메뉴 건너뛰기




Volumn 10, Issue 5, 2009, Pages 390-396

Three checkpoints in lupus development: Central tolerance in adaptive immunity, peripheral amplification by innate immunity and end-organ inflammation

Author keywords

[No Author keywords available]

Indexed keywords

B LYMPHOCYTE RECEPTOR; CD150 ANTIGEN; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 12; INTERLEUKIN 1BETA; KALLIKREIN; TUMOR NECROSIS FACTOR ALPHA;

EID: 67849126802     PISSN: 14664879     EISSN: 14765470     Source Type: Journal    
DOI: 10.1038/gene.2009.6     Document Type: Review
Times cited : (43)

References (86)
  • 3
    • 7044223152 scopus 로고    scopus 로고
    • Genetics of human systemic lupus erythematosus: The emerging picture
    • Nath SK, Kilpatrick J, Harley JB. Genetics of human systemic lupus erythematosus: The emerging picture. Curr Opin Immunol 2004; 16 794-800.
    • (2004) Curr Opin Immunol , vol.16 , pp. 794-800
    • Nath, S.K.1    Kilpatrick, J.2    Harley, J.B.3
  • 4
    • 0034816964 scopus 로고    scopus 로고
    • Delineating the genetic basis of systemic lupus erythematosus
    • Wakeland EK, Liu K, Graham RR, Behrens TW. Delineating the genetic basis of systemic lupus erythematosus. Immunity 2001; 15: 397-408.
    • (2001) Immunity , vol.15 , pp. 397-408
    • Wakeland, E.K.1    Liu, K.2    Graham, R.R.3    Behrens, T.W.4
  • 5
    • 0027230775 scopus 로고
    • Differences in expression of lupus nephritis in New Zealand mixed H-2z homozygous inbred strains of mice derived from New Zealand black and New Zealand white mice. Origins and initial characterization
    • Rudofsky UH, Evans BD, Balaban SL, Mottironi VD, Gabrielsen AE. Differences in expression of lupus nephritis in New Zealand mixed H-2z homozygous inbred strains of mice derived from New Zealand black and New Zealand white mice. Origins and initial characterization. Lab Invest 1993; 68: 419-426.
    • (1993) Lab Invest , vol.68 , pp. 419-426
    • Rudofsky, U.H.1    Evans, B.D.2    Balaban, S.L.3    Mottironi, V.D.4    Gabrielsen, A.E.5
  • 7
    • 0030140063 scopus 로고    scopus 로고
    • Production of congenic mouse strains carrying genomic intervals containing SLE-susceptibility genes derived from the SLE-prone NZM2410 strain
    • Morel L, Yu Y, Blenman KR, Caldwell RA, Wakeland EK. Production of congenic mouse strains carrying genomic intervals containing SLE-susceptibility genes derived from the SLE-prone NZM2410 strain. Mamm Genome 1996; 7: 335-339.
    • (1996) Mamm Genome , vol.7 , pp. 335-339
    • Morel, L.1    Yu, Y.2    Blenman, K.R.3    Caldwell, R.A.4    Wakeland, E.K.5
  • 8
    • 0031570375 scopus 로고    scopus 로고
    • Functional dissection of systemic lupus erythematosus using congenic mouse strains
    • Morel L, Mohan C, Yu Y, Croker BP, Tian N, Deng A et al. Functional dissection of systemic lupus erythematosus using congenic mouse strains. J Immunol 1997; 158: 6019-6028.
    • (1997) J Immunol , vol.158 , pp. 6019-6028
    • Morel, L.1    Mohan, C.2    Yu, Y.3    Croker, B.P.4    Tian, N.5    Deng, A.6
  • 9
    • 0032520923 scopus 로고    scopus 로고
    • Genetic dissection of SLE pathogenesis. Sle1 on murine chromosome 1 leads to a selective loss of tolerance to H2A/H2B/DNA subnucleosomes
    • Mohan C, Alas E, Morel L, Yang P, Wakeland EK. Genetic dissection of SLE pathogenesis. Sle1 on murine chromosome 1 leads to a selective loss of tolerance to H2A/H2B/DNA subnucleosomes. J Clin Invest 1998; 101: 1362-1372.
    • (1998) J Clin Invest , vol.101 , pp. 1362-1372
    • Mohan, C.1    Alas, E.2    Morel, L.3    Yang, P.4    Wakeland, E.K.5
  • 10
    • 0033557753 scopus 로고    scopus 로고
    • Genetic dissection of SLE pathogenesis: Adoptive transfer of Sle1 mediates the loss of tolerance by bone marrow-derived B cells
    • Sobel ES, Mohan C, Morel L, Schiffenbauer J, Wakeland EK. Genetic dissection of SLE pathogenesis: Adoptive transfer of Sle1 mediates the loss of tolerance by bone marrow-derived B cells. J Immunol 1999; 162: 2415-2421.
    • (1999) J Immunol , vol.162 , pp. 2415-2421
    • Sobel, E.S.1    Mohan, C.2    Morel, L.3    Schiffenbauer, J.4    Wakeland, E.K.5
  • 11
    • 0031179651 scopus 로고    scopus 로고
    • Genetic dissection of systemic lupus erythematosus pathogenesis: Sle2 on murine chromosome 4 leads to B cell hyperactivity
    • Mohan C, Morel L, Yang P, Wakeland EK. Genetic dissection of systemic lupus erythematosus pathogenesis: Sle2 on murine chromosome 4 leads to B cell hyperactivity. J Immunol 1997; 159: 454-465.
