메뉴 건너뛰기




Volumn 193, Issue 4, 2014, Pages 1645-1653

γδT cells drive myeloid-derived suppressor cell-mediated CD8+ T cell exhaustion in hepatitis B virus-induced immunotolerance

Author keywords

[No Author keywords available]

Indexed keywords

ARGINASE 1; CD11B ANTIGEN; CYTOKINE; INTERLEUKIN 17;

EID: 84905984580     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1303432     Document Type: Article
Times cited : (96)

References (38)
  • 1
    • 39549097751 scopus 로고    scopus 로고
    • Liver: An organ with predominant innate immunity
    • Gao, B., W. I. Jeong, and Z. Tian. 2008. Liver: An organ with predominant innate immunity. Hepatology 47: 729-736.
    • (2008) Hepatology , vol.47 , pp. 729-736
    • Gao, B.1    Jeong, W.I.2    Tian, Z.3
  • 2
    • 0028916425 scopus 로고
    • Hepatitis B virus immunopathogenesis
    • Chisari, F. V., and C. Ferrari. 1995. Hepatitis B virus immunopathogenesis. Annu. Rev. Immunol. 13: 29-60.
    • (1995) Annu. Rev. Immunol , vol.13 , pp. 29-60
    • Chisari, F.V.1    Ferrari, C.2
  • 3
    • 0034678435 scopus 로고    scopus 로고
    • The role of virus-specific CD8(+) cells in liver damage and viral control during persistent hepatitis B virus infection
    • Maini, M. K., C. Boni, C. K. Lee, J. R. Larrubia, S. Reignat, G. S. Ogg, A. S. King, J. Herberg, R. Gilson, A. Alisa, et al. 2000. The role of virus-specific CD8(+) cells in liver damage and viral control during persistent hepatitis B virus infection. J. Exp. Med. 191: 1269-1280.
    • (2000) J. Exp. Med , vol.191 , pp. 1269-1280
    • Maini, M.K.1    Boni, C.2    Lee, C.K.3    Larrubia, J.R.4    Reignat, S.5    Ogg, G.S.6    King, A.S.7    Herberg, J.8    Gilson, R.9    Alisa, A.10
  • 4
    • 84879601220 scopus 로고    scopus 로고
    • Therapeutic recovery of hepatitis B virus (HBV)-induced hepatocyte-intrinsic immune defect reverses systemic adaptive immune tolerance
    • Lan, P., C. Zhang, Q. Han, J. Zhang, and Z. Tian. 2013. Therapeutic recovery of hepatitis B virus (HBV)-induced hepatocyte-intrinsic immune defect reverses systemic adaptive immune tolerance. Hepatology 58: 73-85.
    • (2013) Hepatology , vol.58 , pp. 73-85
    • Lan, P.1    Zhang, C.2    Han, Q.3    Zhang, J.4    Tian, Z.5
  • 5
    • 84983720423 scopus 로고    scopus 로고
    • PD-1 blockage reverses immune dysfunction and hepatitis B viral persistence in a mouse animal model
    • Tzeng, H.-T., H.-F. Tsai, H.-J. Liao, Y.-J. Lin, L. Chen, P.-J. Chen, and P.-N. Hsu. 2012. PD-1 blockage reverses immune dysfunction and hepatitis B viral persistence in a mouse animal model. PLoS ONE 7: e39179.
    • (2012) PLoS ONE , vol.7
    • Tzeng, H.-T.1    Tsai, H.-F.2    Liao, H.-J.3    Lin, Y.-J.4    Chen, L.5    Chen, P.-J.6    Hsu, P.-N.7
  • 6
    • 84865531623 scopus 로고    scopus 로고
    • Foxp3+ regulatory T cells protect the liver from immune damage and compromise virus control during acute experimental hepatitis B virus infection in mice
    • Stross, L., J. Günther, G. Gasteiger, T. Asen, S. Graf, M. Aichler, I. Esposito, D. H. Busch, P. Knolle, T. Sparwasser, and U. Protzer. 2012. Foxp3+ regulatory T cells protect the liver from immune damage and compromise virus control during acute experimental hepatitis B virus infection in mice. Hepatology 56: 873-883.
