메뉴 건너뛰기




Volumn 15, Issue 5, 2006, Pages 584-594

Postmenopausal advanced breast cancer: Options for therapy after tamoxifen and aromatase inhibitors

Author keywords

Advanced breast cancer; Fulvestrant; Hormone receptor positive; Non steroidal AIs; Sequencing

Indexed keywords

AMINOGLUTETHIMIDE; ANASTROZOLE; AROMATASE INHIBITOR; DIETHYLSTILBESTROL; DROLOXIFENE; ESTRADIOL; ESTROGEN; ETHINYLESTRADIOL; EXEMESTANE; FORMESTANE; FULVESTRANT; GESTAGEN; IDOXIFENE; LETROZOLE; MEGESTROL ACETATE; RALOXIFENE; SELECTIVE ESTROGEN RECEPTOR MODULATOR; TAMOXIFEN; TOREMIFENE; VOROZOLE;

EID: 33748573134     PISSN: 09609776     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.breast.2006.01.007     Document Type: Article
Times cited : (58)

References (62)
  • 1
    • 0030070093 scopus 로고    scopus 로고
    • Effect of tamoxifen on bone mineral density measured by dual-energy X- ray absorptiometry in healthy premenopausal and postmenopausal women
    • Powles T.J., Hickish T., Kanis J.A., et al. Effect of tamoxifen on bone mineral density measured by dual-energy X- ray absorptiometry in healthy premenopausal and postmenopausal women. J Clin Oncol 14 (1996) 78-84
    • (1996) J Clin Oncol , vol.14 , pp. 78-84
    • Powles, T.J.1    Hickish, T.2    Kanis, J.A.3
  • 2
    • 0028208456 scopus 로고
    • Endometrial cancer in tamoxifen-treated breast cancer patients: findings from the National Surgical Adjuvant Breast and Bowel Project (NSABP) B-14
    • Fisher B., Costantino J.P., Redmond C.K., et al. Endometrial cancer in tamoxifen-treated breast cancer patients: findings from the National Surgical Adjuvant Breast and Bowel Project (NSABP) B-14. J Natl Cancer Inst 86 (1994) 527-537
    • (1994) J Natl Cancer Inst , vol.86 , pp. 527-537
    • Fisher, B.1    Costantino, J.P.2    Redmond, C.K.3
  • 3
    • 1542346452 scopus 로고    scopus 로고
    • The use of selective estrogen receptor modulators and selective estrogen receptor down-regulators in breast cancer
    • Howell S.J., Johnston S.R., and Howell A. The use of selective estrogen receptor modulators and selective estrogen receptor down-regulators in breast cancer. Best Pract Res Clin Endocrinol Metab 18 (2004) 47-66
    • (2004) Best Pract Res Clin Endocrinol Metab , vol.18 , pp. 47-66
    • Howell, S.J.1    Johnston, S.R.2    Howell, A.3
  • 4
    • 0035991549 scopus 로고    scopus 로고
    • Phase III randomized trial of droloxifene and tamoxifen as first-line endocrine treatment of ER/PgR-positive advanced breast cancer
    • Buzdar A., Hayes D., El-Khoudary A., et al. Phase III randomized trial of droloxifene and tamoxifen as first-line endocrine treatment of ER/PgR-positive advanced breast cancer. Breast Cancer Res Treat 73 (2002) 161-175
    • (2002) Breast Cancer Res Treat , vol.73 , pp. 161-175
    • Buzdar, A.1    Hayes, D.2    El-Khoudary, A.3
  • 5
    • 0028210694 scopus 로고
    • High dose toremifene in advanced breast cancer resistant to or relapsed during tamoxifen treatment
    • Pyrhonen S., Valavaara R., Vuorinen J., and Hajba A. High dose toremifene in advanced breast cancer resistant to or relapsed during tamoxifen treatment. Breast Cancer Res Treat 29 (1994) 223-228
    • (1994) Breast Cancer Res Treat , vol.29 , pp. 223-228
    • Pyrhonen, S.1    Valavaara, R.2    Vuorinen, J.3    Hajba, A.4
  • 6
    • 3042545132 scopus 로고    scopus 로고
    • Aromatase inhibitors in breast cancer
    • Lønning P.E. Aromatase inhibitors in breast cancer. Endocr Relat Cancer 11 (2004) 179-189
    • (2004) Endocr Relat Cancer , vol.11 , pp. 179-189
    • Lønning, P.E.1
  • 7
    • 0038460245 scopus 로고    scopus 로고
    • Phase III study of letrozole versus tamoxifen as first-line therapy of advanced breast cancer in postmenopausal women: analysis of survival and update of efficacy from the International Letrozole Breast Cancer Group
    • Mouridsen H., Gershanovich M., Sun Y., et al. Phase III study of letrozole versus tamoxifen as first-line therapy of advanced breast cancer in postmenopausal women: analysis of survival and update of efficacy from the International Letrozole Breast Cancer Group. J Clin Oncol 21 (2003) 2101-2109
    • (2003) J Clin Oncol , vol.21 , pp. 2101-2109