    • (1997) J Immunol , vol.159 , pp. 454-465
    • Mohan, C.1    Morel, L.2    Yang, P.3    Wakeland, E.K.4
  • 12
    • 0031657151 scopus 로고    scopus 로고
    • Accumulation of splenic B1a cells with potent antigen-presenting capability in NZM2410 lupus-prone mice
    • Mohan C, Morel L, Yang P, Wakeland EK. Accumulation of splenic B1a cells with potent antigen-presenting capability in NZM2410 lupus-prone mice. Arthritis Rheum 1998; 41: 1652-1662.
    • (1998) Arthritis Rheum , vol.41 , pp. 1652-1662
    • Mohan, C.1    Morel, L.2    Yang, P.3    Wakeland, E.K.4
  • 13
    • 8444240378 scopus 로고    scopus 로고
    • Genetic dissection of the murine lupus susceptibility locus Sle2: Contributions to increased peritoneal B-1a cells and lupus nephritis map to different loci
    • Xu Z, Duan B, Croker BP, Wakeland EK, Morel L. Genetic dissection of the murine lupus susceptibility locus Sle2: Contributions to increased peritoneal B-1a cells and lupus nephritis map to different loci. J Immunol 2004; 173: 6050-6058.
    • (2004) J Immunol , vol.173 , pp. 6050-6058
    • Xu, Z.1    Duan, B.2    Croker, B.P.3    Wakeland, E.K.4    Morel, L.5
  • 14
    • 0033151971 scopus 로고    scopus 로고
    • Genetic dissection of SLE pathogenesis: Sle3 on murine chromosome 7 impacts T cell activation, differentiation, and cell death
    • Mohan C, Yu Y, Morel L, Yang P, Wakeland EK. Genetic dissection of SLE pathogenesis: Sle3 on murine chromosome 7 impacts T cell activation, differentiation, and cell death. J Immunol 1999; 162: 6492-6502.
    • (1999) J Immunol , vol.162 , pp. 6492-6502
    • Mohan, C.1    Yu, Y.2    Morel, L.3    Yang, P.4    Wakeland, E.K.5
  • 15
    • 0036785632 scopus 로고    scopus 로고
    • Genetic dissection of systemic lupus erythematosus pathogenesis: Evidence for functional expression of Sle3/5 by non-T cells
    • Sobel ES, Morel L, Baert R, Mohan C, Schiffenbauer J, Wakeland EK. Genetic dissection of systemic lupus erythematosus pathogenesis: evidence for functional expression of Sle3/5 by non-T cells. J Immunol 2002; 169: 4025-4032.
    • (2002) J Immunol , vol.169 , pp. 4025-4032
    • Sobel, E.S.1    Morel, L.2    Baert, R.3    Mohan, C.4    Schiffenbauer, J.5    Wakeland, E.K.6
  • 16
    • 0032743793 scopus 로고    scopus 로고
    • Genetic dissection of lupus pathogenesis: A recipe for nephrophilic autoantibodies
    • Mohan C, Morel L, Yang P, Watanabe H, Croker B, Gilkeson G et al. Genetic dissection of lupus pathogenesis: A recipe for nephrophilic autoantibodies. J Clin Invest 1999; 103: 1685-1695.
    • (1999) J Clin Invest , vol.103 , pp. 1685-1695
    • Mohan, C.1    Morel, L.2    Yang, P.3    Watanabe, H.4    Croker, B.5    Gilkeson, G.6
  • 17
    • 0034612320 scopus 로고    scopus 로고
    • Genetic reconstitution of systemic lupus erythematosus immunopathology with polycongenic murine strains
    • Morel L, Croker BP, Blenman KR, Mohan C, Huang G, Gilkeson G et al Genetic reconstitution of systemic lupus erythematosus immunopathology with polycongenic murine strains. Proc Natl Acad Sci USA 2000; 97: 6670-6675.
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 6670-6675
    • Morel, L.1    Croker, B.P.2    Blenman, K.R.3    Mohan, C.4    Huang, G.5    Gilkeson, G.6
  • 18
    • 0037025942 scopus 로고    scopus 로고
    • Genetic dissection of SLE: SLE1 and FAS impact alternate pathways leading to lymphoproliferative autoimmunity
    • Shi X, Xie C, Kreska D, Richardson JA, Mohan C. Genetic dissection of SLE: SLE1 and FAS impact alternate pathways leading to lymphoproliferative autoimmunity. J Exp Med 2002; 196: 281-292.
    • (2002) J Exp Med , vol.196 , pp. 281-292
    • Shi, X.1    Xie, C.2    Kreska, D.3    Richardson, J.A.4    Mohan, C.5
  • 20
    • 34848815714 scopus 로고    scopus 로고
    • CD19 hyper-expression augments Sle1-induced humoral autoimmunity but not clinical nephritis
    • Shi X, Xie C, Chang S, Zhou XJ, Tedder T, Mohan C. CD19 hyper-expression augments Sle1-induced humoral autoimmunity but not clinical nephritis. Arthritis Rheum 2007; 56: 3057-3069.
