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Volumn 36, Issue 4, 2014, Pages 443-459

Immunopathology of lupus nephritis

Author keywords

Belimumab; Chronic kidney disease; Glomerulonephritis; Immune complex; Interferon; Systemic lupus erythematosus

Indexed keywords

ANTIGEN ANTIBODY COMPLEX; AUTOIMMUNITY; B LYMPHOCYTE; CELL EXPANSION; DISEASE CLASSIFICATION; DISEASE SEVERITY; ELECTRON MICROSCOPY; END STAGE RENAL DISEASE; HUMAN; IMMUNE DYSREGULATION; IMMUNOLOGICAL TOLERANCE; IMMUNOMODULATION; IMMUNOPATHOGENESIS; IMMUNOPATHOLOGY; IMMUNOREGULATION; LUPUS ERYTHEMATOSUS NEPHRITIS; NONHUMAN; PRIORITY JOURNAL; PROGNOSIS; REVIEW; T LYMPHOCYTE; IMMUNOLOGY; KIDNEY; PATHOLOGY;

EID: 84905908611     PISSN: 18632297     EISSN: 18632300     Source Type: Journal    
DOI: 10.1007/s00281-013-0413-5     Document Type: Review
Times cited : (46)

References (124)
  • 1
    • 84862016703 scopus 로고    scopus 로고
    • Taming lupus - A new understanding of pathogenesis is leading to clinical advances
    • Liu Z, Davidson A (2012) Taming lupus-a new understanding of pathogenesis is leading to clinical advances. Nat Med 18:871-882
    • (2012) Nat Med , vol.18 , pp. 871-882
    • Liu, Z.1    Davidson, A.2
  • 2
    • 82555196095 scopus 로고    scopus 로고
    • Systemic lupus erythematosus
    • Tsokos GC (2011) Systemic lupus erythematosus. N Engl J Med 365:2110-2121
    • (2011) N Engl J Med , vol.365 , pp. 2110-2121
    • Tsokos, G.C.1
  • 3
    • 0036892104 scopus 로고    scopus 로고
    • Definition of risk factors for death, end stage renal disease, and thromboembolic events in a monocentric cohort of 338 patients with systemic lupus erythematosus
    • DOI 10.1136/ard.61.12.1065
    • Manger K, Manger B, Repp R, Geisselbrecht M, Geiger A, Pfahlberg A, Harrer T, Kalden JR (2002) Definition of risk factors for death, end stage renal disease, and thromboembolic events in a monocentric cohort of 338 patients with systemic lupus erythematosus. Ann Rheum Dis 61:1065-1070 (Pubitemid 35397352)
    • (2002) Annals of the Rheumatic Diseases , vol.61 , Issue.12 , pp. 1065-1070
    • Manger, K.1    Manger, B.2    Repp, R.3    Geisselbrecht, M.4    Geiger, A.5    Pfahlberg, A.6    Harrer, T.7    Kalden, J.R.8
  • 5
    • 34447098797 scopus 로고    scopus 로고
    • Multistep pathogenesis of autoimmune disease
    • Goodnow CC (2007) Multistep pathogenesis of autoimmune disease. Cell 130:25-35
    • (2007) Cell , vol.130 , pp. 25-35
    • Goodnow, C.C.1
  • 7
    • 84857788719 scopus 로고    scopus 로고
    • A novel pathogenetic conceptantiviral immunity in lupus nephritis
    • Migliorini A, Anders HJ (2012) A novel pathogenetic conceptantiviral immunity in lupus nephritis. Nat Rev Nephrol 8:183-189
    • (2012) Nat Rev Nephrol , vol.8 , pp. 183-189
    • Migliorini, A.1    Anders, H.J.2
  • 13
    • 80052173701 scopus 로고    scopus 로고
    • Systemic lupus erythematosus and the neutrophil
    • Bosch X (2011) Systemic lupus erythematosus and the neutrophil. N Engl J Med 365:758-760
    • (2011) N Engl J Med , vol.365 , pp. 758-760
    • Bosch, X.1
  • 15
    • 67849126802 scopus 로고    scopus 로고
    • Three checkpoints in lupus development: Central tolerance in adaptive immunity, peripheral amplification by innate immunity and end-organ inflammation
    • Kanta H,Mohan C (2009) Three checkpoints in lupus development: central tolerance in adaptive immunity, peripheral amplification by innate immunity and end-organ inflammation. Genes Immun 10(5): 390-396
    • (2009) Genes Immun , vol.10 , Issue.5 , pp. 390-396
    • Kanta, H.1    Mohan, C.2
  • 17
    • 67849099131 scopus 로고    scopus 로고
    • Recent insights into the genetic basis of systemic lupus erythematosus
    • Moser KL, Kelly JA, Lessard CJ, Harley JB (2009) Recent insights into the genetic basis of systemic lupus erythematosus. Genes Immun 10:373-379
    • (2009) Genes Immun , vol.10 , pp. 373-379
    • Moser, K.L.1    Kelly, J.A.2    Lessard, C.J.3    Harley, J.B.4
  • 18
    • 84875937513 scopus 로고    scopus 로고
    • Genetic susceptibility to SLE: Recent progress from GWAS
