in patients with ALK-positive non-small-cell lung cancer: Updated results from a phase 1 study. Lancet Oncol 13:1011-1019, 2012
-
(2012)
Lancet Oncol
, vol.13
, pp. 1011-1019
-
-
Camidge, D.R.1
Bang, Y.J.2
Kwak, E.L.3
-
36
-
-
84879071011
-
Crizotinib versus chemotherapy in advanced ALK-positive lung cancer
-
Shaw AT, Kim DW, Nakagawa K, et al: Crizotinib versus chemotherapy in advanced ALK-positive lung cancer. N Engl J Med 368:2385-2394, 2013
-
(2013)
N Engl J Med
, vol.368
, pp. 2385-2394
-
-
Shaw, A.T.1
Kim, D.W.2
Nakagawa, K.3
-
37
-
-
84874002381
-
Sorafenib in elderly patients with advanced hepatocellular carcinoma: A case series
-
Montella L, Addeo R, Cennamo G, et al: Sorafenib in elderly patients with advanced hepatocellular carcinoma: A case series. Oncology 84:265-272, 2013
-
(2013)
Oncology
, vol.84
, pp. 265-272
-
-
Montella, L.1
Addeo, R.2
Cennamo, G.3
-
38
-
-
84878366889
-
Targeted therapy for HER2 positive breast cancer
-
Incorvati JA, Shah S, Mu Y, et al: Targeted therapy for HER2 positive breast cancer. J Hematol Oncol 6:38, 2013
-
(2013)
J Hematol Oncol
, vol.6
, pp. 38
-
-
Incorvati, J.A.1
Shah, S.2
Mu, Y.3
-
39
-
-
0035869407
-
Use of chemotherapy plus a monoclonal antibody against her2 for metastatic breast cancer that overexpresses HER2
-
DOI 10.1056/NEJM200103153441101
-
Slamon DJ, Leyland-Jones B, Shak S, et al: Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2. N Engl J Med 344:783-792, 2001 (Pubitemid 32222155)
-
(2001)
New England Journal of Medicine
, vol.344
, Issue.11
, pp. 783-792
-
-
Slamon, D.J.1
Leyland-Jones, B.2
Shak, S.3
Fuchs, H.4
Paton, V.5
Bajamonde, A.6
Fleming, T.7
Eiermann, W.8
Wolter, J.9
Pegram, M.10
Baselga, J.11
Norton, L.12
-
40
-
-
84892845082
-
Trastuzumab-related cardiotoxicity among older patients with breast cancer
-
Chavez-MacGregor M, Zhang N, Buchholz TA, et al: Trastuzumab-related cardiotoxicity among older patients with breast cancer. J Clin Oncol 31:4222-4228, 2013
-
(2013)
J Clin Oncol
, vol.31
, pp. 4222-4228
-
-
Chavez-Macgregor, M.1
Zhang, N.2
Buchholz, T.A.3
-
41
-
-
77957567061
-
Trastuzumab-induced cardiotoxicity: Clinical and prognostic implications of troponin I evaluation
-
Cardinale D, Colombo A, Torrisi R, et al: Trastuzumab-induced cardiotoxicity: Clinical and prognostic implications of troponin I evaluation. J Clin Oncol 28:3910-3916, 2010
-
(2010)
J Clin Oncol
, vol.28
, pp. 3910-3916
-
-
Cardinale, D.1
Colombo, A.2
Torrisi, R.3
-
42
-
-
80053539103
-
Adjuvant trastuzumab in HER2-positive breast cancer
-
Slamon D, Eiermann W, Robert N, et al: Adjuvant trastuzumab in HER2-positive breast cancer. N Engl J Med 365:1273-1283, 2011
-
(2011)
N Engl J Med
, vol.365
, pp. 1273-1283
-
-
Slamon, D.1
Eiermann, W.2
Robert, N.3
-
43
-
-
26844536978
-
Trastuzumab plus adjuvant chemotherapy for operable HER2-positive breast cancer
-
DOI 10.1056/NEJMoa052122
-
Romond EH, Perez EA, Bryant J, et al: Trastuzumab plus adjuvant chemotherapy for operable HER2-positive breast cancer. N Engl J Med 353: 1673-1684, 2005 (Pubitemid 41464706)
-
(2005)
New England Journal of Medicine
, vol.353
, Issue.16
, pp. 1673-1684
-
-
Romond, E.H.1
Perez, E.A.2
Bryant, J.3
Suman, V.J.4
Geyer Jr., C.E.5
Davidson, N.E.6
Tan-Chiu, E.7
Martino, S.8
Paik, S.9
Kaufman, P.A.10
Swain, S.M.11
Pisansky, T.M.12
Fehrenbacher, L.13
Kutteh, L.A.14
Vogel, V.G.15
Visscher, D.W.16
Yothers, G.17
Jenkins, R.B.18
Brown, A.M.19
Dakhil, S.R.20
Mamounas, E.P.21
Lingle, W.L.22
Klein, P.M.23
Ingle, J.N.24
Wolmark, N.25
more..