    • (2007) Arthritis Rheum , vol.56 , pp. 3057-3069
    • Shi, X.1    Xie, C.2    Chang, S.3    Zhou, X.J.4    Tedder, T.5    Mohan, C.6
  • 21
    • 0033825818 scopus 로고    scopus 로고
    • Genetics of systemic autoimmunity in mouse models of lupus
    • Kono DH, Theofilopoulos AN. Genetics of systemic autoimmunity in mouse models of lupus. Int Rev Immunol 2000; 19: 367-387.
    • (2000) Int Rev Immunol , vol.19 , pp. 367-387
    • Kono, D.H.1    Theofilopoulos, A.N.2
  • 22
    • 0035852650 scopus 로고    scopus 로고
    • The major murine systemic lupus erythematosus susceptibility locus, Sle1, is a cluster of functionally related genes
    • Morel L, Blenman KR, Croker BP, Wakeland EK. The major murine systemic lupus erythematosus susceptibility locus, Sle1, is a cluster of functionally related genes. Proc Natl Acad Sci USA 2001; 98: 1787-1792.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 1787-1792
    • Morel, L.1    Blenman, K.R.2    Croker, B.P.3    Wakeland, E.K.4
  • 23
    • 10344252778 scopus 로고    scopus 로고
    • Association of extensive polymorphisms in the SLAM/CD2 gene cluster with murine lupus
    • Wandstrat AE, Nguyen C, Limaye N, Chan AY, Subramanian S, Tian XH et al. Association of extensive polymorphisms in the SLAM/CD2 gene cluster with murine lupus. Immunity 2004; 21: 769-780.
    • (2004) Immunity , vol.21 , pp. 769-780
    • Wandstrat, A.E.1    Nguyen, C.2    Limaye, N.3    Chan, A.Y.4    Subramanian, S.5    Tian, X.H.6
  • 24
    • 33745161013 scopus 로고    scopus 로고
    • Regulation of B cell tolerance by the lupus susceptibility gene Ly108
    • Kumar KR, Li L, Yan M, Bhaskarabhatla M, Mobley AB, Nguyen C et al Regulation of B cell tolerance by the lupus susceptibility gene Ly108. Science 2006; 312: 1665-1669.
    • (2006) Science , vol.312 , pp. 1665-1669
    • Kumar, K.R.1    Li, L.2    Yan, M.3    Bhaskarabhatla, M.4    Mobley, A.B.5    Nguyen, C.6
  • 25
    • 23244454763 scopus 로고    scopus 로고
    • Several genes contribute to the production of autoreactive B and T cells in the murine lupus susceptibility locus Sle1c
    • Chen Y, Perry D, Boackle SA, Sobel ES, Molina H, Croker BP et al. Several genes contribute to the production of autoreactive B and T cells in the murine lupus susceptibility locus Sle1c. J Immunol 2005; 175: 1080-1089.
    • (2005) J Immunol , vol.175 , pp. 1080-1089
    • Chen, Y.1    Perry, D.2    Boackle, S.A.3    Sobel, E.S.4    Molina, H.5    Croker, B.P.6
  • 26
    • 0035652286 scopus 로고    scopus 로고
    • Cr2, a candidate gene in the murine Sle1c lupus susceptibility locus, encodes a dysfunctional protein
    • Boackle SA, Holers VM, Chen X, Szakonyi G, Karp DR, Wakeland EK et al. Cr2, a candidate gene in the murine Sle1c lupus susceptibility locus, encodes a dysfunctional protein. Immunity 2001; 15: 775-785.
    • (2001) Immunity , vol.15 , pp. 775-785
    • Boackle, S.A.1    Holers, V.M.2    Chen, X.3    Szakonyi, G.4    Karp, D.R.5    Wakeland, E.K.6
  • 27
    • 0036681645 scopus 로고    scopus 로고
    • A role for the Cr2 gene in modifying autoantibody production in systemic lupus erythematosus
    • Wu X, Jiang N, Deppong C, Singh J, Dolecki G, Mao D et al. A role for the Cr2 gene in modifying autoantibody production in systemic lupus erythematosus. J Immunol 2002; 169: 1587-1592.
    • (2002) J Immunol , vol.169 , pp. 1587-1592
    • Wu, X.1    Jiang, N.2    Deppong, C.3    Singh, J.4    Dolecki, G.5    Mao, D.6
  • 28
    • 33947626703 scopus 로고    scopus 로고
    • Augmentation of NZB autoimmune phenotypes by the Sle1c murine lupus susceptibility interval
    • Giles BM, Tchepeleva SN, Kachinski JJ, Ruff K, Croker BP, Morel L et al. Augmentation of NZB autoimmune phenotypes by the Sle1c murine lupus susceptibility interval. J Immunol 2007; 178: 4667-4675.
    • (2007) J Immunol , vol.178 , pp. 4667-4675
    • Giles, B.M.1    Tchepeleva, S.N.2    Kachinski, J.J.3    Ruff, K.4    Croker, B.P.5    Morel, L.6
  • 29
    • 0032546352 scopus 로고    scopus 로고
    • Dendritic cells and the control of immunity
    • Banchereau J, Steinman RM. Dendritic cells and the control of immunity. Nature 1998; 392: 245-252.