    • Cui Y, Sheng Y, Zhang X (2013) Genetic susceptibility to SLE: recent progress from GWAS. J Autoimmun 41:25-33
    • (2013) J Autoimmun , vol.41 , pp. 25-33
    • Cui, Y.1    Sheng, Y.2    Zhang, X.3
  • 19
    • 17644402442 scopus 로고    scopus 로고
    • Type I interferons (alpha/beta) in immunity and autoimmunity
    • DOI 10.1146/annurev.immunol.23.021704.115843
    • Theofilopoulos AN, Baccala R, Beutler B, Kono DH (2005) Type I interferons (alpha/beta) in immunity and autoimmunity. Annu Rev Immunol 23:307-336 (Pubitemid 40563172)
    • (2005) Annual Review of Immunology , vol.23 , pp. 307-336
    • Theofilopoulos, A.N.1    Baccala, R.2    Beutler, B.3    Kono, D.H.4
  • 20
    • 0345016444 scopus 로고    scopus 로고
    • Ultraviolet B Radiation-Induced Cell Death: Critical Role of Ultraviolet Dose in Inflammation and Lupus Autoantigen Redistribution
    • Caricchio R, McPhie L, Cohen PL (2003) Ultraviolet B radiation-induced cell death: critical role of ultraviolet dose in inflammation and lupus autoantigen redistribution. J Immunol 171:5778-5786 (Pubitemid 37467193)
    • (2003) Journal of Immunology , vol.171 , Issue.11 , pp. 5778-5786
    • Caricchio, R.1    McPhie, L.2    Cohen, P.L.3
  • 22
    • 0025666735 scopus 로고
    • Evidence for impaired T cell DNA methylation in systemic lupus erythematosus and rheumatoid arthritis
    • Richardson B, Scheinbart L, Strahler J, Gross L, Hanash S, Johnson M (1990) Evidence for impaired T cell DNA methylation in systemic lupus erythematosus and rheumatoid arthritis. Arthritis Rheum 33:1665-1673
    • (1990) Arthritis Rheum , vol.33 , pp. 1665-1673
    • Richardson, B.1    Scheinbart, L.2    Strahler, J.3    Gross, L.4    Hanash, S.5    Johnson, M.6
  • 23
    • 84858439656 scopus 로고    scopus 로고
    • Progesterone and autoimmune disease
    • Hughes GC (2012) Progesterone and autoimmune disease. Autoimmun Rev 11:A502-A514
    • (2012) Autoimmun Rev , vol.11
    • Hughes, G.C.1
  • 26
    • 78650108453 scopus 로고    scopus 로고
    • Dendritic cells in lupus are not required for activation of T and B cells but promote their expansion, resulting in tissue damage
    • Teichmann LL, Ols ML, Kashgarian M, Reizis B, Kaplan DH, Shlomchik MJ (2010) Dendritic cells in lupus are not required for activation of T and B cells but promote their expansion, resulting in tissue damage. Immunity 33:967-978
    • (2010) Immunity , vol.33 , pp. 967-978
    • Teichmann, L.L.1    Ols, M.L.2    Kashgarian, M.3    Reizis, B.4    Kaplan, D.H.5    Shlomchik, M.J.6
  • 27
    • 42449117483 scopus 로고    scopus 로고
    • Requirement of toll-like receptor 7 for pristane-induced production of autoantibodies and development of murine lupus nephritis
    • DOI 10.1002/art.23407
    • Savarese E, Steinberg C, Pawar RD, Reindl W, Akira S, Anders HJ, Krug A (2008) Requirement of Toll-like receptor 7 for pristaneinduced production of autoantibodies and development of murine lupus nephritis. Arthritis Rheum 58:1107-1115 (Pubitemid 351564013)
    • (2008) Arthritis and Rheumatism , vol.58 , Issue.4 , pp. 1107-1115
    • Savarese, E.1    Steinberg, C.2    Pawar, R.D.3    Reindl, W.4    Akira, S.5    Anders, H.-J.6    Krug, A.7
  • 28
    • 0037061453 scopus 로고    scopus 로고
    • Chromatin-IgG complexes activate B cells by dual engagement of IgM and Toll-like receptors
    • DOI 10.1038/416603a
    • Leadbetter EA, Rifkin IR, Hohlbaum AM, Beaudette BC, Shlomchik MJ, Marshak-Rothstein A (2002) Chromatin-IgG complexes activate B cells by dual engagement of IgM and Toll-like receptors. Nature 416:603-607 (Pubitemid 34406754)
    • (2002) Nature , vol.416 , Issue.6881 , pp. 603-607
    • Leadbetter, E.A.1    Rifkin, I.R.2    Hohlbaum, A.M.3    Beaudette, B.C.4    Shlomchik, M.J.5    Marshak-Rothstein, A.6
  • 32
    • 68949181883 scopus 로고    scopus 로고
    • TIR8/SIGIRR: An IL-1R/TLR family member with regulatory functions in inflammation and T cell polarization
    • Garlanda C, Anders HJ,Mantovani A (2009) TIR8/SIGIRR: an IL-1R/TLR family member with regulatory functions in inflammation and T cell polarization. Trends Immunol 30:439-446
