Plasma leakage through glomerular basement membrane ruptures triggers the proliferation of parietal epithelial cells and crescent formation in non-inflammatory glomerular injury

Journal of Pathology

Volumn 228, Issue 4, 2012, Pages 482-494

  Ryu, Mi ^a   Migliorini, Adriana ^a   Miosge, Nicolai ^b   Gross, Oliver ^c   Shankland, Stuart ^d   Brinkkoetter, Paul T ^e   Hagmann, Henning ^e   Romagnani, Paola ^f   Liapis, Helen ^g   Anders, Hans Joachim ^a  

^a LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

^b UNIVERSITY OF GÖTTINGEN   (Germany)

^c UNIVERSITY MEDICAL CENTER GÖTTINGEN   (Germany)

^d UNIVERSITY OF WASHINGTON MEDICAL CENTER   (United States)

^e UNIVERSITY OF COLOGNE   (Germany)

^f UNIVERSITY OF FLORENCE   (Italy)

^g WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Alport; Chronic kidney disease; Collagen; Crescent; Glomerulosclerosis; Parietal epithelial cells

Indexed keywords

LAMININ; RECOMBINANT UROKINASE; COLLAGEN TYPE 4; FIBRIN; FLUORESCEIN ISOTHIOCYANATE DEXTRAN; AUTOANTIGEN; PLASMA PROTEIN; TYPE IV COLLAGEN ALPHA3 CHAIN; UROKINASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD VESSEL INJURY; CELL PROLIFERATION; CELL TYPE; CONTROLLED STUDY; EPITHELIUM CELL; FIBRINOLYSIS; GLOMERULAR BASEMENT MEMBRANE RUPTURE; GLOMERULONEPHRITIS; IN VITRO STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL; SCANNING ELECTRON MICROSCOPY; TRANSMISSION ELECTRON MICROSCOPY; ALPORT SYNDROME; BLOOD VESSEL PERMEABILITY; CELLS BY BODY ANATOMY; GLOMERULOPATHY; GLOMERULUS BASEMENT MEMBRANE; GLOMERULUS CAPILLARY; HISTOPATHOLOGY; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; KIDNEY RUPTURE; PARIETAL EPITHELIAL CELL; PLASMA; WOUND HEALING; 129 MOUSE; ADOLESCENT; ADULT; ANIMAL; CELL POLARITY; DISEASE COURSE; DISEASE MODEL; DRUG EFFECTS; FEMALE; GENETICS; KNOCKOUT MOUSE; MALE; METABOLISM; NEPHRITIS, HEREDITARY; PATHOLOGY; PHYSIOLOGY; PRIMARY CELL CULTURE; TRANSFORMED CELL LINE;

ADOLESCENT; ADULT; ANIMALS; AUTOANTIGENS; BLOOD PROTEINS; CELL LINE, TRANSFORMED; CELL POLARITY; CELL PROLIFERATION; COLLAGEN TYPE IV; DISEASE MODELS, ANIMAL; DISEASE PROGRESSION; EPITHELIAL CELLS; FEMALE; FIBRINOLYSIS; GLOMERULAR BASEMENT MEMBRANE; HUMANS; MALE; MICE, 129 STRAIN; MICE, KNOCKOUT; NEPHRITIS, HEREDITARY; PRIMARY CELL CULTURE; UROKINASE-TYPE PLASMINOGEN ACTIVATOR; WOUND HEALING;

EID: 84871256661     PISSN: 00223417     EISSN: 10969896     Source Type: Journal    
DOI: 10.1002/path.4046     Document Type: Article

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