    • (1998) Nature , vol.392 , pp. 245-252
    • Banchereau, J.1    Steinman, R.M.2
  • 30
    • 33748455338 scopus 로고    scopus 로고
    • Type I interferons in host defense
    • Stetson DB, Medzhitov R. Type I interferons in host defense. Immunity 2006; 25: 373-381.
    • (2006) Immunity , vol.25 , pp. 373-381
    • Stetson, D.B.1    Medzhitov, R.2
  • 31
    • 33746028777 scopus 로고    scopus 로고
    • Intracellular pattern recognition receptors in the host response
    • Meylan E, Tschopp J, Karin M. Intracellular pattern recognition receptors in the host response. Nature 2006; 442: 39-44.
    • (2006) Nature , vol.442 , pp. 39-44
    • Meylan, E.1    Tschopp, J.2    Karin, M.3
  • 32
    • 0031893204 scopus 로고    scopus 로고
    • Genetic susceptibility to systemic lupus erythematosus
    • Vyse TJ, Kotzin BL. Genetic susceptibility to systemic lupus erythematosus. Annu Rev Immunol 1998; 16: 261-292.
    • (1998) Annu Rev Immunol , vol.16 , pp. 261-292
    • Vyse, T.J.1    Kotzin, B.L.2
  • 33
    • 1342282319 scopus 로고    scopus 로고
    • The centromeric region of chromosome 7 from MRL mice (Lmb3) is an epistatic modifier of Fas for autoimmune disease expression
    • Kong PL, Morel L, Croker BP, Craft J. The centromeric region of chromosome 7 from MRL mice (Lmb3) is an epistatic modifier of Fas for autoimmune disease expression. J Immunol 2004; 172: 2785-2794.
    • (2004) J Immunol , vol.172 , pp. 2785-2794
    • Kong, P.L.1    Morel, L.2    Croker, B.P.3    Craft, J.4
  • 34
    • 10344265955 scopus 로고    scopus 로고
    • Genetic dissection of lupus pathogenesis: Sle3/5 impacts IgH CDR3 sequences, somatic mutations, and receptor editing
    • Wakui M, Kim J, Butfiloski EJ, Morel L, Sobel ES. Genetic dissection of lupus pathogenesis: Sle3/5 impacts IgH CDR3 sequences, somatic mutations, and receptor editing. J Immunol 2004; 173: 7368-7376.
    • (2004) J Immunol , vol.173 , pp. 7368-7376
    • Wakui, M.1    Kim, J.2    Butfiloski, E.J.3    Morel, L.4    Sobel, E.S.5
  • 35
    • 22144457050 scopus 로고    scopus 로고
    • T cell hyperactivity in lupus as a consequence of hyperstimulatory antigen-presenting cells
    • Zhu J, Liu X, Xie C, Yan M, Yu Y, Sobel ES et al. T cell hyperactivity in lupus as a consequence of hyperstimulatory antigen-presenting cells. J Clin Invest 2005; 115: 1869-1878.
    • (2005) J Clin Invest , vol.115 , pp. 1869-1878
    • Zhu, J.1    Liu, X.2    Xie, C.3    Yan, M.4    Yu, Y.5    Sobel, E.S.6
  • 36
    • 33750348046 scopus 로고    scopus 로고
    • Aberrant phenotype and function of myeloid dendritic cells in systemic lupus erythematosus
    • Ding D, Mehta H, McCune WJ, Kaplan MJ. Aberrant phenotype and function of myeloid dendritic cells in systemic lupus erythematosus. J Immunol 2006; 177: 5878-5889.
    • (2006) J Immunol , vol.177 , pp. 5878-5889
    • Ding, D.1    Mehta, H.2    McCune, W.J.3    Kaplan, M.J.4
  • 37
    • 0035900481 scopus 로고    scopus 로고
    • Induction of dendritic cell differentiation by IFN-alpha in systemic lupus erythematosus
    • Blanco P, Palucka AK, Gill M, Pascual V, Banchereau J. Induction of dendritic cell differentiation by IFN-alpha in systemic lupus erythematosus. Science 2001; 294: 1540-1543.
    • (2001) Science , vol.294 , pp. 1540-1543
    • Blanco, P.1    Palucka, A.K.2    Gill, M.3    Pascual, V.4    Banchereau, J.5
  • 38
    • 0018572881 scopus 로고
    • A Y chromosome associated factor in strain BXSB producing accelerated autoimmunity and lymphoproliferation
    • Murphy ED, Roths JB. A Y chromosome associated factor in strain BXSB producing accelerated autoimmunity and lymphoproliferation. Arthritis Rheum 1979; 22: 1188-1194.
    • (1979) Arthritis Rheum , vol.22 , pp. 1188-1194
    • Murphy, E.D.1    Roths, J.B.2
  • 39
    • 0025038672 scopus 로고
    • Autoimmune accelerating genes, lpr and Yaa, in murine systemic lupus erythematosus
    • Izui S. Autoimmune accelerating genes, lpr and Yaa, in murine systemic lupus erythematosus. Autoimmunity 1990; 6: 113-129.