    • (2009) Trends Immunol , vol.30 , pp. 439-446
    • Garlanda, C.1    Anders, H.J.2    Mantovani, A.3
  • 35
    • 34249915031 scopus 로고    scopus 로고
    • Inhibition of Toll-like receptor-7 (TLR-7) or TLR-7 plus TLR-9 attenuates glomerulonephritis and lung injury in experimental lupus
    • DOI 10.1681/ASN.2006101162
    • Pawar RD, Ramanjaneyulu A, Kulkarni OP, Lech M, Segerer S, Anders HJ (2007) Inhibition of Toll-like receptor-7 (TLR-7) or TLR-7 plus TLR-9 attenuates glomerulonephritis and lung injury in experimental lupus. J Am Soc Nephrol 18:1721-1731 (Pubitemid 46870309)
    • (2007) Journal of the American Society of Nephrology , vol.18 , Issue.6 , pp. 1721-1731
    • Pawar, R.D.1    Ramanjaneyulu, A.2    Kulkarni, O.P.3    Lech, M.4    Segerer, S.5    Anders, H.-J.6
  • 36
    • 70749096596 scopus 로고    scopus 로고
    • Pseudoviral immunity - A novel concept for lupus
    • Anders HJ (2009) Pseudoviral immunity-a novel concept for lupus. Trends Mol Med 15:553-561
    • (2009) Trends Mol Med , vol.15 , pp. 553-561
    • Anders, H.J.1
  • 37
    • 34247891509 scopus 로고    scopus 로고
    • Immunologically active autoantigens: The role of toll-like receptors in the development of chronic inflammatory disease
    • Marshak-Rothstein A, Rifkin IR (2007) Immunologically active autoantigens: the role of toll-like receptors in the development of chronic inflammatory disease. Annu Rev Immunol 25:419- 441
    • (2007) Annu Rev Immunol , vol.25 , pp. 419-441
    • Marshak-Rothstein, A.1    Rifkin, I.R.2
  • 38
    • 0033577903 scopus 로고    scopus 로고
    • A novel mouse with B cells but lacking serum antibody reveals an antibody-independent role for B cells in murine lupus
    • Chan OT, Hannum LG, Haberman AM, Madaio MP, Shlomchik MJ (1999) A novel mouse with B cells but lacking serum antibody reveals an antibody-independent role for B cells in murine lupus. J Exp Med 189:1639-1648
    • (1999) J Exp Med , vol.189 , pp. 1639-1648
    • Chan, O.T.1    Hannum, L.G.2    Haberman, A.M.3    Madaio, M.P.4    Shlomchik, M.J.5
  • 39
    • 84865721122 scopus 로고    scopus 로고
    • Endogenous antigen tunes the responsiveness of naive B cells but not T cells
    • Zikherman J, Parameswaran R, Weiss A (2012) Endogenous antigen tunes the responsiveness of naive B cells but not T cells. Nature 489:160-164
    • (2012) Nature , vol.489 , pp. 160-164
    • Zikherman, J.1    Parameswaran, R.2    Weiss, A.3
  • 40
    • 80555146731 scopus 로고    scopus 로고
    • Murine double minute-2 drives systemic lupus erythematosus and lupus nephritis
    • in press
    • Allam R, Sayyed SG, Kulkarni O, Lichtnekert J, Anders HJ (2011) Murine double minute-2 drives systemic lupus erythematosus and lupus nephritis. J Am Soc Nephrol 22:2016-2027, in press
    • (2011) J Am Soc Nephrol , vol.22 , pp. 2016-2027
    • Allam, R.1    Sayyed, S.G.2    Kulkarni, O.3    Lichtnekert, J.4    Anders, H.J.5
  • 41
    • 79960918034 scopus 로고    scopus 로고
    • BAFF and selection of autoreactive B cells
    • Liu Z, Davidson A (2011) BAFF and selection of autoreactive B cells. Trends Immunol 32:388-394
    • (2011) Trends Immunol , vol.32 , pp. 388-394
    • Liu, Z.1    Davidson, A.2
  • 42
    • 78650317840 scopus 로고    scopus 로고
    • Novel treatments for systemic lupus erythematosus
    • Gayed M, Gordon C (2010) Novel treatments for systemic lupus erythematosus. Curr Opin Investig Drugs 11:1256- 1264
    • (2010) Curr Opin Investig Drugs , vol.11 , pp. 1256-1264
    • Gayed, M.1    Gordon, C.2
  • 45
    • 42949136582 scopus 로고    scopus 로고
    • The prognosis and pathogenesis of severe lupus glomerulonephritis
    • DOI 10.1093/ndt/gfm775
    • Schwartz MM, Korbet SM, Lewis EJ (2008) The prognosis and pathogenesis of severe lupus glomerulonephritis. Nephrol Dial Transplant 23:1298-1306 (Pubitemid 351767497)
    • (2008) Nephrology Dialysis Transplantation , vol.23 , Issue.4 , pp. 1298-1306
    • Schwartz, M.M.1    Korbet, S.M.2    Lewis, E.J.3
  • 47
