Altered proteostasis in aging and heat shock response in C. elegans revealed by analysis of the global and de novo synthesized proteome

Cellular and Molecular Life Sciences

Volumn 71, Issue 17, 2014, Pages 3339-3361

  Liang, Vanessa ^a   Ullrich, Milena ^a,b   Lam, Hong ^a   Chew, Yee Lian ^a   Banister, Samuel ^a   Song, Xiaomin ^c   Zaw, Thiri ^c   Kassiou, Michael ^a   Götz, Jürgen ^a,d   Nicholas, Hannah R ^a  

^a UNIVERSITY OF SYDNEY   (Australia)

^b CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^c MACQUARIE UNIVERSITY   (Australia)

^d UNIVERSITY OF QUEENSLAND   (Australia)

Author keywords

Aging; C. elegans; Click chemistry; Heat shock proteins; iTRAQ quantitative mass spectrometry; Ribosomal proteins

Indexed keywords

60S RIBOSOMAL PROTEIN 44; 60S RIBOSOMAL PROTEIN L14; 60S RIBOSOMAL PROTEIN L21; 60S RIBOSOMAL PROTEIN L22; 60S RIBOSOMAL PROTEIN L23A 1; 60S RIBOSOMAL PROTEIN L27A; 60S RIBOSOMAL PROTEIN L36; 60S RIBOSOMAL PROTEIN L4; 60S RIBOSOMAL PROTEIN S13; 60S RIBOSOMAL PROTEIN S8; ATP SYNTHASE B HOMOLOG; ATP SYNTHASE SUBUNIT BETA; ATP SYNTHASE SUBUNIT G2; AZIDOHOMOALANINE; CHAPERONIN 60; HEAT SHOCK PROTEIN 100; HEAT SHOCK PROTEIN 70; METHIONINE DERIVATIVE; PROTEOME; PROTON TRANSPORTING ADENOSINE TRIPHOSPHATE SYNTHASE; RIBOSOME PROTEIN; UBIQUINOL CYTOCHROME C REDUCTASE; UNCLASSIFIED DRUG; VITELLOGENIN; VITELLOGENIN 1; VITELLOGENIN 2; VITELLOGENIN 3; VITELLOGENIN 4; VITELLOGENIN 5; VITELLOGENIN 6;

ADULT; AGING; ARTICLE; CAENORHABDITIS ELEGANS; CITRIC ACID CYCLE; CLICK CHEMISTRY; CONTROLLED STUDY; HEAT SHOCK RESPONSE; ISOBARIC TAGS FOR RELATIVE AND ABSOLUTE QUANTITATION; MASS SPECTROMETRY; NONHUMAN; PROTEIN AGGREGATION; PROTEIN ANALYSIS; PROTEIN HOMEOSTASIS; PROTEIN MISFOLDING; PROTEIN STRUCTURE; PROTEIN SYNTHESIS; RESPIRATORY CHAIN; YOUNG ADULT;

ANIMALIA; CAENORHABDITIS ELEGANS;

AGING; ALANINE; ANIMALS; BLOTTING, WESTERN; CAENORHABDITIS ELEGANS; CAENORHABDITIS ELEGANS PROTEINS; CLICK CHEMISTRY; FORECASTING; GENE EXPRESSION REGULATION; GENES, HELMINTH; HEAT-SHOCK RESPONSE; HOT TEMPERATURE; MASS SPECTROMETRY; MICROSCOPY, FLUORESCENCE; PROTEIN FOLDING; PROTEOME; PROTEOSTASIS DEFICIENCIES;

EID: 84906220352     PISSN: 1420682X     EISSN: 14209071     Source Type: Journal    
DOI: 10.1007/s00018-014-1558-7     Document Type: Article

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