    • (1990) Autoimmunity , vol.6 , pp. 113-129
    • Izui, S.1
  • 40
    • 0021919112 scopus 로고
    • Effect of the BXSB Y chromosome accelerating gene on autoantibody production
    • Steinberg RT, Miller ML, Steinberg AD. Effect of the BXSB Y chromosome accelerating gene on autoantibody production. Clin Immunol Immunopathol 1985; 35: 67-72.
    • (1985) Clin Immunol Immunopathol , vol.35 , pp. 67-72
    • Steinberg, R.T.1    Miller, M.L.2    Steinberg, A.D.3
  • 42
    • 0023932750 scopus 로고
    • The Y chromosome from autoimmune BXSB/MpJ mice induces a lupus-like syndrome in (NZW x C57BL/6) F1 male mice, but not in C57BL/6 male mice
    • Izui S, Higaki M, Morrow D, Merino R. The Y chromosome from autoimmune BXSB/MpJ mice induces a lupus-like syndrome in (NZW x C57BL/6) F1 male mice, but not in C57BL/6 male mice. Eur J Immunol 1988; 18: 911-915.
    • (1988) Eur J Immunol , vol.18 , pp. 911-915
    • Izui, S.1    Higaki, M.2    Morrow, D.3    Merino, R.4
  • 44
    • 0034814052 scopus 로고    scopus 로고
    • Evidence for an interferon-inducible gene, Ifi202, in the susceptibility to systemic lupus
    • Rozzo S, Allard J, Choubey D, Vyse T, Izui S, Peltz G et al. Evidence for an interferon-inducible gene, Ifi202, in the susceptibility to systemic lupus. Immunity 2002; 15: 435-443.
    • (2002) Immunity , vol.15 , pp. 435-443
    • Rozzo, S.1    Allard, J.2    Choubey, D.3    Vyse, T.4    Izui, S.5    Peltz, G.6
  • 45
    • 33646475561 scopus 로고    scopus 로고
    • Increased expression of Ifi202, an IFN-activatable gene, in B6.Nba2 lupus susceptible mice inhibits p53-mediated apoptosis
    • Xin H, D'Souza S, Jorgensen TN, Vaughan AT, Lengyel P, Kotzin BL et al. Increased expression of Ifi202, an IFN-activatable gene, in B6.Nba2 lupus susceptible mice inhibits p53-mediated apoptosis. J Immunol 2006; 176: 5863-5870.
    • (2006) J Immunol , vol.176 , pp. 5863-5870
    • Xin, H.1    D'Souza, S.2    Jorgensen, T.N.3    Vaughan, A.T.4    Lengyel, P.5    Kotzin, B.L.6
  • 46
    • 44449146089 scopus 로고    scopus 로고
    • Disruption of mutually negative regulatory feedback loop between interferon-inducible p202 protein and the E2F family of transcription factors in lupus-prone mice
    • Panchanathan R, Xin H, Choubey D. Disruption of mutually negative regulatory feedback loop between interferon-inducible p202 protein and the E2F family of transcription factors in lupus-prone mice. J Immunol 2008; 180: 5927-5934.
    • (2008) J Immunol , vol.180 , pp. 5927-5934
    • Panchanathan, R.1    Xin, H.2    Choubey, D.3
  • 47
    • 36048946330 scopus 로고    scopus 로고
    • Roquin represses autoimmunity by limiting inducible T-cell co-stimulator messenger RNA
    • Yu D, Tan AH, Hu X, Athanasopoulos V, Simpson N, Silva DG et al. Roquin represses autoimmunity by limiting inducible T-cell co-stimulator messenger RNA. Nature 2007; 450: 299-303.
    • (2007) Nature , vol.450 , pp. 299-303
    • Yu, D.1    Tan, A.H.2    Hu, X.3    Athanasopoulos, V.4    Simpson, N.5    Silva, D.G.6
  • 49
    • 0033180576 scopus 로고    scopus 로고
    • Epistatic modifiers of autoimmunity in a murine model of lupus nephritis
    • Morel L, Tian XH, Croker BP, Wakeland EK. Epistatic modifiers of autoimmunity in a murine model of lupus nephritis. Immunity 1999; 11: 131-139.
    • (1999) Immunity , vol.11 , pp. 131-139
    • Morel, L.1    Tian, X.H.2    Croker, B.P.3    Wakeland, E.K.4
  • 50
    • 0032493059 scopus 로고    scopus 로고
    • Antibodies to DNA
    • Hahn BH. Antibodies to DNA. N Engl J Med 1998; 338: 1359.
    • (1998) N Engl J Med , vol.338 , pp. 1359
    • Hahn, B.H.1
  • 51
    • 0029899083 scopus 로고    scopus 로고
    • Nephritogenic autoantibodies in lupus. Current concepts and continuing controversies
    • Lefkowith JB, Gilkeson GS. Nephritogenic autoantibodies in lupus. Current concepts and continuing controversies. Arthritis Rheum 1996; 39: 894.