-
44
-
-
84859510543
-
Trastuzumab-related cardiotoxicity in the elderly: A role for cardiovascular risk factors
-
Serrano C, Cortés J, De Mattos-Arruda L, et al: Trastuzumab-related cardiotoxicity in the elderly: A role for cardiovascular risk factors. Ann Oncol 23:897-902, 2012
-
(2012)
Ann Oncol
, vol.23
, pp. 897-902
-
-
Serrano, C.1
Cortés, J.2
De Mattos-Arruda, L.3
-
45
-
-
84866407689
-
Safety of adjuvant trastuzumab for HER-2-overexpressing elderly breast cancer patients: A multicenter cohort study
-
Sawaki M, Mukai H, Tokudome N, et al: Safety of adjuvant trastuzumab for HER-2-overexpressing elderly breast cancer patients: A multicenter cohort study. Breast Cancer 19:253-258, 2012
-
(2012)
Breast Cancer
, vol.19
, pp. 253-258
-
-
Sawaki, M.1
Mukai, H.2
Tokudome, N.3
-
46
-
-
84871576393
-
Tolerability and activity of trastuzumab in elderly patients with HER2-overexpressing metastatic breast cancer
-
Zucchini G, Bernardi A, Martoni A, et al: Tolerability and activity of trastuzumab in elderly patients with HER2-overexpressing metastatic breast cancer. Ann Oncol 24:264-265, 2013
-
(2013)
Ann Oncol
, vol.24
, pp. 264-265
-
-
Zucchini, G.1
Bernardi, A.2
Martoni, A.3
-
47
-
-
84893055153
-
The risk of toxicities from trastuzumab, alone or in combination, in an elderly breast cancer population
-
Adamo V, Ricciardi GR, Adamo B, et al: The risk of toxicities from trastuzumab, alone or in combination, in an elderly breast cancer population. Oncology 86:16-21, 2014
-
(2014)
Oncology
, vol.86
, pp. 16-21
-
-
Adamo, V.1
Ricciardi, G.R.2
Adamo, B.3
-
48
-
-
84894648709
-
Risk of cardiovascular adverse events from trastuzumab (Herceptin(®) in elderly persons with breast cancer: A population-based study
-
Tsai HT, Isaacs C, Fu AZ, et al: Risk of cardiovascular adverse events from trastuzumab (Herceptin(®) in elderly persons with breast cancer: A population-based study. Breast Cancer Res Treat 144:163-170, 2014
-
(2014)
Breast Cancer Res Treat
, vol.144
, pp. 163-170
-
-
Tsai, H.T.1
Isaacs, C.2
Fu, A.Z.3
-
49
-
-
79952742189
-
Multicenter analysis of activity and safety of trastuzumab plus chemotherapy in advanced breast cancer in elderly women (≥ 70 years)
-
(abstr 1096)
-
Brunello A, Monfardini S, Crivellari D, et al: Multicenter analysis of activity and safety of trastuzumab plus chemotherapy in advanced breast cancer in elderly women (≥ 70 years). J Clin Oncol 26:65s, 2008 (suppl; abstr 1096)
-
(2008)
J Clin Oncol
, vol.26
, Issue.SUPPL.