    • (2012) Hepatology , vol.56 , pp. 873-883
    • Stross, L.1    Günther, J.2    Gasteiger, G.3    Asen, T.4    Graf, S.5    Aichler, M.6    Esposito, I.7    Busch, D.H.8    Knolle, P.9    Sparwasser, T.10    Protzer, U.11
  • 7
    • 61349100687 scopus 로고    scopus 로고
    • Myeloid-derived suppressor cells as regulators of the immune system
    • Gabrilovich, D. I., and S. Nagaraj. 2009. Myeloid-derived suppressor cells as regulators of the immune system. Nat. Rev. Immunol. 9: 162-174.
    • (2009) Nat. Rev. Immunol , vol.9 , pp. 162-174
    • Gabrilovich, D.I.1    Nagaraj, S.2
  • 8
    • 77951936316 scopus 로고    scopus 로고
    • IL-17 promotes tumor development through the induction of tumor promoting microenvironments at tumor sites and myeloid-derived suppressor cells
    • He, D., H. Li, N. Yusuf, C. A. Elmets, J. Li, J. D. Mountz, and H. Xu. 2010. IL-17 promotes tumor development through the induction of tumor promoting microenvironments at tumor sites and myeloid-derived suppressor cells. J. Immunol. 184: 2281-2288.
    • (2010) J. Immunol , vol.184 , pp. 2281-2288
    • He, D.1    Li, H.2    Yusuf, N.3    Elmets, C.A.4    Li, J.5    Mountz, J.D.6    Xu, H.7
  • 9
    • 84874260474 scopus 로고    scopus 로고
    • Chronic but not acute virus infection induces sustained expansion of myeloid suppressor cell numbers that inhibit viral-specific T cell immunity
    • Norris, B. A., L. S. Uebelhoer, H. I. Nakaya, A. A. Price, A. Grakoui, and B. Pulendran. 2013. Chronic but not acute virus infection induces sustained expansion of myeloid suppressor cell numbers that inhibit viral-specific T cell immunity. Immunity 38: 309-321.
    • (2013) Immunity , vol.38 , pp. 309-321
    • Norris, B.A.1    Uebelhoer, L.S.2    Nakaya, H.I.3    Price, A.A.4    Grakoui, A.5    Pulendran, B.6
  • 10
    • 84863012062 scopus 로고    scopus 로고
    • Myeloid suppressor cells induced by hepatitis C virus suppress T-cell responses through the production of reactive oxygen species
    • Tacke, R. S., H. C. Lee, C. Goh, J. Courtney, S. J. Polyak, H. R. Rosen, and Y. S. Hahn. 2012. Myeloid suppressor cells induced by hepatitis C virus suppress T-cell responses through the production of reactive oxygen species. Hepatology 55: 343-353.
    • (2012) Hepatology , vol.55 , pp. 343-353
    • Tacke, R.S.1    Lee, H.C.2    Goh, C.3    Courtney, J.4    Polyak, S.J.5    Rosen, H.R.6    Hahn, Y.S.7
  • 11
    • 0037363585 scopus 로고    scopus 로고
    • Immunoregulation in the tissues by gammadelta T cells
    • Hayday, A., and R. Tigelaar. 2003. Immunoregulation in the tissues by gammadelta T cells. Nat. Rev. Immunol. 3: 233-242.
    • (2003) Nat. Rev. Immunol , vol.3 , pp. 233-242
    • Hayday, A.1    Tigelaar, R.2
  • 12
    • 81455141970 scopus 로고    scopus 로고
    • Vg4 gd T cell-derived IL-17A negatively regulates NKT cell function in Con A-induced fulminant hepatitis
    • Zhao, N., J. Hao, Y. Ni, W. Luo, R. Liang, G. Cao, Y. Zhao, P. Wang, L. Zhao, Z. Tian, et al. 2011. Vg4 gd T cell-derived IL-17A negatively regulates NKT cell function in Con A-induced fulminant hepatitis. J. Immunol. 187: 5007-5014.