    • Mouridsen, H.1    Gershanovich, M.2    Sun, Y.3
  • 8
    • 0034669484 scopus 로고    scopus 로고
    • Anastrozole is superior to tamoxifen as first-line therapy for advanced breast cancer in postmenopausal women: results of a North American multicenter randomized trial. Arimidex Study Group
    • Nabholtz J.M., Buzdar A., Pollak M., et al. Anastrozole is superior to tamoxifen as first-line therapy for advanced breast cancer in postmenopausal women: results of a North American multicenter randomized trial. Arimidex Study Group. J Clin Oncol 18 (2000) 3758-3767
    • (2000) J Clin Oncol , vol.18 , pp. 3758-3767
    • Nabholtz, J.M.1    Buzdar, A.2    Pollak, M.3
  • 9
    • 11444251764 scopus 로고    scopus 로고
    • Results of the ATAC (Arimidex, Tamoxifen, Alone or in Combination) trial after completion of 5 years' adjuvant treatment for breast cancer
    • The ATAC Trialists' Group
    • The ATAC Trialists' Group. Results of the ATAC (Arimidex, Tamoxifen, Alone or in Combination) trial after completion of 5 years' adjuvant treatment for breast cancer. Lancet 365 (2005) 60-62
    • (2005) Lancet , vol.365 , pp. 60-62
  • 10
    • 20044382779 scopus 로고    scopus 로고
    • American Society of Clinical Oncology technology assessment on the use of aromatase inhibitors as adjuvant therapy for postmenopausal women with hormone receptor-positive breast cancer: status report 2004
    • Winer E.P., Hudis C., Burstein H.J., et al. American Society of Clinical Oncology technology assessment on the use of aromatase inhibitors as adjuvant therapy for postmenopausal women with hormone receptor-positive breast cancer: status report 2004. J Clin Oncol 23 (2005) 619-629
    • (2005) J Clin Oncol , vol.23 , pp. 619-629
    • Winer, E.P.1    Hudis, C.2    Burstein, H.J.3
  • 11
    • 0034128928 scopus 로고    scopus 로고
    • Exemestane is superior to megestrol acetate after tamoxifen failure in postmenopausal women with advanced breast cancer: results of a phase III randomized double-blind trial. The Exemestane Study Group
    • Kaufmann M., Bajetta E., Dirix L.Y., et al. Exemestane is superior to megestrol acetate after tamoxifen failure in postmenopausal women with advanced breast cancer: results of a phase III randomized double-blind trial. The Exemestane Study Group. J Clin Oncol 18 (2000) 1399-1411
    • (2000) J Clin Oncol , vol.18 , pp. 1399-1411
    • Kaufmann, M.1    Bajetta, E.2    Dirix, L.Y.3
  • 12
    • 7444259675 scopus 로고    scopus 로고
    • A randomized trial of letrozole in postmenopausal women after five years of tamoxifen therapy for early stage breast cancer
    • Goss P.E., Ingle J.N., Martino S., et al. A randomized trial of letrozole in postmenopausal women after five years of tamoxifen therapy for early stage breast cancer. N Engl J Med 349 (2003) 1793-1802
    • (2003) N Engl J Med , vol.349 , pp. 1793-1802
    • Goss, P.E.1    Ingle, J.N.2    Martino, S.3
  • 13
    • 10744223655 scopus 로고    scopus 로고
    • A randomized trial of exemestane after two to three years of tamoxifen therapy in postmenopausal women with primary breast cancer
    • Coombes R.C., Hall E., Gibson L.J., et al. A randomized trial of exemestane after two to three years of tamoxifen therapy in postmenopausal women with primary breast cancer. N Engl J Med 350 (2004) 1081-1092
    • (2004) N Engl J Med , vol.350 , pp. 1081-1092
    • Coombes, R.C.1    Hall, E.2    Gibson, L.J.3
  • 14
    • 0026395885 scopus 로고
    • A potent specific pure antiestrogen with clinical potential
    • Wakeling A.E., Dukes M., and Bowler J. A potent specific pure antiestrogen with clinical potential. Cancer Res 51 (1991) 3867-3873
    • (1991) Cancer Res , vol.51 , pp. 3867-3873
    • Wakeling, A.E.1    Dukes, M.2    Bowler, J.3
  • 15
    • 0037011660 scopus 로고    scopus 로고
    • A phase I trial to assess the pharmacology of the new oestrogen receptor antagonist fulvestrant on the endometrium in healthy postmenopausal volunteers
    • Addo S., Yates R.A., and Laight A. A phase I trial to assess the pharmacology of the new oestrogen receptor antagonist fulvestrant on the endometrium in healthy postmenopausal volunteers. Br J Cancer 87 (2002) 1354-1359
    • (2002) Br J Cancer , vol.87 , pp. 1354-1359