-
-
Brunello, A.1
Monfardini, S.2
Crivellari, D.3
-
50
-
-
33748573134
-
Postmenopausal advanced breast cancer: Options for therapy after tamoxifen and aromatase inhibitors
-
DOI 10.1016/j.breast.2006.01.007, PII S0960977606000300
-
Dodwell D, Wardley A, Johnston S: Postmenopausal advanced breast cancer: Options for therapy after tamoxifen and aromatase inhibitors. Breast 15:584-594, 2006 (Pubitemid 44509773)
-
(2006)
Breast
, vol.15
, Issue.5
, pp. 584-594
-
-
Dodwell, D.1
Wardley, A.2
Johnston, S.3
-
51
-
-
84889008307
-
Safety and efficacy of everolimus with exemestane vs. Exemestane alone in elderly patients with HER2-negative, hormone receptor-positive breast cancer in BOLERO-2
-
Pritchard KI, Burris HA 3rd, Ito Y, et al: Safety and efficacy of everolimus with exemestane vs. exemestane alone in elderly patients with HER2-negative, hormone receptor-positive breast cancer in BOLERO-2. Clin Breast Cancer 13:421.e8-432.e8, 2013
-
(2013)
Clin Breast Cancer
, vol.13
-
-
Pritchard, K.I.1
Burris III, H.A.2
Ito, Y.3
-
52
-
-
84859140429
-
Management of elderly patients with breast cancer: Updated recommendations of the International Society of Geriatric Oncology (SIOG) and European Society of Breast Cancer Specialists (EUSOMA)
-
Biganzoli L, Wildiers H, Oakman C, et al: Management of elderly patients with breast cancer: Updated recommendations of the International Society of Geriatric Oncology (SIOG) and European Society of Breast Cancer Specialists (EUSOMA). Lancet Oncol 13:e148-e160, 2012
-
(2012)
Lancet Oncol
, vol.13
-
-
Biganzoli, L.1
Wildiers, H.2
Oakman, C.3
-
53
-
-
73149115341
-
Lapatinib combined with letrozole versus letrozole and placebo as first-line therapy for postmenopausal hormone receptor-positive metastatic breast cancer
-
Johnston S, Pippen J Jr, Pivot X, et al: Lapatinib combined with letrozole versus letrozole and placebo as first-line therapy for postmenopausal hormone receptor-positive metastatic breast cancer. J Clin Oncol 27:5538-5546, 2009
-
(2009)
J Clin Oncol
, vol.27
, pp. 5538-5546
-
-
Johnston, S.1
Pippen Jr., J.2
Pivot, X.3
-
54
-
-
73949105921
-
Trastuzumab plus anastrozole versus anastrozole alone for the treatment of postmenopausal women with human epidermal growth factor receptor 2-positive, hormone receptor-positive metastatic breast cancer: Results from the randomized phase III TAnDEM study
-
Kaufman B, Mackey JR, Clemens MR, et al: Trastuzumab plus anastrozole versus anastrozole alone for the treatment of postmenopausal women with human epidermal growth factor receptor 2-positive, hormone receptor-positive metastatic breast cancer: Results from the randomized phase III TAnDEM study. J Clin Oncol 27:5529-5537, 2009
-
(2009)
J Clin Oncol
, vol.27
, pp. 5529-5537
-
-
Kaufman, B.1
MacKey, J.R.2
Clemens, M.R.3
-
55
-
-
33845886440
-
Lapatinib plus capecitabine for HER2-positive advanced breast cancer
-
DOI 10.1056/NEJMoa064320
-