    • (2011) J. Immunol , vol.187 , pp. 5007-5014
    • Zhao, N.1    Hao, J.2    Ni, Y.3    Luo, W.4    Liang, R.5    Cao, G.6    Zhao, Y.7    Wang, P.8    Zhao, L.9    Tian, Z.10
  • 13
    • 0029417039 scopus 로고
    • Anti-g d T cell antibody blocks the induction and maintenance of oral tolerance to ovalbumin in mice
    • Mengel, J., F. Cardillo, L. S. Aroeira, O. Williams, M. Russo, and N. M. Vaz. 1995. Anti-g d T cell antibody blocks the induction and maintenance of oral tolerance to ovalbumin in mice. Immunol. Lett. 48: 97-102.
    • (1995) Immunol. Lett , vol.48 , pp. 97-102
    • Mengel, J.1    Cardillo, F.2    Aroeira, L.S.3    Williams, O.4    Russo, M.5    Vaz, N.M.6
  • 14
    • 0031569452 scopus 로고    scopus 로고
    • Gamma delta T lymphocytes regulate the induction and maintenance of oral tolerance
    • Ke, Y., K. Pearce, J. P. Lake, H. K. Ziegler, and J. A. Kapp. 1997. Gamma delta T lymphocytes regulate the induction and maintenance of oral tolerance. J. Immunol. 158: 3610-3618.
    • (1997) J. Immunol , vol.158 , pp. 3610-3618
    • Ke, Y.1    Pearce, K.2    Lake, J.P.3    Ziegler, H.K.4    Kapp, J.A.5
  • 15
    • 0035080601 scopus 로고    scopus 로고
    • Role of T lymphocytes in rat 2,4,6-trinitrobenzene sulphonic acid (TNBS) induced colitis: Increased mortality after gammadelta T cell depletion and no effect of alphabeta T cell depletion
    • Hoffmann, J. C., K. Peters, S. Henschke, B. Herrmann, K. Pfister, J.Westermann, and M. Zeitz. 2001. Role of T lymphocytes in rat 2,4,6-trinitrobenzene sulphonic acid (TNBS) induced colitis: increased mortality after gammadelta T cell depletion and no effect of alphabeta T cell depletion. Gut 48: 489-495.
    • (2001) Gut , vol.48 , pp. 489-495
    • Hoffmann, J.C.1    Peters, K.2    Henschke, S.3    Herrmann, B.4    Pfister, K.5    Westermann, J.6    Zeitz, M.7
  • 17
    • 84885070815 scopus 로고    scopus 로고
    • Decreased Vd2 gd T cells associated with liver damage by regulation of Th17 response in patients with chronic hepatitis B
    • Wu, X., J.-Y. Zhang, A. Huang, Y.-Y. Li, S. Zhang, J. Wei, S. Xia, Y. Wan, W. Chen, and Z. Zhang. 2013. Decreased Vd2 gd T cells associated with liver damage by regulation of Th17 response in patients with chronic hepatitis B. J. Infect. Dis. 208: 1294-1304.
    • (2013) J. Infect. Dis , vol.208 , pp. 1294-1304
    • Wu, X.1    Zhang, J.-Y.2    Huang, A.3    Li, Y.-Y.4    Zhang, S.5    Wei, J.6    Xia, S.7    Wan, Y.8    Chen, W.9    Zhang, Z.10
  • 18
    • 56649112958 scopus 로고    scopus 로고
    • Characteristics of circulating T cell receptor gammadelta T cells from individuals chronically infected with hepatitis B virus (HBV): An association between V(delta)2 subtype and chronic HBV infection
    • Chen, M., D. Zhang, W. Zhen, Q. Shi, Y. Liu, N. Ling, M. Peng, K. Tang, P. Hu, H. Hu, and H. Ren. 2008. Characteristics of circulating T cell receptor gammadelta T cells from individuals chronically infected with hepatitis B virus (HBV): an association between V(delta)2 subtype and chronic HBV infection. J. Infect. Dis. 198: 1643-1650.