    • Addo, S.1    Yates, R.A.2    Laight, A.3
  • 16
    • 0025084510 scopus 로고
    • Inhibition of estrogen receptor-DNA binding by the "pure" antiestrogen ICI 164,384 appears to be mediated by impaired receptor dimerization
    • Fawell S.E., White R., Hoare S., et al. Inhibition of estrogen receptor-DNA binding by the "pure" antiestrogen ICI 164,384 appears to be mediated by impaired receptor dimerization. Proc Natl Acad Sci USA 87 (1990) 6883-6887
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 6883-6887
    • Fawell, S.E.1    White, R.2    Hoare, S.3
  • 17
    • 0027768899 scopus 로고
    • The antiestrogen ICI 182780 disrupts estrogen receptor nucleocytoplasmic shuttling
    • Dauvois S., White R., and Parker M.G. The antiestrogen ICI 182780 disrupts estrogen receptor nucleocytoplasmic shuttling. J Cell Sci 106 Part 4 (1993) 1377-1388
    • (1993) J Cell Sci , vol.106 , Issue.PART 4 , pp. 1377-1388
    • Dauvois, S.1    White, R.2    Parker, M.G.3
  • 18
    • 0029077113 scopus 로고
    • Responses to pure antiestrogens (ICI 164384, ICI 182780) in estrogen-sensitive and -resistant experimental and clinical breast cancer
    • Nicholson R.I., Gee J.M., Manning D.L., et al. Responses to pure antiestrogens (ICI 164384, ICI 182780) in estrogen-sensitive and -resistant experimental and clinical breast cancer. Ann N Y Acad Sci 761 (1995) 148-163
    • (1995) Ann N Y Acad Sci , vol.761 , pp. 148-163
    • Nicholson, R.I.1    Gee, J.M.2    Manning, D.L.3
  • 19
    • 0029916220 scopus 로고    scopus 로고
    • Short-term effects of pure anti-oestrogen ICI 182780 treatment on oestrogen receptor, epidermal growth factor receptor and transforming growth factor-alpha protein expression in human breast cancer
    • McClelland R.A., Gee J.M., Francis A.B., et al. Short-term effects of pure anti-oestrogen ICI 182780 treatment on oestrogen receptor, epidermal growth factor receptor and transforming growth factor-alpha protein expression in human breast cancer. Eur J Cancer 32A (1996) 413-416
    • (1996) Eur J Cancer , vol.32 A , pp. 413-416
    • McClelland, R.A.1    Gee, J.M.2    Francis, A.B.3
  • 20
    • 1842830729 scopus 로고    scopus 로고
    • Improved antitumor therapy with Herceptin and Faslodex for dual targeting of HER-2 and estrogen receptor signalling pathways in human breast cancers with overexpression of HER-2/neu gene
    • (abs 22)
    • Pietras R.J., Marquez D.C., Chen H.W., et al. Improved antitumor therapy with Herceptin and Faslodex for dual targeting of HER-2 and estrogen receptor signalling pathways in human breast cancers with overexpression of HER-2/neu gene. Breast Cancer Res Treat 82 Suppl. 1 (2003) S12 (abs 22)
    • (2003) Breast Cancer Res Treat , vol.82 , Issue.SUPPL. 1
    • Pietras, R.J.1    Marquez, D.C.2    Chen, H.W.3
  • 21
    • 0035884408 scopus 로고    scopus 로고
    • Comparison of the short-term biological effects of 7alpha-[9-(4,4,5,5,5- pentafluoropentylsulfinyl)-nonyl]estra-1,3,5, (10)-triene-3,17beta-diol (Faslodex) versus tamoxifen in postmenopausal women with primary breast cancer
    • Robertson J.F., Nicholson R.I., Bundred N.J., et al. Comparison of the short-term biological effects of 7alpha-[9-(4,4,5,5,5- pentafluoropentylsulfinyl)-nonyl]estra-1,3,5, (10)-triene-3,17beta-diol (Faslodex) versus tamoxifen in postmenopausal women with primary breast cancer. Cancer Res 61 (2001) 6739-6746
    • (2001) Cancer Res , vol.61 , pp. 6739-6746
    • Robertson, J.F.1    Nicholson, R.I.2    Bundred, N.J.3
  • 22
    • 0036803020 scopus 로고    scopus 로고
    • Development of cDNA microarray for expression profiling of estrogen-responsive genes
    • Inoue A., Yoshida N., Omoto Y., et al. Development of cDNA microarray for expression profiling of estrogen-responsive genes. J Mol Endocrinol 29 (2002) 175-192
    • (2002) J Mol Endocrinol , vol.29 , pp. 175-192
    • Inoue, A.1    Yoshida, N.2    Omoto, Y.3
  • 23
    • 0027463002 scopus 로고
    • Toremifene and tamoxifen in advanced breast cancer-a double-blind cross-over trial
    • Stenbygaard L.E., Herrstedt J., Thomsen J.F., et al. Toremifene and tamoxifen in advanced breast cancer-a double-blind cross-over trial. Breast Cancer Res Treat 25 (1993) 57-63