Geyer CE, Forster J, Lindquist D, et al: Lapatinib plus capecitabine for HER2-positive advanced breast cancer. N Engl J Med 355:2733-2743, 2006 (Pubitemid 46021510)
-
(2006)
New England Journal of Medicine
, vol.355
, Issue.26
, pp. 2733-2743
-
-
Geyer, C.E.1
Forster, J.2
Lindquist, D.3
Chan, S.4
Romieu, C.G.5
Pienkowski, T.6
Jagiello-Gruszfeld, A.7
Crown, J.8
Chan, A.9
Kaufman, B.10
Skarlos, D.11
Campone, M.12
Davidson, N.13
Berger, M.14
Oliva, C.15
Rubin, S.D.16
Stein, S.17
Cameron, D.18
-
57
-
-
53949101266
-
Pooled analysis of diarrhea events in patients with cancer treated with lapatinib
-
Crown JP, Burris HA 3rd, Boyle F, et al: Pooled analysis of diarrhea events in patients with cancer treated with lapatinib. Breast Cancer Res Treat 112:317-325, 2008
-
(2008)
Breast Cancer Res Treat
, vol.112
, pp. 317-325
-
-
Crown, J.P.1
Burris III, H.A.2
Boyle, F.3
-
58
-
-
27844567142
-
Distinct sets of genetic alterations in melanoma
-
DOI 10.1056/NEJMoa050092
-
Curtin JA, Fridlyand J, Kageshita T, et al: Distinct sets of genetic alterations in melanoma. N Engl J Med 353:2135-2147, 2005 (Pubitemid 41653105)
-
(2005)
New England Journal of Medicine
, vol.353
, Issue.20
, pp. 2135-2147
-
-
Curtin, J.A.1
Fridlyand, J.2
Kageshita, T.3
Patel, H.N.4
Busam, K.J.5
Kutzner, H.6
Cho, K.-H.7
Aiba, S.8
Brocker, E.-B.9
LeBoit, P.E.10
Pinkel, D.11
Bastian, B.C.12
-
59
-
-
28244492012
-
Analysis of the cellular mechanism of antitumor responses and autoimmunity in patients treated with CTLA-4 blockade
-
Maker AV, Attia P, Rosenberg SA: Analysis of the cellular mechanism of antitumor responses and autoimmunity in patients treated with CTLA-4 blockade. J Immunol 175:7746-7754, 2005 (Pubitemid 41713475)
-
(2005)
Journal of Immunology
, vol.175
, Issue.11
, pp. 7746-7754
-
-
Maker, A.V.1
Attia, P.2
Rosenberg, S.A.3
-
60
-
-
84876495508
-
Optimal management of renal cell carcinoma in the elderly: A review
-
Quivy A, Daste A, Harbaoui A, et al: Optimal management of renal cell carcinoma in the elderly: A review. Clin Interv Aging 8:433-442, 2013
-
(2013)
Clin Interv Aging
, vol.8
, pp. 433-442
-
-
Quivy, A.1
Daste, A.2
Harbaoui, A.3
-
61
-
-
84856858236
-
A pooled analysis of the efficacy and safety of sunitinib in elderly patients (pts) with metastatic renal cell carcinoma (mRCC)
-
(abstr 4604)
-
Huston TE, Bukowski RM, Rini BI, et al: A pooled analysis of the efficacy and safety of sunitinib in elderly patients (pts) with metastatic renal cell carcinoma (mRCC). J Clin Oncol 29:314s, 2011 (suppl; abstr 4604)
-
(2011)
J Clin Oncol
, vol.29
, Issue.SUPPL.
-
-
Huston, T.E.1
Bukowski, R.M.2
Rini, B.I.3
-
62
-
-
84871885792
-
Sunitinib as first-line therapy in elderly patients (age 70 and older) with metastatic renal cell cancer
-
(abstr 411)
-
De Giorgi U, Rihawi K, Lo Re G, et al: Sunitinib as first-line therapy in elderly patients (age 70 and older) with metastatic renal cell cancer. J Clin Oncol 30, 2012 (suppl; abstr 411)
-
(2012)
J Clin Oncol
, vol.30
, Issue.SUPPL.