    • (2008) J. Infect. Dis , vol.198 , pp. 1643-1650
    • Chen, M.1    Zhang, D.2    Zhen, W.3    Shi, Q.4    Liu, Y.5    Ling, N.6    Peng, M.7    Tang, K.8    Hu, P.9    Hu, H.10    Ren, H.11
  • 19
    • 84983721048 scopus 로고    scopus 로고
    • An immunocompetent mouse model for the tolerance of human chronic hepatitis B virus infection
    • Huang, L. R., H. L. Wu, P. J. Chen, and D. S. Chen. 2006. An immunocompetent mouse model for the tolerance of human chronic hepatitis B virus infection. Proc. Natl. Acad. Sci. USA 103: 17862-17867.
    • (2006) Proc. Natl. Acad. Sci. USA , vol.103 , pp. 17862-17867
    • Huang, L.R.1    Wu, H.L.2    Chen, P.J.3    Chen, D.S.4
  • 21
    • 34548801289 scopus 로고    scopus 로고
    • Increased susceptibility to liver injury in hepatitis B virus transgenic mice involves NKG2D-ligand interaction and natural killer cells
    • Chen, Y., H. Wei, R. Sun, Z. Dong, J. Zhang, and Z. Tian. 2007. Increased susceptibility to liver injury in hepatitis B virus transgenic mice involves NKG2D-ligand interaction and natural killer cells. Hepatology 46: 706-715.
    • (2007) Hepatology , vol.46 , pp. 706-715
    • Chen, Y.1    Wei, H.2    Sun, R.3    Dong, Z.4    Zhang, J.5    Tian, Z.6
  • 22
    • 84885445313 scopus 로고    scopus 로고
    • IL-12-based vaccination therapy reverses liver-induced systemic tolerance in a mouse model of hepatitis B virus carrier
    • Zeng, Z., X. Kong, F. Li, H. Wei, R. Sun, and Z. Tian. 2013. IL-12-based vaccination therapy reverses liver-induced systemic tolerance in a mouse model of hepatitis B virus carrier. J. Immunol. 191: 4184-4193.
    • (2013) J. Immunol , vol.191 , pp. 4184-4193
    • Zeng, Z.1    Kong, X.2    Li, F.3    Wei, H.4    Sun, R.5    Tian, Z.6
  • 23
    • 84893669236 scopus 로고    scopus 로고
    • Kupffer cell-derived IL-10 plays a key role in maintaining humoral immune tolerance in hepatitis B viruspersistent mice
    • Xu, L., W. Yin, R. Sun, H. Wei, and Z. Tian. 2014. Kupffer cell-derived IL-10 plays a key role in maintaining humoral immune tolerance in hepatitis B viruspersistent mice. Hepatology 59: 443-452.
    • (2014) Hepatology , vol.59 , pp. 443-452
    • Xu, L.1    Yin, W.2    Sun, R.3    Wei, H.4    Tian, Z.5
  • 24
    • 84868702241 scopus 로고    scopus 로고
    • Innate and adaptive immune responses in chronic hepatitis B virus infections: Towards restoration of immune control of viral infection
    • Bertoletti, A., and C. Ferrari. 2012. Innate and adaptive immune responses in chronic hepatitis B virus infections: towards restoration of immune control of viral infection. Gut 61: 1754-1764.
    • (2012) Gut , vol.61 , pp. 1754-1764
    • Bertoletti, A.1    Ferrari, C.2
  • 28
    • 34548024379 scopus 로고    scopus 로고
    • Tumor-infiltrating gammadelta T cells suppress T and dendritic cell function via mechanisms controlled by a unique toll-like receptor signaling pathway
    • Peng, G., H. Y. Wang, W. Peng, Y. Kiniwa, K. H. Seo, and R. F. Wang. 2007. Tumor-infiltrating gammadelta T cells suppress T and dendritic cell function via mechanisms controlled by a unique toll-like receptor signaling pathway. Immunity 27: 334-348.