    • (1993) Breast Cancer Res Treat , vol.25 , pp. 57-63
    • Stenbygaard, L.E.1    Herrstedt, J.2    Thomsen, J.F.3
  • 24
    • 8944237006 scopus 로고    scopus 로고
    • Anastrozole, a potent and selective aromatase inhibitor, versus megestrol acetate in postmenopausal women with advanced breast cancer: results of overview analysis of two phase III trials. Arimidex Study Group
    • Buzdar A., Jonat W., Howell A., et al. Anastrozole, a potent and selective aromatase inhibitor, versus megestrol acetate in postmenopausal women with advanced breast cancer: results of overview analysis of two phase III trials. Arimidex Study Group. J Clin Oncol 14 (1996) 2000-2011
    • (1996) J Clin Oncol , vol.14 , pp. 2000-2011
    • Buzdar, A.1    Jonat, W.2    Howell, A.3
  • 25
    • 0031943424 scopus 로고    scopus 로고
    • Letrozole, a new oral aromatase inhibitor for advanced breast cancer: double-blind randomized trial showing a dose effect and improved efficacy and tolerability compared with megestrol acetate
    • Dombernowsky P., Smith I., Falkson G., et al. Letrozole, a new oral aromatase inhibitor for advanced breast cancer: double-blind randomized trial showing a dose effect and improved efficacy and tolerability compared with megestrol acetate. J Clin Oncol 16 (1998) 453-461
    • (1998) J Clin Oncol , vol.16 , pp. 453-461
    • Dombernowsky, P.1    Smith, I.2    Falkson, G.3
  • 26
    • 7344242595 scopus 로고    scopus 로고
    • Letrozole, a new oral aromatase inhibitor: randomised trial comparing 2.5 mg daily, 0.5 mg daily and aminoglutethimide in postmenopausal women with advanced breast cancer. Letrozole International Trial Group (AR/BC3)
    • Gershanovich M., Chaudri H.A., Campos D., et al. Letrozole, a new oral aromatase inhibitor: randomised trial comparing 2.5 mg daily, 0.5 mg daily and aminoglutethimide in postmenopausal women with advanced breast cancer. Letrozole International Trial Group (AR/BC3). Ann Oncol 9 (1998) 639-645
    • (1998) Ann Oncol , vol.9 , pp. 639-645
    • Gershanovich, M.1    Chaudri, H.A.2    Campos, D.3
  • 27
    • 17444453765 scopus 로고    scopus 로고
    • Efficacy of tamoxifen following anastrozole ('Arimidex') compared with anastrozole following tamoxifen as first-line treatment for advanced breast cancer in postmenopausal women
    • Thürlimann B., Robertson J.F., Nabholtz J.M., et al. Efficacy of tamoxifen following anastrozole ('Arimidex') compared with anastrozole following tamoxifen as first-line treatment for advanced breast cancer in postmenopausal women. Eur J Cancer 39 (2003) 2310-2317
    • (2003) Eur J Cancer , vol.39 , pp. 2310-2317
    • Thürlimann, B.1    Robertson, J.F.2    Nabholtz, J.M.3
  • 28
    • 3342946114 scopus 로고    scopus 로고
    • Anastrozole ('Arimidex') versus tamoxifen as first-line therapy in postmenopausal women with advanced breast cancer: results of the double-blind cross-over SAKK trial 21/95-a sub-study of the TARGET (Tamoxifen or 'Arimidex' Randomized Group Efficacy and Tolerability) trial
    • Thürlimann B., Hess D., Köberle D., et al. Anastrozole ('Arimidex') versus tamoxifen as first-line therapy in postmenopausal women with advanced breast cancer: results of the double-blind cross-over SAKK trial 21/95-a sub-study of the TARGET (Tamoxifen or 'Arimidex' Randomized Group Efficacy and Tolerability) trial. Breast Cancer Res Treat 85 (2004) 247-254
    • (2004) Breast Cancer Res Treat , vol.85 , pp. 247-254
    • Thürlimann, B.1    Hess, D.2    Köberle, D.3
  • 29
    • 27244436804 scopus 로고    scopus 로고
    • Meeting highlights: international expert consensus on the primary therapy of early breast cancer 2005
    • Goldhirsch A., Glick J.H., Gelber R.D., et al. Meeting highlights: international expert consensus on the primary therapy of early breast cancer 2005. Ann Oncol 16 (2005) 1569-1583
    • (2005) Ann Oncol , vol.16 , pp. 1569-1583
    • Goldhirsch, A.1    Glick, J.H.2    Gelber, R.D.3
  • 30
    • 0027358687 scopus 로고
    • Circumvention of tamoxifen resistance by the pure anti-estrogen ICI 182,780
    • Hu X.F., Veroni M., De Luise M., et al. Circumvention of tamoxifen resistance by the pure anti-estrogen ICI 182,780. Int J Cancer 55 (1993) 873-876