-
-
De Giorgi, U.1
Rihawi, K.2
Lo Re, G.3
-
63
-
-
84882781441
-
Pazopanib versus sunitinib in metastatic renal-cell carcinoma
-
Motzer RJ, Hutson TE, Cella D, et al: Pazopanib versus sunitinib in metastatic renal-cell carcinoma. N Engl J Med 369:722-731, 2013
-
(2013)
N Engl J Med
, vol.369
, pp. 722-731
-
-
Motzer, R.J.1
Hutson, T.E.2
Cella, D.3
-
64
-
-
84906222820
-
Clinical benefit of sorafenib in the elderly with advanced renal cell carcinoma: Subgroup analysis of the Approaches in Renal Cell Cancer Global Evaluation Trial (TARGETS)
-
(abstr 446PD)
-
Eisen T, Oudard S, Szczylik C, et al: Clinical benefit of sorafenib in the elderly with advanced renal cell carcinoma: Subgroup analysis of the Approaches in Renal Cell Cancer Global Evaluation Trial (TARGETS). Ann Oncol 17, 2006 (suppl 9; abstr 446PD)
-
(2006)
Ann Oncol
, vol.17
, Issue.SUPPL. 9
-
-
Eisen, T.1
Oudard, S.2
Szczylik, C.3
-
65
-
-
84873566624
-
Sorafenib tolerability in elderly patients with advanced renal cell carcinoma: Results from a large pooled analysis
-
Procopio G, Bellmunt J, Dutcher J, et al: Sorafenib tolerability in elderly patients with advanced renal cell carcinoma: Results from a large pooled analysis. Br J Cancer 108:311-318, 2013
-
(2013)
Br J Cancer
, vol.108
, pp. 311-318
-
-
Procopio, G.1
Bellmunt, J.2
Dutcher, J.3
-
66
-
-
48649107474
-
Efficacy of everolimus in advanced renal cell carcinoma: A doubleblind, randomised, placebo-controlled phase III trial
-
Motzer RJ, Escudier B, Oudard S, et al: Efficacy of everolimus in advanced renal cell carcinoma: A doubleblind, randomised, placebo-controlled phase III trial. Lancet 372:449-456, 2008
-
(2008)
Lancet
, vol.372
, pp. 449-456
-
-
Motzer, R.J.1
Escudier, B.2
Oudard, S.3
-
67
-
-
84862777361
-
Efficacy and safety of everolimus in elderly patients with metastatic renal cell carcinoma: An exploratory analysis of the outcomes of elderly patients in the RECORD-1 Trial
-
Porta C, Calvo E, Climent MA, et al: Efficacy and safety of everolimus in elderly patients with metastatic renal cell carcinoma: An exploratory analysis of the outcomes of elderly patients in the RECORD-1 Trial. Eur Urol 61:826-833, 2012
-
(2012)
Eur Urol
, vol.61
, pp. 826-833
-
-
Porta, C.1
Calvo, E.2
Climent, M.A.3
-
68
-
-
34249779568
-
Temsirolimus, interferon alfa, or both for advanced renal-cell carcinoma
-
DOI 10.1056/NEJMoa066838
-
Hudes G, Carducci M, Tomczak P, et al: Temsirolimus, interferon alfa, or both for advanced renal-cell carcinoma. N Engl J Med 356:2271-2281, 2007 (Pubitemid 46849157)
-
(2007)
New England Journal of Medicine
, vol.356
, Issue.22
, pp. 2271-2281
-
-
Hudes, G.1
Carducci, M.2
Tomczak, P.3
Dutcher, J.4
Figlin, R.5
Kapoor, A.6
Staroslawska, E.7
Sosman, J.8
McDermott, D.9
Bodrogi, I.10
Kovacevic, Z.11
Lesovoy, V.12
Schmidt-Wolf, I.G.H.13
Barbarash, O.14
Gokmen, E.15
O'Toole, T.16
Lustgarten, S.17
Moore, L.18
Motzer, R.J.19
-
69
-
-
34547636060
-
Correlation of survival with tumor histology, age, and prognostic risk group for previously untreated patients with advanced renal cell carcinoma (adv RCC) receiving temsirolimus (TEMSR) or interferon-alpha (IFN)
-
(abstr 5033)
-
Dutcher JP, Szczylik C, Tannir N, et al: Correlation of survival with tumor histology, age, and prognostic risk group for previously untreated patients with advanced renal cell carcinoma (adv RCC) receiving temsirolimus (TEMSR) or interferon-alpha (IFN). J Clin Oncol 25:243s, 2007 (suppl; abstr 5033)
-
(2007)
J Clin Oncol
, vol.25
, Issue.SUPPL.