    • (2007) Immunity , vol.27 , pp. 334-348
    • Peng, G.1    Wang, H.Y.2    Peng, W.3    Kiniwa, Y.4    Seo, K.H.5    Wang, R.F.6
  • 33
    • 84900482064 scopus 로고    scopus 로고
    • GdT17 cells promote the accumulation and expansion of myeloid-derived suppressor cells in human colorectal cancer
    • Wu, P., D. Wu, C. Ni, J. Ye, W. Chen, G. Hu, Z. Wang, C. Wang, Z. Zhang, W. Xia, et al. 2014. gdT17 cells promote the accumulation and expansion of myeloid-derived suppressor cells in human colorectal cancer. Immunity 40: 785-800.
    • (2014) Immunity , vol.40 , pp. 785-800
    • Wu, P.1    Wu, D.2    Ni, C.3    Ye, J.4    Chen, W.5    Hu, G.6    Wang, Z.7    Wang, C.8    Zhang, Z.9    Xia, W.10
  • 34
    • 73449125874 scopus 로고    scopus 로고
    • Interleukin-17-producing CD4(+ T cells increase with severity of liver damage in patients with chronic hepatitis B
    • Zhang, J. Y., Z. Zhang, F. Lin, Z. S. Zou, R. N. Xu, L. Jin, J. L. Fu, F. Shi, M. Shi, H. F. Wang, and F. S. Wang. 2010. Interleukin-17-producing CD4(+) T cells increase with severity of liver damage in patients with chronic hepatitis B. Hepatology 51: 81-91.
    • (2010) Hepatology , vol.51 , pp. 81-91
    • Zhang, J.Y.1    Zhang, Z.2    Lin, F.3    Zou, Z.S.4    Xu, R.N.5    Jin, L.6    Fu, J.L.7    Shi, F.8    Shi, M.9    Wang, H.F.10    Wang, F.S.11
  • 35
    • 68649126866 scopus 로고    scopus 로고
    • Interleukin-17-producing gammadelta T cells selectively expand in response to pathogen products and environmental signals
    • Martin, B., K. Hirota, D. J. Cua, B. Stockinger, and M. Veldhoen. 2009. Interleukin-17-producing gammadelta T cells selectively expand in response to pathogen products and environmental signals. Immunity 31: 321-330.
    • (2009) Immunity , vol.31 , pp. 321-330
    • Martin, B.1    Hirota, K.2    Cua, D.J.3    Stockinger, B.4    Veldhoen, M.5
  • 36
    • 84984577973 scopus 로고    scopus 로고
    • Immunocompetent nontransgenic mouse models for studying hepatitis B virus immune responses
    • Tzeng, H. T., P. N. Hsu, and P. J. Chen. 2013. Immunocompetent nontransgenic mouse models for studying hepatitis B virus immune responses. J. Gastroenterol. Hepatol. 28(Suppl 1): 116-119.
    • (2013) J. Gastroenterol. Hepatol , vol.28 , Issue.SUPPL. 1 , pp. 116-119
    • Tzeng, H.T.1    Hsu, P.N.2    Chen, P.J.3
  • 38
    • 78649572605 scopus 로고    scopus 로고
    • Treatment of children with chronic hepatitis B virus infection in the United States: Patient selection and therapeutic options
    • Hepatitis B Foundation
    • Jonas, M. M., J. M. Block, B. A. Haber, S. J. Karpen, W. T. London, K. F. Murray, M. R. Narkewicz, P. Rosenthal, K. B. Schwarz, and B. J. McMahon, Hepatitis B Foundation. 2010. Treatment of children with chronic hepatitis B virus infection in the United States: patient selection and therapeutic options. Hepatology 52: 2192-2205.
    • (2010) Hepatology , vol.52 , pp. 2192-2205
    • Jonas, M.M.1    Block, J.M.2    Haber, B.A.3    Karpen, S.J.4    London, W.T.5    Murray, K.F.6    Narkewicz, M.R.7    Rosenthal, P.8    Schwarz, K.B.9    McMahon, B.J.10


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.