    • (1993) Int J Cancer , vol.55 , pp. 873-876
    • Hu, X.F.1    Veroni, M.2    De Luise, M.3
  • 31
    • 0028246412 scopus 로고
    • The importance of tamoxifen metabolism in tamoxifen-stimulated breast tumor growth
    • Osborne C.K., Jarman M., McCague R., et al. The importance of tamoxifen metabolism in tamoxifen-stimulated breast tumor growth. Cancer Chemother Pharmacol 34 (1994) 89-95
    • (1994) Cancer Chemother Pharmacol , vol.34 , pp. 89-95
    • Osborne, C.K.1    Jarman, M.2    McCague, R.3
  • 32
    • 0030016280 scopus 로고    scopus 로고
    • Pharmacokinetics, pharmacological and anti-tumour effects of the specific anti-oestrogen ICI 182780 in women with advanced breast cancer
    • Howell A., DeFriend D.J., Robertson J.F., et al. Pharmacokinetics, pharmacological and anti-tumour effects of the specific anti-oestrogen ICI 182780 in women with advanced breast cancer. Br J Cancer 74 (1996) 300-308
    • (1996) Br J Cancer , vol.74 , pp. 300-308
    • Howell, A.1    DeFriend, D.J.2    Robertson, J.F.3
  • 33
    • 0037102121 scopus 로고    scopus 로고
    • Fulvestrant, formerly ICI 182,780, is as effective as anastrozole in postmenopausal women with advanced breast cancer progressing after prior endocrine treatment
    • Howell A., Robertson J.F.R., Quaresma Albano J., et al. Fulvestrant, formerly ICI 182,780, is as effective as anastrozole in postmenopausal women with advanced breast cancer progressing after prior endocrine treatment. J Clin Oncol 20 (2002) 3396-3403
    • (2002) J Clin Oncol , vol.20 , pp. 3396-3403
    • Howell, A.1    Robertson, J.F.R.2    Quaresma Albano, J.3
  • 34
    • 0037102126 scopus 로고    scopus 로고
    • Double-blind, randomized trial comparing the efficacy and tolerability of fulvestrant versus anastrozole in postmenopausal women with advanced breast cancer progressing on prior endocrine therapy: results of a North American trial
    • Osborne C.K., Pippen J., Jones S.E., et al. Double-blind, randomized trial comparing the efficacy and tolerability of fulvestrant versus anastrozole in postmenopausal women with advanced breast cancer progressing on prior endocrine therapy: results of a North American trial. J Clin Oncol 20 (2002) 3386-3395
    • (2002) J Clin Oncol , vol.20 , pp. 3386-3395
    • Osborne, C.K.1    Pippen, J.2    Jones, S.E.3
  • 35
    • 0038683988 scopus 로고    scopus 로고
    • Fulvestrant versus anastrozole for the treatment of advanced breast carcinoma in postmenopausal women-a prospective combined analysis of two multicenter trials
    • Robertson J.F., Osborne C.K., Howell A., et al. Fulvestrant versus anastrozole for the treatment of advanced breast carcinoma in postmenopausal women-a prospective combined analysis of two multicenter trials. Cancer 98 (2003) 229-238
    • (2003) Cancer , vol.98 , pp. 229-238
    • Robertson, J.F.1    Osborne, C.K.2    Howell, A.3
  • 36
    • 22244449598 scopus 로고    scopus 로고
    • Fulvestrant versus anastrozole for the treatment of advanced breast carcinoma: a prospectively planned combined survival analysis of two multicenter trials
    • Howell A., Pippen J., Elledge R.M., et al. Fulvestrant versus anastrozole for the treatment of advanced breast carcinoma: a prospectively planned combined survival analysis of two multicenter trials. Cancer 104 (2005) 236-239
    • (2005) Cancer , vol.104 , pp. 236-239
    • Howell, A.1    Pippen, J.2    Elledge, R.M.3
  • 37
    • 0038240962 scopus 로고    scopus 로고
    • Fulvestrant (Faslodex) versus anastrozole for the second-line treatment of subgroups of postmenopausal women with visceral and non-visceral metastases: combined results from two multicentre trials
    • Mauriac L., Pippen J.E., Quaresma Albano J., et al. Fulvestrant (Faslodex) versus anastrozole for the second-line treatment of subgroups of postmenopausal women with visceral and non-visceral metastases: combined results from two multicentre trials. Eur J Cancer 39 (2003) 1228-1233
    • (2003) Eur J Cancer , vol.39 , pp. 1228-1233
    • Mauriac, L.1    Pippen, J.E.2    Quaresma Albano, J.3
  • 38
    • 0038356602 scopus 로고    scopus 로고
    • Postmenopausal women who progress on fulvestrant ('Faslodex') remain sensitive to further endocrine therapy