-
-
Dutcher, J.P.1
Szczylik, C.2
Tannir, N.3
-
70
-
-
84876974877
-
Axitinib versus sorafenib as second-line treatment for advanced renal cell carcinoma: Overall survival analysis and updated results from a randomised phase 3 trial
-
Motzer RJ, Escudier B, Tomczak P, et al: Axitinib versus sorafenib as second-line treatment for advanced renal cell carcinoma: Overall survival analysis and updated results from a randomised phase 3 trial. Lancet Oncol 14:552-562, 2013
-
(2013)
Lancet Oncol
, vol.14
, pp. 552-562
-
-
Motzer, R.J.1
Escudier, B.2
Tomczak, P.3
-
71
-
-
84883680951
-
Panitumumab-FOLFOX4 treatment and RAS mutations in colorectal cancer
-
Douillard JY, Oliner KS, Siena S, et al: Panitumumab-FOLFOX4 treatment and RAS mutations in colorectal cancer. N Engl J Med 369:1023-1034, 2013
-
(2013)
N Engl J Med
, vol.369
, pp. 1023-1034
-
-
Douillard, J.Y.1
Oliner, K.S.2
Siena, S.3
-
72
-
-
84897406141
-
Influence of comorbidity, age and performance status on treatment efficacy and safety of cetuximab plus irinotecan in irinotecan-refractory elderly patients with metastatic colorectal cancer
-
Jehn CF, Böning L, Kröning H, et al: Influence of comorbidity, age and performance status on treatment efficacy and safety of cetuximab plus irinotecan in irinotecan-refractory elderly patients with metastatic colorectal cancer. Eur J Cancer 50:1269-1275, 2014
-
(2014)
Eur J Cancer
, vol.50
, pp. 1269-1275
-
-
Jehn, C.F.1
Böning, L.2
Kröning, H.3
-
73
-
-
42649145667
-
Wildtype KRAS is required for panitumumab efficacy in patients with metastatic colorectal cancer
-
Amado RG, Wolf M, Peeters M, et al: Wildtype KRAS is required for panitumumab efficacy in patients with metastatic colorectal cancer. J Clin Oncol 26:1626-1634, 2008
-
(2008)
J Clin Oncol
, vol.26
, pp. 1626-1634
-
-
Amado, R.G.1
Wolf, M.2
Peeters, M.3
-
74
-
-
78149239651
-
Randomized phase III study of panitumumab with fluorouracil, leucovorin, and irinotecan (FOLFIRI) compared with FOLFIRI alone as second-line treatment in patients with metastatic colorectal cancer
-
Peeters M, Price TJ, Cervantes A, et al: Randomized phase III study of panitumumab with fluorouracil, leucovorin, and irinotecan (FOLFIRI) compared with FOLFIRI alone as second-line treatment in patients with metastatic colorectal cancer. J Clin Oncol 28:4706-4713, 2010
-
(2010)
J Clin Oncol
, vol.28
, pp. 4706-4713
-
-
Peeters, M.1
Price, T.J.2
Cervantes, A.3
-
75
-
-
43549126000
-
Chemotherapy in elderly patients with colorectal cancer
-
DOI 10.1634/theoncologist.2007-0043
-
Köhne CH, Folprecht G, Goldberg RM, et al: Chemotherapy in elderly patients with colorectal cancer. Oncologist 13:390-402, 2008 (Pubitemid 351679918)
-
(2008)
Oncologist
, vol.13
, Issue.4
, pp. 390-402
-
-
Kohne, C.-H.1
Folprecht, G.2
Goldberg, R.M.3
Mitry, E.4
Rougier, P.5
-
77
-
-
84884700039
-
Bevacizumab plus capecitabine versus capecitabine alone in elderly patients with previously untreated metastatic colorectal cancer (AVEX): An open-label, randomised phase 3 trial
-
Cunningham D, Lang I, Marcuello E, et al: Bevacizumab plus capecitabine versus capecitabine alone in elderly patients with previously untreated metastatic colorectal cancer (AVEX): An open-label, randomised phase 3 trial. Lancet Oncol 14:1077-1085, 2013
-
(2013)
Lancet Oncol
, vol.14
, pp. 1077-1085
-
-
Cunningham, D.1
Lang, I.2
Marcuello, E.3
-
78
-
-
78649978359
-
Safety of bevacizumab in patients with advanced cancer: A meta-analysis of randomized controlled trials
-
Geiger-Gritsch S, Stollenwerk B, Miksad R, et al: Safety of bevacizumab in patients with advanced cancer: A meta-analysis of randomized controlled trials. Oncologist 15:1179-1191, 2010
-
(2010)
Oncologist
, vol.15
, pp. 1179-1191
-
-
Geiger-Gritsch, S.1
Stollenwerk, B.2
Miksad, R.3
-
79
-
-
62949116808
-
Bevacizumab (BV) related adverse events among various age groups of elderly patients with advanced colorectal cancer
-
(abstr 14546)
-
Raman AK, Lombardo JC, Chandrasekhar R, et al: Bevacizumab (BV) related adverse events among various age groups of elderly patients with advanced colorectal cancer. J Clin Oncol 25:628s, 2007 (suppl; abstr 14546)
-
(2007)
J Clin Oncol
, vol.25
, Issue.SUPPL.