    • 0035188299 scopus 로고    scopus 로고
    • Predictive power of the second renal biopsy in lupus nephritis: Significance of macrophages
    • Hill GS, Delahousse M, Nochy D, Remy P, Mignon F, Mery JP, Bariety J (2001) Predictive power of the second renal biopsy in lupus nephritis: significance of macrophages. Kidney Int 59:304- 316
    • (2001) Kidney Int , vol.59 , pp. 304-316
    • Hill, G.S.1    Delahousse, M.2    Nochy, D.3    Remy, P.4    Mignon, F.5    Mery, J.P.6    Bariety, J.7
  • 52
    • 33644785974 scopus 로고    scopus 로고
    • Association of glomerular podocytopathy and nephrotic proteinuria in mesangial lupus nephritis
    • DOI 10.1191/0961203306lu2264oa
    • Han TS, Schwartz MM, Lewis EJ (2006) Association of glomerular podocytopathy and nephrotic proteinuria inmesangial lupus nephritis. Lupus 15:71-75 (Pubitemid 43345330)
    • (2006) Lupus , vol.15 , Issue.2 , pp. 71-75
    • Han, T.S.1    Schwartz, M.M.2    Lewis, E.J.3
  • 55
    • 0023001705 scopus 로고
    • Tubulointerstitial disease in lupus nephritis: Relationship to immune deposits, interstitial inflammation, glomerular changes, renal function, and prognosis
    • Park MH, D'Agati V, Appel GB, Pirani CL (1986) Tubulointerstitial disease in lupus nephritis: relationship to immune deposits, interstitial inflammation, glomerular changes, renal function, and prognosis. Nephron 44:309-319 (Pubitemid 17178104)
    • (1986) Nephron , vol.44 , Issue.4 , pp. 309-319
    • Park, M.H.1    D'Agati, V.2    Appel, G.B.3    Pirani, C.L.4
  • 56
    • 0026769228 scopus 로고
    • Tubulointerstitial changes as a major determinant in the progression of renal damage
    • Nath KA (1992) Tubulointerstitial changes as a major determinant in the progression of renal damage. Am J Kidney Dis 20:1-17
    • (1992) Am J Kidney Dis , vol.20 , pp. 1-17
    • Nath, K.A.1
  • 57
    • 33745495804 scopus 로고    scopus 로고
    • Tubulointerstitial immune complex nephritis in a patient with systemic lupus erythematosus: Role of peritubular capillaritis with immune complex deposits in the pathogenesis of the tubulointerstitial nephritis
    • DOI 10.1007/s10157-006-0405-z
    • Hayakawa S, Nakabayashi K, Karube M, Arimura Y, Soejima A, Yamada A, Fujioka Y (2006) Tubulointerstitial immune complex nephritis in a patient with systemic lupus erythematosus: role of peritubular capillaritis with immune complex deposits in the pathogenesis of the tubulointerstitial nephritis. Clin Exp Nephrol 10: 146-151 (Pubitemid 43961610)
    • (2006) Clinical and Experimental Nephrology , vol.10 , Issue.2 , pp. 146-151
    • Hayakawa, S.1    Nakabayashi, K.2    Karube, M.3    Arimura, Y.4    Soejima, A.5    Yamada, A.6    Fujioka, Y.7
  • 58
    • 84055182927 scopus 로고    scopus 로고
    • Mechanisms of tissue injury in lupus nephritis
    • Nowling TK, Gilkeson GS (2011) Mechanisms of tissue injury in lupus nephritis. Arthritis Res Ther 13:250
    • (2011) Arthritis Res Ther , vol.13 , pp. 250
    • Nowling, T.K.1    Gilkeson, G.S.2
  • 59
    • 84863664311 scopus 로고    scopus 로고
    • Autoantibodies and resident renal cells in the pathogenesis of lupus nephritis-getting to know the unknown
    • Yung S, Chan TM(2012) Autoantibodies and resident renal cells in the pathogenesis of lupus nephritis-getting to know the unknown. Clin Dev Immunol 2012:139365
    • (2012) Clin Dev Immunol , vol.2012 , pp. 139365
    • Yung, S.1    Chan, T.M.2
  • 60
    • 65249171440 scopus 로고    scopus 로고
    • Nephritogenic potential of anti-DNA antibodies against necrotic nucleosomes
    • Mortensen ES, Rekvig OP (2009) Nephritogenic potential of anti-DNA antibodies against necrotic nucleosomes. J Am Soc Nephrol 20:696-704
    • (2009) J Am Soc Nephrol , vol.20 , pp. 696-704
    • Mortensen, E.S.1    Rekvig, O.P.2
  • 61
    • 78149305875 scopus 로고    scopus 로고
    • Anti-dsDNA antibodies bind to mesangial annexin II in lupus nephritis
    • Yung S, Cheung KF, Zhang Q, Chan TM (2010) Anti-dsDNA antibodies bind to mesangial annexin II in lupus nephritis. J Am Soc Nephrol 21:1912-1927