    • (1996) Arthritis Rheum , vol.39 , pp. 894
    • Lefkowith, J.B.1    Gilkeson, G.S.2
  • 52
    • 0030784483 scopus 로고    scopus 로고
    • A role for Mac-1 (CDllb/CD18) in immune complex-stimulated neutrophil function in vivo: Mac-1 deficiency abrogates sustained Fcgamma receptor-dependent neutrophil adhesion and complement-dependent proteinuria in acute glomerulonephritis
    • Tang T, Rosenkranz A, Assmann KM, Goodman MJ, Gutierrez-Ramos JC, Carroll MC et al. A role for Mac-1 (CDllb/CD18) in immune complex-stimulated neutrophil function in vivo: Mac-1 deficiency abrogates sustained Fcgamma receptor-dependent neutrophil adhesion and complement-dependent proteinuria in acute glomerulonephritis. J Exp Med 1997; 186: 1853.
    • (1997) J Exp Med , vol.186 , pp. 1853
    • Tang, T.1    Rosenkranz, A.2    Assmann, K.M.3    Goodman, M.J.4    Gutierrez-Ramos, J.C.5    Carroll, M.C.6
  • 53
    • 0031725199 scopus 로고    scopus 로고
    • Acute nephrotoxic serum nephritis in complement knockout mice: Relative roles of the classical and alternate pathways in neutrophil recruitment and proteinuria
    • Hebert MJ, Takano T, Papayianni A, Rennke HG, Minto A, Salant DJ et al. Acute nephrotoxic serum nephritis in complement knockout mice: relative roles of the classical and alternate pathways in neutrophil recruitment and proteinuria. Nephrol Dial Transplant 1998; 13 2799.
    • (1998) Nephrol Dial Transplant , vol.13 , pp. 2799
    • Hebert, M.J.1    Takano, T.2    Papayianni, A.3    Rennke, H.G.4    Minto, A.5    Salant, D.J.6
  • 54
    • 0031702690 scopus 로고    scopus 로고
    • Distinct contribution of Fc receptors and angiotensin II-dependent pathways in anti-GBM glomerulonephritis
    • Suzuki Y, Shirato I, Okumura K, Ravetch JV, Takai T, Tomino Y et al Distinct contribution of Fc receptors and angiotensin II-dependent pathways in anti-GBM glomerulonephritis. Kidney Int 1998; 54 1166.
    • (1998) Kidney Int , vol.54 , pp. 1166
    • Suzuki, Y.1    Shirato, I.2    Okumura, K.3    Ravetch, J.V.4    Takai, T.5    Tomino, Y.6
  • 55
    • 0032512855 scopus 로고    scopus 로고
    • Uncoupling of immune complex formation and kidney damage in autoimmune glomerulonephritis
    • Clynes R, Dumitru C, Ravetch JV. Uncoupling of immune complex formation and kidney damage in autoimmune glomerulonephritis. Science 1998; 279: 1052.
    • (1998) Science , vol.279 , pp. 1052
    • Clynes, R.1    Dumitru, C.2    Ravetch, J.V.3
  • 56
    • 0032434379 scopus 로고    scopus 로고
    • Prevention of crescentic glomerulonephritis induced by anti-glomerular membrane antibody in tumor necrosis factor-deficient mice
    • Le Hir M, Haas C, Marino M, Ryffel B. Prevention of crescentic glomerulonephritis induced by anti-glomerular membrane antibody in tumor necrosis factor-deficient mice. Lab Invest 1998; 78: 1625.
    • (1998) Lab Invest , vol.78 , pp. 1625
    • Le Hir, M.1    Haas, C.2    Marino, M.3    Ryffel, B.4
  • 57
    • 0031665608 scopus 로고    scopus 로고
    • Improved survival and amelioration of nephrotoxic nephritis in intercellular adhesion molecule-1 knockout mice
    • Janssen U, Ostendorf T, Gaertner S, Eitner F, Hedrich HJ, Assmann KJ et al. Improved survival and amelioration of nephrotoxic nephritis in intercellular adhesion molecule-1 knockout mice. J Am Soc Nephrol 1998; 9: 1805.
    • (1998) J Am Soc Nephrol , vol.9 , pp. 1805
    • Janssen, U.1    Ostendorf, T.2    Gaertner, S.3    Eitner, F.4    Hedrich, H.J.5    Assmann, K.J.6
  • 58
    • 34547414073 scopus 로고    scopus 로고
    • The genetics of systemic lupus erythematosus stratified by renal disease: Linkage at 10q22.3 (SLEN1), 2q34-35 (SLEN2), and 11p15.6 (SLEN3)
    • Quintero-Del-Rio AI, Kelly JA, Kilpatrick J, James JA, Harley JB. The genetics of systemic lupus erythematosus stratified by renal disease: linkage at 10q22.3 (SLEN1), 2q34-35 (SLEN2), and 11p15.6 (SLEN3). Genes Immun 2002; 3(Suppl 1): S57-S62.
    • (2002) Genes Immun , vol.3 , Issue.SUPPL. 1
    • Quintero-Del-Rio, A.I.1    Kelly, J.A.2    Kilpatrick, J.3    James, J.A.4    Harley, J.B.5
  • 61
    • 0034051681 scopus 로고    scopus 로고
    • Mutations in ACTN4, encoding alpha-actinin-4, cause familial focal segmental glomerulosclerosis
    • Kaplan JM, Kim SH, North KN, Rennke H, Correia LA, Tong HO et al. Mutations in ACTN4, encoding alpha-actinin-4, cause familial focal segmental glomerulosclerosis. Nat Genet 2000; 24: 251-256.