    • Vergote I., Robertson J.F.R., Kleeberg U., et al. Postmenopausal women who progress on fulvestrant ('Faslodex') remain sensitive to further endocrine therapy. Breast Cancer Res Treat 79 (2003) 207-211
    • (2003) Breast Cancer Res Treat , vol.79 , pp. 207-211
    • Vergote, I.1    Robertson, J.F.R.2    Kleeberg, U.3
  • 39
    • 0036702132 scopus 로고    scopus 로고
    • Molecular changes associated with the acquisition of oestrogen hypersensitivity in MCF-7 breast cancer cells on long-term oestrogen deprivation
    • Chan C.M., Martin L.A., Johnston S.R., et al. Molecular changes associated with the acquisition of oestrogen hypersensitivity in MCF-7 breast cancer cells on long-term oestrogen deprivation. J Steroid Biochem Mol Biol 81 (2002) 333-341
    • (2002) J Steroid Biochem Mol Biol , vol.81 , pp. 333-341
    • Chan, C.M.1    Martin, L.A.2    Johnston, S.R.3
  • 40
    • 0042232592 scopus 로고    scopus 로고
    • Enhanced estrogen receptor (ER) alpha, ERBB2, and MAPK signal transduction pathways operate during the adaptation of MCF-7 cells to long term estrogen deprivation
    • Martin L.A., Farmer I., Johnston S.R., et al. Enhanced estrogen receptor (ER) alpha, ERBB2, and MAPK signal transduction pathways operate during the adaptation of MCF-7 cells to long term estrogen deprivation. J Biol Chem 278 (2003) 30458-30468
    • (2003) J Biol Chem , vol.278 , pp. 30458-30468
    • Martin, L.A.1    Farmer, I.2    Johnston, S.R.3
  • 41
    • 1842505162 scopus 로고    scopus 로고
    • Aromatase inhibitors for breast cancer in postmenopausal women
    • Campos S.M. Aromatase inhibitors for breast cancer in postmenopausal women. Oncologist 9 (2004) 126-136
    • (2004) Oncologist , vol.9 , pp. 126-136
    • Campos, S.M.1
  • 42
    • 0030748661 scopus 로고    scopus 로고
    • Endocrine and clinical effects of exemestane (PNU 155971), a novel steroidal aromatase inhibitor, in postmenopausal breast cancer patients: a phase I study
    • Johannessen D.C., Engan T., Salle E.D., et al. Endocrine and clinical effects of exemestane (PNU 155971), a novel steroidal aromatase inhibitor, in postmenopausal breast cancer patients: a phase I study. Clin Cancer Res 3 (1997) 1101-1108
    • (1997) Clin Cancer Res , vol.3 , pp. 1101-1108
    • Johannessen, D.C.1    Engan, T.2    Salle, E.D.3
  • 43
    • 0024826169 scopus 로고
    • Improved measurement of androgen receptors in human breast cancer
    • Lea O.A., Kvinnsland S., and Thorsen T. Improved measurement of androgen receptors in human breast cancer. Cancer Res 49 (1989) 7162-7167
    • (1989) Cancer Res , vol.49 , pp. 7162-7167
    • Lea, O.A.1    Kvinnsland, S.2    Thorsen, T.3
  • 44
    • 0000990650 scopus 로고    scopus 로고
    • Sequential use of aromatase inactivators and inhibitors in advanced breast cancer
    • (abs 238)
    • Bertelli G., Garrone O., and Merlano M. Sequential use of aromatase inactivators and inhibitors in advanced breast cancer. Proc Am Soc Clin Oncol 21 (2002) 60a (abs 238)
    • (2002) Proc Am Soc Clin Oncol , vol.21
    • Bertelli, G.1    Garrone, O.2    Merlano, M.3
  • 45
    • 0242534026 scopus 로고    scopus 로고
    • Exemestane (EXE) is an effective 3rd line hormonal therapy for postmenopausal metastatic breast cancer (MBC) patients (pts) pretreated with 3rd generation non steroidal aromatase inhibitors (nSAI)
    • Carlini P., Michelotti A., Giannarelli D., et al. Exemestane (EXE) is an effective 3rd line hormonal therapy for postmenopausal metastatic breast cancer (MBC) patients (pts) pretreated with 3rd generation non steroidal aromatase inhibitors (nSAI). Ann Oncol 13 Suppl. 5 (2002) 48
    • (2002) Ann Oncol , vol.13 , Issue.SUPPL. 5 , pp. 48
    • Carlini, P.1    Michelotti, A.2    Giannarelli, D.3
  • 46
    • 8344243109 scopus 로고    scopus 로고
    • Exemestane in metastatic breast cancer: effective therapy after 3rd generation aromatase inhibitor failure
    • (abs 435)
    • Fernie N.L., Zekri J.M., Leonard R.C.F., et al. Exemestane in metastatic breast cancer: effective therapy after 3rd generation aromatase inhibitor failure. Breast Cancer Res Treat 82 Suppl. 1 (2003) S104 (abs 435)
    • (2003) Breast Cancer Res Treat , vol.82 , Issue.SUPPL. 1