    • (2010) J Am Soc Nephrol , vol.21 , pp. 1912-1927
    • Yung, S.1    Cheung, K.F.2    Zhang, Q.3    Chan, T.M.4
  • 62
    • 33744924742 scopus 로고    scopus 로고
    • Differential binding of cross-reactive anti-DNA antibodies to mesangial cells: The role of alpha-actinin
    • Zhao Z, Deocharan B, Scherer PE, Ozelius LJ, Putterman C (2006) Differential binding of cross-reactive anti-DNA antibodies to mesangial cells: the role of alpha-actinin. J Immunol 176:7704- 7714
    • (2006) J Immunol , vol.176 , pp. 7704-7714
    • Zhao, Z.1    Deocharan, B.2    Scherer, P.E.3    Ozelius, L.J.4    Putterman, C.5
  • 63
    • 79960143926 scopus 로고    scopus 로고
    • Nephritogenic antibodies bind in glomeruli through interaction with exposed chromatin fragments and not with renal cross-reactive antigens
    • Mjelle JE, Rekvig OP, Van Der Vlag J, Fenton KA (2011) Nephritogenic antibodies bind in glomeruli through interaction with exposed chromatin fragments and not with renal cross-reactive antigens. Autoimmunity 44:373-383
    • (2011) Autoimmunity , vol.44 , pp. 373-383
    • Mjelle, J.E.1    Rekvig, O.P.2    Van Der Vlag, J.3    Fenton, K.A.4
  • 64
    • 77649325116 scopus 로고    scopus 로고
    • Pure anti-dsDNA mAbs need chromatin structures to promote glomerular mesangial deposits in BALB/c mice
    • Fenton KA, Tommeras B, Marion TN, Rekvig OP (2010) Pure anti-dsDNA mAbs need chromatin structures to promote glomerular mesangial deposits in BALB/c mice. Autoimmunity 43:179-188
    • (2010) Autoimmunity , vol.43 , pp. 179-188
    • Fenton, K.A.1    Tommeras, B.2    Marion, T.N.3    Rekvig, O.P.4
  • 66
    • 31144472862 scopus 로고    scopus 로고
    • Intravenous immunoglobulin for immunomodulation of systemic lupus erythematosus
    • DOI 10.1016/j.autrev.2005.09.002, PII S1568997205001540
    • Sherer Y, Shoenfeld Y (2006) Intravenous immunoglobulin for immunomodulation of systemic lupus erythematosus. Autoimmun Rev 5:153-155 (Pubitemid 43129550)
    • (2006) Autoimmunity Reviews , vol.5 , Issue.2 SPEC. ISS. , pp. 153-155
    • Sherer, Y.1    Shoenfeld, Y.2
  • 67
    • 69849111830 scopus 로고    scopus 로고
    • Viral RNA and DNA sense common antiviral responses including type I interferons in mesangial cells
    • in press
    • Allam R, Lichtnekert J,Moll A, Taubitz A, Vielhauer V, Anders HJ (2009) Viral RNA and DNA sense common antiviral responses including type I interferons in mesangial cells. J Am Soc Nephrol 20:1986-1996, in press
    • (2009) J Am Soc Nephrol , vol.20 , pp. 1986-1996
    • Allam, R.1    Lichtnekert, J.2    Moll, A.3    Taubitz, A.4    Vielhauer, V.5    Anders, H.J.6
  • 68
    • 73649090376 scopus 로고    scopus 로고
    • Viral RNA induces type I interferon-dependent cytokine release and cell death in mesangial cells via MDA5. Implications for viral infection-associated glomerulonephritis
    • in press
    • Fluer K, Allam R, Zecher D, Kulkarni O, Lichtnekert J, Schwarz M, Beutler B, Vielhauer V, Anders HJ (2009) Viral RNA induces type I interferon-dependent cytokine release and cell death in mesangial cells via MDA5. Implications for viral infection-associated glomerulonephritis. Am J Pathol 175:2014-2022, in press
    • (2009) Am J Pathol , vol.175 , pp. 2014-2022
    • Fluer, K.1    Allam, R.2    Zecher, D.3    Kulkarni, O.4    Lichtnekert, J.5    Schwarz, M.6    Beutler, B.7    Vielhauer, V.8    Anders, H.J.9
  • 69
    • 70749116345 scopus 로고    scopus 로고
    • Double-stranded RNA activates type I interferon secretion in glomerular endothelial cells via retinoic acid-inducible gene (RIG)-1
    • Hagele H, Allam R, Pawar RD, Anders HJ (2009) Double-stranded RNA activates type I interferon secretion in glomerular endothelial cells via retinoic acid-inducible gene (RIG)-1. Nephrol Dial Transplant 24:3312-3318
    • (2009) Nephrol Dial Transplant , vol.24 , pp. 3312-3318
    • Hagele, H.1    Allam, R.2    Pawar, R.D.3    Anders, H.J.4
  • 70
    • 73649094099 scopus 로고    scopus 로고
    • Double-stranded DNA activates glomerular endothelial cells and enhances albumin permeability via a toll-like receptorindependent cytosolic DNA recognition pathway