    • (2000) Nat Genet , vol.24 , pp. 251-256
    • Kaplan, J.M.1    Kim, S.H.2    North, K.N.3    Rennke, H.4    Correia, L.A.5    Tong, H.O.6
  • 63
    • 0029053741 scopus 로고
    • Familia/predisposition to nephropathy in African-Americans with non-insulin-dependent diabetes mellitus
    • Freedman BI, Tuttle AB, Spray BJ. Familia/predisposition to nephropathy in African-Americans with non-insulin-dependent diabetes mellitus. Am J Kidney Dis 1995; 25: 710-713.
    • (1995) Am J Kidney Dis , vol.25 , pp. 710-713
    • Freedman, B.I.1    Tuttle, A.B.2    Spray, B.J.3
  • 65
    • 0029867191 scopus 로고    scopus 로고
    • Kidney disease in the first-degree relatives of African-Americans with hypertensive end-stage renal disease
    • Bergman S, Key BO, Kirk KA, Warnock DG, Rostant SG. Kidney disease in the first-degree relatives of African-Americans with hypertensive end-stage renal disease. Am J Kidney Dis 1996; 27: 341-346.
    • (1996) Am J Kidney Dis , vol.27 , pp. 341-346
    • Bergman, S.1    Key, B.O.2    Kirk, K.A.3    Warnock, D.G.4    Rostant, S.G.5
  • 66
    • 0012903732 scopus 로고
    • Glomerulonephritis durch das spezifische anti-nierenserum: Ein Beitrag zur Pathogenese der diffusen Glomerulonephritis.
    • Masugi M. Glomerulonephritis durch das spezifische anti-nierenserum: Ein Beitrag zur Pathogenese der diffusen Glomerulonephritis. Beitr Pathol Anat Allg Pathol 1934; 92: 429.
    • (1934) Beitr Pathol Anat Allg Pathol , vol.92 , pp. 429
    • Masugi, M.1
  • 67
    • 34447315527 scopus 로고    scopus 로고
    • The experimental anti-GBM model as a tool for studying spontaneous lupus nephritis
    • Fu Y, Yong D, Mohan C. The experimental anti-GBM model as a tool for studying spontaneous lupus nephritis. Clin Immunol 2007; 124 109-118.
    • (2007) Clin Immunol , vol.124 , pp. 109-118
    • Fu, Y.1    Yong, D.2    Mohan, C.3
  • 69
    • 54549093861 scopus 로고    scopus 로고
    • The genetics of SLE: An update in the light of genome-wide association studies
    • Rhodes B, Vyse TJ. The genetics of SLE: An update in the light of genome-wide association studies. Rheumatology 2008; 47: 1603-1611.
    • (2008) Rheumatology , vol.47 , pp. 1603-1611
    • Rhodes, B.1    Vyse, T.J.2
  • 70
    • 0037080952 scopus 로고    scopus 로고
    • BANK regulates BCR-induced calcium mobilization by promoting tyrosine phosphorylation of IP3 receptor
    • Yokoyama K, Su I, Tezuka T, Yasuda T, Mikoshiba K, Tarakhovsky A et al. BANK regulates BCR-induced calcium mobilization by promoting tyrosine phosphorylation of IP3 receptor. EMBO J 2002; 21: 83-92.
    • (2002) EMBO J , vol.21 , pp. 83-92
    • Yokoyama, K.1    Su, I.2    Tezuka, T.3    Yasuda, T.4    Mikoshiba, K.5    Tarakhovsky, A.6
  • 71
    • 0026630056 scopus 로고
    • Structure and developmental regulation of the B-lymphoid tyrosine kinase gene blk
    • Dymecki SM, Zwollo P, Zeller K, Kuhajda FP, Desiderio SV. Structure and developmental regulation of the B-lymphoid tyrosine kinase gene blk. J Biol Chem 1992; 267: 4815-4823.
    • (1992) J Biol Chem , vol.267 , pp. 4815-4823
    • Dymecki, S.M.1    Zwollo, P.2    Zeller, K.3    Kuhajda, F.P.4    Desiderio, S.V.5
  • 72
    • 0029009398 scopus 로고
    • Differential expression of the blk and ret tyrosine kinases during B lineage development is dependent on Ig rearrangement
    • Wasserman R, Li YS, Hardy RR. Differential expression of the blk and ret tyrosine kinases during B lineage development is dependent on Ig rearrangement. J Immunol 1995; 155: 644-651.
    • (1995) J Immunol , vol.155 , pp. 644-651
    • Wasserman, R.1    Li, Y.S.2    Hardy, R.R.3
  • 73
    • 0033990632 scopus 로고    scopus 로고
    • The role of complement in B cell activation and tolerance
    • Carroll MC. The role of complement in B cell activation and tolerance. Adv Immunol 2000; 74: 61-88.
    • (2000) Adv Immunol , vol.74 , pp. 61-88
    • Carroll, M.C.1
  • 74
    • 0037324434 scopus 로고    scopus 로고
    • Tolerance is dependent on complement C3 fragment iC3b binding to antigen-presenting cells
    • Sohn JH, Bora PS, Suk HJ, Molina H, Kaplan HJ, Bora NS. Tolerance is dependent on complement C3 fragment iC3b binding to antigen-presenting cells. Nat Med 2003; 9: 206-212.