    • Fernie, N.L.1    Zekri, J.M.2    Leonard, R.C.F.3
  • 47
    • 17144472154 scopus 로고    scopus 로고
    • Activity of exemestane in metastatic breast cancer after failure of nonsteroidal aromatase inhibitors: a phase II trial
    • Lønning P.E., Bajetta E., Murray R., et al. Activity of exemestane in metastatic breast cancer after failure of nonsteroidal aromatase inhibitors: a phase II trial. J Clin Oncol 18 (2000) 2234-2244
    • (2000) J Clin Oncol , vol.18 , pp. 2234-2244
    • Lønning, P.E.1    Bajetta, E.2    Murray, R.3
  • 48
    • 0345596372 scopus 로고    scopus 로고
    • Third-line hormonal treatment with exemestane in postmenopausal patients with advanced breast cancer progressing on aminoglutethimide: a phase II multicentre multinational study. Exemestane Study Group
    • Thürlimann B., Paridaens R., Serin D., et al. Third-line hormonal treatment with exemestane in postmenopausal patients with advanced breast cancer progressing on aminoglutethimide: a phase II multicentre multinational study. Exemestane Study Group. Eur J Cancer 33 (1997) 1767-1773
    • (1997) Eur J Cancer , vol.33 , pp. 1767-1773
    • Thürlimann, B.1    Paridaens, R.2    Serin, D.3
  • 49
    • 0029031797 scopus 로고
    • Aromatase inhibition with 4-OHAndrostenedione after prior aromatase inhibition with aminoglutethimide in women with advanced breast cancer
    • Murray R., and Pitt P. Aromatase inhibition with 4-OHAndrostenedione after prior aromatase inhibition with aminoglutethimide in women with advanced breast cancer. Breast Cancer Res Treat 35 (1995) 249-253
    • (1995) Breast Cancer Res Treat , vol.35 , pp. 249-253
    • Murray, R.1    Pitt, P.2
  • 50
    • 0030007732 scopus 로고    scopus 로고
    • Treatment with formestane alone and in combination with aminoglutethimide in heavily pretreated breast cancer patients: clinical and endocrine effects
    • Geisler J., Johannessen D.C., Anker G., and Lønning P.E. Treatment with formestane alone and in combination with aminoglutethimide in heavily pretreated breast cancer patients: clinical and endocrine effects. Eur J Cancer 32A (1996) 789-792
    • (1996) Eur J Cancer , vol.32 A , pp. 789-792
    • Geisler, J.1    Johannessen, D.C.2    Anker, G.3    Lønning, P.E.4
  • 51
    • 0032999446 scopus 로고    scopus 로고
    • Anastrozole shows evidence of activity in postmenopausal patients who have responded or stabilised on formestane therapy
    • Harper-Wynne C., and Coombes R.C. Anastrozole shows evidence of activity in postmenopausal patients who have responded or stabilised on formestane therapy. Eur J Cancer 35 (1999) 744-746
    • (1999) Eur J Cancer , vol.35 , pp. 744-746
    • Harper-Wynne, C.1    Coombes, R.C.2
  • 52
    • 0017102124 scopus 로고
    • The effects of estrogens and antiestrogens on hormone-responsive human breast cancer in long-term tissue culture
    • Lippman M., Bolan G., and Huff K. The effects of estrogens and antiestrogens on hormone-responsive human breast cancer in long-term tissue culture. Cancer Res 36 (1976) 4595-4601
    • (1976) Cancer Res , vol.36 , pp. 4595-4601
    • Lippman, M.1    Bolan, G.2    Huff, K.3
  • 53
    • 0028853923 scopus 로고
    • Estrogen deprivation causes estradiol hypersensitivity in human breast cancer cells
    • Masamura S., Santner S.J., Heitjan D.F., and Santen R.J. Estrogen deprivation causes estradiol hypersensitivity in human breast cancer cells. J Clin Endocrinol Metab 80 (1995) 2918-2925
    • (1995) J Clin Endocrinol Metab , vol.80 , pp. 2918-2925
    • Masamura, S.1    Santner, S.J.2    Heitjan, D.F.3    Santen, R.J.4
  • 54
    • 0034891355 scopus 로고    scopus 로고
    • High-dose estrogen treatment in postmenopausal breast cancer patients heavily exposed to endocrine treatment
    • Lønning P.E., Taylor P.D., Anker G., et al. High-dose estrogen treatment in postmenopausal breast cancer patients heavily exposed to endocrine treatment. Breast Cancer Res Treat 67 (2001) 111-116
    • (2001) Breast Cancer Res Treat , vol.67 , pp. 111-116
    • Lønning, P.E.1    Taylor, P.D.2    Anker, G.3
  • 55
    • 0035992421 scopus 로고    scopus 로고