-
-
Raman, A.K.1
Lombardo, J.C.2
Chandrasekhar, R.3
-
80
-
-
77956072936
-
Clinical outcomes in elderly patients with metastatic colorectal cancer receiving bevacizumab and chemotherapy: Results from the BRiTE observational cohort study
-
Kozloff MF, Berlin J, Flynn PJ, et al: Clinical outcomes in elderly patients with metastatic colorectal cancer receiving bevacizumab and chemotherapy: Results from the BRiTE observational cohort study. Oncology 78:329-339, 2010
-
(2010)
Oncology
, vol.78
, pp. 329-339
-
-
Kozloff, M.F.1
Berlin, J.2
Flynn, P.J.3
-
81
-
-
79959426381
-
Vascular endothelial growth factor inhibitor-induced hypertension: Basics for primary care providers
-
Escalante CP, Zalpour A: Vascular endothelial growth factor inhibitor-induced hypertension: Basics for primary care providers. Cardiol Res Pract 2011: 816897, 2011
-
(2011)
Cardiol Res Pract
, vol.2011
, pp. 816897
-
-
Escalante, C.P.1
Zalpour, A.2
-
83
-
-
56649123212
-
Risk of venous thromboembolism with the angiogenesis inhibitor bevacizumab in cancer patients: A metaanalysis
-
Nalluri SR, Chu D, Keresztes R, et al: Risk of venous thromboembolism with the angiogenesis inhibitor bevacizumab in cancer patients: A metaanalysis. JAMA 300:2277-2285, 2008
-
(2008)
JAMA
, vol.300
, pp. 2277-2285
-
-
Nalluri, S.R.1
Chu, D.2
Keresztes, R.3
-
84
-
-
79955587689
-
Venous thromboembolic events with chemotherapy plus bevacizumab: A pooled analysis of patients in randomized phase II and III studies
-
Hurwitz HI, Saltz LB, Van Cutsem E, et al: Venous thromboembolic events with chemotherapy plus bevacizumab: A pooled analysis of patients in randomized phase II and III studies. J Clin Oncol 29:1757-1764, 2011
-
(2011)
J Clin Oncol
, vol.29
, pp. 1757-1764
-
-
Hurwitz, H.I.1
Saltz, L.B.2
Van Cutsem, E.3
-
85
-
-
84891447681
-
Angiogenic inhibitors for older patients with advanced colorectal cancer: Does the age hold the stage?