    • Hagele H, Allam R, Pawar RD, Reichel CA, Krombach F, Anders HJ (2009) Double-stranded DNA activates glomerular endothelial cells and enhances albumin permeability via a toll-like receptorindependent cytosolic DNA recognition pathway. Am J Pathol 175: 1896-1904
    • (2009) Am J Pathol , vol.175 , pp. 1896-1904
    • Hagele, H.1    Allam, R.2    Pawar, R.D.3    Reichel, C.A.4    Krombach, F.5    Anders, H.J.6
  • 72
    • 77951856955 scopus 로고    scopus 로고
    • Interferon-alpha and - beta in kidney inflammation
    • Anders HJ, Lichtnekert J, Allam R (2010) Interferon-alpha and - beta in kidney inflammation. Kidney Int 77:848-854
    • (2010) Kidney Int , vol.77 , pp. 848-854
    • Anders, H.J.1    Lichtnekert, J.2    Allam, R.3
  • 75
    • 84876803671 scopus 로고    scopus 로고
    • Nucleosomes contribute to increase mesangial cell chemokine expression during the development of lupus nephritis
    • Kanapathippillai P, Hedberg A, Fenton CG, Fenton KA (2013) Nucleosomes contribute to increase mesangial cell chemokine expression during the development of lupus nephritis. Cytokine 62: 244-252
    • (2013) Cytokine , vol.62 , pp. 244-252
    • Kanapathippillai, P.1    Hedberg, A.2    Fenton, C.G.3    Fenton, K.A.4
  • 76
    • 0014435184 scopus 로고
    • Lupus nephritis: Varying complement-fixing properties of immunoglobulin G antibodies to antigens of cell nuclei
    • Tojo T, Friou GJ (1968) Lupus nephritis: varying complement-fixing properties of immunoglobulin G antibodies to antigens of cell nuclei. Science 161:904-906
    • (1968) Science , vol.161 , pp. 904-906
    • Tojo, T.1    Friou, G.J.2
  • 77
    • 79953729061 scopus 로고    scopus 로고
    • The benefit of targeted and selective inhibition of the alternative complement pathway for modulating autoimmunity and renal disease in MRL/lpr mice
    • Sekine H, Kinser TT, Qiao F, Martinez E, Paulling E, Ruiz P, Gilkeson GS, Tomlinson S (2011) The benefit of targeted and selective inhibition of the alternative complement pathway for modulating autoimmunity and renal disease in MRL/lpr mice. Arthritis Rheum 63:1076-1085
    • (2011) Arthritis Rheum , vol.63 , pp. 1076-1085
    • Sekine, H.1    Kinser, T.T.2    Qiao, F.3    Martinez, E.4    Paulling, E.5    Ruiz, P.6    Gilkeson, G.S.7    Tomlinson, S.8
  • 78
    • 79551664780 scopus 로고    scopus 로고
    • Complement factor H deficiency accelerates development of lupus nephritis
    • Bao L, Haas M, Quigg RJ (2011) Complement factor H deficiency accelerates development of lupus nephritis. J Am Soc Nephrol 22: 285-295
    • (2011) J Am Soc Nephrol , vol.22 , pp. 285-295
    • Bao, L.1    Haas, M.2    Quigg, R.J.3
  • 79
    • 0030752624 scopus 로고    scopus 로고
    • Extraglomerular origin of the mesangial cell after injury. A new role of the juxtaglomerular apparatus
    • Hugo C, Shankland SJ, Bowen-Pope DF, Couser WG, Johnson RJ (1997) Extraglomerular origin of the mesangial cell after injury. A new role of the juxtaglomerular apparatus. J Clin Invest 100:786- 794
    • (1997) J Clin Invest , vol.100 , pp. 786-794
    • Hugo, C.1    Shankland, S.J.2    Bowen-Pope, D.F.3    Couser, W.G.4    Johnson, R.J.5
  • 80
    • 84877941083 scopus 로고    scopus 로고
    • The danger control concept in kidney disease: Mesangial cells
    • Migliorini A, Ebid R, Scherbaum CR, Anders HJ (2013) The danger control concept in kidney disease: mesangial cells. J Nephrol 26:437-449
    • (2013) J Nephrol , vol.26 , pp. 437-449
    • Migliorini, A.1    Ebid, R.2    Scherbaum, C.R.3    Anders, H.J.4
  • 81
    • 79952421724 scopus 로고    scopus 로고
    • Heparin exerts a dual effect on murine lupus nephritis by enhancing enzymatic chromatin degradation and preventing chromatin binding in glomerular membranes
    • Hedberg A, Fismen S, Fenton KA, Fenton C, Osterud B,Mortensen ES, Rekvig OP (2011) Heparin exerts a dual effect on murine lupus nephritis by enhancing enzymatic chromatin degradation and preventing chromatin binding in glomerular membranes. Arthritis Rheum 63:1065-1075