    • The effect of second-line antiestrogen therapy on breast tumor growth after first-line treatment with the aromatase inhibitor letrozole: long-term studies using the intratumoral aromatase postmenopausal breast cancer model
    • Long B.J., Jelovac D., Thiantanawat A., and Brodie A.M. The effect of second-line antiestrogen therapy on breast tumor growth after first-line treatment with the aromatase inhibitor letrozole: long-term studies using the intratumoral aromatase postmenopausal breast cancer model. Clin Cancer Res 8 (2002) 2378-2388
    • (2002) Clin Cancer Res , vol.8 , pp. 2378-2388
    • Long, B.J.1    Jelovac, D.2    Thiantanawat, A.3    Brodie, A.M.4
  • 56
    • 0041325578 scopus 로고    scopus 로고
    • Fulvestrant ('Faslodex') as hormonal treatment in postmenopausal patients with advanced breast cancer progressing after treatment with tamoxifen and aromatase inhibitors
    • (abs 249)
    • Perey L., Thürlimann B., Hawle H., et al. Fulvestrant ('Faslodex') as hormonal treatment in postmenopausal patients with advanced breast cancer progressing after treatment with tamoxifen and aromatase inhibitors. Breast Cancer Res Treat 76 Suppl. 1 (2002) S72 (abs 249)
    • (2002) Breast Cancer Res Treat , vol.76 , Issue.SUPPL. 1
    • Perey, L.1    Thürlimann, B.2    Hawle, H.3
  • 57
    • 18944402975 scopus 로고    scopus 로고
    • Fulvestrant (Faslodex™) as hormonal treatment in postmenopausal patients with advanced breast cancer (ABC) progressing after treatment with tamoxifen and aromatase inhibitors: update of a phase II SAKK trial
    • abs 6048
    • Perey L., Paridaens R., Nolé F., et al. Fulvestrant (Faslodex™) as hormonal treatment in postmenopausal patients with advanced breast cancer (ABC) progressing after treatment with tamoxifen and aromatase inhibitors: update of a phase II SAKK trial. Breast Cancer Res Treat 88 Suppl. 1 (2004) S236 abs 6048
    • (2004) Breast Cancer Res Treat , vol.88 , Issue.SUPPL. 1
    • Perey, L.1    Paridaens, R.2    Nolé, F.3
  • 58
    • 18944365812 scopus 로고    scopus 로고
    • Evaluation of fulvestrant in women with advanced breast cancer and progression on prior aromatase inhibitor therapy: a phase II trial of the North Central Cancer Treatment Group
    • (abs 409)
    • Ingle J.N., Rowland K.M., Suman V.J., et al. Evaluation of fulvestrant in women with advanced breast cancer and progression on prior aromatase inhibitor therapy: a phase II trial of the North Central Cancer Treatment Group. Breast Cancer Res Treat 88 Suppl. 1 (2004) S38 (abs 409)
    • (2004) Breast Cancer Res Treat , vol.88 , Issue.SUPPL. 1
    • Ingle, J.N.1    Rowland, K.M.2    Suman, V.J.3
  • 59
    • 1842717914 scopus 로고    scopus 로고
    • ®) demonstrates clinical benefit in heavily pretreated postmenopausal women with advanced breast cancer: a single-center experience
    • (abs 439)
    • ®) demonstrates clinical benefit in heavily pretreated postmenopausal women with advanced breast cancer: a single-center experience. Breast Cancer Res Treat 82 Suppl. 1 (2003) S105 (abs 439)
    • (2003) Breast Cancer Res Treat , vol.82 , Issue.SUPPL. 1
    • Franco, S.1    Perez, A.2    Tan-Chiu, E.3
  • 60
    • 8344263533 scopus 로고    scopus 로고
    • Fulvestrant in postmenopausal women with metastatic breast cancer progressing on prior endocrine therapy-results from an expanded access programme
    • (abs 264)
    • Petruzelka L., and Zimovjanova M. Fulvestrant in postmenopausal women with metastatic breast cancer progressing on prior endocrine therapy-results from an expanded access programme. Eur J Cancer Suppl. 2 (2004) 132 (abs 264)
    • (2004) Eur J Cancer , Issue.SUPPL. 2 , pp. 132
    • Petruzelka, L.1    Zimovjanova, M.2
  • 62
    • 33749440838 scopus 로고    scopus 로고
    • Fulvestrant after aromatase inhibitor failure: results from the expanded access program in Rio de Janeiro, Brazil
    • Cardoso A.A., Mendes G.Q., Froimtchuk M.J., et al. Fulvestrant after aromatase inhibitor failure: results from the expanded access program in Rio de Janeiro, Brazil. Breast Cancer Res Treat 88 Suppl. 1 (2004) S237
    • (2004) Breast Cancer Res Treat , vol.88 , Issue.SUPPL. 1
    • Cardoso, A.A.1    Mendes, G.Q.2    Froimtchuk, M.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.