    • (2003) Nat Med , vol.9 , pp. 206-212
    • Sohn, J.H.1    Bora, P.S.2    Suk, H.J.3    Molina, H.4    Kaplan, H.J.5    Bora, N.S.6
  • 77
    • 5444223519 scopus 로고    scopus 로고
    • The ubiquitin-modifying enzyme A20 is required for termination of Toll-like receptor responses
    • Boone DL, Turer EE, Lee EG, Ahmad R-C, Wheeler MT, Tsui C et al. The ubiquitin-modifying enzyme A20 is required for termination of Toll-like receptor responses. Nat Immunol 2004; 5: 1052-1060.
    • (2004) Nat Immunol , vol.5 , pp. 1052-1060
    • Boone, D.L.1    Turer, E.E.2    Lee, E.G.3    Ahmad, R.-C.4    Wheeler, M.T.5    Tsui, C.6
  • 78
    • 20444380445 scopus 로고    scopus 로고
    • The interferon regulatory factor, IRF5, is a central mediator of Toll-like receptor 7 signaling
    • Schoenemeyer A, Barnes BJ, Mancl ME, Latz E, Goutagny N, Pitha PM et al. The interferon regulatory factor, IRF5, is a central mediator of Toll-like receptor 7 signaling. J Biol Chem 2005; 280: 17005-17012.
    • (2005) J Biol Chem , vol.280 , pp. 17005-17012
    • Schoenemeyer, A.1    Barnes, B.J.2    Mancl, M.E.3    Latz, E.4    Goutagny, N.5    Pitha, P.M.6
  • 79
    • 0029938992 scopus 로고    scopus 로고
    • The T cell-B cell interaction via OX40-OX40L is necessary for the T cell-dependent humoral immune response
    • Stuber E, Strober W. The T cell-B cell interaction via OX40-OX40L is necessary for the T cell-dependent humoral immune response. J Exp Med 1996; 183: 979-989.
    • (1996) J Exp Med , vol.183 , pp. 979-989
    • Stuber, E.1    Strober, W.2
  • 81
    • 0034927194 scopus 로고    scopus 로고
    • PD-1: An inhibitory immunoreceptor involved in peripheral tolerance
    • Nishimura H, Honjo T. PD-1: An inhibitory immunoreceptor involved in peripheral tolerance. Trends Immunol 2001; 22: 265-268.
    • (2001) Trends Immunol , vol.22 , pp. 265-268
    • Nishimura, H.1    Honjo, T.2
  • 83
    • 0041344320 scopus 로고    scopus 로고
    • Pivotal role of Stat4 and Stat6 in the pathogenesis of the Lupus-like disease in the New Zealand mixed 2328 mice
    • Jacob CO, Zang S, Li L, Ciobanu V, Quismorio F, Mizutani A et al. Pivotal role of Stat4 and Stat6 in the pathogenesis of the Lupus-like disease in the New Zealand mixed 2328 mice. J Immunol 2003; 171 1564-1571.
    • (2003) J Immunol , vol.171 , pp. 1564-1571
    • Jacob, C.O.1    Zang, S.2    Li, L.3    Ciobanu, V.4    Quismorio, F.5    Mizutani, A.6
  • 84
    • 0032080799 scopus 로고    scopus 로고
    • Blockade of antibody-induced glomerulonephritis with Crry-Ig, a soluble murine complement inhibitor
    • Quigg RJ, Kozono Y, Berthiaume D, Lim A, Salant DJ, Weinfeld A et al Blockade of antibody-induced glomerulonephritis with Crry-Ig, a soluble murine complement inhibitor. J Immunol 1998; 160: 4553-4560.
    • (1998) J Immunol , vol.160 , pp. 4553-4560
    • Quigg, R.J.1    Kozono, Y.2    Berthiaume, D.3    Lim, A.4    Salant, D.J.5    Weinfeld, A.6
  • 85
    • 84883832799 scopus 로고
    • A role of polymorphonuclear leukocytes and complement in nephrotoxic nephritis
    • Cochrane CG, Unanue ER, Dixon FJ. A role of polymorphonuclear leukocytes and complement in nephrotoxic nephritis. J Exp Med 1965; 122 99-116.
    • (1965) J Exp Med , vol.122 , pp. 99-116
    • Cochrane, C.G.1    Unanue, E.R.2    Dixon, F.J.3
  • 86
    • 0345447594 scopus 로고    scopus 로고
    • Mac-1, but not LFA-1, uses intercellular adhesion molecule-1 to mediate slow leukocyte rolling in TNF-alpha-induced inflammation
    • Dunne JL, Collins RG, Beaudet AL, Ballantyne CM, Ley K. Mac-1, but not LFA-1, uses intercellular adhesion molecule-1 to mediate slow leukocyte rolling in TNF-alpha-induced inflammation. J Immunol 2003; 171 6105-6111.
    • (2003) J Immunol , vol.171 , pp. 6105-6111
    • Dunne, J.L.1    Collins, R.G.2    Beaudet, A.L.3    Ballantyne, C.M.4    Ley, K.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.