    • (2011) Arthritis Rheum , vol.63 , pp. 1065-1075
    • Hedberg, A.1    Fismen, S.2    Fenton, K.A.3    Fenton, C.4    Osterud, B.5    Mortensen, E.S.6    Rekvig, O.P.7
  • 82
    • 0019861388 scopus 로고
    • Human lupus inclusions and interferon
    • Rich SA (1981) Human lupus inclusions and interferon. Science 213:772-775
    • (1981) Science , vol.213 , pp. 772-775
    • Rich, S.A.1
  • 84
    • 33746731651 scopus 로고    scopus 로고
    • HMGB1 signals through toll-like receptor (TLR) 4 and TLR2
    • DOI 10.1097/01.shk.0000225404.51320.82, PII 0002438220060800000011
    • Yu M, Wang H, Ding A, Golenbock DT, Latz E, Czura CJ, Fenton MJ, Tracey KJ, Yang H (2006) HMGB1 signals through toll-like receptor (TLR) 4 and TLR2. Shock 26:174-179 (Pubitemid 44162504)
    • (2006) Shock , vol.26 , Issue.2 , pp. 174-179
    • Yu, M.1    Wang, H.2    Ding, A.3    Golenbock, D.T.4    Latz, E.5    Czura, C.J.6    Fenton, M.J.7    Tracey, K.J.8    Yang, H.9
  • 87
    • 42649096582 scopus 로고    scopus 로고
    • Chemokines in lupus nephritis
    • DOI 10.2741/2927
    • Kulkarni O, Anders HJ (2008) Chemokines in lupus nephritis. Front Biosci 13:3312-3320 (Pubitemid 351594684)
    • (2008) Frontiers in Bioscience , vol.13 , Issue.9 , pp. 3312-3320
    • Kulkarni, O.1    Anders, H.-J.2
  • 91
    • 0037307924 scopus 로고    scopus 로고
    • The long pentraxin PTX3 is synthesized in IgA glomerulonephritis and activates mesangial cells
    • Bussolati B, Peri G, Salvidio G, Verzola D, Mantovani A, Camussi G (2003) The long pentraxin PTX3 is synthesized in IgA glomerulonephritis and activates mesangial cells. J Immunol 170:1466- 1472
    • (2003) J Immunol , vol.170 , pp. 1466-1472
    • Bussolati, B.1    Peri, G.2    Salvidio, G.3    Verzola, D.4    Mantovani, A.5    Camussi, G.6
  • 94
    • 84874788168 scopus 로고    scopus 로고
    • Early differentiated CD138(high) MHCII+ IgG+ plasma cells express CXCR3 and localize into inflamed kidneys of lupus mice
    • Lacotte S, Decossas M, Le Coz C, Brun S, Muller S, Dumortier H (2013) Early differentiated CD138(high) MHCII+ IgG+ plasma cells express CXCR3 and localize into inflamed kidneys of lupus mice. PLoS One 8:e58140
    • (2013) PLoS One , vol.8
    • Lacotte, S.1    Decossas, M.2    Le Coz, C.3    Brun, S.4    Muller, S.5    Dumortier, H.6
  • 99
    • 77951739752 scopus 로고    scopus 로고
    • Selective blockade of BAFF for the prevention and treatment of systemic lupus erythematosus nephritis in NZM2410 mice
    • Ramanujam M, Bethunaickan R, Huang W, Tao H, Madaio MP, Davidson A (2010) Selective blockade of BAFF for the prevention and treatment of systemic lupus erythematosus nephritis in NZM2410 mice. Arthritis Rheum 62:1457-1468
    • (2010) Arthritis Rheum , vol.62 , pp. 1457-1468
    • Ramanujam, M.1    Bethunaickan, R.2    Huang, W.3    Tao, H.4    Madaio, M.P.5    Davidson, A.6
  • 101
    • 77953123031 scopus 로고    scopus 로고
    • The pathophysiologic role of monocytes and macrophages in systemic lupus erythematosus: A reappraisal
    • Katsiari CG, Liossis SN, Sfikakis PP (2010) The pathophysiologic role of monocytes and macrophages in systemic lupus erythematosus: a reappraisal. Semin Arthritis Rheum 39:491-503
    • (2010) Semin Arthritis Rheum , vol.39 , pp. 491-503
    • Katsiari, C.G.1    Liossis, S.N.2    Sfikakis, P.P.3
  • 102
    • 79953323051 scopus 로고    scopus 로고
    • IL-17-producing T cells in lupus nephritis
    • Apostolidis SA, Crispin JC, Tsokos GC (2011) IL-17-producing T cells in lupus nephritis. Lupus 20:120-124
    • (2011) Lupus , vol.20 , pp. 120-124
    • Apostolidis, S.A.1    Crispin, J.C.2    Tsokos, G.C.3
  • 104
    • 84866144185 scopus 로고    scopus 로고
    • CXCR3 promotes the production of IgG1 autoantibodies but is not essential for the development of lupus nephritis in NZB/NZW mice
    • Moser K, Kalies K, Szyska M, Humrich JY, Amann K, Manz RA (2012) CXCR3 promotes the production of IgG1 autoantibodies but is not essential for the development of lupus nephritis in NZB/NZW mice. Arthritis Rheum 64:1237-1246
