Under-representation of older adults in cancer registration trials: Known problem, little progress

Journal of Clinical Oncology

Volumn 30, Issue 17, 2012, Pages 2036-2038

  Scher, Kevin S ^a   Hurria, Arti ^a  

^a CITY OF HOPE NATIONAL MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BENDAMUSTINE; BEVACIZUMAB; BORTEZOMIB; CABAZITAXEL; CAPECITABINE; CARBOPLATIN; CETUXIMAB; CISPLATIN; CYCLOPHOSPHAMIDE; DEGARELIX; DENILEUKIN DIFTITOX; ELTROMBOPAG; ERLOTINIB; EVEROLIMUS; FLUDARABINE; FLUOROURACIL; GEMCITABINE; IMATINIB; INTERFERON; IXABEPILONE; LAPATINIB; LETROZOLE; NILOTINIB; OFATUMUMAB; PACLITAXEL; PAZOPANIB; PEMETREXED; PLERIXAFOR; PRALATREXATE; PREDNISONE; RITUXIMAB; ROMIDEPSIN; ROMIPLOSTIM; SORAFENIB; TEMSIROLIMUS; UNINDEXED DRUG;

BREAST METASTASIS; CANCER PATIENT; CANCER REGISTRY; CHRONIC LYMPHATIC LEUKEMIA; CHRONIC MYELOID LEUKEMIA; COLON CANCER; COMORBIDITY; CUTANEOUS T CELL LYMPHOMA; DRUG APPROVAL; ELDERLY CARE; FOLLICULAR LYMPHOMA; GASTROINTESTINAL STROMAL TUMOR; GLIOBLASTOMA; HUMAN; IDIOPATHIC THROMBOCYTOPENIC PURPURA; KIDNEY CANCER; KIDNEY CARCINOMA; KNOWLEDGE; LARGE CELL LYMPHOMA; LIVER CELL CARCINOMA; LUNG CANCER; LUNG NON SMALL CELL CANCER; MULTIPLE MYELOMA; NONHODGKIN LYMPHOMA; NOTE; PANCREAS CANCER; PERIPHERAL T CELL LYMPHOMA; PRIORITY JOURNAL; PROSTATE CANCER; RISK BENEFIT ANALYSIS; SOCIAL SUPPORT; UNITED STATES;

AGED; ANTINEOPLASTIC AGENTS; CLINICAL TRIALS AS TOPIC; DRUG APPROVAL; GERIATRICS; HUMANS; MEDICAL ONCOLOGY; NEOPLASMS; PATIENT PARTICIPATION; PATIENT SELECTION; SEER PROGRAM; UNITED STATES;

EID: 84863889174     PISSN: 0732183X     EISSN: 15277755     Source Type: Journal    
DOI: 10.1200/JCO.2012.41.6727     Document Type: Note

References (5)

1. Smith BD, Smith GL, Hurria A, et al: Future of cancer incidence in the United States: Burdens upon an aging, changing nation. J Clin Oncol 27:2758-2765, 2009
2. Center for the Study of Drugs Likely to Be Used in the Elderly: Guideline for the Study of Drugs Likely to Be Used in the Elderly. Washington, DC, US Department of Health and Human Services, 1989
3. Talarico L, Chen G, Pazdur R: Enrollment of elderly patients in clinical trials for cancer drug registration: A 7-year experience by the US Food and Drug Administration. J Clin Oncol 22:4626-4631, 2004 (Pubitemid 41185131)
4. Hurria A, Cohen HJ, Extermann M: Geriatric Oncology Research in the Cooperative Groups: A Report of a SIOG Special Meeting. J Geriatr Oncol 1:40-44, 2010
5. Kornblith AB, Kemeny M, Peterson BL, et al: Survey of oncologists'perceptions of barriers to accrual of older patients with breast carcinoma to clinical trials. Cancer 95:989-996, 2002 (Pubitemid 34925347)