-
Aprile G, Fontanella C, Lutrino ES, et al: Angiogenic inhibitors for older patients with advanced colorectal cancer: Does the age hold the stage? World J Gastroenterol 19:2131-2140, 2013
-
(2013)
World J Gastroenterol
, vol.19
, pp. 2131-2140
-
-
Aprile, G.1
Fontanella, C.2
Lutrino, E.S.3
-
86
-
-
79960980997
-
Risk of arterial thromboembolic events in patients with advanced colorectal cancer receiving bevacizumab
-
Tebbutt NC, Murphy F, Zannino D, et al: Risk of arterial thromboembolic events in patients with advanced colorectal cancer receiving bevacizumab. Ann Oncol 22:1834-1838, 2011
-
(2011)
Ann Oncol
, vol.22
, pp. 1834-1838
-
-
Tebbutt, N.C.1
Murphy, F.2
Zannino, D.3
-
87
-
-
84867047384
-
Addition of aflibercept to fluorouracil, leucovorin, and irinotecan improves survival in a phase III randomized trial in patients with metastatic colorectal cancer previously treated with an oxaliplatin-based regimen
-
Van Cutsem E, Tabernero J, Lakomy R, et al: Addition of aflibercept to fluorouracil, leucovorin, and irinotecan improves survival in a phase III randomized trial in patients with metastatic colorectal cancer previously treated with an oxaliplatin-based regimen. J Clin Oncol 30:3499-3506, 2012
-
(2012)
J Clin Oncol
, vol.30
, pp. 3499-3506
-
-
Van Cutsem, E.1
Tabernero, J.2
Lakomy, R.3
-
88
-
-
84872921660
-
Regorafenib monotherapy for previously treated metastatic colorectal cancer (CORRECT): An international, multicentre, randomised, placebo-controlled, phase 3 trial
-
Grothey A, Van Cutsem E, Sobrero A, et al: Regorafenib monotherapy for previously treated metastatic colorectal cancer (CORRECT): An international, multicentre, randomised, placebo-controlled, phase 3 trial. Lancet 381:303-312, 2013
-
(2013)
Lancet
, vol.381
, pp. 303-312
-
-
Grothey, A.1
Van Cutsem, E.2
Sobrero, A.3
-
89
-
-
84892852372
-
Ramucirumab monotherapy for previously treated advanced gastric or gastro-oesophageal junction adenocarcinoma (REGARD): An international, randomised, multicentre, placebo-controlled, phase 3 trial
-
Fuchs CS, Tomasek J, Yong CJ, et al: Ramucirumab monotherapy for previously treated advanced gastric or gastro-oesophageal junction adenocarcinoma (REGARD): An international, randomised, multicentre, placebo-controlled, phase 3 trial. Lancet 383:31-39, 2014
-
(2014)
Lancet
, vol.383
, pp. 31-39
-
-
Fuchs, C.S.1
Tomasek, J.2
Yong, C.J.3
-
91
-
-
84862575323
-
Predicting the risk of chemotherapy toxicity in older patients: The Chemotherapy Risk Assessment Scale for High-Age Patients (CRASH) score
-
Extermann M, Boler I, Reich RR, et al: Predicting the risk of chemotherapy toxicity in older patients: The Chemotherapy Risk Assessment Scale for High-Age Patients (CRASH) score. Cancer 118:3377-3386, 2012
-
(2012)
Cancer
, vol.118
, pp. 3377-3386
-
-
Extermann, M.1
Boler, I.2
Reich, R.R.3
-
92
-
-
80052704591
-
Predicting chemotherapy toxicity in older adults with cancer: A prospective multicenter study
-
Hurria A, Togawa K, Mohile SG, et al: Predicting chemotherapy toxicity in older adults with cancer: A prospective multicenter study. J Clin Oncol 29:3457-3465, 2011
-
(2011)
J Clin Oncol
, vol.29
, pp. 3457-3465
-
-
Hurria, A.1
Togawa, K.2
Mohile, S.G.3
-
93
-
-
84858833968
-
Call for changes in clinical trial reporting of older patients with cancer
-
Lichtman SM: Call for changes in clinical trial reporting of older patients with cancer. J Clin Oncol 30:893-894, 2012
-
(2012)
J Clin Oncol
, vol.30
, pp. 893-894
-
-
Lichtman, S.M.1
-
94
-
-
84866425915
-
Clinical trial design in older adults with cancer: The need for new paradigms
-
Lichtman SM: Clinical trial design in older adults with cancer: The need for new paradigms. J Geriatr Oncol 3:368-375, 2012
-
(2012)
J Geriatr Oncol
, vol.3
, pp. 368-375
-
-
Lichtman, S.M.1
-
95
-
-
84892463398
-
End points and trial design in geriatric oncology research: A joint European Organisation for Research and Treatment of Cancer-Alliance for Clinical Trials in Oncology-International Society of Geriatric Oncology position article
-
Wildiers H, Mauer M, Pallis A, et al: End points and trial design in geriatric oncology research: A joint European Organisation for Research and Treatment of Cancer-Alliance for Clinical Trials in Oncology-International Society of Geriatric Oncology position article. J Clin Oncol 31:3711-3718, 2013
-
(2013)
J Clin Oncol
, vol.31
, pp. 3711-3718
-
-
Wildiers, H.1
Mauer, M.2
Pallis, A.3
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