    • (2012) Arthritis Rheum , vol.64 , pp. 1237-1246
    • Moser, K.1    Kalies, K.2    Szyska, M.3    Humrich, J.Y.4    Amann, K.5    Manz, R.A.6
  • 105
    • 84871256661 scopus 로고    scopus 로고
    • Plasma leakage through glomerular basement membrane ruptures triggers the proliferation of parietal epithelial cells and crescent formation in non-inflammatory glomerular injury
    • doi:10.1002/path.4046
    • Ryu M, Migliorini A, Miosge N, Gross O, Shankland S, Brinkkoetter PT, Hagmann H, Romagnani P, Liapis H, Anders HJ (2014) Plasma leakage through glomerular basement membrane ruptures triggers the proliferation of parietal epithelial cells and crescent formation in non-inflammatory glomerular injury. J Pathol. doi:10.1002/path.4046
    • (2014) J Pathol
    • Ryu, M.1    Migliorini, A.2    Miosge, N.3    Gross, O.4    Shankland, S.5    Brinkkoetter, P.T.6    Hagmann, H.7    Romagnani, P.8    Liapis, H.9    Anders, H.J.10
  • 109
    • 67651093947 scopus 로고    scopus 로고
    • Clinicopathological characteristics and outcomes of patients with crescentic lupus nephritis
    • Yu F, Tan Y, Liu G, Wang SX, Zou WZ, Zhao MH (2009) Clinicopathological characteristics and outcomes of patients with crescentic lupus nephritis. Kidney Int 76:307-317
    • (2009) Kidney Int , vol.76 , pp. 307-317
    • Yu, F.1    Tan, Y.2    Liu, G.3    Wang, S.X.4    Zou, W.Z.5    Zhao, M.H.6
  • 110
    • 0021591041 scopus 로고
    • Scanning electron microscopy of acellular glomeruli in human glomerulonephritis: Application of a technique
    • Bonsib SM (1984) Scanning electron microscopy of acellular glomeruli in human glomerulonephritis: application of a technique. Ultrastruct Pathol 7:215-217
    • (1984) Ultrastruct Pathol , vol.7 , pp. 215-217
    • Bonsib, S.M.1
  • 112
    • 0032775677 scopus 로고    scopus 로고
    • Complement (C5b-9) induces glomerular epithelial cell DNA synthesis but not proliferation in vitro
    • DOI 10.1046/j.1523-1755.1999.00560.x
    • Shankland SJ, Pippin JW, CouserWG (1999) Complement (C5b-9) induces glomerular epithelial cell DNA synthesis but not proliferation in vitro. Kidney Int 56:538-548 (Pubitemid 29353152)
    • (1999) Kidney International , vol.56 , Issue.2 , pp. 538-548
    • Shankland, S.J.1    Pippin, J.W.2    Couser, W.G.3
  • 113
    • 84886681074 scopus 로고    scopus 로고
    • New insights into the pathology of podocyte loss: Mitotic catastrophe
    • Liapis H, Romagnani P, Anders HJ (2013) New insights into the pathology of podocyte loss: mitotic catastrophe. Am J Pathol 183(5):1364-1374
    • (2013) Am J Pathol , vol.183 , Issue.5 , pp. 1364-1374
    • Liapis, H.1    Romagnani, P.2    Anders, H.J.3
  • 118
    • 77952561383 scopus 로고    scopus 로고
    • Glomerular epithelial stem cells: The good, the bad, and the ugly
    • Lasagni L, Romagnani P (2010) Glomerular epithelial stem cells: the good, the bad, and the ugly. J Am Soc Nephrol 21:1612-1619
    • (2010) J Am Soc Nephrol , vol.21 , pp. 1612-1619
    • Lasagni, L.1    Romagnani, P.2
  • 120
    • 82755197606 scopus 로고    scopus 로고
    • Tumour necrosis factor-alpha drives Alport glomerulosclerosis in mice by promoting podocyte apoptosis
    • Ryu M, Mulay SR, Miosge N, Gross O, Anders HJ (2012) Tumour necrosis factor-alpha drives Alport glomerulosclerosis in mice by promoting podocyte apoptosis. J Pathol 226:120-131
    • (2012) J Pathol , vol.226 , pp. 120-131
    • Ryu, M.1    Mulay, S.R.2    Miosge, N.3    Gross, O.4    Anders, H.J.5
  • 123
    • 84863844497 scopus 로고    scopus 로고
    • Four danger response programs determine glomerular and tubulointerstitial kidney pathology: Clotting, inflammation, epithelial and mesenchymal healing
    • Anders HJ (2012) Four danger response programs determine glomerular and tubulointerstitial kidney pathology: clotting, inflammation, epithelial and mesenchymal healing. Organogenesis 8:29-40
    • (2012) Organogenesis , vol.8 , pp. 29-40
    • Anders, H.J.1
  • 124


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